|
1
|
Reversible inactivation of the tumor suppressor PTEN by H2O2.
|
J Biol Chem
|
2002
|
5.08
|
|
2
|
Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling.
|
Cell
|
2010
|
3.82
|
|
3
|
Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function.
|
Cell
|
2004
|
3.65
|
|
4
|
Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation.
|
Science
|
2003
|
3.60
|
|
5
|
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors.
|
Proc Natl Acad Sci U S A
|
2004
|
3.49
|
|
6
|
Redox-based regulation of signal transduction: principles, pitfalls, and promises.
|
Free Radic Biol Med
|
2008
|
3.38
|
|
7
|
Inactivation of human peroxiredoxin I during catalysis as the result of the oxidation of the catalytic site cysteine to cysteine-sulfinic acid.
|
J Biol Chem
|
2002
|
2.68
|
|
8
|
Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine.
|
J Biol Chem
|
2004
|
2.32
|
|
9
|
Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II.
|
Nature
|
2005
|
2.29
|
|
10
|
Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression.
|
J Exp Med
|
2002
|
2.15
|
|
11
|
Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria.
|
J Biol Chem
|
2004
|
2.14
|
|
12
|
Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice.
|
Blood
|
2003
|
2.05
|
|
13
|
2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications.
|
Trends Mol Med
|
2005
|
2.02
|
|
14
|
Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence.
|
J Biol Chem
|
2003
|
1.90
|
|
15
|
Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins.
|
J Biol Chem
|
2004
|
1.86
|
|
16
|
Regulation of reactive oxygen species generation in cell signaling.
|
Mol Cells
|
2011
|
1.85
|
|
17
|
Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.
|
Mol Cell Biol
|
2004
|
1.82
|
|
18
|
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage.
|
Cell Metab
|
2012
|
1.65
|
|
19
|
Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.
|
J Biol Chem
|
2002
|
1.61
|
|
20
|
Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation.
|
J Biol Chem
|
2002
|
1.54
|
|
21
|
Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1.
|
Proc Natl Acad Sci U S A
|
2005
|
1.53
|
|
22
|
Molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin.
|
J Biol Chem
|
2006
|
1.52
|
|
23
|
Sestrin 2 is not a reductase for cysteine sulfinic acid of peroxiredoxins.
|
Antioxid Redox Signal
|
2009
|
1.39
|
|
24
|
Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria.
|
Mol Cell
|
2012
|
1.34
|
|
25
|
Irreversible oxidation of the active-site cysteine of peroxiredoxin to cysteine sulfonic acid for enhanced molecular chaperone activity.
|
J Biol Chem
|
2008
|
1.27
|
|
26
|
Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin.
|
J Biol Chem
|
2009
|
1.25
|
|
27
|
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
|
Mol Cell Biol
|
2004
|
1.17
|
|
28
|
Irreversible inactivation of glutathione peroxidase 1 and reversible inactivation of peroxiredoxin II by H2O2 in red blood cells.
|
Antioxid Redox Signal
|
2010
|
1.15
|
|
29
|
Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha.
|
J Biol Chem
|
2003
|
1.14
|
|
30
|
Sulfiredoxin Translocation into Mitochondria Plays a Crucial Role in Reducing Hyperoxidized Peroxiredoxin III.
|
J Biol Chem
|
2009
|
1.11
|
|
31
|
Mechanism of tyrosine phosphorylation and activation of phospholipase C-gamma 1. Tyrosine 783 phosphorylation is not sufficient for lipase activation.
|
J Biol Chem
|
2004
|
1.11
|
|
32
|
Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression.
|
Free Radic Biol Med
|
2012
|
1.11
|
|
33
|
Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression.
|
Antioxid Redox Signal
|
2011
|
1.11
|
|
34
|
Activity assay of mammalian 2-cys peroxiredoxins using yeast thioredoxin reductase system.
|
Anal Biochem
|
2005
|
1.09
|
|
35
|
Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.
|
Antioxid Redox Signal
|
2012
|
1.09
|
|
36
|
Laminar shear stress up-regulates peroxiredoxins (PRX) in endothelial cells: PRX 1 as a mechanosensitive antioxidant.
|
J Biol Chem
|
2007
|
1.08
|
|
37
|
Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function.
|
J Biol Chem
|
2003
|
1.08
|
|
38
|
Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice.
|
Circ Res
|
2011
|
1.08
|
|
39
|
Membrane targeting of C2 domains of phospholipase C-delta isoforms.
|
J Biol Chem
|
2001
|
1.07
|
|
40
|
Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver.
|
Hepatology
|
2011
|
1.05
|
|
41
|
Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.
|
J Biol Chem
|
2003
|
1.04
|
|
42
|
Glutathionylation of peroxiredoxin I induces decamer to dimers dissociation with concomitant loss of chaperone activity.
|
Biochemistry
|
2011
|
1.02
|
|
43
|
Mutagenesis and modeling of the peroxiredoxin (Prx) complex with the NMR structure of ATP-bound human sulfiredoxin implicate aspartate 187 of Prx I as the catalytic residue in ATP hydrolysis.
|
Biochemistry
|
2006
|
1.01
|
|
44
|
Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase.
|
J Biol Chem
|
2007
|
1.01
|
|
45
|
Ahnak protein activates protein kinase C (PKC) through dissociation of the PKC-protein phosphatase 2A complex.
|
J Biol Chem
|
2008
|
0.98
|
|
46
|
Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha.
|
J Biol Chem
|
2008
|
0.98
|
|
47
|
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.
|
Biochem J
|
2004
|
0.96
|
|
48
|
AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C.
|
J Biol Chem
|
2004
|
0.96
|
|
49
|
B- to plasma-cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses.
|
Antioxid Redox Signal
|
2010
|
0.93
|
|
50
|
Induction of sulfiredoxin via an Nrf2-dependent pathway and hyperoxidation of peroxiredoxin III in the lungs of mice exposed to hyperoxia.
|
Antioxid Redox Signal
|
2009
|
0.93
|
|
51
|
Redox regulation of lipopolysaccharide-mediated sulfiredoxin induction, which depends on both AP-1 and Nrf2.
|
J Biol Chem
|
2010
|
0.91
|
|
52
|
Sulfiredoxin protein is critical for redox balance and survival of cells exposed to low steady-state levels of H2O2.
|
J Biol Chem
|
2011
|
0.91
|
|
53
|
Peroxiredoxin II is essential for preventing hemolytic anemia from oxidative stress through maintaining hemoglobin stability.
|
Biochem Biophys Res Commun
|
2012
|
0.90
|
|
54
|
An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells.
|
Cancer Lett
|
2011
|
0.89
|
|
55
|
Hydroxyurea-induced expression of glutathione peroxidase 1 in red blood cells of individuals with sickle cell anemia.
|
Antioxid Redox Signal
|
2010
|
0.88
|
|
56
|
Peroxiredoxin III and sulfiredoxin together protect mice from pyrazole-induced oxidative liver injury.
|
Antioxid Redox Signal
|
2012
|
0.88
|
|
57
|
Measuring H2O2 produced in response to cell surface receptor activation.
|
Nat Chem Biol
|
2007
|
0.87
|
|
58
|
Structural basis of cellular redox regulation by human TRP14.
|
J Biol Chem
|
2004
|
0.84
|
|
59
|
ERp16, an endoplasmic reticulum-resident thiol-disulfide oxidoreductase: biochemical properties and role in apoptosis induced by endoplasmic reticulum stress.
|
J Biol Chem
|
2008
|
0.84
|
|
60
|
The RING-H2-finger protein APC11 as a target of hydrogen peroxide.
|
Free Radic Biol Med
|
2004
|
0.84
|
|
61
|
Oxidation of proteinaceous cysteine residues by dopamine-derived H2O2 in PC12 cells.
|
Arch Biochem Biophys
|
2002
|
0.84
|
|
62
|
Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody.
|
Proc Natl Acad Sci U S A
|
2014
|
0.83
|
|
63
|
Identification and characterization of alternatively transcribed form of peroxiredoxin IV gene that is specifically expressed in spermatids of postpubertal mouse testis.
|
J Biol Chem
|
2011
|
0.82
|
|
64
|
Thioredoxin-related protein 14, a new member of the thioredoxin family with disulfide reductase activity: implication in the redox regulation of TNF-alpha signaling.
|
Free Radic Biol Med
|
2009
|
0.82
|
|
65
|
Identification of phospholipase C-gamma1 as a mitogen-activated protein kinase substrate.
|
J Biol Chem
|
2004
|
0.80
|
|
66
|
Protective role of cytosolic 2-cys peroxiredoxin in the TNF-alpha-induced apoptotic death of human cancer cells.
|
Free Radic Biol Med
|
2009
|
0.80
|
|
67
|
Dominant role of peroxiredoxin/JNK axis in stemness regulation during neurogenesis from embryonic stem cells.
|
Stem Cells
|
2014
|
0.80
|
|
68
|
Phospholipase C-delta1 rescues intracellular Ca2+ overload in ischemic heart and hypoxic neonatal cardiomyocytes.
|
J Steroid Biochem Mol Biol
|
2004
|
0.79
|
|
69
|
Annexin A2-S100A10 heterotetramer, a novel substrate of thioredoxin.
|
J Biol Chem
|
2005
|
0.79
|
|
70
|
1H, 15N, and 13C chemical shift assignments of the human Sulfiredoxin (hSrx).
|
J Biomol NMR
|
2005
|
0.78
|
|
71
|
A fluorescence turn-on H2O2 probe exhibits lysosome-localized fluorescence signals.
|
Chem Commun (Camb)
|
2012
|
0.77
|
|
72
|
A colorimetric assay for sulfiredoxin activity using inorganic phosphate measurement.
|
Anal Biochem
|
2009
|
0.77
|
|
73
|
Antibodies against non-immunizing antigens derived from a large immune scFv library.
|
Mol Cells
|
2011
|
0.76
|
|
74
|
Study of the signaling function of sulfiredoxin and peroxiredoxin III in isolated adrenal gland: unsuitability of clonal and primary adrenocortical cells.
|
Methods Enzymol
|
2013
|
0.75
|
|
75
|
Impaired antigen receptor induced calcium mobilization in a phospholipase C-gamma1 deficient B cell line.
|
Immunol Lett
|
2003
|
0.75
|