Published in J Ocul Biol Dis Infor on July 28, 2010
Mechanism of inflammation in age-related macular degeneration. Mediators Inflamm (2012) 1.14
Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis. PLoS One (2012) 0.94
Pharmacogenetic associations with long-term response to anti-vascular endothelial growth factor treatment in neovascular AMD patients. Mol Vis (2014) 0.85
A pharmacogenetics study to predict outcome in patients receiving anti-VEGF therapy in age related macular degeneration. Clin Ophthalmol (2013) 0.81
Vascular endothelial growth factor genetic polymorphisms and susceptibility to age-related macular degeneration in Tunisian population. Biomark Res (2014) 0.80
Association of PEDF polymorphisms with age-related macular degeneration and polypoidal choroidal vasculopathy: a systematic review and meta-analysis. Sci Rep (2015) 0.78
Predictors of visual response to intravitreal bevacizumab for treatment of neovascular age-related macular degeneration. J Ophthalmol (2013) 0.76
Vascular endothelial growth factor gene polymorphisms and association with age related macular degeneration in Indian patients. Meta Gene (2016) 0.75
Bevacizumab treatment for neovascular age-related macular degeneration in the setting of a clinic: "real life" long-term outcome. BMC Ophthalmol (2015) 0.75
A Validated Phenotyping Algorithm for Genetic Association Studies in Age-related Macular Degeneration. Sci Rep (2015) 0.75
Prognostic phenotypic and genotypic factors associated with photodynamic therapy response in patients with age-related macular degeneration. Clin Ophthalmol (2014) 0.75
Complement factor H polymorphism in age-related macular degeneration. Science (2005) 31.10
Ranibizumab for neovascular age-related macular degeneration. N Engl J Med (2006) 30.63
Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med (1995) 26.60
Complement factor H variant increases the risk of age-related macular degeneration. Science (2005) 17.95
Vascular endothelial growth factor is a secreted angiogenic mitogen. Science (1989) 16.71
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A (2005) 13.44
Pegaptanib for neovascular age-related macular degeneration. N Engl J Med (2004) 12.01
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet (2006) 7.49
Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging (2005) 7.31
HTRA1 promoter polymorphism in wet age-related macular degeneration. Science (2006) 7.12
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet (2005) 6.36
The epidemiology of age-related macular degeneration. Am J Ophthalmol (2004) 5.86
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science (2006) 5.67
Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science (1999) 5.53
Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study Report Number 3. Ophthalmology (2000) 5.18
Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet (2005) 4.91
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet (2006) 4.51
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet (2003) 4.19
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet (2008) 4.16
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A (2007) 3.50
Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology (2005) 3.28
Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Arch Ophthalmol (2003) 3.17
Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. Am J Hum Genet (2006) 2.89
Clinical characteristics of exudative age-related macular degeneration in Japanese patients. Am J Ophthalmol (2007) 2.53
A common polymorphism in the 5'-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes. Diabetes (2002) 2.46
Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab. Ophthalmology (2007) 1.96
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. J Cell Physiol (2001) 1.94
Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration. Exp Eye Res (2005) 1.84
Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6. Invest Ophthalmol Vis Sci (2006) 1.60
VEGF polymorphisms are associated with neovascular age-related macular degeneration. Hum Mol Genet (2006) 1.57
Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF. J Cell Physiol (2001) 1.56
Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab. Br J Ophthalmol (2008) 1.47
Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy. Am J Ophthalmol (2002) 1.40
Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population. Ophthalmology (2010) 1.26
Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications for novel therapies. Ophthalmic Res (1997) 1.24
Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. Am J Ophthalmol (2002) 1.24
Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes. Biochem Biophys Res Commun (2005) 1.19
Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci (2002) 1.16
The role of vascular endothelial growth factor genetic variability in cancer. Clin Cancer Res (2009) 1.13
Photodynamic therapy in macular diseases of asian populations: when East meets West. Jpn J Ophthalmol (2006) 1.01
Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration. Ophthalmology (2010) 1.01
Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study. Ophthalmology (2008) 0.99
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature (2007) 8.87
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe (2009) 5.12
Buonocore memorial lecture. Adhesion to enamel and dentin: current status and future challenges. Oper Dent (2003) 4.75
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet (2003) 4.19
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol (2009) 3.58
Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth. Nature (2002) 2.32
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev (2012) 2.10
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
Inhibition of brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release [corrected]. Proc Natl Acad Sci U S A (2010) 2.05
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci (2002) 2.03
Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5. Sci Signal (2011) 1.88
Homozygosity haplotype allows a genomewide search for the autosomal segments shared among patients. Am J Hum Genet (2007) 1.76
Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res (2002) 1.69
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem (2003) 1.69
Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. J Clin Endocrinol Metab (2007) 1.57
A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferons. Biochem Biophys Res Commun (2005) 1.54
Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations. Am J Med Genet A (2006) 1.54
De novo formation and rupture of an aneurysm. Case report. J Neurosurg (2002) 1.52
Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. EMBO J (2013) 1.48
TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev (2012) 1.45
Olanzapine-induced delirium in a terminally ill cancer patient. J Pain Symptom Manage (2004) 1.45
GPR98/Gpr98 gene is involved in the regulation of human and mouse bone mineral density. J Clin Endocrinol Metab (2012) 1.44
Increased plasma morphine metabolites in terminally ill cancer patients with delirium: an intra-individual comparison. J Pain Symptom Manage (2002) 1.44
Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population. Nat Genet (2011) 1.43
Genome-wide single nucleotide polymorphism typing method for identification of Bacillus anthracis species and strains among B. cereus group species. J Clin Microbiol (2010) 1.38
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). Int J Oncol (2007) 1.34
Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem (2006) 1.33
Targeted gene expression using the GAL4/UAS system in the silkworm Bombyx mori. Genetics (2003) 1.31
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival. J Exp Med (2013) 1.30
Technique-sensitivity of contemporary adhesives. Dent Mater J (2005) 1.30
A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle. Nat Commun (2013) 1.29
A simple and rapid immunochromatographic test kit for rabies diagnosis. Microbiol Immunol (2008) 1.27
Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population. Ophthalmology (2010) 1.26
Nuclear cyclin B1 in human breast carcinoma as a potent prognostic factor. Cancer Sci (2007) 1.24
Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries. J Biomed Opt (2012) 1.21
Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth. Cancer Res (2009) 1.20
Quantitative assessment of the integrity of the blood-retinal barrier in mice. Invest Ophthalmol Vis Sci (2002) 1.20
17Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells. J Biol Chem (2006) 1.20
Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes. Biochem Biophys Res Commun (2005) 1.19
Survival versus apoptotic 17beta-estradiol effect: role of ER alpha and ER beta activated non-genomic signaling. J Cell Physiol (2005) 1.18
Estrogen receptors and their downstream targets in cancer. Arch Histol Cytol (2004) 1.18
Estrogen receptor-associated expression of keratinocyte growth factor and its possible role in the inhibition of apoptosis in human breast cancer. Lab Invest (2004) 1.17
The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan. J Clin Endocrinol Metab (2005) 1.17
[Retinal thickness and changes with age]. Nippon Ganka Gakkai Zasshi (2002) 1.17
Topical nepafenac inhibits ocular neovascularization. Invest Ophthalmol Vis Sci (2003) 1.16
Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation. Clin Cancer Res (2004) 1.16
The activity of bisphenol A depends on both the estrogen receptor subtype and the cell type. Endocr J (2002) 1.15
TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancer. Mol Endocrinol (2012) 1.15
CLOCK/BMAL1 is involved in lipid metabolism via transactivation of the peroxisome proliferator-activated receptor (PPAR) response element. J Atheroscler Thromb (2005) 1.15
Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid). Pharm Res (2010) 1.13
Coding and noncoding variants in the CFH gene and cigarette smoking influence the risk of age-related macular degeneration in a Japanese population. Invest Ophthalmol Vis Sci (2007) 1.13
Effect of water storage on the bonding effectiveness of 6 adhesives to Class I cavity dentin. Oper Dent (2006) 1.13
Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway. Hum Gene Ther (2002) 1.12
Efficient gene transfer via retrograde transport in rodent and primate brains using a human immunodeficiency virus type 1-based vector pseudotyped with rabies virus glycoprotein. Hum Gene Ther (2007) 1.12
Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes. Diabetes Care (2004) 1.12
Active tremor cancellation by a "smart" handheld vitreoretinal microsurgical tool using swept source optical coherence tomography. Opt Express (2012) 1.12
Runx2 in human breast carcinoma: its potential roles in cancer progression. Cancer Sci (2010) 1.11
Identification and Herc5-mediated ISGylation of novel target proteins. Biochem Biophys Res Commun (2006) 1.10
Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma. Oncogene (2005) 1.10
Effect of cavity configuration and aging on the bonding effectiveness of six adhesives to dentin. Dent Mater (2005) 1.09
Rabies virus stimulates nitric oxide production and CXC chemokine ligand 10 expression in macrophages through activation of extracellular signal-regulated kinases 1 and 2. J Virol (2004) 1.09
Effect of evaporation of primer components on ultimate tensile strengths of primer-adhesive mixture. Dent Mater (2005) 1.08
Implantation of rectal cancer in an anal fistula: report of a case. Surg Today (2006) 1.07
A highly attenuated rabies virus HEP-Flury strain reverts to virulent by single amino acid substitution to arginine at position 333 in glycoprotein. Virus Res (2006) 1.06
Comparison of epiretinal membranes of differing pathogenesis using optical coherence tomography. Retina (2004) 1.06
A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain. Nat Commun (2010) 1.05
Epigenetic and proteolytic inactivation of 14-3-3sigma in breast and prostate cancers. Semin Cancer Biol (2006) 1.05
Four-year water degradation of a resin-modified glass-ionomer adhesive bonded to dentin. Eur J Oral Sci (2004) 1.04
Efficacy of oral E1210, a new broad-spectrum antifungal with a novel mechanism of action, in murine models of candidiasis, aspergillosis, and fusariosis. Antimicrob Agents Chemother (2011) 1.04
The shortage of pediatrician workforce in rural areas of Japan. Tohoku J Exp Med (2009) 1.03
Retinal neuroprotection against ischemic injury mediated by intraocular gene transfer of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci (2003) 1.03
Nitric oxide is proangiogenic in the retina and choroid. J Cell Physiol (2002) 1.03
Cellular delivery of doxorubicin via pH-controlled hydrazone linkage using multifunctional nano vehicle based on poly(β-l-malic acid). Int J Mol Sci (2012) 1.02
MiR-424/503-mediated Rictor upregulation promotes tumor progression. PLoS One (2013) 1.02
LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells. Biochem Biophys Res Commun (2006) 1.02
Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration. Ophthalmology (2010) 1.01
Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population. J Hum Genet (2007) 1.01