Published in Exp Cell Res on April 01, 1990
Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. J Exp Med (1990) 3.78
A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture. J Cell Biol (1991) 3.23
Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J Exp Med (1991) 3.21
The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells. EMBO J (1991) 3.20
Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons. J Cell Biol (1991) 2.57
CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway. J Exp Med (1996) 2.37
The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins. J Cell Biol (1990) 2.32
Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody. J Exp Med (1992) 2.30
CD44H regulates tumor cell migration on hyaluronate-coated substrate. J Cell Biol (1992) 2.28
Prevention of tumor metastasis formation by anti-variant CD44. J Exp Med (1993) 2.03
Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages. J Clin Invest (1993) 1.82
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth. Genes Dev (1998) 1.73
Splicing choice from ten variant exons establishes CD44 variability. Nucleic Acids Res (1993) 1.68
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Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon. J Cell Biol (1995) 1.65
The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan. J Cell Biol (1992) 1.44
The normal structure and function of CD44 and its role in neoplasia. Mol Pathol (1998) 1.44
Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronan. J Cell Biol (1998) 1.43
Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons. J Cell Biol (1995) 1.43
Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity. J Cell Biol (1996) 1.41
CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma. J Cell Biol (1996) 1.38
CD44 occupancy prevents macrophage multinucleation. J Cell Biol (1998) 1.36
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J Exp Med (1995) 1.35
Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function. J Cell Biol (1994) 1.33
The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts. J Cell Biol (1993) 1.32
Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J Cell Biol (1995) 1.31
Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition. J Cell Biol (1992) 1.27
Assembly of pericellular matrices by COS-7 cells transfected with CD44 lymphocyte-homing receptor genes. Proc Natl Acad Sci U S A (1993) 1.26
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CD44 and the adhesion of neoplastic cells. Mol Pathol (1997) 1.12
Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer. Front Immunol (2015) 1.06
A CD44-like endothelial cell transmembrane glycoprotein (GP116) interacts with extracellular matrix and ankyrin. Mol Cell Biol (1992) 1.05
A cysteine residue located in the transmembrane domain of CD44 is important in binding of CD44 to hyaluronic acid. J Exp Med (1996) 0.99
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Embryonic neurons of the developing optic chiasm express L1 and CD44, cell surface molecules with opposing effects on retinal axon growth. Neuron (1994) 0.92
Isolation and characterization of the soluble and membrane-bound porcine CD44 molecules. Immunology (1993) 0.82
CD44 and hyaluronan expression in human cutaneous scar fibroblasts. Am J Pathol (1993) 0.82
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Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proc Natl Acad Sci U S A (1989) 2.99
Complementation patterns of Thy-1 variants and evidence that antigen loss variants "pre-exist" in the parental population. J Natl Cancer Inst (1974) 2.89
Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations. Cell Immunol (1980) 2.47
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Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice. Arterioscler Thromb (1993) 1.49
Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response. J Exp Med (1994) 1.47
Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases. Mol Cell Biol (1993) 1.44
Murine cell surface transferrin receptor: studies with an anti-receptor monoclonal antibody. J Cell Physiol (1982) 1.42
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CD44 can be activated to function as an hyaluronic acid receptor in normal murine T cells. Eur J Immunol (1992) 1.37
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J Exp Med (1995) 1.35
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Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J Cell Biol (1995) 1.31
Changes in the relative abundance of type I and type II lck mRNA transcripts suggest differential promoter usage during T-cell development. Mol Cell Biol (1990) 1.29
Expression of the Thy-1 glycoprotein gene by DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1984) 1.28
Expression of transferrin receptor on murine hematopoietic progenitors. Cell Immunol (1984) 1.28
Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts. J Cell Sci (1995) 1.27
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Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor beta-chain gene. Nature (1985) 1.24
Expression of Thy-1 glycoprotein on lectin-resistant lymphoma cell lines. Eur J Immunol (1978) 1.22
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Two complementation classes of T200 (Ly-5) glycoprotein-negative mutants. Immunogenetics (1981) 1.18
Studies on surface antigen variants. Isolation of two complementary variants for Thy 1.2. J Natl Cancer Inst (1973) 1.16
CD44 in inflammation and metastasis. Glycoconj J (1997) 1.16
Evidence that the Pgp-1 glycoprotein is expressed on thymus-homing progenitor cells of the thymus. Cell Immunol (1985) 1.15
The two-dimensional topographic distribution of H-2 histocompatibility alloantigens on mouse red blood cell membranes. J Cell Biol (1971) 1.14
Antibody-induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody. Eur J Immunol (1993) 1.13
Role of CD44 cytoplasmic domain in hyaluronan binding. Eur J Immunol (1995) 1.11
Somatic genetic analysis of the expression of cell surface molecules. Trends Genet (1988) 1.11
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Cell-surface-antigen mutants of haematopoietic cells. Tools to study differentiation, biosynthesis and function. Biochem J (1985) 1.05
Macrophages and T cells do not express Mlsa determinants. J Immunol (1989) 1.05
Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding. Cancer Res (1998) 1.05
Modulation of transferrin receptor expression and function by anti-transferrin receptor antibodies and antibody fragments. Exp Cell Res (1989) 1.04
Somatic cell mutants distinguish CD44 expression and hyaluronic acid binding. Immunogenetics (1991) 1.04
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Ambiguous role of interleukin-12 in Yersinia enterocolitica infection in susceptible and resistant mouse strains. Infect Immun (1998) 1.01
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A rabbit antiserum to a thymus extract specific for mouse thymus-derived cells. J Immunol (1973) 0.92
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The role of the CD44 cytoplasmic and transmembrane domains in constitutive and inducible hyaluronan binding. Eur J Immunol (2000) 0.91
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Aldosterone-mediated regulation of Na+, K(+)-ATPase gene expression in adult and neonatal rat cardiocytes. J Biol Chem (1991) 0.83
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A mutant lymphoma cell line with a defective Thy-1 glycoprotein gene. Immunogenetics (1987) 0.82
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