Published in Stroke on May 28, 2009
The cost-effectiveness of telestroke in the treatment of acute ischemic stroke. Neurology (2011) 2.62
Matrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage. J Neurosci (2012) 1.89
Promoting axonal rewiring to improve outcome after stroke. Neurobiol Dis (2009) 1.77
Eligibility for Intravenous Recombinant Tissue-Type Plasminogen Activator Within a Population: The Effect of the European Cooperative Acute Stroke Study (ECASS) III Trial. Stroke (2012) 1.76
The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study. Stroke (2012) 1.68
A model of cost-effectiveness of tissue plasminogen activator in patient subgroups 3 to 4.5 hours after onset of acute ischemic stroke. Ann Emerg Med (2012) 1.58
The "golden hour" and acute brain ischemia: presenting features and lytic therapy in >30,000 patients arriving within 60 minutes of stroke onset. Stroke (2010) 1.50
Dissolution of arterial platelet thrombi in vivo with a bifunctional platelet GPIIIa49-66 ligand which specifically targets the platelet thrombus. Blood (2010) 1.47
Thrombolytic utilization for ischemic stroke in US hospitals with neurology residency program. Neurology (2013) 1.44
Cocktail treatment, a promising strategy to treat acute cerebral ischemic stroke? Med Gas Res (2016) 1.42
Preclinical stroke research--advantages and disadvantages of the most common rodent models of focal ischaemia. Br J Pharmacol (2011) 1.39
Cell based therapies for ischemic stroke: from basic science to bedside. Prog Neurobiol (2013) 1.39
Evolution of the thrombolytic treatment window for acute ischemic stroke. Curr Neurol Neurosci Rep (2010) 1.21
Stroke team remote evaluation using a digital observation camera in Arizona: the initial mayo clinic experience trial. Stroke (2010) 1.21
Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development. Transl Stroke Res (2010) 1.17
Recommendations for the emergency management of complications associated with the new direct oral anticoagulants (DOACs), apixaban, dabigatran and rivaroxaban. Clin Res Cardiol (2013) 1.17
Extracellular chromatin is an important mediator of ischemic stroke in mice. Arterioscler Thromb Vasc Biol (2012) 1.17
Remote supervision of IV-tPA for acute ischemic stroke by telemedicine or telephone before transfer to a regional stroke center is feasible and safe. Stroke (2009) 1.15
Provider perceptions of barriers to the emergency use of tPA for acute ischemic stroke: a qualitative study. BMC Emerg Med (2011) 1.15
Imaging-based treatment selection for intravenous and intra-arterial stroke therapies: a comprehensive review. Expert Rev Cardiovasc Ther (2011) 1.14
Glibenclamide-10-h Treatment Window in a Clinically Relevant Model of Stroke. Transl Stroke Res (2012) 1.10
Management of acute ischemic stroke. J Emerg Trauma Shock (2010) 1.07
Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia. J Cereb Blood Flow Metab (2013) 1.01
Adjunctive and alternative approaches to current reperfusion therapy. Stroke (2012) 1.00
Post-insult valproic acid-regulated microRNAs: potential targets for cerebral ischemia. Am J Transl Res (2012) 0.99
Temporal trends in acute stroke management. Stroke (2013) 0.99
Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence. J Cereb Blood Flow Metab (2011) 0.99
Intravenous Thrombolysis in Expanded Time Window (3-4.5 hours) in General Practice with Concurrent Availability of Endovascular Treatment. J Vasc Interv Neurol (2012) 0.97
Management of ischaemic stroke in the acute setting: review of the current status. Cardiovasc J Afr (2013) 0.97
Does inhibiting Sur1 complement rt-PA in cerebral ischemia? Ann N Y Acad Sci (2012) 0.96
Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models. Acta Pharmacol Sin (2011) 0.93
Interfacility helicopter ambulance transport of neurosurgical patients: observations, utilization, and outcomes from a quaternary level care hospital. PLoS One (2011) 0.93
Thrombopoietin protects the brain and improves sensorimotor functions: reduction of stroke-induced MMP-9 upregulation and blood-brain barrier injury. J Cereb Blood Flow Metab (2010) 0.92
Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells. Front Cell Neurosci (2013) 0.91
Acute stroke: a comparison of different CT perfusion algorithms and validation of ischaemic lesions by follow-up imaging. Eur Radiol (2012) 0.91
Imaging stroke patients with unclear onset times. Neuroimaging Clin N Am (2011) 0.90
Pediatric stroke: the importance of cerebral arteriopathy and vascular malformations. Childs Nerv Syst (2010) 0.90
A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke. Nanomedicine (Lond) (2011) 0.90
The role of hospitalists in the acute care of stroke patients. Curr Treat Options Cardiovasc Med (2010) 0.89
Arterial embolism. Int J Crit Illn Inj Sci (2013) 0.89
The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity. Stem Cell Res Ther (2015) 0.88
Efficacy and dose-dependent safety of intra-arterial delivery of mesenchymal stem cells in a rodent stroke model. PLoS One (2014) 0.88
Data science of stroke imaging and enlightenment of the penumbra. Front Neurol (2015) 0.87
Thrombolysis ImPlementation in Stroke (TIPS): evaluating the effectiveness of a strategy to increase the adoption of best evidence practice--protocol for a cluster randomised controlled trial in acute stroke care. Implement Sci (2014) 0.86
Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality. J Stroke Cerebrovasc Dis (2012) 0.86
Developing practice recommendations for endovascular revascularization for acute ischemic stroke. Neurology (2012) 0.86
Pitch-catch phase aberration correction of multiple isoplanatic patches for 3-D transcranial ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control (2013) 0.86
Transcranial near-infrared laser therapy applied to promote clinical recovery in acute and chronic neurodegenerative diseases. Expert Rev Med Devices (2012) 0.86
Abdominal wall hemorrhage after intravenous thrombolysis for acute ischemic stroke. BMC Neurol (2013) 0.86
Mild stroke and rapidly improving symptoms: it's not always a happy ending. Stroke (2011) 0.85
Analysis of tissue plasminogen activator eligibility by sex in the Greater Cincinnati/Northern Kentucky Stroke Study. Stroke (2015) 0.85
Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocycline. Pharmacotherapy (2010) 0.84
Estradiol modulates post-ischemic cerebral vascular remodeling and improves long-term functional outcome in a rat model of stroke. Brain Res (2012) 0.84
Racial Disparities in Intravenous Recombinant Tissue Plasminogen Activator Use Persist at Primary Stroke Centers. J Am Heart Assoc (2015) 0.84
The ultrasound brain helmet: new transducers and volume registration for in vivo simultaneous multi-transducer 3-D transcranial imaging. IEEE Trans Ultrason Ferroelectr Freq Control (2011) 0.83
Rapid Short MRI Sequence Useful in Eliminating Stroke Mimics Among Acute Stroke Patients Considered for Intravenous Thrombolysis. J Neurol Disord (2013) 0.83
Stroke damage detection using classification trees on electrical bioimpedance cerebral spectroscopy measurements. Sensors (Basel) (2013) 0.83
Assessing reperfusion with whole-brain arterial spin labeling: a noninvasive alternative to gadolinium. Stroke (2014) 0.82
A rat's whiskers point the way toward a novel stimulus-dependent, protective stroke therapy. Neuroscientist (2012) 0.82
Effectiveness of alteplase in the very elderly after acute ischemic stroke. Clin Interv Aging (2013) 0.82
Safety of thrombolysis in patients over the age of 80. Neurologist (2012) 0.82
Telemedicine in pre-hospital care: a review of telemedicine applications in the pre-hospital environment. Int J Emerg Med (2014) 0.81
Intra-arterial therapy for acute ischemic stroke. Neurotherapeutics (2011) 0.81
Intravenous thrombolytics for ischemic stroke. Neurotherapeutics (2011) 0.81
In vivo tracking of human adipose-derived stem cells labeled with ferumoxytol in rats with middle cerebral artery occlusion by magnetic resonance imaging. Neural Regen Res (2015) 0.80
A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke. PLoS One (2013) 0.80
Acceleration of tissue plasminogen activator-mediated thrombolysis by magnetically powered nanomotors. ACS Nano (2014) 0.80
Targeted Lipid Profiling Discovers Plasma Biomarkers of Acute Brain Injury. PLoS One (2015) 0.80
Antiplatelet therapy, but not intravenous thrombolytic therapy, is associated with postoperative bleeding complications after decompressive craniectomy for stroke. J Neurol (2013) 0.80
Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies. Am J Physiol Heart Circ Physiol (2014) 0.80
The epigenetics of stroke recovery and rehabilitation: from polycomb to histone deacetylases. Neurotherapeutics (2013) 0.80
Intravenous Thrombolysis for Acute Ischemic Stroke Within 3 Hours Versus Between 3 and 4.5 Hours of Symptom Onset. Neurohospitalist (2015) 0.80
Why are acute ischemic stroke patients not receiving IV tPA? Results from a national registry. Neurology (2016) 0.80
Intravenous tissue-type plasminogen activator therapy is an independent risk factor for symptomatic intracerebral hemorrhage after carotid endarterectomy. Neurosurgery (2014) 0.79
Ex-Vivo Characterization of Bioimpedance Spectroscopy of Normal, Ischemic and Hemorrhagic Rabbit Brain Tissue at Frequencies from 10 Hz to 1 MHz. Sensors (Basel) (2016) 0.79
Intra-arterial therapy for acute ischemic stroke. Interv Neurol (2013) 0.79
Management of Postthrombolysis Hemorrhagic and Orolingual Angioedema Complications. Neurohospitalist (2015) 0.78
Comparison of Therapeutic Effect of Recombinant Tissue Plasminogen Activator by Treatment Time after Onset of Acute Ischemic Stroke. Sci Rep (2015) 0.78
Regulatory T cell in stroke: a new paradigm for immune regulation. Clin Dev Immunol (2013) 0.78
Fibrinolytic therapy in acute stroke. Curr Cardiol Rev (2010) 0.78
Systematic review and stratified meta-analysis of the efficacy of carnosine in animal models of ischemic stroke. J Cereb Blood Flow Metab (2016) 0.78
Microcirculatory, mitochondrial, and histological changes following cerebral ischemia in swine. BMC Neurosci (2014) 0.78
Simultaneous bilateral real-time 3-d transcranial ultrasound imaging at 1 MHz through poor acoustic windows. Ultrasound Med Biol (2013) 0.78
Lipocalin-2 released in response to cerebral ischaemia mediates reperfusion injury in mice. J Cell Mol Med (2015) 0.78
The Role of the PI3K Pathway in the Regeneration of the Damaged Brain by Neural Stem Cells after Cerebral Infarction. J Clin Neurol (2015) 0.78
Lack of association between pretreatment neurology consultation and subsequent protocol deviation in tissue plasminogen activator-treated patients with stroke. Stroke (2010) 0.78
Using hormetic strategies to improve ischemic preconditioning and postconditioning against stroke. Int J Physiol Pathophysiol Pharmacol (2013) 0.78
Heat shock protein 90 inhibition by 17-Dimethylaminoethylamino-17-demethoxygeldanamycin protects blood-brain barrier integrity in cerebral ischemic stroke. Am J Transl Res (2015) 0.78
REACH MUSC: A Telemedicine Facilitated Network for Stroke: Initial Operational Experience. Front Neurol (2012) 0.78
What is the Role for Intra-Arterial Therapy in Acute Stroke Intervention? Neurohospitalist (2015) 0.78
Endovascular thrombectomy following acute ischemic stroke: a single-center case series and critical review of the literature. Brain Sci (2013) 0.78
Potentiating intra-arterial sonothrombolysis for acute ischemic stroke by the addition of the ultrasound contrast agents (Optison™ & SonoVue(®)). J Thromb Thrombolysis (2011) 0.77
Study on the behavioral changes of a post-stroke depression rat model. Exp Ther Med (2015) 0.77
Plasminogen activators and ischemic stroke: conditions for acute delivery. Semin Thromb Hemost (2013) 0.77
Translational MR Neuroimaging of Stroke and Recovery. Transl Stroke Res (2016) 0.77
Challenges enrolling patients with acute ischemic stroke into cell therapy trials. Stem Cells Dev (2012) 0.77
Massive pulmonary thromboembolism and stroke. Case Rep Med (2011) 0.77
Pathogenic mechanisms following ischemic stroke. Neurol Sci (2017) 0.76
Advances in medical revascularisation treatments in acute ischemic stroke. Thrombosis (2014) 0.76
Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med (1995) 47.15
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med (2008) 28.42
Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS) JAMA (1995) 13.37
Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet (2004) 12.92
Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet (2007) 10.74
Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet (2008) 4.14
Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann Neurol (1992) 3.49
Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke. Neurology (1992) 3.40
Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med (2013) 14.78
A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med (2013) 9.97
The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke (2007) 8.06
Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke (2005) 8.05
Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N Engl J Med (2013) 7.00
Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2010) 6.93
Transient ischemic attack--proposal for a new definition. N Engl J Med (2002) 4.94
Comparison of MRI and CT for detection of acute intracerebral hemorrhage. JAMA (2004) 4.82
Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 4.59
Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: the Carotid Occlusion Surgery Study randomized trial. JAMA (2011) 4.46
Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association. Stroke (2003) 4.13
Statistical analysis of the primary outcome in acute stroke trials. Stroke (2012) 3.52
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 3.48
Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke (2002) 3.43
Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev (2009) 3.40
Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes. Circulation (2011) 3.30
Methodology of the Interventional Management of Stroke III Trial. Int J Stroke (2008) 2.88
Factors influencing the decline in stroke mortality: a statement from the American Heart Association/American Stroke Association. Stroke (2013) 2.88
Addition of brain and carotid imaging to the ABCD² score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational study. Lancet Neurol (2010) 2.87
Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke (2003) 2.87
Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis. Ann Intern Med (2013) 2.87
National Stroke Association guidelines for the management of transient ischemic attacks. Ann Neurol (2006) 2.82
Collateral flow predicts response to endovascular therapy for acute ischemic stroke. Stroke (2011) 2.80
Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke (2002) 2.76
MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke (2004) 2.75
A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke (2009) 2.74
Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke (2013) 2.66
Collaterals dramatically alter stroke risk in intracranial atherosclerosis. Ann Neurol (2011) 2.62
A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes. Stroke (2012) 2.57
CT and MRI early vessel signs reflect clot composition in acute stroke. Stroke (2011) 2.52
Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke (2013) 2.50
Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 2.50
Low glomerular filtration rate and risk of stroke: meta-analysis. BMJ (2010) 2.42
Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity. JAMA (2012) 2.38
The smoking-thrombolysis paradox and acute ischemic stroke. Neurology (2005) 2.31
Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol (2002) 2.31
Recommendations for the implementation of telemedicine within stroke systems of care: a policy statement from the American Heart Association. Stroke (2009) 2.26
Stroke declines from third to fourth leading cause of death in the United States: historical perspective and challenges ahead. Stroke (2011) 2.23
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. J Cereb Blood Flow Metab (2006) 2.20
Efficacy of intra-arterial fibrinolysis for acute ischemic stroke: meta-analysis of randomized controlled trials. Stroke (2010) 2.17
Age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke. Circulation (2010) 2.15
Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke (2003) 2.06
Effect of pre-diabetes on future risk of stroke: meta-analysis. BMJ (2012) 2.04
Indirect revascularization for nonmoyamoya intracranial arterial stenoses: clinical and angiographic outcomes. J Neurosurg (2012) 2.03
Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke. Circ Cardiovasc Qual Outcomes (2010) 2.02
Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke (2006) 2.02
Dispatcher recognition of stroke using the National Academy Medical Priority Dispatch System. Stroke (2009) 1.96
A midlife stroke surge among women in the United States. Neurology (2007) 1.86
Relative edema volume is a predictor of outcome in patients with hyperacute spontaneous intracerebral hemorrhage. Stroke (2002) 1.82
Strategies used by hospitals to improve speed of tissue-type plasminogen activator treatment in acute ischemic stroke. Stroke (2014) 1.76
Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis. Stroke (2010) 1.75
Surgical results of the Carotid Occlusion Surgery Study. J Neurosurg (2012) 1.73
Simultaneous ring voice-over-Internet phone system enables rapid physician elicitation of explicit informed consent in prehospital stroke treatment trials. Cerebrovasc Dis (2009) 1.71
The types of neurological deficits might not justify withholding treatment in patients with low total National Institutes of Health Stroke Scale scores. Stroke (2012) 1.70
Expanding indications for statins in cerebral ischemia: a quantitative study. Arch Neurol (2005) 1.69
Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke (2002) 1.68
Collateral flow averts hemorrhagic transformation after endovascular therapy for acute ischemic stroke. Stroke (2011) 1.67
Risk score for in-hospital ischemic stroke mortality derived and validated within the Get With the Guidelines-Stroke Program. Circulation (2010) 1.66
Effect of antidepressants on the course of disability following stroke. Am J Geriatr Psychiatry (2011) 1.65
Quantifying the value of stroke disability outcomes: WHO global burden of disease project disability weights for each level of the modified Rankin Scale. Stroke (2009) 1.63
Part 11: adult stroke: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 1.62
Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials. Lancet Neurol (2013) 1.62
Annual incidence of first silent stroke in the United States: a preliminary estimate. Cerebrovasc Dis (2003) 1.60
Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke. Stroke (2006) 1.59
Lower stroke risk with lower blood pressure in hemodynamic cerebral ischemia. Neurology (2014) 1.59
Serum cleaved tau protein levels and clinical outcome in adult patients with closed head injury. Ann Emerg Med (2002) 1.58
Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Eur J Intern Med (2012) 1.55
Design and rationale of the Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE) Trial. Int J Stroke (2012) 1.55
Emergency medical service hospital prenotification is associated with improved evaluation and treatment of acute ischemic stroke. Circ Cardiovasc Qual Outcomes (2012) 1.54
Body mass index and hospital discharge outcomes after ischemic stroke. Arch Neurol (2007) 1.54