Long-range enhancer-promoter interactions in the Scr-Antp interval of the Drosophila Antennapedia complex.

PubWeight™: 1.30‹?› | Rank: Top 10%

🔗 View Article (PMC 187872)

Published in Proc Natl Acad Sci U S A on August 08, 2003

Authors

Vincent C Calhoun1, Michael Levine

Author Affiliations

1: Department of Molecular and Cell Biology, Division of Genetics and Development, University of California, Berkeley, CA 94720, USA.

Articles citing this

Functional and mechanistic diversity of distal transcription enhancers. Cell (2011) 5.22

Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura. Genome Biol (2004) 3.36

Transcriptional enhancers in animal development and evolution. Curr Biol (2010) 2.41

Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila. Development (2005) 2.25

Looping back to leap forward: transcription enters a new era. Cell (2014) 1.93

Dynamic reprogramming of chromatin accessibility during Drosophila embryo development. Genome Biol (2011) 1.61

The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances. Dev Cell (2016) 1.45

Functional and topological characteristics of mammalian regulatory domains. Genome Res (2014) 1.43

Study of the functional interaction between Mcp insulators from the Drosophila bithorax complex: effects of insulator pairing on enhancer-promoter communication. Mol Cell Biol (2007) 1.29

Enhancer-promoter communication at the yellow gene of Drosophila melanogaster: diverse promoters participate in and regulate trans interactions. Genetics (2006) 1.12

Long- and short-range transcriptional repressors induce distinct chromatin states on repressed genes. Curr Biol (2011) 1.04

Regulation and function of the peg3 imprinted domain. Genomics Inform (2014) 1.01

Evolving enhancer-promoter interactions within the tinman complex of the flour beetle, Tribolium castaneum. Development (2009) 0.99

Global transcriptional regulation of the locus encoding the skeletal muscle determination genes Mrf4 and Myf5. Genes Dev (2008) 0.98

Drosophila gypsy insulator and yellow enhancers regulate activity of yellow promoter through the same regulatory element. Chromosoma (2007) 0.97

Comparing enhancer action in cis and in trans. Genetics (2012) 0.97

A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes. PLoS Genet (2015) 0.97

TELOMERASE ACTIVATOR1 induces telomerase activity and potentiates responses to auxin in Arabidopsis. Plant Cell (2004) 0.93

Zeste can facilitate long-range enhancer-promoter communication and insulator bypass in Drosophila melanogaster. Chromosoma (2009) 0.93

How to make stripes: deciphering the transition from non-periodic to periodic patterns in Drosophila segmentation. Development (2011) 0.88

CCAT: Combinatorial Code Analysis Tool for transcriptional regulation. Nucleic Acids Res (2013) 0.86

The abdominal-B promoter tethering element mediates promoter-enhancer specificity at the Drosophila bithorax complex. Fly (Austin) (2008) 0.83

Disruption of the abdominal-B promoter tethering element results in a loss of long-range enhancer-directed Hox gene expression in Drosophila. PLoS One (2011) 0.81

Variation and constraint in Hox gene evolution. Proc Natl Acad Sci U S A (2013) 0.79

Epigenetics as an answer to Darwin's "special difficulty," Part 2: natural selection of metastable epialleles in honeybee castes. Front Genet (2015) 0.77

The Capacity to Act in Trans Varies Among Drosophila Enhancers. Genetics (2016) 0.77

Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex. PLoS Genet (2016) 0.77

An Organizational Hub of Developmentally Regulated Chromatin Loops in the Drosophila Antennapedia Complex. Mol Cell Biol (2015) 0.76

Trans-repression of gene activity upstream of T-DNA tagged RLK902 links Arabidopsis root growth inhibition and downy mildew resistance. PLoS One (2011) 0.76

Chromatin boundary elements organize genomic architecture and developmental gene regulation in Drosophila Hox clusters. World J Biol Chem (2016) 0.75

Mapping the D.melanogaster En1A Enhancer Modules Responsible for Transcription Activation and Long-Distance Enhancer-Promoter Interactions. Acta Naturae (2017) 0.75

Functional organization of the white gene enhancer in Drosophila melanogaster. Dokl Biochem Biophys (2015) 0.75

Sex combs reduced (Scr) regulatory region of Drosophila revisited. Mol Genet Genomics (2017) 0.75

Articles cited by this

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma (1989) 16.41

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome. Proc Natl Acad Sci U S A (2002) 8.56

Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo. Proc Natl Acad Sci U S A (2001) 6.39

Going the distance: a current view of enhancer action. Science (1998) 5.83

Control elements of the Drosophila segmentation gene fushi tarazu. Cell (1985) 4.83

Regulation of even-skipped stripe 2 in the Drosophila embryo. EMBO J (1992) 4.63

Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell (1987) 3.91

The RNA polymerase II core promoter: a key component in the regulation of gene expression. Genes Dev (2002) 3.87

The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes Dev (1991) 3.45

DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1. Genes Dev (1991) 3.10

Characterization of the intergenic RNA profile at abdominal-A and Abdominal-B in the Drosophila bithorax complex. Proc Natl Acad Sci U S A (2002) 2.94

DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A (1991) 2.51

Spatial distribution of Antennapedia transcripts during Drosophila development. EMBO J (1983) 2.50

Different core promoters possess distinct regulatory activities in the Drosophila embryo. Genes Dev (1998) 2.38

Spatially ordered transcription of regulatory DNA in the bithorax complex of Drosophila. Development (1989) 2.07

The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell (1990) 1.99

Characterization of the transvection mediating region of the abdominal-B locus in Drosophila. Development (1999) 1.76

Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated. Genes Dev (1990) 1.75

Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex. Proc Natl Acad Sci U S A (2002) 1.74

Promoter specificity mediates the independent regulation of neighboring genes. Genes Dev (1996) 1.60

Transcription through the iab-7 cis-regulatory domain of the bithorax complex interferes with maintenance of Polycomb-mediated silencing. Development (2002) 1.59

Transcriptional control of Drosophila fushi tarazu zebra stripe expression. Genes Dev (1989) 1.58

Cloning and transcriptional analysis of the segmentation gene fushi tarazu of Drosophila. Cell (1984) 1.55

Near-reciprocal phenotypes caused by inactivation or indiscriminate expression of the Drosophila segmentation gene ftz. Nature (1986) 1.48

Compatibility between enhancers and promoters determines the transcriptional specificity of gooseberry and gooseberry neuro in the Drosophila embryo. EMBO J (1994) 1.47

Characterization of the cis-regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics (1995) 1.22

The beetle Tribolium castaneum has a fushi tarazu homolog expressed in stripes during segmentation. Proc Natl Acad Sci U S A (1994) 1.21

Drosophila fushi tarazu. a gene on the border of homeotic function. Curr Biol (2001) 1.17

Regulation of the segmentation gene fushi tarazu has been functionally conserved in Drosophila. EMBO J (1990) 1.13

Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2. Mol Cell Biol (1993) 1.09

Evidence for the derivation of the Drosophila fushi tarazu gene from a Hox gene orthologous to lophotrochozoan Lox5. Curr Biol (2000) 1.08

Dosage compensation rox! Curr Opin Cell Biol (2000) 1.04

Identification of GATA-1 and NF-E2 binding sites in the flanking regions of the human alpha-globin genes. Acta Haematol (1992) 0.84

fushi tarazu: a Hox gene changes its role. Bioessays (2002) 0.82

Articles by these authors

The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science (2002) 11.11

RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo. Nat Genet (2007) 9.56

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome. Proc Natl Acad Sci U S A (2002) 8.56

Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo. Genes Dev (2007) 4.59

Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo. Cell (2002) 4.00

Synchronous and stochastic patterns of gene activation in the Drosophila embryo. Science (2009) 3.58

Genomic regulatory networks and animal development. Dev Cell (2005) 3.01

Characterization of the intergenic RNA profile at abdominal-A and Abdominal-B in the Drosophila bithorax complex. Proc Natl Acad Sci U S A (2002) 2.94

Regulatory blueprint for a chordate embryo. Science (2006) 2.67

Shadow enhancers foster robustness of Drosophila gastrulation. Curr Biol (2010) 2.63

Immunity regulatory DNAs share common organizational features in Drosophila. Mol Cell (2004) 2.58

A regulatory code for neurogenic gene expression in the Drosophila embryo. Development (2004) 2.41

miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data. Genome Biol (2010) 2.18

Dorsal gradient networks in the Drosophila embryo. Dev Biol (2002) 2.18

Coordinate enhancers share common organizational features in the Drosophila genome. Proc Natl Acad Sci U S A (2004) 1.90

Multiple enhancers ensure precision of gap gene-expression patterns in the Drosophila embryo. Proc Natl Acad Sci U S A (2011) 1.80

Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex. Proc Natl Acad Sci U S A (2002) 1.74

pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos. Genes Dev (2004) 1.73

Ciona intestinalis: an emerging model for whole-genome analyses. Trends Genet (2003) 1.69

Quantitative analysis of binding motifs mediating diverse spatial readouts of the Dorsal gradient in the Drosophila embryo. Proc Natl Acad Sci U S A (2005) 1.67

Clusters of temporal discordances reveal distinct embryonic patterning mechanisms in Drosophila and anopheles. PLoS Biol (2011) 1.65

The snail repressor inhibits release, not elongation, of paused Pol II in the Drosophila embryo. Curr Biol (2011) 1.63

Regulation of Hox gene activity by transcriptional elongation in Drosophila. Curr Biol (2009) 1.55

Stalled Hox promoters as chromosomal boundaries. Genes Dev (2009) 1.55

A simplified miRNA-based gene silencing method for Drosophila melanogaster. Dev Biol (2008) 1.54

Neural-specific elongation of 3' UTRs during Drosophila development. Proc Natl Acad Sci U S A (2011) 1.40

Mechanisms of transcriptional precision in animal development. Trends Genet (2012) 1.38

Genome-wide identification of tissue-specific enhancers in the Ciona tadpole. Proc Natl Acad Sci U S A (2002) 1.36

Evolutionary origins of the vertebrate heart: Specification of the cardiac lineage in Ciona intestinalis. Proc Natl Acad Sci U S A (2003) 1.34

The transcription/migration interface in heart precursors of Ciona intestinalis. Science (2008) 1.32

Early chordate origins of the vertebrate second heart field. Science (2010) 1.31

Identification of a rudimentary neural crest in a non-vertebrate chordate. Nature (2012) 1.30

Uncoupling heart cell specification and migration in the simple chordate Ciona intestinalis. Development (2005) 1.27

Decoding cis-regulatory DNAs in the Drosophila genome. Curr Opin Genet Dev (2002) 1.26

Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene. Nat Neurosci (2011) 1.26

Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo. Dev Biol (2009) 1.26

Localized repressors delineate the neurogenic ectoderm in the early Drosophila embryo. Dev Biol (2005) 1.23

Ventral dominance governs sequential patterns of gene expression across the dorsal-ventral axis of the neuroectoderm in the Drosophila embryo. Dev Biol (2003) 1.19

Whole-genome analysis of Drosophila gastrulation. Curr Opin Genet Dev (2004) 1.18

A genomewide survey of developmentally relevant genes in Ciona intestinalis. I. Genes for bHLH transcription factors. Dev Genes Evol (2003) 1.18

Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset. Development (2002) 1.16

ELAV mediates 3' UTR extension in the Drosophila nervous system. Genes Dev (2012) 1.16

International EMS systems: The United States: past, present, and future. Resuscitation (2004) 1.14

Precision of hunchback expression in the Drosophila embryo. Curr Biol (2012) 1.14

Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system. Development (2008) 1.12

A genomewide survey of developmentally relevant genes in Ciona intestinalis. II. Genes for homeobox transcription factors. Dev Genes Evol (2003) 1.11

Rapid transcription fosters coordinate snail expression in the Drosophila embryo. Cell Rep (2013) 1.10

Analysis of the Tribolium homeotic complex: insights into mechanisms constraining insect Hox clusters. Dev Genes Evol (2008) 1.09

The cardiovascular effects of cocaine. J Emerg Med (2005) 1.08

Electroporation of transgenic DNAs in the sea squirt Ciona. Cold Spring Harb Protoc (2009) 1.07

The Snail repressor positions Notch signaling in the Drosophila embryo. Development (2002) 1.06

Organization of developmental enhancers in the Drosophila embryo. Nucleic Acids Res (2009) 1.06

Acute Methylenedioxypyrovalerone Toxicity. J Med Toxicol (2015) 1.04

The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo. Mol Cell (2011) 1.02

Neural tube patterning by Ephrin, FGF and Notch signaling relays. Development (2011) 1.02

FGF signaling establishes the anterior border of the Ciona neural tube. Development (2012) 1.00

The Drosophila gap gene network is composed of two parallel toggle switches. PLoS One (2011) 1.00

Evolving enhancer-promoter interactions within the tinman complex of the flour beetle, Tribolium castaneum. Development (2009) 0.99

Analyzing gene regulation in ascidian embryos: new tools for new perspectives. Differentiation (2002) 0.99

A genomewide survey of developmentally relevant genes in Ciona intestinalis. III. Genes for Fox, ETS, nuclear receptors and NFkappaB. Dev Genes Evol (2003) 0.98

Conservation patterns in different functional sequence categories of divergent Drosophila species. Genomics (2006) 0.97

Ethanol ingestion in two infants under 2 months old: a previously unreported cause of ALTE. Pediatrics (2013) 0.93

Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila. Proc Natl Acad Sci U S A (2010) 0.93

Spatio-temporal intersection of Lhx3 and Tbx6 defines the cardiac field through synergistic activation of Mesp. Dev Biol (2009) 0.92

FGF3 in the floor plate directs notochord convergent extension in the Ciona tadpole. Development (2008) 0.91

Neuronal subtype specification in the spinal cord of a protovertebrate. Development (2011) 0.91

Transcriptional repression via antilooping in the Drosophila embryo. Proc Natl Acad Sci U S A (2012) 0.89

Whole-mount in situ hybridization on sea squirt (Ciona intestinalis) embryos. Cold Spring Harb Protoc (2009) 0.89

Isolation of sea squirt (Ciona) gametes, fertilization, dechorionation, and development. Cold Spring Harb Protoc (2009) 0.89

CtBP-independent repression in the Drosophila embryo. Mol Cell Biol (2003) 0.89

Tail morphogenesis in the ascidian, Ciona intestinalis, requires cooperation between notochord and muscle. Dev Biol (2002) 0.89

Media effects of experimental presentation of the ideal physique on eating disorder symptoms: a meta-analysis of laboratory studies. Clin Psychol Rev (2012) 0.89

BMP signaling coordinates gene expression and cell migration during precardiac mesoderm development. Dev Biol (2009) 0.88

Mosaic and regulative development: two faces of one coin. Curr Biol (2006) 0.88

Unraveling genomic regulatory networks in the simple chordate, Ciona intestinalis. Genome Res (2005) 0.88

Time series analysis of human and bovine brucellosis in South Korea from 2005 to 2010. Prev Vet Med (2012) 0.88

Control of intercalation is cell-autonomous in the notochord of Ciona intestinalis. Dev Biol (2002) 0.86

Modified reperfusion and ischemia-reperfusion injury in human lung transplantation. J Thorac Cardiovasc Surg (2003) 0.86

Liberalization of donor criteria in lung transplantation. Am Surg (2003) 0.84

p120RasGAP mediates ephrin/Eph-dependent attenuation of FGF/ERK signals during cell fate specification in ascidian embryos. Development (2013) 0.84

The sea squirt Ciona intestinalis. Cold Spring Harb Protoc (2009) 0.84

Whole-genome expression profiles identify gene batteries in Drosophila. Dev Cell (2002) 0.84

Morphogen gradients: limits to signaling or limits to measurement? Curr Biol (2010) 0.82

Case files of the medical toxicology fellowship at Banner Good Samaritan Medical Center in Phoenix, AZ: methemoglobinemia following dapsone exposure. J Med Toxicol (2011) 0.82

Microinjection of morpholino oligos and RNAs in sea squirt (Ciona) embryos. Cold Spring Harb Protoc (2009) 0.81

Meteorological influence on the occurrence of gastric dilatation-volvulus in military working dogs in Texas. Int J Biometeorol (2007) 0.81

Toxicology in the ICU: Part 2: specific toxins. Chest (2011) 0.80

Isolation of individual cells and tissues from electroporated sea squirt (Ciona) embryos by fluorescence-activated cell sorting (FACS). Cold Spring Harb Protoc (2009) 0.80

Diphenhydramine-induced Brugada pattern. Resuscitation (2010) 0.80

Computational identification of regulatory DNAs underlying animal development. Nat Methods (2005) 0.80

HOT DNAs: a novel class of developmental enhancers. Genes Dev (2012) 0.80

Recurrent seizures and serotonin syndrome following "2C-I" ingestion. J Med Toxicol (2013) 0.80

Coordinate regulation of an extended chromosome domain. Cell (2003) 0.79

The prognostic significance of frequency and morphology of premature ventricular complexes during ambulatory holter monitoring. Ann Noninvasive Electrocardiol (2012) 0.78

Activation, proliferation and commitment of endogenous stem/progenitor cells to the oligodendrocyte lineage by TS1 in a rat model of dysmyelination. Dev Neurosci (2006) 0.78

Concordance of field and emergency department assessment in the prehospital management of patients with dyspnea. Prehosp Emerg Care (2003) 0.78

Case files of the Medical Toxicology Fellowship at Banner Good Samaritan Medical Center in Phoenix, AZ: a non-warfarin anticoagulant overdose. J Med Toxicol (2009) 0.77

Methodology for AACT evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning. Clin Toxicol (Phila) (2015) 0.77

Preference for monthly darbepoetin alfa dosing in patients with chronic kidney disease not receiving dialysis. Curr Med Res Opin (2006) 0.76