PubRank

David W Litchfield

Author PubWeight™ 57.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell 2009 2.50
2 Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol Cell 2008 2.29
3 Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta 2007 2.07
4 A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood 2011 1.84
5 Order or chaos? An evaluation of the regulation of protein kinase CK2. Biochem Cell Biol 2004 1.41
6 Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling. Angew Chem Int Ed Engl 2010 1.37
7 The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta. Int J Biol Sci 2005 1.21
8 The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton. Cell Signal 2005 1.19
9 The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein. Mol Cell Biol 2005 1.18
10 The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2. J Biol Chem 2002 1.15
11 Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining. J Biol Chem 2010 1.14
12 Neurotransmitter modulation of small-conductance Ca2+-activated K+ channels by regulation of Ca2+ gating. Neuron 2008 1.11
13 A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems. Am J Hum Genet 2009 1.08
14 SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling. Brain 2010 1.06
15 The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein. J Biol Chem 2006 1.04
16 An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets. Mol Cell Proteomics 2008 1.04
17 Regulation of cell proliferation and survival: convergence of protein kinases and caspases. Biochim Biophys Acta 2009 1.02
18 Interactions between protein kinase CK2 and Pin1. Evidence for phosphorylation-dependent interactions. J Biol Chem 2002 1.01
19 Casein kinase 2 beta-subunit is a regulator of bone morphogenetic protein 2 signaling. Biophys J 2010 0.99
20 Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells. Cell Signal 2008 0.99
21 Phosphorylation regulates the stability of the regulatory CK2beta subunit. Oncogene 2002 0.99
22 The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane. J Biol Chem 2004 0.98
23 A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling. Sci Signal 2011 0.98
24 Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity. Biochem J 2003 0.95
25 Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. J Biol Chem 2012 0.94
26 Nuclear export of S6K1 II is regulated by protein kinase CK2 phosphorylation at Ser-17. J Biol Chem 2006 0.94
27 Evidence for regulation of mitotic progression through temporal phosphorylation and dephosphorylation of CK2alpha. Mol Cell Biol 2009 0.92
28 CK2 interacting proteins: emerging paradigms for CK2 regulation? Mol Cell Biochem 2005 0.92
29 Protein kinase CK2 is a constitutively active enzyme that promotes cell survival: strategies to identify CK2 substrates and manipulate its activity in mammalian cells. Methods Enzymol 2010 0.90
30 A novel costimulatory signaling in human T lymphocytes by a splice variant of CD28. Blood 2002 0.89
31 Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α': implications for pathological roles of CK2 in promoting cancer cell survival. Oncotarget 2013 0.88
32 Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2. Biochim Biophys Acta 2005 0.88
33 Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis. J Biol Chem 2013 0.87
34 Regulation of caspase pathways by protein kinase CK2: identification of proteins with overlapping CK2 and caspase consensus motifs. Mol Cell Biochem 2011 0.87
35 Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase. Nucleic Acids Res 2009 0.86
36 The emerging CK2 interactome: insights into the regulation and functions of CK2. Mol Cell Biochem 2008 0.85
37 Unbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of EEF1D as a substrate for CK2. J Proteome Res 2011 0.85
38 Versatile strategy for biochemical, electrochemical and immunoarray detection of protein phosphorylations. J Am Chem Soc 2012 0.84
39 The dual histidine motif in the active site of Pin1 has a structural rather than catalytic role. Biochemistry 2008 0.84
40 An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation. Mol Cell Proteomics 2014 0.84
41 Peptide biosensors for the electrochemical measurement of protein kinase activity. Anal Chem 2008 0.83
42 Development of an unbiased statistical method for the analysis of unigenic evolution. BMC Bioinformatics 2006 0.83
43 Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation. J Cell Sci 2010 0.83
44 Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1. J Med Chem 2011 0.82
45 Electrochemical investigations of Tau protein phosphorylations and interactions with Pin1. Chem Biodivers 2012 0.81
46 Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding. Front Physiol 2013 0.81
47 Flavin adenine dinucleotide content of quinone reductase 2: analysis and optimization for structure-function studies. Anal Biochem 2011 0.80
48 Localization of phosphorylated CK2alpha to the mitotic spindle requires the peptidyl-prolyl isomerase Pin1. J Cell Sci 2011 0.80
49 Interaction between CK2α and CK2β, the subunits of protein kinase CK2: thermodynamic contributions of key residues on the CK2α surface. Biochemistry 2010 0.80
50 Functional proteomics strategy for validation of protein kinase inhibitors reveals new targets for a TBB-derived inhibitor of protein kinase CK2. J Proteomics 2012 0.80
51 Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2. Biochem J 2005 0.80
52 CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. J Biol Chem 2011 0.80
53 Development of a stabilized form of the regulatory CK2beta subunit that inhibits cell proliferation. J Biol Chem 2007 0.80
54 Chemoproteomic characterization of protein kinase inhibitors using immobilized ATP. Methods Mol Biol 2012 0.78
55 Chemical proteomics and functional proteomics strategies for protein kinase inhibitor validation and protein kinase substrate identification: applications to protein kinase CK2. Biochim Biophys Acta 2013 0.77
56 "Going KiNativ": probing the Native Kinome. Chem Biol 2011 0.77
57 2-Triazenoazaindoles: α novel class of triazenes inducing transcriptional down-regulation of EGFR and HER-2 in human pancreatic cancer cells. Int J Oncol 2011 0.76