Does achieving an intensive versus usual blood pressure level prevent stroke?

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Antihypertensive treatment can prevent stroke and cognitive decline. Nat Rev Neurol (2012) 0.97

Blood pressure control and primary prevention of stroke: summary of the recent clinical trial data and meta-analyses. Curr Hypertens Rep (2013) 0.88

Lowering of blood pressure for recurrent stroke prevention. Stroke (2014) 0.81

Association between insufficient medication of antihypertensives and the severity of acute ischemic stroke. Clin Hypertens (2016) 0.78

Blood pressure and stroke prevention among people with cardiovascular disease. Ann Neurol (2012) 0.75

Hypertension up to date: SPRINT to SPYRAL. Clin Res Cardiol (2017) 0.75

Blood Pressure Management for Stroke Prevention and in Acute Stroke. J Stroke (2017) 0.75

Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2013) 14.49

Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the american heart association/american stroke association. Stroke (2010) 10.66

A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med (2013) 9.97

The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke (2007) 8.06

Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke (2005) 8.05

Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 7.48

High-thermoelectric performance of nanostructured bismuth antimony telluride bulk alloys. Science (2008) 7.34

Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N Engl J Med (2013) 7.00

Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke (2009) 6.62

Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke (2009) 5.91

2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke (2015) 5.64

Transient ischemic attack--proposal for a new definition. N Engl J Med (2002) 4.94

Comparison of MRI and CT for detection of acute intracerebral hemorrhage. JAMA (2004) 4.82

Statistical analysis of the primary outcome in acute stroke trials. Stroke (2012) 3.52

Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes. Circulation (2011) 3.30

Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100. Neurology (2012) 3.20

DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study. Lancet Neurol (2011) 3.18

Sex-specific trends in midlife coronary heart disease risk and prevalence. Arch Intern Med (2009) 3.07

Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05

Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial. Lancet Neurol (2010) 2.97

Addition of brain and carotid imaging to the ABCD² score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational study. Lancet Neurol (2010) 2.87

Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke (2003) 2.87

Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis. Ann Intern Med (2013) 2.87

Collateral flow predicts response to endovascular therapy for acute ischemic stroke. Stroke (2011) 2.80

Conscious sedation versus general anesthesia during endovascular therapy for acute anterior circulation stroke: preliminary results from a retrospective, multicenter study. Stroke (2010) 2.77

Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke (2002) 2.76

MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke (2004) 2.75

Neighborhood socioeconomic disadvantage and mortality after stroke. Neurology (2013) 2.74

Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke (2013) 2.66

Collaterals dramatically alter stroke risk in intracranial atherosclerosis. Ann Neurol (2011) 2.62

CT and MRI early vessel signs reflect clot composition in acute stroke. Stroke (2011) 2.52

Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke (2013) 2.50

Racial-ethnic disparities in stroke care: the American experience: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2011) 2.43

Low glomerular filtration rate and risk of stroke: meta-analysis. BMJ (2010) 2.42

Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity. JAMA (2012) 2.38

The smoking-thrombolysis paradox and acute ischemic stroke. Neurology (2005) 2.31

Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol (2002) 2.31

Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci (2008) 2.25

Stroke declines from third to fourth leading cause of death in the United States: historical perspective and challenges ahead. Stroke (2011) 2.23

Improving door-to-needle times in acute ischemic stroke: the design and rationale for the American Heart Association/American Stroke Association's Target: Stroke initiative. Stroke (2011) 2.19

Efficacy of intra-arterial fibrinolysis for acute ischemic stroke: meta-analysis of randomized controlled trials. Stroke (2010) 2.17

Age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke. Circulation (2010) 2.15

Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke (2003) 2.06

Effect of pre-diabetes on future risk of stroke: meta-analysis. BMJ (2012) 2.04

Indirect revascularization for nonmoyamoya intracranial arterial stenoses: clinical and angiographic outcomes. J Neurosurg (2012) 2.03

Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke. Circ Cardiovasc Qual Outcomes (2010) 2.02

Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke (2006) 2.02

Predicting clinical outcomes after thrombolysis using the iScore: results from the Virtual International Stroke Trials Archive. Stroke (2013) 2.01

Evaluation of cryptogenic stroke with advanced diagnostic techniques. Stroke (2014) 1.98

Dispatcher recognition of stroke using the National Academy Medical Priority Dispatch System. Stroke (2009) 1.96

Implementation strategies for emergency medical services within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association Expert Panel on Emergency Medical Services Systems and the Stroke Council. Stroke (2007) 1.94

Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies. Stroke (2011) 1.92

A midlife stroke surge among women in the United States. Neurology (2007) 1.86

Strategies used by hospitals to improve speed of tissue-type plasminogen activator treatment in acute ischemic stroke. Stroke (2014) 1.76

Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis. Stroke (2010) 1.75

Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale. Stroke (2009) 1.72

Simultaneous ring voice-over-Internet phone system enables rapid physician elicitation of explicit informed consent in prehospital stroke treatment trials. Cerebrovasc Dis (2009) 1.71

Expanding indications for statins in cerebral ischemia: a quantitative study. Arch Neurol (2005) 1.69

Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke (2002) 1.68

Collateral flow averts hemorrhagic transformation after endovascular therapy for acute ischemic stroke. Stroke (2011) 1.67

Risk score for in-hospital ischemic stroke mortality derived and validated within the Get With the Guidelines-Stroke Program. Circulation (2010) 1.66

Quantifying the value of stroke disability outcomes: WHO global burden of disease project disability weights for each level of the modified Rankin Scale. Stroke (2009) 1.63

Annual incidence of first silent stroke in the United States: a preliminary estimate. Cerebrovasc Dis (2003) 1.60

Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke. Stroke (2006) 1.59

Cilostazol prevents the progression of the symptomatic intracranial arterial stenosis: the multicenter double-blind placebo-controlled trial of cilostazol in symptomatic intracranial arterial stenosis. Stroke (2005) 1.58

Serial Alberta Stroke Program early CT score from baseline to 24 hours in Solitaire Flow Restoration with the Intention for Thrombectomy study: a novel surrogate end point for revascularization in acute stroke. Stroke (2014) 1.58

An original flow diversion device for the treatment of intracranial aneurysms: evaluation in the rabbit elastase-induced model. Stroke (2009) 1.56

Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Eur J Intern Med (2012) 1.55

Design and rationale of the Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE) Trial. Int J Stroke (2012) 1.55

Emergency medical service hospital prenotification is associated with improved evaluation and treatment of acute ischemic stroke. Circ Cardiovasc Qual Outcomes (2012) 1.54

Body mass index and hospital discharge outcomes after ischemic stroke. Arch Neurol (2007) 1.54

Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imaging. Ann Neurol (2007) 1.53

Declining stroke and vascular event recurrence rates in secondary prevention trials over the past 50 years and consequences for current trial design. Circulation (2011) 1.51

Relationship of national institutes of health stroke scale to 30-day mortality in medicare beneficiaries with acute ischemic stroke. J Am Heart Assoc (2012) 1.48

Acute Stroke Imaging Research Roadmap II. Stroke (2013) 1.47

Risk of intracranial hemorrhage with protease-activated receptor-1 antagonists. Stroke (2012) 1.44

Prevention and management of stroke in very elderly patients. Lancet Neurol (2009) 1.43

Multiparametric MRI and CT models of infarct core and favorable penumbral imaging patterns in acute ischemic stroke. Stroke (2012) 1.43

The new standing guideline committee policy of the American Stroke Association Stroke Council. Stroke (2006) 1.42

Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator. Stroke (2012) 1.41