Published in Eur J Immunol on October 01, 1992
Hyaluronan as an immune regulator in human diseases. Physiol Rev (2011) 2.74
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CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway. J Exp Med (1996) 2.37
Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages. J Clin Invest (1993) 1.82
Hyaluronan-CD44 interactions as potential targets for cancer therapy. FEBS J (2011) 1.63
T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J Exp Med (1994) 1.55
Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response. J Exp Med (1994) 1.47
The normal structure and function of CD44 and its role in neoplasia. Mol Pathol (1998) 1.44
Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons. J Cell Biol (1995) 1.43
Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity. J Cell Biol (1996) 1.41
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J Exp Med (1995) 1.35
Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J Cell Biol (1995) 1.31
Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan. J Cell Biol (1996) 1.31
Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44. Blood (2005) 1.19
Forms and functions of CD44. Immunology (1998) 1.15
The hyaluronic acid receptor CD44 coordinates normal and metaplastic gastric epithelial progenitor cell proliferation. J Biol Chem (2013) 1.14
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Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer. Front Immunol (2015) 1.06
Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism. J Virol (1995) 1.05
Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain. J Exp Med (1995) 0.97
Delivery of CD44 shRNA/nanoparticles within cancer cells: perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE. J Biol Chem (2009) 0.93
Targeted disruption of CD44 in MDAY-D2 lymphosarcoma cells has no effect on subcutaneous growth or metastatic capacity. J Cell Biol (1995) 0.90
Membrane localization of membrane type 1 matrix metalloproteinase by CD44 regulates the activation of pro-matrix metalloproteinase 9 in osteoclasts. Biomed Res Int (2013) 0.85
Lipid-Based Nanovectors for Targeting of CD44-Overexpressing Tumor Cells. J Drug Deliv (2013) 0.85
Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization. J Biol Chem (2016) 0.84
The Role of Hyaluronan and CD44 in the Pathogenesis of Lupus Nephritis. Autoimmune Dis (2012) 0.83
Selective killing of breast cancer cells expressing activated CD44 using CD44 ligand-coated nanoparticles in vitro and in vivo. Oncotarget (2015) 0.80
Growth as a solid tumor or reduced glucose concentrations in culture reversibly induce CD44-mediated hyaluronan recognition by Chinese hamster ovary cells. J Clin Invest (1997) 0.80
Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer. Med Chem Res (2014) 0.80
Terminal sialic acids on CD44 N-glycans can block hyaluronan binding by forming competing intramolecular contacts with arginine sidechains. Proteins (2014) 0.79
Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells. Bioorg Med Chem (2013) 0.78
The expression of CD44 in archival paraffin embedded interface tissues of failed orthopaedic implants. J Mater Sci Mater Med (2004) 0.78
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis. PLoS One (2013) 0.76
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Hydrolysis of Hyaluronic Acid in Lymphedematous Tissue Alleviates Fibrogenesis via TH1 Cell-Mediated Cytokine Expression. Sci Rep (2017) 0.75
TGF beta-1 induced CD44v6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis. J Biol Chem (2017) 0.75
CD44 and its interaction with extracellular matrix. Adv Immunol (1993) 4.04
Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues. Immunogenetics (1982) 3.18
Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proc Natl Acad Sci U S A (1989) 2.99
Complementation patterns of Thy-1 variants and evidence that antigen loss variants "pre-exist" in the parental population. J Natl Cancer Inst (1974) 2.89
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Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody. J Exp Med (1992) 2.30
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility. Nat Genet (2000) 2.18
Binding of hyaluronic acid to lymphoid cell lines is inhibited by monoclonal antibodies against Pgp-1. Exp Cell Res (1990) 1.90
Hyaluronan binding by cell surface CD44. J Biol Chem (2000) 1.86
Thymidine kinase obliteration: creation of transgenic mice with controlled immune deficiency. Proc Natl Acad Sci U S A (1989) 1.74
Identification and characterization of the human Pgp-1 glycoprotein. Immunogenetics (1986) 1.69
The synthesis and properties of T25 blycoprotein in Thy-1-negative mutant lymphoma cells. Cell (1978) 1.59
Adding value to clinical data by linkage to a public death registry. Stud Health Technol Inform (2001) 1.59
Cell-specific antigens and immunoglobulin synthesis of murine myeloma cells and their variants. J Natl Cancer Inst (1972) 1.55
Structure of the lipid-linked oligosaccharides that accumulate in class E Thy-1-negative mutant lymphomas. Cell (1979) 1.52
Participation of histocompatibility antigens in capping of molecularly independent cell surface components by their specific antibodies. Proc Natl Acad Sci U S A (1978) 1.51
Anchoring of membrane proteins via phosphatidylinositol is deficient in two classes of Thy-1 negative mutant lymphoma cells. EMBO J (1986) 1.49
Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice. Arterioscler Thromb (1993) 1.49
Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response. J Exp Med (1994) 1.47
Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases. Mol Cell Biol (1993) 1.44
Identification of defects in glycosylphosphatidylinositol anchor biosynthesis in the Thy-1 expression mutants. J Biol Chem (1991) 1.41
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J Exp Med (1995) 1.35
Analysis of lymphocyte surface antigen expression by the use of variant cell lines. Cold Spring Harb Symp Quant Biol (1977) 1.33
Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J Cell Biol (1995) 1.31
Changes in the relative abundance of type I and type II lck mRNA transcripts suggest differential promoter usage during T-cell development. Mol Cell Biol (1990) 1.29
Expression of transferrin receptor on murine hematopoietic progenitors. Cell Immunol (1984) 1.28
Expression of the Thy-1 glycoprotein gene by DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1984) 1.28
Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts. J Cell Sci (1995) 1.27
Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition. J Cell Biol (1992) 1.27
Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor beta-chain gene. Nature (1985) 1.24
Expression of Thy-1 glycoprotein on lectin-resistant lymphoma cell lines. Eur J Immunol (1978) 1.22
Thy-1 variants of mouse lymphomas: biochemical characterization of the genetic defect. Cell (1975) 1.20
No glycolipid anchors are added to Thy-1 glycoprotein in Thy-1-negative mutant thymoma cells of four different complementation classes. Mol Cell Biol (1988) 1.19
CD44 structure and function. Front Biosci (1998) 1.18
Two complementation classes of T200 (Ly-5) glycoprotein-negative mutants. Immunogenetics (1981) 1.18
CD44 in inflammation and metastasis. Glycoconj J (1997) 1.16
Studies on surface antigen variants. Isolation of two complementary variants for Thy 1.2. J Natl Cancer Inst (1973) 1.16
Evidence that the Pgp-1 glycoprotein is expressed on thymus-homing progenitor cells of the thymus. Cell Immunol (1985) 1.15
The two-dimensional topographic distribution of H-2 histocompatibility alloantigens on mouse red blood cell membranes. J Cell Biol (1971) 1.14
Antibody-induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody. Eur J Immunol (1993) 1.13
Role of CD44 cytoplasmic domain in hyaluronan binding. Eur J Immunol (1995) 1.11
Somatic genetic analysis of the expression of cell surface molecules. Trends Genet (1988) 1.11
Abnormal lipid-linked oligosaccharides in class E Thy-1-negative mutant lymphomas. Cell (1979) 1.11
Natural autoantibodies to thymocytes: origin, VH genes, fine specificities, and the role of Thy-1 glycoprotein. J Exp Med (1990) 1.09
Progenitor cells in the thymus: most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface. Cell Immunol (1986) 1.06
Effect of antigen density on complement-mediated lysis, T-cell-mediated killing, and antigenic modulation. J Natl Cancer Inst (1974) 1.06
Macrophages and T cells do not express Mlsa determinants. J Immunol (1989) 1.05
Cell-surface-antigen mutants of haematopoietic cells. Tools to study differentiation, biosynthesis and function. Biochem J (1985) 1.05
Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding. Cancer Res (1998) 1.05
Derivation of lymphoma variants with reduced sensitivity to plant lectins. J Natl Cancer Inst (1974) 1.03
Surface molecules of cultured human lymphoid cells. Eur J Immunol (1976) 1.01
The importance of serologically detectable histocompatibility antigens in the induction and effector step of cell-mediated lysis. Eur J Immunol (1977) 0.98
A new murine model system for the in vitro development of thymoma cell heterogeneity. Cancer Res (1984) 0.96
A mutational hot-spot within an intron of the mouse beta 2-microglobulin gene. EMBO J (1986) 0.95
Evidence that murine hematopoietic cell subset marker J11d is attached to a glycosyl-phosphatidylinositol membrane anchor. Eur J Immunol (1987) 0.94
Qualitative and quantitative heterogeneity in Pgp-1 expression among murine thymocytes. Cell Immunol (1988) 0.93
The Pgp-1 antigen is expressed on early fetal thymocytes. Immunogenetics (1985) 0.93
Non-tumoural aqueduct stenosis and normal pressure hydrocephalus in the elderly. J Neurol Neurosurg Psychiatry (1986) 0.93
Effect of gene dosage on cell-surface expression of Thy-1 antigen in somatic cell hybrids between Thy-1- Abelson-leukemia-virus induced lymphomas and Thy-1+ mouse lymphomas. Immunogenetics (1981) 0.92
A rabbit antiserum to a thymus extract specific for mouse thymus-derived cells. J Immunol (1973) 0.92
The role of the CD44 cytoplasmic and transmembrane domains in constitutive and inducible hyaluronan binding. Eur J Immunol (2000) 0.91
Human B cell line deficient in the expression of B cell-specific glycoproteins (GP 27,35). Eur J Immunol (1977) 0.91
Antibody-induced changes in expression of the H-2 antigen. Eur J Immunol (1974) 0.90
Cell surface molecules of Friend erythroleukemias: decrease in T200 glycoprotein expression after induction. J Cell Physiol (1980) 0.90
Functional Thy-1+ cells in cultures of spleen cells from nu/nu mice. Eur J Immunol (1980) 0.90
Simple reaction times of ipsilateral and contralateral hand to lateralized visual stimuli. Brain (1971) 0.89
Analysis of commitment of human leukemia HL-60 cells to terminal granulocytic maturation. Cancer Res (1985) 0.89
Genetic basis for Ly-6- defect: complementation between Ly-6- and Thy-1- mutant cell lines. Immunogenetics (1983) 0.89
Contribution of de-novo and salvage synthesis to the uracil nucleotide pool in mouse tissues and tumors in vivo. Eur J Biochem (1992) 0.85
Revertant expressing a structural variant of T200 glycoprotein. Immunogenetics (1982) 0.85
Dynamics of toxin and lectin receptors on a lymphoma cell line and its toxin-resistant variant using ferritin-conjugated, 125I-labeled ligand. J Cell Biol (1978) 0.84
Aldosterone-mediated regulation of Na+, K(+)-ATPase gene expression in adult and neonatal rat cardiocytes. J Biol Chem (1991) 0.83
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Stable expression of the mouse lymphocyte T200 antigen in L-cells after transfection with lymphoma DNA. Mol Immunol (1985) 0.82
A mutant lymphoma cell line with a defective Thy-1 glycoprotein gene. Immunogenetics (1987) 0.82
Immunoelectron microscopic localization of Thy-1 glycoprotein in wild type and Thy-1-negative lymphoma cells. Cell Biol Int Rep (1982) 0.81
Cell-surface changes in Ricinus communis toxin (ricin)-resistant variant of a murine lymphoma. J Natl Cancer Inst (1977) 0.81
Phenotypic analysis of the early events during repopulation of the thymus by the bone marrow prothymocyte. Cell Immunol (1990) 0.80
Acute retinal necrosis syndrome presenting with papillitis and arcuate neuroretinitis. Ophthalmology (1988) 0.80
Antibody-induced changes in expression of an immunoglobulin surface antigen. Eur J Immunol (1973) 0.80
CD44 and other cell interaction molecules contributing to B lymphopoiesis. Curr Top Microbiol Immunol (1993) 0.79
Kinetics of thymus repopulation by intrathymic progenitors after intravenous injection: evidence for successive repopulation by an IL-2R+, Pgp-1- and by an IL-2R-, Pgp-1+ progenitor. Cell Immunol (1988) 0.79
Divergence paralysis as the initial sign in the Miller Fisher syndrome. Am J Ophthalmol (1986) 0.79
Cell surface receptors and their dynamics on toxin-treated malignant cells. J Supramol Struct (1976) 0.79
Autocrine growth and progression of murine X-ray-induced T cell lymphomas. EMBO J (1986) 0.79
Tcl-30, a new T cell-specific gene expressed in immature glucocorticoid-sensitive thymocytes. J Immunol (1992) 0.79
Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform. J Biol Chem (1991) 0.78
Correlated expression of a B-lymphocyte-specific glycoprotein (gp27/35) and the EBV receptor/C3 receptor complex in sublines from the same Burkitt lymphoma. Int J Cancer (1979) 0.78
Adhesion of lymphoid cells to CD44-specific substrata: the consequences of attachment depend on the ligand. Exp Cell Res (2000) 0.77
Regulation of Thy-1 and Pgp-1 glycoproteins in hybrids between T-cell lymphomas and Abelson-leukemia-virus-induced lymphomas. Immunogenetics (1984) 0.76
Absence of Thy-1 antigen in L-cell X mouse lymphoma hybrids. Somatic Cell Genet (1975) 0.76
The effect of nuclear magnetic resonance imaging on metallic middle ear prostheses. Otolaryngol Head Neck Surg (1986) 0.75
Simultaneous occurrence of herniated disc and mesothelial cyst in a 16-year-old male. Childs Nerv Syst (1986) 0.75
Genetic alterations in tumor cells resulting in their escape from the immune response. Cancer Chemother Rep (1974) 0.75
Failure to diagnose conus ependymomas by magnetic resonance imaging. Spine (Phila Pa 1976) (1989) 0.75
[Clinical and neuropsychological characteristics of normal pressure hydrocephalus]. Ned Tijdschr Geneeskd (1987) 0.75
A Thy-1- mutant defining a gene acting in trans position to regulate cell-surface Thy-1 glycoprotein expression and Thy-1 messenger RNA content. Immunogenetics (1986) 0.75