Published in Chem Soc Rev on July 25, 2011
5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Res (2012) 2.36
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Sci Rep (2012) 2.09
Folding and unfolding pathways of the human telomeric G-quadruplex. J Mol Biol (2014) 1.73
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat Chem (2013) 1.48
Artificial Molecular Machines. Chem Rev (2015) 1.31
G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments. Proc Natl Acad Sci U S A (2014) 1.20
Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control. Nucleic Acids Res (2013) 0.98
QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences. Nucleic Acids Res (2012) 0.97
Guanine base stacking in G-quadruplex nucleic acids. Nucleic Acids Res (2012) 0.92
C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia: gain or loss of function? Curr Opin Neurol (2014) 0.92
Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Res (2014) 0.89
G-quadruplexes for luminescent sensing and logic gates. Nucleic Acids Res (2013) 0.87
The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy. Nat Commun (2015) 0.86
Specific recognition and stabilization of monomeric and multimeric G-quadruplexes by cationic porphyrin TMPipEOPP under molecular crowding conditions. Nucleic Acids Res (2013) 0.86
QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs. Hum Genomics (2014) 0.85
Structural basis of sodium-potassium exchange of a human telomeric DNA quadruplex without topological conversion. Nucleic Acids Res (2014) 0.84
The folding of 5'-UTR human G-quadruplexes possessing a long central loop. RNA (2014) 0.84
G4LDB: a database for discovering and studying G-quadruplex ligands. Nucleic Acids Res (2012) 0.83
Stability of RNA quadruplex in open reading frame determines proteolysis of human estrogen receptor α. Nucleic Acids Res (2013) 0.82
SMMRNA: a database of small molecule modulators of RNA. Nucleic Acids Res (2013) 0.82
Directly lighting up RNA G-quadruplexes from test tubes to living human cells. Nucleic Acids Res (2015) 0.82
Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes. Nucleic Acids Res (2015) 0.81
Mechanical insights into ribosomal progression overcoming RNA G-quadruplex from periodical translation suppression in cells. Sci Rep (2016) 0.81
Isothermal folding of G-quadruplexes. Methods (2012) 0.81
The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health. J Biol Chem (2015) 0.81
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative. Nucleic Acids Res (2015) 0.81
Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system. Nucleic Acids Res (2012) 0.80
Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex. Nucleic Acids Res (2014) 0.80
HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property. Nucleic Acids Res (2014) 0.80
Looked at life from both sides now. Life (Basel) (2014) 0.78
Sugar-modified G-quadruplexes: effects of LNA-, 2'F-RNA- and 2'F-ANA-guanosine chemistries on G-quadruplex structure and stability. Nucleic Acids Res (2013) 0.78
Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches. Nucleic Acids Res (2014) 0.78
G4IPDB: A database for G-quadruplex structure forming nucleic acid interacting proteins. Sci Rep (2016) 0.78
Shape matters: size-exclusion HPLC for the study of nucleic acid structural polymorphism. Nucleic Acids Res (2014) 0.78
Discovery of a structural-element specific G-quadruplex "light-up" probe. Sci Rep (2014) 0.77
A minimal i-motif stabilized by minor groove G:T:G:T tetrads. Nucleic Acids Res (2012) 0.77
G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy. Chem Sci (2015) 0.77
Targeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+). PLoS One (2013) 0.76
Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes. Nucleic Acids Res (2015) 0.76
Identification of G-Quadruplex Inducers Usinga Simple, Inexpensiveand Rapid High Throughput Assay, and TheirInhibition of Human Telomerase. Open Med Chem J (2012) 0.76
Thioflavin T as an efficient fluorescence sensor for selective recognition of RNA G-quadruplexes. Sci Rep (2016) 0.76
Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes. J Biol Inorg Chem (2016) 0.75
Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers. Sci Rep (2016) 0.75
Synthesis and structural characterization of stable branched DNA g-quadruplexes using the trebler phosphoramidite. ChemistryOpen (2012) 0.75
A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1α. Sci Rep (2016) 0.75
Detection of G-type density in promoter sequence of colon cancer oncogenes and tumor suppressor genes. Bioinformation (2015) 0.75
Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives. PLoS One (2015) 0.75
tRNA-derived G-quadruplex protects motor neurons. Proc Natl Acad Sci U S A (2014) 0.75
Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic method. Sci Rep (2016) 0.75
Cytotoxicity of Pyrazine-Based Cyclometalated (C^N(pz)^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties. Inorg Chem (2017) 0.75
Co-existence of distinct supramolecular assemblies in solution and in the solid state. Chemistry (2016) 0.75
The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA. Int J Mol Sci (2016) 0.75
Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress. J Biol Chem (2016) 0.75
A Nucleus-Imaging Probe That Selectively Stabilizes a Minor Conformation of c-MYC G-quadruplex and Down-regulates c-MYC Transcription in Human Cancer Cells. Sci Rep (2015) 0.75
Quadruplex DNA: sequence, topology and structure. Nucleic Acids Res (2006) 6.42
Putative DNA quadruplex formation within the human c-kit oncogene. J Am Chem Soc (2005) 3.28
The structure of telomeric DNA. Curr Opin Struct Biol (2003) 2.32
Crystal structure of the potassium form of an Oxytricha nova G-quadruplex. J Mol Biol (2002) 2.29
Structure of a G-quadruplex-ligand complex. J Mol Biol (2003) 1.49
H-NS forms a superhelical protein scaffold for DNA condensation. Proc Natl Acad Sci U S A (2010) 1.30
Structural basis of DNA quadruplex recognition by an acridine drug. J Am Chem Soc (2008) 1.25
Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter. Nucleic Acids Res (2007) 1.24
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex. Nucleic Acids Res (2010) 1.16
Molecular dynamics and principal components analysis of human telomeric quadruplex multimers. Biophys J (2008) 1.16
Quadruplex DNA crystal structures and drug design. Biochimie (2008) 1.15
Out-of-shape DNA minor groove binders: induced fit interactions of heterocyclic dications with the DNA minor groove. Biochemistry (2005) 1.12
Electrospray mass spectrometry of telomeric RNA (TERRA) reveals the formation of stable multimeric G-quadruplex structures. J Am Chem Soc (2010) 1.07
Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form. J Med Chem (2003) 1.05
Structural basis of telomeric RNA quadruplex--acridine ligand recognition. J Am Chem Soc (2011) 1.03
Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures. Nucleic Acids Res (2006) 1.02
Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation. Nucleic Acids Res (2012) 1.01
Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands. J Am Chem Soc (2012) 1.01
Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography. FEBS Lett (2013) 0.98
Selectivity in ligand recognition of G-quadruplex loops. Biochemistry (2009) 0.94
Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex. J Am Chem Soc (2006) 0.93
A structural analysis of G-quadruplex/ligand interactions. Biochimie (2011) 0.92
Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes. Chem Commun (Camb) (2009) 0.91
Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes. J Med Chem (2011) 0.88
Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives. Bioorg Med Chem (2007) 0.86
Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel. J Am Chem Soc (2007) 0.86
Rational design of substituted diarylureas: a scaffold for binding to G-quadruplex motifs. J Med Chem (2008) 0.82
Structural characterization and antimicrobial evaluation of atractyloside, atractyligenin, and 15-didehydroatractyligenin methyl ester. J Nat Prod (2012) 0.80
The absence of inorganic salt is required for the crystallization of the complete oligomerization domain of Salmonella typhimurium histone-like nucleoid-structuring protein. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Targeting the DNA minor groove with fused ring dicationic compounds: comparison of in silico screening and a high-resolution crystal structure. Bioorg Med Chem Lett (2005) 0.80
Crystal structure of a promoter sequence in the B-raf gene reveals an intertwined dimer quadruplex. J Am Chem Soc (2013) 0.80
Crystallographic studies of quadruplex nucleic acids. Methods (2007) 0.80
Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization. Biochemistry (2008) 0.79