PubRank

Karen Reue

Author PubWeight™ 96.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lipin, a lipodystrophy and obesity gene. Cell Metab 2005 3.16
2 Lamins A and C but not lamin B1 regulate nuclear mechanics. J Biol Chem 2006 3.02
3 Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A 2004 2.89
4 Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J Biol Chem 2006 2.89
5 Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet 2007 2.60
6 Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet 2008 2.49
7 Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis. J Biol Chem 2005 2.42
8 Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci U S A 2004 2.39
9 UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J 2011 2.36
10 The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab 2007 2.32
11 Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. J Biol Chem 2004 2.25
12 Metabolic state of glioma stem cells and nontumorigenic cells. Proc Natl Acad Sci U S A 2011 2.13
13 The number of x chromosomes causes sex differences in adiposity in mice. PLoS Genet 2012 2.02
14 Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell 2011 1.86
15 Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis. Am J Physiol Endocrinol Metab 2009 1.85
16 Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity. J Lipid Res 2006 1.68
17 Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res 2006 1.62
18 Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol 2013 1.61
19 Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metab 2009 1.56
20 Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem 2003 1.51
21 Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation. Diabetes 2006 1.48
22 Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. Diabetes 2009 1.46
23 Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice. J Lipid Res 2008 1.44
24 Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome 2012 1.43
25 A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2. J Biol Chem 2009 1.40
26 The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL. J Lipid Res 2008 1.39
27 Phosphatidate degradation: phosphatidate phosphatases (lipins) and lipid phosphate phosphatases. Biochim Biophys Acta 2009 1.38
28 NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arterioscler Thromb Vasc Biol 2010 1.32
29 Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis. J Lipid Res 2008 1.29
30 Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. Hum Mol Genet 2005 1.25
31 Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically. J Lipid Res 2008 1.25
32 Lipins: multifunctional lipid metabolism proteins. Annu Rev Nutr 2010 1.24
33 Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs. Cell Metab 2013 1.22
34 Cell nuclei spin in the absence of lamin b1. J Biol Chem 2007 1.22
35 Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men. J Clin Endocrinol Metab 2007 1.21
36 Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal 2010 1.21
37 Lipin deficiency impairs diurnal metabolic fuel switching. Diabetes 2006 1.19
38 Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes. J Biol Chem 2009 1.19
39 Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem 2011 1.17
40 ABCC6 localizes to the mitochondria-associated membrane. Circ Res 2012 1.14
41 An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res 2013 1.12
42 Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance. J Biol Chem 2010 1.11
43 Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor γ (PPARγ) gene expression during adipogenesis. J Biol Chem 2011 1.11
44 Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models. Hum Mol Genet 2009 1.09
45 GPIHBP1, an endothelial cell transporter for lipoprotein lipase. J Lipid Res 2011 1.08
46 A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res 2002 1.08
47 Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. Arterioscler Thromb Vasc Biol 2012 1.08
48 HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle. Diabetes 2013 1.07
49 Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling. Prog Lipid Res 2013 1.06
50 Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels. Cell Metab 2013 1.03
51 Metabolic impact of sex chromosomes. Adipocyte 2013 1.00
52 Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. Arterioscler Thromb Vasc Biol 2011 0.99
53 Metabolic differences in breast cancer stem cells and differentiated progeny. Breast Cancer Res Treat 2014 0.98
54 X and Y chromosome complement influence adiposity and metabolism in mice. Endocrinology 2013 0.98
55 Cell-autonomous sex determination outside of the gonad. Dev Dyn 2013 0.97
56 Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice. Arterioscler Thromb Vasc Biol 2010 0.93
57 Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Proc Natl Acad Sci U S A 2012 0.92
58 Biphasic expression of lipin suggests dual roles in adipocyte development. Drug News Perspect 2005 0.92
59 A thematic review series: lipid droplet storage and metabolism: from yeast to man. J Lipid Res 2011 0.91
60 PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Mol Metab 2013 0.90
61 The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism. J Biol Chem 2001 0.89
62 Ulcerative dermatitis in C57BL/6 mice exhibits an oxidative stress response consistent with normal wound healing. Comp Med 2012 0.89
63 Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res 2012 0.88
64 Follistatin promotes adipocyte differentiation, browning, and energy metabolism. J Lipid Res 2014 0.83
65 Response to Pomozi et al's research commentary. Circ Res 2013 0.79
66 Hoofbeats, zebras, and insights into insulin resistance. J Clin Invest 2009 0.79
67 Lipin-1 flexes its muscle in autophagy. Cell Cycle 2014 0.75
68 RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest 2017 0.75
69 UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J 2016 0.75
70 Women in Metabolism: Part 3. Cell Metab 2015 0.75