PubRank

Mark A Atkinson

Author PubWeight™ 138.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med 2007 5.48
2 Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol 2007 3.08
3 A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity 2005 3.07
4 Toward defining the autoimmune microbiome for type 1 diabetes. ISME J 2010 3.03
5 Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J Exp Med 2012 2.86
6 The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes 2008 2.77
7 Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes. Diabetes 2005 2.63
8 Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes 2008 2.52
9 A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol 2007 2.23
10 Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. PLoS One 2011 2.18
11 Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. Am J Pathol 2004 2.09
12 In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow. Diabetes 2004 2.01
13 Formation of a human β-cell population within pancreatic islets is set early in life. J Clin Endocrinol Metab 2012 2.01
14 B cells enhance early innate immune responses during bacterial sepsis. J Exp Med 2011 1.99
15 Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. J Immunol 2006 1.86
16 Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. J Clin Invest 2012 1.84
17 Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model. ISME J 2009 1.74
18 Why can't we prevent type 1 diabetes?: maybe it's time to try a different combination. Diabetes Care 2003 1.71
19 Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. PLoS One 2010 1.70
20 Influence of fecal sample storage on bacterial community diversity. Open Microbiol J 2009 1.68
21 Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 2007 1.63
22 Pancreas organ weight in individuals with disease-associated autoantibodies at risk for type 1 diabetes. JAMA 2012 1.57
23 Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice. Diabetes 2009 1.48
24 The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings. Pediatr Diabetes 2013 1.46
25 It's time to consider changing the rules: the rationale for rethinking control groups in clinical trials aimed at reversing type 1 diabetes. Diabetes 2011 1.42
26 IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol 2005 1.41
27 Autologous umbilical cord blood infusion for type 1 diabetes. Exp Hematol 2008 1.34
28 Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias. J Immunol 2011 1.34
29 Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion. J Immunol 2003 1.32
30 Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials. Diabetes 2013 1.30
31 Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood 2007 1.29
32 Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells. Am J Pathol 2008 1.25
33 Autologous umbilical cord blood transfusion in very young children with type 1 diabetes. Diabetes Care 2009 1.24
34 Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway. Proc Natl Acad Sci U S A 2005 1.22
35 Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. J Clin Invest 2014 1.22
36 Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation. Diabetes 2007 1.22
37 Type 1 diabetes mellitus: etiology, presentation, and management. Pediatr Clin North Am 2005 1.21
38 Bioluminescent monitoring of islet graft survival after transplantation. Mol Ther 2004 1.21
39 IL-10 regulation of lupus in the NZM2410 murine model. Lab Invest 2006 1.21
40 Central role for interleukin-2 in type 1 diabetes. Diabetes 2012 1.19
41 Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice. Am J Pathol 2009 1.19
42 Autoantibody markers for the diagnosis and prediction of type 1 diabetes. Autoimmun Rev 2005 1.19
43 Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors. Hum Gene Ther 2005 1.17
44 An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells. J Immunol 2005 1.16
45 Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice. Brain Res 2005 1.13
46 Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes. Diabetes 2011 1.13
47 Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies. Diabetes 2011 1.12
48 The pancreas in human type 1 diabetes. Semin Immunopathol 2010 1.11
49 Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation. J Immunol 2011 1.10
50 Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy. Diabetes 2007 1.08
51 Novel synthesis of cerium oxide nanoparticles for free radical scavenging. Nanomedicine (Lond) 2007 1.05
52 Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation. Lab Invest 2006 1.05
53 Noninvasive imaging of islet grafts using positron-emission tomography. Proc Natl Acad Sci U S A 2006 1.04
54 Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury. Diabetes 2006 1.03
55 Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. PLoS One 2010 1.03
56 Assessing the in vitro suppressive capacity of regulatory T cells. Immunol Invest 2007 1.02
57 Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma. Cancer Immunol Immunother 2012 1.00
58 Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice. Diabetes 2003 0.99
59 Multimodality imaging of β-cells in mouse models of type 1 and 2 diabetes. Diabetes 2011 0.99
60 Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med 2012 0.98
61 The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Lab Invest 2008 0.98
62 Persistence is the twin sister of excellence: an important lesson for attempts to prevent and reverse type 1 diabetes. Diabetes 2011 0.96
63 Uncoupling of vascular endothelial growth factor with nitric oxide as a mechanism for diabetic vasculopathy. J Am Soc Nephrol 2006 0.96
64 Type 1 diabetes alters anti-hsp90 autoantibody isotype. J Autoimmun 2003 0.95
65 Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon. J Virol 2005 0.95
66 Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation. PLoS One 2009 0.95
67 γ-Aminobutyric acid regulates both the survival and replication of human β-cells. Diabetes 2013 0.95
68 Collection protocol for human pancreas. J Vis Exp 2012 0.94
69 Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency. Ann N Y Acad Sci 2008 0.94
70 Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors. J Am Soc Nephrol 2003 0.94
71 Long-term monitoring of transplanted islets using positron emission tomography. Mol Ther 2006 0.93
72 Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2rγnull Ins2Akita mice. Pancreas 2011 0.93
73 New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation. Curr Diab Rep 2014 0.93
74 Hepatocellular carcinoma immunopathogenesis: clinical evidence for global T cell defects and an immunomodulatory role for soluble CD25 (sCD25). Dig Dis Sci 2010 0.93
75 Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes Care 2011 0.93
76 A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository? Curr Opin Endocrinol Diabetes Obes 2015 0.91
77 In vitro generation of functional insulin-producing cells from human bone marrow-derived stem cells, but long-term culture running risk of malignant transformation. Am J Stem Cells 2012 0.89
78 Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model. J Transl Med 2011 0.89
79 Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic cell profile and function in NOD mice to suppress diabetogenic responses. J Immunol 2009 0.89
80 Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts. Mol Ther 2005 0.88
81 The Juvenile Diabetes Research Foundation at forty: updates of research in type 1 diabetes. Diabetes 2010 0.87
82 Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area. J Diabetes Complications 2009 0.85
83 Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis. Diabetes 2005 0.85
84 Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes 2013 0.85
85 Neonatal formula feeding leads to immunological alterations in an animal model of type 1 diabetes. Pediatr Res 2008 0.85
86 Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice. BMC Immunol 2012 0.84
87 Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis. Diabetes 2006 0.84
88 Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak? J Pediatr Gastroenterol Nutr 2010 0.84
89 Glucose transporter-2 (GLUT2) promoter mediated transgenic insulin production reduces hyperglycemia in diabetic mice. FEBS Lett 2005 0.84
90 Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice. Lab Invest 2006 0.84
91 Efficient delivery of siRNA into cytokine-stimulated insulinoma cells silences Fas expression and inhibits Fas-mediated apoptosis. FEBS Lett 2005 0.83
92 Beta-cell destruction and preservation in childhood and adult onset type 1 diabetes. Endocrine 2015 0.83
93 Murine model for cystic fibrosis bone disease demonstrates osteopenia and sex-related differences in bone formation. Pediatr Res 2009 0.83
94 Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. Biol Blood Marrow Transplant 2013 0.83
95 Mental state attribution and the gaze cueing effect. Atten Percept Psychophys 2015 0.81
96 The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus. Arthritis Res Ther 2013 0.81
97 PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene 2006 0.80
98 Serum levels of soluble CD25 as a marker for hepatocellular carcinoma. Oncol Lett 2012 0.80
99 Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice. Transplantation 2005 0.80
100 Comparative analysis of the islet proteome between NOD/Lt and ALR/Lt mice. Ann N Y Acad Sci 2008 0.80
101 The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes. Ann N Y Acad Sci 2007 0.80
102 CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes. Cytokine 2008 0.80
103 Efforts to prevent and halt autoimmune beta cell destruction. Endocrinol Metab Clin North Am 2010 0.78
104 The road not taken: a path to curing type 1 diabetes? Eur J Immunol 2009 0.78
105 The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC. J Autoimmun 2013 0.77
106 Taking a daily vitamin to prevent type 1 diabetes? Diabetes 2009 0.77
107 The IDS conducts standardization of assays for the measurement of autoantibodies and of T cells in autoimmune diabetes. Preface. Ann N Y Acad Sci 2008 0.76
108 Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation. Transplantation 2002 0.76
109 Factors That Influence the Quality of RNA From the Pancreas of Organ Donors. Pancreas 2016 0.75
110 Islet cell autoantibodies: a case of a premature obituary. Pediatr Diabetes 2005 0.75
111 Global reality of type 1 diabetes care in 2013. Diabetes Care 2013 0.75
112 It's time to mow the GRAS in type 1 diabetes. Diabetes 2011 0.75
113 Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med 2017 0.75
114 Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat Med 2017 0.75
115 Are Goal States Represented During Kinematic Imitation? J Exp Psychol Hum Percept Perform 2017 0.75
116 Type I diabetes. Preface. Endocrinol Metab Clin North Am 2010 0.75