1
|
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.
|
Cell
|
2013
|
3.47
|
2
|
Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs.
|
Nat Genet
|
2005
|
1.51
|
3
|
Human sebaceous tumors harbor inactivating mutations in LEF1.
|
Nat Med
|
2006
|
1.40
|
4
|
Patched 1 conditional null allele in mice.
|
Genesis
|
2003
|
1.31
|
5
|
Heterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice.
|
PLoS Genet
|
2011
|
1.13
|
6
|
Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1.
|
J Med Genet
|
2011
|
1.11
|
7
|
Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice.
|
Dev Biol
|
2011
|
1.08
|
8
|
Spatial mapping and quantification of developmental branching morphogenesis.
|
Development
|
2012
|
1.07
|
9
|
Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.
|
PLoS Genet
|
2009
|
1.04
|
10
|
Let's stick together: the role of the Fras1 and Frem proteins in epidermal adhesion.
|
IUBMB Life
|
2007
|
1.00
|
11
|
Basement membranes in development and disease.
|
Birth Defects Res C Embryo Today
|
2010
|
0.99
|
12
|
Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis.
|
Dev Biol
|
2003
|
0.98
|
13
|
Expression of the fras1/frem gene family during zebrafish development and fin morphogenesis.
|
Dev Dyn
|
2008
|
0.91
|
14
|
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis.
|
PLoS Genet
|
2010
|
0.90
|
15
|
A breathtaking phenotype: unexpected roles of the DNA base damage response protein ASCIZ as a key regulator of early lung development.
|
Cell Cycle
|
2011
|
0.90
|
16
|
Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells.
|
Proc Natl Acad Sci U S A
|
2013
|
0.87
|
17
|
Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice.
|
Dis Model Mech
|
2013
|
0.84
|
18
|
In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci.
|
Mamm Genome
|
2015
|
0.79
|
19
|
Krt6a-Cre transgenic mice direct LoxP-mediated recombination to the companion cell layer of the hair follicle and following induction by retinoic acid to the interfollicular epidermis.
|
J Invest Dermatol
|
2004
|
0.75
|