Published in Neurogastroenterol Motil on October 01, 2011
A randomised controlled study of the effect of cholinesterase inhibition on colon function in patients with diabetes mellitus and constipation. Gut (2012) 0.94
Constipation-predominant irritable bowel syndrome: a review of current and emerging drug therapies. World J Gastroenterol (2014) 0.86
Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. BMC Pharmacol (2012) 0.83
Effective Constipation Treatment Changes More Than Bowel Frequency: A Systematic Review and Meta-Analysis. J Neurogastroenterol Motil (2016) 0.82
Irritable bowel syndrome: new insights into symptom mechanisms and advances in treatment. F1000Res (2016) 0.77
Comparison of pyridostigmine and bisacodyl in the treatment of refractory chronic constipation. Caspian J Intern Med (2016) 0.77
Lubiprostone for the treatment of adult women with irritable bowel syndrome with constipation. Clin Med Insights Gastroenterol (2012) 0.76
Management Strategies for Abdominal Bloating and Distension. Gastroenterol Hepatol (N Y) (2014) 0.76
Tong Xie Yao Fang relieves irritable bowel syndrome in rats via mechanisms involving regulation of 5-hydroxytryptamine and substance P. World J Gastroenterol (2015) 0.75
Open channels for functional bowel disorders: guanylate cyclase C agonists in IBS and CC. Dig Dis Sci (2013) 0.75
Rectal tone and compliance affected in patients with fecal incontinence after fistulotomy. World J Gastroenterol (2015) 0.75
Targeting Small Bowel Receptors to Treat Constipation and Diarrhea. Curr Gastroenterol Rep (2017) 0.75
Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol (1997) 8.81
The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther (1997) 5.78
Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. Gastroenterology (2003) 3.77
Soluble or insoluble fibre in irritable bowel syndrome in primary care? Randomised placebo controlled trial. BMJ (2009) 2.51
SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents. Am J Physiol Cell Physiol (2004) 2.33
Lubiprostone, a locally acting chloride channel activator, in adult patients with chronic constipation: a double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety. Aliment Pharmacol Ther (2007) 2.08
Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome--results of two randomized, placebo-controlled studies. Aliment Pharmacol Ther (2008) 2.06
Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers. Am J Physiol Gastrointest Liver Physiol (2006) 1.94
Clinical trial: phase 2 study of lubiprostone for irritable bowel syndrome with constipation. Aliment Pharmacol Ther (2008) 1.50
Contributions of pain sensitivity and colonic motility to IBS symptom severity and predominant bowel habits. Am J Gastroenterol (2008) 1.29
Gastrointestinal and colonic segmental transit time evaluated by a single abdominal x-ray in healthy subjects and constipated patients. Scand J Gastroenterol Suppl (1988) 1.26
Psychometric evaluation of patient-reported outcomes in irritable bowel syndrome randomized controlled trials: a Rome Foundation report. Gastroenterology (2009) 1.11
Effect of a chloride channel activator, lubiprostone, on colonic sensory and motor functions in healthy subjects. Am J Physiol Gastrointest Liver Physiol (2008) 1.09
Pain from rectal distension in women with irritable bowel syndrome: relationship to sexual abuse. Dig Dis Sci (1997) 1.08
Cognitive behavioural therapy in addition to antispasmodic therapy for irritable bowel syndrome in primary care: randomised controlled trial. Health Technol Assess (2006) 0.96
Lubiprostone: chloride channel activator for chronic constipation. Clin Ther (2006) 0.87
Lubiprostone: in constipation-predominant irritable bowel syndrome. Drugs (2009) 0.84
Midwife managed delivery unit: a randomised controlled comparison with consultant led care. BMJ (1994) 4.23
Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur J Immunol (1988) 4.20
cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis. Nature (1993) 2.96
Expression of a polypeptide containing a dipeptide repeat is confined to the insect stage of Trypanosoma brucei. Nature (1987) 2.86
Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site. EMBO J (1986) 2.85
BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports. J Med Genet (2008) 2.79
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. Nature (1995) 2.78
A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J Exp Med (1997) 2.76
The small subunit of HL-A antigens is beta 2-microglobulin. J Exp Med (1973) 2.68
The morbidity and mortality of vermiculite miners and millers exposed to tremolite-actinolite: Part I. Exposure estimates. Am J Ind Med (1987) 2.66
Fire on an intensive care unit caused by an oxygen cylinder. Anaesthesia (2012) 2.61
Modulation of cytokine production by transforming growth factor-beta. J Immunol (1989) 2.42
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J (1997) 2.34
Human ret proto-oncogene mapped to chromosome 10q11.2. Oncogene (1989) 2.17
Costs of health care for irritable bowel syndrome, chronic constipation, functional diarrhoea and functional abdominal pain. Aliment Pharmacol Ther (2007) 2.09
Human T-lymphotropic virus type III (HTLV-III) infection in seronegative haemophiliacs after transfusion of factor VIII. Lancet (1985) 2.08
Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha. Clin Exp Immunol (1988) 2.06
Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. J Clin Periodontol (1997) 2.05
Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation. Nat Immunol (2001) 2.03
Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells. Eur J Immunol (1990) 2.01
The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways. Proc Natl Acad Sci U S A (1999) 1.98
Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha. Eur J Immunol (1991) 1.87
Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells. Oncogene (1996) 1.77
The efficiency of multilocus DNA fingerprint probes for individualization and establishment of family relationships, determined from extensive casework. Am J Hum Genet (1991) 1.76
Neuropsychological dysfunction following repeat concussions in jockeys. J Neurol Neurosurg Psychiatry (2006) 1.71
Preparation and characterization of RNA standards for use in quantitative branched DNA hybridization assays. Anal Biochem (1995) 1.69
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Is rectal pain sensitivity a biological marker for irritable bowel syndrome: psychological influences on pain perception. Gastroenterology (1998) 1.66
Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis (1990) 1.61
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Vasa previa: an avoidable obstetric tragedy. Obstet Gynecol Surv (1999) 1.55
New variant Creutzfeldt-Jakob disease: psychiatric features. Lancet (1997) 1.55
A randomized trial comparing heater probe plus thrombin with heater probe plus placebo for bleeding peptic ulcer. Gastroenterology (2003) 1.54
Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1. Arch Dermatol (1997) 1.53
Reducing the risk of retained throat packs after surgery. Br J Oral Maxillofac Surg (2012) 1.48
2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei. J Mol Biol (1990) 1.48
Phase I/II study of vaccination with dendritic-like leukaemia cells for the immunotherapy of acute myeloid leukaemia. Br J Haematol (2006) 1.48
Ulnar 'dive' identification of the median nerve in the forearm. Anaesthesia (2014) 1.45
Patent foramen ovale and decompression illness in divers. Lancet (1996) 1.44
Reduced anisotropy of action potential conduction in left ventricular hypertrophy. J Cardiovasc Electrophysiol (2001) 1.43
TAP blocks in breast reconstructions using abdominal wall tissue. Anaesthesia (2011) 1.41
Apparent removal of graft-versus-leukaemia effect by the use of leucocyte-poor blood components in patients with acute myeloblastic leukaemia. Br J Haematol (1989) 1.40
Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein. Proc Natl Acad Sci U S A (1990) 1.40
Whatever happened to cervical cytology automation? Anal Cell Pathol (1990) 1.39
Modeling of treatment response to erythropoiesis-stimulating agents as a function of center- and patient-related variables: results from the Anemia Cancer Treatment (ACT) study. Ann Oncol (2009) 1.39
A simple technique to control the hair and enhance draping for major head and neck surgery. Br J Oral Maxillofac Surg (2011) 1.38
The status of older adolescents at exit from out-of-home care. Child Welfare (1999) 1.37
Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets. Blood (1999) 1.35
Tumour necrosis factor as an autocrine tumour growth factor for chronic B-cell malignancies. Lancet (1988) 1.35
Variant specific glycoprotein of Trypanosoma brucei consists of two domains each having an independently conserved pattern of cysteine residues. J Mol Biol (1991) 1.31
Fc epsilon receptor I-associated lyn-dependent phosphorylation of Fc gamma receptor IIB during negative regulation of mast cell activation. J Immunol (1998) 1.28
Age-related changes in proprioception and sensation of joint position. Acta Orthop Scand (1985) 1.27
Continuing medical education using clinical algorithms. A controlled-trial assessment of effect on neonatal care. Am J Dis Child (1986) 1.26
CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav. Immunity (1998) 1.25
Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain. J Neurosci (2001) 1.24
Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms. J Exp Med (2001) 1.23
Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2012) 1.23
Long-term hospitalization for tuberculosis control. Experience with a medical-psychosocial inpatient unit. JAMA (1997) 1.22
p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep smears. J Clin Pathol (2003) 1.22
Detection of transforming growth factor-beta in rheumatoid arthritis synovial tissue: lack of effect on spontaneous cytokine production in joint cell cultures. Clin Exp Immunol (1990) 1.21
Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets. J Biol Chem (1999) 1.21
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19
Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76 TeV. Phys Rev Lett (2012) 1.19
Angiotropic large cell lymphoma (ALCL): morphological, immunohistochemical and genotypic studies with analysis of previous reports. Hematol Oncol (1989) 1.18
Intrahepatic genetic inoculation of hepatitis C virus RNA confers cross-protective immunity. J Virol (2001) 1.17
Utility of red flag symptom exclusions in the diagnosis of irritable bowel syndrome. Aliment Pharmacol Ther (2006) 1.17
An analysis of injuries resulting from professional horse racing in France during 1991-2001: a comparison with injuries resulting from professional horse racing in Great Britain during 1992-2001. Br J Sports Med (2006) 1.17
Similar organization of the nusA-infB operon in Bacillus subtilis and Escherichia coli. J Bacteriol (1993) 1.16
Aneurysms of the portal vein and superior mesenteric vein. Abdom Imaging (1997) 1.14
Analysis of intrathyroidal cytokine production in thyroid autoimmune disease: thyroid follicular cells produce interleukin-1 alpha and interleukin-6. Clin Exp Immunol (1989) 1.13
Observations on the pathogenesis of the pneumonitis associated with severe infections in other parts of the body. Ann Surg (1968) 1.13
The effect of previous lower abdominal surgery on performing the total extraperitoneal approach to laparoscopic herniorrhaphy. Am Surg (1996) 1.12
Cannabinoids attenuate capsaicin-evoked hyperalgesia through spinal and peripheral mechanisms. Pain (2001) 1.12
The usual medical care for irritable bowel syndrome. Aliment Pharmacol Ther (2004) 1.11
The release of prion protein from platelets during storage of apheresis platelets. Transfusion (2001) 1.11
A comparison of the responses of staphylococci and streptococci to teicoplanin and vancomycin. J Antimicrob Chemother (1987) 1.11
Search for a W' or techni-ρ decaying into WZ in pp Collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2012) 1.10
Anthrax in humans in Zimbabwe. Cent Afr J Med (1980) 1.10
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy. Phys Rev Lett (2012) 1.09
Interfacial adsorption of simple lipid mixtures combined with hydrophobic surfactant protein from pig lung. Biochem Cell Biol (1992) 1.09
Sun safety: avoiding noonday sun, wearing protective clothing, and the use of sunscreen. J Natl Cancer Inst (1998) 1.09
Peripheral genotype-phenotype correlations in Asian Indians with type 2 diabetes mellitus. J Assoc Physicians India (2005) 1.08
The United Kingdom Primary Immune Deficiency (UKPID) Registry: report of the first 4 years' activity 2008-2012. Clin Exp Immunol (2014) 1.08
Identification and characterization of cDNA clones encoding antigens of Eimeria tenella. Mol Biochem Parasitol (1988) 1.08
Pain from rectal distension in women with irritable bowel syndrome: relationship to sexual abuse. Dig Dis Sci (1997) 1.08
Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice. Eur J Immunol (1999) 1.08
Application of a time-resolved fluoroimmunoassay for the analysis of normal prion protein in human blood and its components. Vox Sang (1999) 1.08
Search for supersymmetry at the LHC in events with jets and missing transverse energy. Phys Rev Lett (2011) 1.08
Using willingness to pay to value alternative models of antenatal care. Soc Sci Med (1997) 1.08
Pyridoxine dependent seizures--a wider clinical spectrum. Arch Dis Child (1983) 1.08
Vav-2 controls NFAT-dependent transcription in B- but not T-lymphocytes. EMBO J (2000) 1.08
Search for stopped Gluinos in pp collisions at square root s=7 TeV. Phys Rev Lett (2011) 1.07
Two variant surface glycoproteins of Trypanosoma brucei of different sequence classes have similar 6 A resolution X-ray structures. Nature (1987) 1.07