Published in Mol Cancer on July 13, 2011
Human RecQ helicases in DNA repair, recombination, and replication. Annu Rev Biochem (2014) 1.68
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol (2013) 1.67
DNA helicases involved in DNA repair and their roles in cancer. Nat Rev Cancer (2013) 1.58
DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol (2015) 1.27
Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D. Mol Cancer (2013) 0.94
Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion. Cell Cycle (2014) 0.92
RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures. Cell Cycle (2012) 0.91
RECQL1 DNA repair helicase: a potential therapeutic target and a proliferative marker against ovarian cancer. PLoS One (2013) 0.91
Human RECQL1 participates in telomere maintenance. Nucleic Acids Res (2014) 0.90
An appraisal of RECQ1 expression in cancer progression. Front Genet (2014) 0.88
Unwinding and rewinding: double faces of helicase? J Nucleic Acids (2012) 0.86
RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers. Front Genet (2015) 0.85
Catalytic Strand Separation by RECQ1 Is Required for RPA-Mediated Response to Replication Stress. Curr Biol (2015) 0.81
Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers. Mol Cancer Ther (2016) 0.75
A new sub-pathway of long-patch base excision repair involving 5' gap formation. EMBO J (2017) 0.75
RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704. Int J Radiat Oncol Biol Phys (2015) 0.75
RECQ1 Helicase Silencing Decreases the Tumour Growth Rate of U87 Glioblastoma Cell Xenografts in Zebrafish Embryos. Genes (Basel) (2017) 0.75
RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma. Leukemia (2017) 0.75
An integrated genomic analysis of human glioblastoma multiforme. Science (2008) 51.36
IDH1 and IDH2 mutations in gliomas. N Engl J Med (2009) 32.41
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol (2009) 25.96
Clonogenic assay of cells in vitro. Nat Protoc (2006) 11.85
Positional cloning of the Werner's syndrome gene. Science (1996) 10.98
The Bloom's syndrome gene product is homologous to RecQ helicases. Cell (1995) 9.91
RecQ helicases: caretakers of the genome. Nat Rev Cancer (2003) 5.83
RecQ helicases: multifunctional genome caretakers. Nat Rev Cancer (2009) 3.63
Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol (2005) 3.46
The histone code at DNA breaks: a guide to repair? Nat Rev Mol Cell Biol (2005) 2.97
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine. Oncogene (2006) 2.82
RecQ helicases: guardian angels of the DNA replication fork. Chromosoma (2008) 2.43
DNA helicases required for homologous recombination and repair of damaged replication forks. Annu Rev Genet (2006) 2.43
NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA. Biochemistry (1994) 2.27
Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance. Trends Biochem Sci (2008) 2.24
Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability. Biochem J (2006) 1.99
Proautophagic drugs: a novel means to combat apoptosis-resistant cancers, with a special emphasis on glioblastomas. Oncologist (2007) 1.85
Human premature aging, DNA repair and RecQ helicases. Nucleic Acids Res (2007) 1.84
Involvement of the mismatch repair system in temozolomide-induced apoptosis. Mol Pharmacol (1998) 1.83
Rothmund-thomson syndrome responsible gene, RECQL4: genomic structure and products. Genomics (1999) 1.65
Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A. Nucleic Acids Res (2004) 1.60
Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases. Hum Mol Genet (2003) 1.55
RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability. Mol Cell Biol (2006) 1.54
Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer. J Clin Oncol (2006) 1.53
The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities. J Biol Chem (2008) 1.52
Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation. Mol Cell Biol (2010) 1.50
Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene. J Med Genet (2005) 1.46
Differential regulation of human RecQ family helicases in cell transformation and cell cycle. Oncogene (2000) 1.46
3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity. Br J Cancer (1996) 1.38
Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges. PLoS One (2007) 1.38
Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. Cancer Res (2006) 1.36
Junction of RecQ helicase biochemistry and human disease. J Biol Chem (2004) 1.34
DNA damage responses and their many interactions with the replication fork. Carcinogenesis (2006) 1.32
Homologous recombination and maintenance of genome integrity: cancer and aging through the prism of human RecQ helicases. Mech Ageing Dev (2008) 1.26
Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein. EMBO J (2003) 1.26
Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase. Cancer Sci (2007) 1.23
Role for the Werner syndrome protein in the promotion of tumor cell growth. Mech Ageing Dev (2007) 1.10
Proteomic studies on low- and high-grade human brain astrocytomas. J Proteome Res (2005) 1.06
Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models. Cancer Sci (2008) 1.06
Mutation profiling of mismatch repair-deficient colorectal cncers using an in silico genome scan to identify coding microsatellites. Cancer Res (2002) 1.05
Probing the structural basis of RecQ helicase function. Biophys Chem (2010) 1.04
RecQL1 DNA repair helicase: A potential tumor marker and therapeutic target against hepatocellular carcinoma. Int J Mol Med (2010) 1.01
RECQL1 and WRN proteins are potential therapeutic targets in head and neck squamous cell carcinoma. Cancer Res (2011) 1.01
Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia. Leukemia (2004) 1.00
DNA helicases as targets for anti-cancer drugs. Curr Med Chem Anticancer Agents (2005) 1.00
Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers. Int J Oncol (2005) 1.00
Molecular diagnostics of gliomas. Arch Pathol Lab Med (2011) 0.96
Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide. Br J Cancer (2003) 0.92
The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells. Br J Cancer (2001) 0.87
DNA repair helicases as targets for anti-cancer therapy. Curr Med Chem (2007) 0.86
A chronic myeloid leukemia-like syndrome case with del (12) (p12) in a Li-Fraumeni syndrome family. Clin Lab Haematol (2005) 0.81
DNA repair is limiting for haematopoietic stem cells during ageing. Nature (2007) 4.71
Right posterior cortical functions in a tumour patient series. Cortex (2010) 3.88
Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan. J Cell Biol (2003) 2.16
Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1. J Biol Chem (2005) 2.11
The HRDC domain of BLM is required for the dissolution of double Holliday junctions. EMBO J (2005) 1.84
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol (2013) 1.67
A topological mechanism for TRF2-enhanced strand invasion. Nat Struct Mol Biol (2007) 1.65
Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A. Nucleic Acids Res (2004) 1.60
Structure of the human RECQ1 helicase reveals a putative strand-separation pin. Proc Natl Acad Sci U S A (2009) 1.52
The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities. J Biol Chem (2008) 1.52
Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression. Int J Cancer (2006) 1.50
Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation. Mol Cell Biol (2010) 1.50
Deep brain stimulation: Subthalamic nucleus electrophysiological activity in awake and anesthetized patients. Clin Neurophysiol (2012) 1.45
The role of the pathologist in tissue banking: European Consensus Expert Group Report. Virchows Arch (2010) 1.44
DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies. J Mol Biol (2002) 1.44
The experience of patients undergoing awake craniotomy: in the patients' own words. A qualitative study. Cancer Nurs (2008) 1.43
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination. J Biol Chem (2005) 1.36
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO J (2010) 1.36
Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity. PLoS Biol (2007) 1.36
Localization of proteins bound to a replication origin of human DNA along the cell cycle. EMBO J (2003) 1.33
Cobalt(II)-Nitronyl Nitroxide Chains as Molecular Magnetic Nanowires The financial support of Italian MURST and CNR and of Brazilian CNPq and FUJB is acknowledged. The support from the European Community through the TMR program 3MD (contract no ERB4061PL97-0197) is also acknowledged. Angew Chem Int Ed Engl (2001) 1.32
Pleural mesothelioma incidence in Europe: evidence of some deceleration in the increasing trends. Cancer Causes Control (2003) 1.32
O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications. Neuro Oncol (2010) 1.30
Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors. Mol Ther (2003) 1.22
RecQ helicases: multiple structures for multiple functions? HFSP J (2009) 1.20
Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK. DNA Repair (Amst) (2007) 1.19
A novel fixative improves opportunities of nucleic acids and proteomic analysis in human archive's tissues. Diagn Mol Pathol (2006) 1.18
Gait pattern in Duchenne muscular dystrophy. Gait Posture (2008) 1.16
Characterization of the DNA-unwinding activity of human RECQ1, a helicase specifically stimulated by human replication protein A. J Biol Chem (2002) 1.16
One-dimensional supramolecular organization of single-molecule magnets. J Am Chem Soc (2007) 1.11
A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation. Nucleic Acids Res (2010) 1.09
Proteomic studies on low- and high-grade human brain astrocytomas. J Proteome Res (2005) 1.06
An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63. Nat Cell Biol (2009) 1.05
Cell cycle-dependent phosphorylation of human DNA ligase I at the cyclin-dependent kinase sites. J Biol Chem (2003) 1.04
Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing. Biochemistry (2008) 1.04
Proteomic analysis of human cervical-vaginal fluids. J Proteome Res (2007) 1.04
Low-grade glioma surgery in eloquent areas: volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients: clinical article. J Neurosurg (2012) 1.03
Fluorescence anisotropy studies on the Ku-DNA interaction: anion and cation effects. J Biol Chem (2004) 1.02
Multicentre validation study of nucleic acids extraction from FFPE tissues. Virchows Arch (2010) 1.01
Prevalence of different subtypes of serrated polyps and risk of synchronous advanced colorectal neoplasia in average-risk population undergoing first-time colonoscopy. Clin Transl Gastroenterol (2012) 1.00
Effects of formalin, methacarn, and fineFIX fixatives on RNA preservation. Diagn Mol Pathol (2010) 0.99
The spiritual brain: selective cortical lesions modulate human self-transcendence. Neuron (2010) 0.98
PIK3CA in breast carcinoma: a mutational analysis of sporadic and hereditary cases. Diagn Mol Pathol (2009) 0.98
Management of stage II colon cancer - the use of molecular biomarkers for adjuvant therapy decision. BMC Gastroenterol (2013) 0.98
Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy. Clin Cancer Res (2013) 0.98
Replication stress: getting back on track. Nat Struct Mol Biol (2016) 0.97
Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas. Stem Cells (2014) 0.97
Specific impairments of rule induction in different frontal lobe subgroups. Neuropsychologia (2005) 0.97
Studies on the mode of Ku interaction with DNA. J Biol Chem (2002) 0.96
Effects of lesions to area V6A in monkeys. Exp Brain Res (2002) 0.95
Evidence of CXC, CC and C chemokine production by lymphatic endothelial cells. Immunology (2003) 0.95
Is human papillomavirus associated with prostate cancer survival? Dis Markers (2013) 0.95
Better without (lateral) frontal cortex? Insight problems solved by frontal patients. Brain (2005) 0.93
Naming manipulable objects: anatomy of a category specific effect in left temporal tumours. Neuropsychologia (2010) 0.93
Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion. Cell Cycle (2014) 0.92
Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases. Mol Med (2002) 0.92
The neural basis of temporal preparation: Insights from brain tumor patients. Neuropsychologia (2007) 0.90
Semantic access dysphasia resulting from left temporal lobe tumours. Brain (2008) 0.90
Detection of HPV E7 oncoviral protein in cervical lesions by a new antibody. Appl Immunohistochem Mol Morphol (2013) 0.90
Higher random oligo concentration improves reverse transcription yield of cDNA from bioptic tissues and quantitative RT-PCR reliability. Exp Mol Pathol (2009) 0.90
Identification of a novel motif in DNA ligases exemplified by DNA ligase IV. DNA Repair (Amst) (2006) 0.90
Bioinformatic analysis of RecQ4 helicases reveals the presence of a RQC domain and a Zn knuckle. Biophys Chem (2013) 0.89
Meditation-related activations are modulated by the practices needed to obtain it and by the expertise: an ALE meta-analysis study. Front Hum Neurosci (2013) 0.88
Cancer prevalence and mortality in centenarians: a systematic review. Crit Rev Oncol Hematol (2011) 0.88
Generation and recognition of abstract rules in different frontal lobe subgroups. Neuropsychologia (2005) 0.87
Novel target genes of PsrA transcriptional regulator of Pseudomonas aeruginosa. FEMS Microbiol Lett (2005) 0.87
Bioethics considerations for medical research in human archive tissues: the point of view of the researcher. Virchows Arch (2008) 0.87
Expression of the Polycomb-Group protein BMI1 and correlation with p16 in astrocytomas an immunohistochemical study on 80 cases. Pathol Res Pract (2008) 0.86
Causal role of the sensorimotor cortex in action simulation: neuropsychological evidence. J Cogn Neurosci (2010) 0.86
In vitro protein-DNA interactions at the human lamin B2 replication origin. J Biol Chem (2003) 0.86
A multicenter study to validate the reproducibility of MSI testing with a panel of 5 quasimonomorphic mononucleotide repeats. Diagn Mol Pathol (2010) 0.85
Surgery of insular nonenhancing gliomas: volumetric analysis of tumoral resection, clinical outcome, and survival in a consecutive series of 66 cases. Neurosurgery (2012) 0.85
Detection of spirochaetal DNA simultaneously in skin biopsies, peripheral blood and urine from patients with erythema migrans. Acta Derm Venereol (2004) 0.84
The human eosinophil proteome. Changes induced by birch pollen allergy. J Proteome Res (2009) 0.84
Delayed Positivization of Cerebral Angiography in Reversible Cerebral Vasoconstriction Syndrome (RCVS) Presenting with Recurrent Subarachnoid Haemorrhage. Open Rheumatol J (2012) 0.84
Cortical bases of elementary deductive reasoning: inference, memory, and metadeduction. Neuropsychologia (2009) 0.84
Expression of cyclin-dependent kinases and CDC25a phosphatase is related with recurrences and survival in women with peri- and post-menopausal breast cancer. Virchows Arch (2006) 0.83
Nucleic acid extraction methods from fixed and paraffin-embedded tissues in cancer diagnostics. Expert Rev Mol Diagn (2013) 0.83
Evidence of multiple infectious agents in mycosis fungoides lesions. Exp Mol Pathol (2010) 0.83
Mental rotation in a patient with an implanted electrode grid in the motor cortex. Neuroreport (2005) 0.82
HER-2 Expression in Brain Metastases from Colorectal Cancer and Corresponding Primary Tumors: A Case Cohort Series. Int J Mol Sci (2013) 0.81
Thymidilate synthase expression predicts longer survival in patients with stage II colon cancer treated with 5-flurouracil independently of microsatellite instability. J Cancer Res Clin Oncol (2010) 0.81