Published in Hum Mutat on August 11, 2011
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A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release. Retrovirology (2013) 0.84
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Counteraction of tetherin antiviral activity by two closely related SIVs differing by the presence of a Vpu gene. PLoS One (2012) 0.77
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Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions. J Virol (2013) 0.76
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No trespassing: ancient BST2 deletion confers protection against simian immunodeficiency virus infection of humans. Hum Mutat (2011) 0.75
The KT Jeang Retrovirology prize 2016: Frank Kirchhoff. Retrovirology (2016) 0.75
Efficient Vpu-mediated tetherin antagonism by an HIV-1 group O strain. J Virol (2017) 0.75
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science (2005) 14.43
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods (2004) 6.59
Semen-derived amyloid fibrils drastically enhance HIV infection. Cell (2007) 5.23
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell (2006) 4.13
Nef proteins from simian immunodeficiency viruses are tetherin antagonists. Cell Host Microbe (2009) 4.11
Neuronal or glial progeny: regional differences in radial glia fate. Neuron (2003) 3.68
Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. Cell Host Microbe (2009) 3.58
A role for glia in the progression of Rett's syndrome. Nature (2011) 3.18
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Cell Host Microbe (2012) 2.66
Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nat Med (2011) 2.65
Viscoelastic properties of individual glial cells and neurons in the CNS. Proc Natl Acad Sci U S A (2006) 2.64
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex. J Neurosci (2008) 2.49
Microglia: new roles for the synaptic stripper. Neuron (2013) 2.44
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat Med (2009) 2.41
The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol (2008) 2.38
Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J Neurosci (2003) 2.29
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. Cell (2007) 2.22
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A (2010) 2.15
Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression. Nat Med (2011) 2.08
Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer. J Virol (2009) 2.00
In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. Cell Stem Cell (2010) 1.95
Chronically CNS-injured adult sensory neurons gain regenerative competence upon a lesion of their peripheral axon. Curr Biol (2009) 1.79
Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection. J Virol (2006) 1.77
In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice. J Neurosci (2011) 1.73
Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe (2011) 1.72
Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology (2010) 1.70
NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci (2006) 1.69
Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses. J Virol (2007) 1.58
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: impact on extracellular K+ regulation. J Neurophysiol (2005) 1.57
A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells. PLoS One (2010) 1.54
Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism. J Virol (2002) 1.53
Astroglial processes show spontaneous motility at active synaptic terminals in situ. Eur J Neurosci (2004) 1.49
Seizures preferentially stimulate proliferation of radial glia-like astrocytes in the adult dentate gyrus: functional and immunocytochemical analysis. Eur J Neurosci (2003) 1.42
Expression of reef coral fluorescent proteins in the central nervous system of transgenic mice. Mol Cell Neurosci (2005) 1.42
Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2. Glia (2006) 1.42
Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol (2011) 1.42
Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). J Biol Chem (2009) 1.39
LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus. Virology (2005) 1.37
NO mediates microglial response to acute spinal cord injury under ATP control in vivo. Glia (2010) 1.36
Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease. J Neurosci (2011) 1.36
Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. J Infect Dis (2010) 1.34
Conserved residue Lys574 in the cavity of HIV-1 Gp41 coiled-coil domain is critical for six-helix bundle stability and virus entry. J Biol Chem (2007) 1.34
NMDA Receptors in glia. Neuroscientist (2007) 1.33
Nef induces multiple genes involved in cholesterol synthesis and uptake in human immunodeficiency virus type 1-infected T cells. J Virol (2005) 1.31
Tetherin: holding on and letting go. Cell (2010) 1.29
Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism. J Virol (2005) 1.29
Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes. Glia (2008) 1.28
Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue. Retrovirology (2010) 1.28
Astrocyte Ca2+ waves trigger responses in microglial cells in brain slices. FASEB J (2001) 1.27
Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication. J Biol Chem (2003) 1.25
Implications of Nef: host cell interactions in viral persistence and progression to AIDS. Curr Top Microbiol Immunol (2009) 1.24
P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes. J Neurosci (2008) 1.23
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection. PLoS Pathog (2008) 1.22
MR diffusion changes correlate with ultra-structurally defined axonal degeneration in murine optic nerve. Neuroimage (2007) 1.20
Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1. J Virol (2005) 1.20
Split-cre complementation indicates coincident activity of different genes in vivo. PLoS One (2009) 1.19
HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef. Retrovirology (2011) 1.18
Bergmann glial AMPA receptors are required for fine motor coordination. Science (2012) 1.18
Human immunodeficiency virus type 1 variants resistant to first- and second-version fusion inhibitors and cytopathic in ex vivo human lymphoid tissue. J Virol (2007) 1.14
Blind source separation techniques for the decomposition of multiply labeled fluorescence images. Biophys J (2009) 1.14
Morphology and dynamics of perisynaptic glia. Brain Res Rev (2010) 1.13
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. Nat Nanotechnol (2013) 1.12
Vpr and Vpu are important for efficient human immunodeficiency virus type 1 replication and CD4+ T-cell depletion in human lymphoid tissue ex vivo. J Virol (2004) 1.12
Comprehensive analysis of nef functions selected in simian immunodeficiency virus-infected macaques. J Virol (2004) 1.12
In Vivo imaging reveals distinct inflammatory activity of CNS microglia versus PNS macrophages in a mouse model for ALS. PLoS One (2011) 1.10
Diversity of functional astroglial properties in the respiratory network. J Neurosci (2004) 1.09
Calcium microdomains in regulated exocytosis. Cell Calcium (2006) 1.09
Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein. PLoS Pathog (2012) 1.08
The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses. J Clin Invest (2009) 1.07
Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors. AIDS (2007) 1.06
Three-dimensional confocal morphometry reveals structural changes in astrocyte morphology in situ. J Neurosci Res (2007) 1.05
Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem (2006) 1.04
Effect of R77Q, R77A and R80A changes in Vpr on HIV-1 replication and CD4 T cell depletion in human lymphoid tissue ex vivo. AIDS (2006) 1.04
Host proteins involved in HIV infection: new therapeutic targets. Biochim Biophys Acta (2009) 1.03
Normative values of polysomnographic parameters in childhood and adolescence: quantitative sleep parameters. Sleep Med (2011) 1.03
Three-dimensional confocal morphometry - a new approach for studying dynamic changes in cell morphology in brain slices. J Anat (2007) 1.03
Emerging role of the host restriction factor tetherin in viral immune sensing. J Mol Biol (2013) 1.03
T-cell receptor:CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques. J Virol (2002) 1.02
Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeys. J Virol (2010) 1.01
Enzyme identification and development of a whole-cell biotransformation for asymmetric reduction of o-chloroacetophenone. Biotechnol Bioeng (2010) 1.01
Glutamate-mediated neuronal-glial transmission. J Anat (2007) 1.01
Counteraction of HLA-C-mediated immune control of HIV-1 by Nef. J Virol (2010) 0.99
Bioactive 3D cell culture system minimizes cellular stress and maintains the in vivo-like morphological complexity of astroglial cells. Glia (2013) 0.99
Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor. J Biol Chem (2002) 0.97
Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts. J Virol (2004) 0.97
Morphological and physiological interactions of NG2-glia with astrocytes and neurons. J Anat (2007) 0.96
Bone marrow-derived cells expressing green fluorescent protein under the control of the glial fibrillary acidic protein promoter do not differentiate into astrocytes in vitro and in vivo. J Neurosci (2003) 0.96
Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation. J Clin Invest (2012) 0.95
CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry. Eur J Pharmacol (2011) 0.95
Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice. J Virol (2007) 0.93
Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques. J Virol (2006) 0.92
Selective downmodulation of HLA-A and -B by Nef alleles from different groups of primate lentiviruses. Virology (2007) 0.92
Reacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host. Cell Host Microbe (2012) 0.92
Detecting fluorescent protein expression and co-localisation on single secretory vesicles with linear spectral unmixing. Eur Biophys J (2006) 0.92