Published in Proc Natl Acad Sci U S A on September 06, 2011
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Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature (2008) 2.54
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Principles of microRNA-target recognition. PLoS Biol (2005) 23.70
bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell (2003) 22.14
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
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The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science (2002) 11.11
Ribo-gnome: the big world of small RNAs. Science (2005) 10.10
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res (2007) 9.61
RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo. Nat Genet (2007) 9.56
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev (2006) 8.78
A high-resolution map of human evolutionary constraint using 29 mammals. Nature (2011) 8.67
Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome. Proc Natl Acad Sci U S A (2002) 8.56
An endogenous small interfering RNA pathway in Drosophila. Nature (2008) 7.88
A protein sensor for siRNA asymmetry. Science (2004) 7.77
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell (2002) 6.43
Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell (2009) 6.39
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
An epigenetic role for maternally inherited piRNAs in transposon silencing. Science (2008) 5.05
Reliable prediction of regulator targets using 12 Drosophila genomes. Genome Res (2007) 4.89
RISC assembly defects in the Drosophila RNAi mutant armitage. Cell (2004) 4.88
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo. Genes Dev (2007) 4.59
Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo. Cell (2002) 4.00
Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Mol Cell Biol (2006) 3.80
Synchronous and stochastic patterns of gene activation in the Drosophila embryo. Science (2009) 3.58
Systematic discovery of new recognition peptides mediating protein interaction networks. PLoS Biol (2005) 3.28
The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse. Dev Cell (2013) 3.14
Genome-wide quantitative enhancer activity maps identified by STARR-seq. Science (2013) 3.11
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The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
Characterization of the intergenic RNA profile at abdominal-A and Abdominal-B in the Drosophila bithorax complex. Proc Natl Acad Sci U S A (2002) 2.94
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell (2011) 2.69
Regulatory blueprint for a chordate embryo. Science (2006) 2.67
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat Struct Mol Biol (2009) 2.64
Shadow enhancers foster robustness of Drosophila gastrulation. Curr Biol (2010) 2.63
The relationship between sequence and interaction divergence in proteins. J Mol Biol (2003) 2.59
Immunity regulatory DNAs share common organizational features in Drosophila. Mol Cell (2004) 2.58
The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer. Science (2010) 2.53
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A regulatory code for neurogenic gene expression in the Drosophila embryo. Development (2004) 2.41
Denoising feedback loops by thresholding--a new role for microRNAs. Genes Dev (2006) 2.37
miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data. Genome Biol (2010) 2.18
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High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species. Nat Genet (2011) 1.94
A distinct class of small RNAs arises from pre-miRNA-proximal regions in a simple chordate. Nat Struct Mol Biol (2009) 1.90
Coordinate enhancers share common organizational features in the Drosophila genome. Proc Natl Acad Sci U S A (2004) 1.90
Multiple enhancers ensure precision of gap gene-expression patterns in the Drosophila embryo. Proc Natl Acad Sci U S A (2011) 1.80
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Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Nature (2010) 1.77
Predictions without templates: new folds, secondary structure, and contacts in CASP5. Proteins (2003) 1.76
Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex. Proc Natl Acad Sci U S A (2002) 1.74
pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos. Genes Dev (2004) 1.73
Ciona intestinalis: an emerging model for whole-genome analyses. Trends Genet (2003) 1.69
Quantitative analysis of binding motifs mediating diverse spatial readouts of the Dorsal gradient in the Drosophila embryo. Proc Natl Acad Sci U S A (2005) 1.67
Clusters of temporal discordances reveal distinct embryonic patterning mechanisms in Drosophila and anopheles. PLoS Biol (2011) 1.65
The snail repressor inhibits release, not elongation, of paused Pol II in the Drosophila embryo. Curr Biol (2011) 1.63
A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J (2011) 1.58
Regulation of Hox gene activity by transcriptional elongation in Drosophila. Curr Biol (2009) 1.55
Stalled Hox promoters as chromosomal boundaries. Genes Dev (2009) 1.55
A simplified miRNA-based gene silencing method for Drosophila melanogaster. Dev Biol (2008) 1.54
HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature. Genes Dev (2012) 1.53
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Accurate prediction of peptide binding sites on protein surfaces. PLoS Comput Biol (2009) 1.48
A computational pipeline for comparative ChIP-seq analyses. Nat Protoc (2011) 1.42
A dynamic structural model for estrogen receptor-alpha activation by ligands, emphasizing the role of interactions between distant A and E domains. Mol Cell (2002) 1.40
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Genome-wide identification of tissue-specific enhancers in the Ciona tadpole. Proc Natl Acad Sci U S A (2002) 1.36
Evolutionary origins of the vertebrate heart: Specification of the cardiac lineage in Ciona intestinalis. Proc Natl Acad Sci U S A (2003) 1.34
Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding. Genome Res (2012) 1.34
The transcription/migration interface in heart precursors of Ciona intestinalis. Science (2008) 1.32
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Long-range enhancer-promoter interactions in the Scr-Antp interval of the Drosophila Antennapedia complex. Proc Natl Acad Sci U S A (2003) 1.30
Uncoupling heart cell specification and migration in the simple chordate Ciona intestinalis. Development (2005) 1.27
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Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene. Nat Neurosci (2011) 1.26
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Localized repressors delineate the neurogenic ectoderm in the early Drosophila embryo. Dev Biol (2005) 1.23
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Ventral dominance governs sequential patterns of gene expression across the dorsal-ventral axis of the neuroectoderm in the Drosophila embryo. Dev Biol (2003) 1.19
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A genomewide survey of developmentally relevant genes in Ciona intestinalis. I. Genes for bHLH transcription factors. Dev Genes Evol (2003) 1.18
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ELAV mediates 3' UTR extension in the Drosophila nervous system. Genes Dev (2012) 1.16
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Precision of hunchback expression in the Drosophila embryo. Curr Biol (2012) 1.14
Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system. Development (2008) 1.12
Transcription factor binding site identification using the self-organizing map. Bioinformatics (2005) 1.11
A genomewide survey of developmentally relevant genes in Ciona intestinalis. II. Genes for homeobox transcription factors. Dev Genes Evol (2003) 1.11
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