Published in J Lipid Res on December 01, 2002
Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A (2004) 2.89
The aldo-keto reductase superfamily and its role in drug metabolism and detoxification. Drug Metab Rev (2008) 1.80
MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor. Proc Natl Acad Sci U S A (2012) 1.20
Genomewide discovery and classification of candidate ovarian fertility genes in the mouse. Genetics (2007) 1.18
Impaired neurosteroid synthesis in multiple sclerosis. Brain (2011) 1.05
Transplacental exposure to inorganic arsenic at a hepatocarcinogenic dose induces fetal gene expression changes in mice indicative of aberrant estrogen signaling and disrupted steroid metabolism. Toxicol Appl Pharmacol (2007) 0.97
AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids. J Biol Chem (2010) 0.91
Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers. Mol Cancer (2009) 0.88
The therapeutic potential of umbilical cord mesenchymal stem cells in mice premature ovarian failure. Biomed Res Int (2013) 0.86
Tissue distribution, ontogeny, and chemical induction of aldo-keto reductases in mice. Drug Metab Dispos (2013) 0.84
Characterization of the aldo-keto reductase 1C gene cluster on pig chromosome 10: possible associations with reproductive traits. BMC Vet Res (2006) 0.83
Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone. BMC Biochem (2005) 0.79
Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.77
Quantitative evaluation of aldo-keto reductase expression in hepatocellular carcinoma (HCC) cell lines. Genomics Proteomics Bioinformatics (2013) 0.76
Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State. Immunity (2017) 0.75
An update on the mouse liver proteome. Proteome Sci (2009) 0.75
Lipin, a lipodystrophy and obesity gene. Cell Metab (2005) 3.16
Lamins A and C but not lamin B1 regulate nuclear mechanics. J Biol Chem (2006) 3.02
Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A (2004) 2.89
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J Biol Chem (2006) 2.89
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet (2007) 2.60
Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet (2008) 2.49
Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis. J Biol Chem (2005) 2.42
Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci U S A (2004) 2.39
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J (2011) 2.36
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab (2007) 2.32
Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. J Biol Chem (2004) 2.25
Metabolic state of glioma stem cells and nontumorigenic cells. Proc Natl Acad Sci U S A (2011) 2.13
The number of x chromosomes causes sex differences in adiposity in mice. PLoS Genet (2012) 2.02
Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell (2011) 1.86
Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis. Am J Physiol Endocrinol Metab (2009) 1.85
Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology (2014) 1.83
Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations. Hepatology (2013) 1.81
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity. J Lipid Res (2006) 1.68
Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res (2006) 1.62
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol (2013) 1.61
Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metab (2009) 1.56
Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem (2003) 1.51
Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation. Diabetes (2006) 1.48
Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. Diabetes (2009) 1.46
Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice. J Lipid Res (2008) 1.44
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome (2012) 1.43
Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism. Prostate (2003) 1.40
A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2. J Biol Chem (2009) 1.40
The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL. J Lipid Res (2008) 1.39
Phosphatidate degradation: phosphatidate phosphatases (lipins) and lipid phosphate phosphatases. Biochim Biophys Acta (2009) 1.38
NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arterioscler Thromb Vasc Biol (2010) 1.32
Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis. J Lipid Res (2008) 1.29
Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. Hum Mol Genet (2005) 1.25
Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically. J Lipid Res (2008) 1.25
Lipins: multifunctional lipid metabolism proteins. Annu Rev Nutr (2010) 1.24
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs. Cell Metab (2013) 1.22
Cell nuclei spin in the absence of lamin b1. J Biol Chem (2007) 1.22
Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men. J Clin Endocrinol Metab (2007) 1.21
Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics (2012) 1.21
Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal (2010) 1.21
Lipin deficiency impairs diurnal metabolic fuel switching. Diabetes (2006) 1.19
Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes. J Biol Chem (2009) 1.19
Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem (2011) 1.17
Urinary side effects and complications after permanent prostate brachytherapy: the MD Anderson Cancer Center experience. Urology (2009) 1.15
ABCC6 localizes to the mitochondria-associated membrane. Circ Res (2012) 1.14
Induction of AKR1C2 by phase II inducers: identification of a distal consensus antioxidant response element regulated by NRF2. Mol Pharmacol (2006) 1.12
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res (2013) 1.12
Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance. J Biol Chem (2010) 1.11
Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor γ (PPARγ) gene expression during adipogenesis. J Biol Chem (2011) 1.11
Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models. Hum Mol Genet (2009) 1.09
GPIHBP1, an endothelial cell transporter for lipoprotein lipase. J Lipid Res (2011) 1.08
Metabolic consequences of lipodystrophy in mouse models. Curr Opin Clin Nutr Metab Care (2006) 1.08
Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. Arterioscler Thromb Vasc Biol (2012) 1.08
HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle. Diabetes (2013) 1.07
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling. Prog Lipid Res (2013) 1.06
Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling. Cancer Res (2004) 1.05
Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels. Cell Metab (2013) 1.03
Metabolic impact of sex chromosomes. Adipocyte (2013) 1.00
Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. Arterioscler Thromb Vasc Biol (2011) 0.99
Metabolic differences in breast cancer stem cells and differentiated progeny. Breast Cancer Res Treat (2014) 0.98
X and Y chromosome complement influence adiposity and metabolism in mice. Endocrinology (2013) 0.98
Impaired dihydrotestosterone catabolism in human prostate cancer: critical role of AKR1C2 as a pre-receptor regulator of androgen receptor signaling. Cancer Res (2007) 0.97
Cell-autonomous sex determination outside of the gonad. Dev Dyn (2013) 0.97
Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice. Arterioscler Thromb Vasc Biol (2010) 0.93
Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Proc Natl Acad Sci U S A (2012) 0.92
Biphasic expression of lipin suggests dual roles in adipocyte development. Drug News Perspect (2005) 0.92
A thematic review series: lipid droplet storage and metabolism: from yeast to man. J Lipid Res (2011) 0.91
PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Mol Metab (2013) 0.90
The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism. J Biol Chem (2001) 0.89
Ulcerative dermatitis in C57BL/6 mice exhibits an oxidative stress response consistent with normal wound healing. Comp Med (2012) 0.89
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res (2012) 0.88
Clinical implications of positron emission tomography-negative residual computed tomography masses after chemotherapy for diffuse large B-cell lymphoma. Leuk Lymphoma (2013) 0.87
The impact of radiographic retropharyngeal adenopathy in oropharyngeal cancer. Cancer (2013) 0.86
Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR. Mol Cell Endocrinol (2005) 0.84
Follistatin promotes adipocyte differentiation, browning, and energy metabolism. J Lipid Res (2014) 0.83
AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes. Am J Perinatol (2008) 0.81
Management of the lymph node-positive neck in the patient with human papillomavirus-associated oropharyngeal cancer. Cancer (2014) 0.81
Localization and altered expression of AKR1C family members in human ovarian tissues. Mol Cell Probes (2005) 0.79
Hoofbeats, zebras, and insights into insulin resistance. J Clin Invest (2009) 0.79
Response to Pomozi et al's research commentary. Circ Res (2013) 0.79
Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells. Am J Physiol Gastrointest Liver Physiol (2003) 0.78
3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism. J Clin Endocrinol Metab (2008) 0.78
Lipin-1 flexes its muscle in autophagy. Cell Cycle (2014) 0.75
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest (2017) 0.75
Women in Metabolism: Part 3. Cell Metab (2015) 0.75
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J (2016) 0.75
Improved setup and positioning accuracy using a three-point customized cushion/mask/bite-block immobilization system for stereotactic reirradiation of head and neck cancer. J Appl Clin Med Phys (2016) 0.75