Published in J Biol Chem on July 25, 1990
DNA end-joining catalyzed by human cell-free extracts. Proc Natl Acad Sci U S A (1998) 3.11
Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1990) 2.15
Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I. Mol Cell Biol (1994) 1.76
An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol Cell Biol (1997) 1.71
In vitro mutagenesis and functional expression in Escherichia coli of a cDNA encoding the catalytic domain of human DNA ligase I. Nucleic Acids Res (1991) 1.68
The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication. EMBO J (1995) 1.59
PCNA binding proteins in Drosophila melanogaster : the analysis of a conserved PCNA binding domain. Nucleic Acids Res (1998) 1.32
Activation of mammalian DNA ligase I through phosphorylation by casein kinase II. EMBO J (1992) 1.29
Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents. EMBO J (1991) 1.19
De novo synthesis of budding yeast DNA polymerase alpha and POL1 transcription at the G1/S boundary are not required for entrance into S phase. Proc Natl Acad Sci U S A (1993) 1.12
DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates. PLoS One (2013) 1.02
DNA ligase I is associated with the 21 S complex of enzymes for DNA synthesis in HeLa cells. Nucleic Acids Res (1994) 0.98
Cellular DNA ligase I is recruited to cytoplasmic vaccinia virus factories and masks the role of the vaccinia ligase in viral DNA replication. Cell Host Microbe (2009) 0.96
DNA ligase I gene expression during differentiation and cell proliferation. Nucleic Acids Res (1992) 0.96
DNA ligase I from Xenopus laevis eggs. Nucleic Acids Res (1991) 0.95
Identification of a specific inhibitor for DNA ligase I in human cells. Proc Natl Acad Sci U S A (1992) 0.89
Structure of the human DNA ligase I gene. Nucleic Acids Res (1992) 0.89
Purification and characterization of DNA ligase I from the trypanosomatid Crithidia fasciculata. Nucleic Acids Res (1992) 0.86
My journey to DNA repair. Genomics Proteomics Bioinformatics (2012) 0.81
DNA ligase I, the replicative DNA ligase. Subcell Biochem (2012) 0.79
Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair. J Biol Chem (2012) 0.78
Rate of depurination of native deoxyribonucleic acid. Biochemistry (1972) 10.85
DNA glycosylases, endonucleases for apurinic/apyrimidinic sites, and base excision-repair. Prog Nucleic Acid Res Mol Biol (1979) 8.01
Covalently closed circular duplex DNA of Epstein-Barr virus in a human lymphoid cell line. J Mol Biol (1976) 7.42
DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli. J Biol Chem (1977) 7.24
DNA repair enzymes. Annu Rev Biochem (1982) 6.68
Human DNA repair genes. Science (2001) 6.11
Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry (1974) 5.70
Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid. Biochemistry (1972) 5.49
Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas. Proc Natl Acad Sci U S A (1974) 5.13
Role of poly(ADP-ribose) formation in DNA repair. Nature (1992) 4.98
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. EMBO J (1996) 4.89
An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc Natl Acad Sci U S A (1974) 4.40
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci U S A (1999) 4.28
Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts. Cell (1988) 4.28
Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue. J Biol Chem (1980) 4.16
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J (1997) 3.96
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr Biol (1999) 3.47
Recovery of antediluvian DNA. Nature (1993) 3.37
Epstein-Barr virus genomes with properties of circular DNA molecules in carrier cells. Proc Natl Acad Sci U S A (1975) 3.26
Specific cleavage of model recombination and repair intermediates by the yeast Rad1-Rad10 DNA endonuclease. Science (1994) 3.16
Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents. Nature (1982) 3.11
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol Cell (2001) 3.07
DNA glycosylase activities for thymine residues damaged by ring saturation, fragmentation, or ring contraction are functions of endonuclease III in Escherichia coli. J Biol Chem (1984) 3.06
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis. Proc Natl Acad Sci U S A (1985) 3.01
Renaturation of transfer ribonucleic acids through site binding of magnesium. Proc Natl Acad Sci U S A (1966) 2.85
Molecular cloning of the complete Epstein-Barr virus genome as a set of overlapping restriction endonuclease fragments. Nucleic Acids Res (1981) 2.83
Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA. Nature (1979) 2.81
Relationship between Epstein-Barr virus (EBV) DNA and the EBV-determined nuclear antigen (EBNA) in Burkitt lymphoma biopsies and other lymphoproliferative malignancies. Int J Cancer (1974) 2.80
Tertiary structure in transfer ribonucleic acids. Cold Spring Harb Symp Quant Biol (1966) 2.80
New class of enzymes acting on damaged DNA. Nature (1976) 2.79
Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli. Nucleic Acids Res (1979) 2.79
The intracellular signal for induction of resistance to alkylating agents in E. coli. Cell (1986) 2.77
Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli. EMBO J (1984) 2.77
Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J (1998) 2.68
Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. EMBO J (1982) 2.67
Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in malignant epithelial cells from patients with poorly differentiated carcinoma of the nasopharynx. Proc Natl Acad Sci U S A (1974) 2.66
A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev (1997) 2.61
Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase. J Biol Chem (1982) 2.56
Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication. Mol Cell (2000) 2.54
Generation of single-nucleotide repair patches following excision of uracil residues from DNA. Mol Cell Biol (1992) 2.53
Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. J Biol Chem (1998) 2.49
XRCC1 protein interacts with one of two distinct forms of DNA ligase III. Biochemistry (1997) 2.46
Sequence complexity of circular Epstein-Bar virus DNA in transformed cells. J Virol (1981) 2.43
Properties of 3-methyladenine-DNA glycosylase from Escherichia coli. Biochemistry (1978) 2.37
Methyl methane sulfonate-sensitive mutant of Escherichia coli deficient in an endonuclease specific for apurinic sites in deoxyribonucleic acid. J Bacteriol (1976) 2.37
Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase. J Mol Biol (1980) 2.32
Location of the active site for enzyme-adenylate formation in DNA ligases. Proc Natl Acad Sci U S A (1991) 2.32
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase. Proc Natl Acad Sci U S A (1997) 2.27
Linear association between cellular DNA and Epstein-Barr virus DNA in a human lymphoblastoid cell line. Proc Natl Acad Sci U S A (1973) 2.27
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. J Biol Chem (2000) 2.25
Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells. Proc Natl Acad Sci U S A (2000) 2.24
Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1990) 2.15
Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage. EMBO J (1984) 2.15
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents. Cell (1992) 2.13
Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis. J Biol Chem (1996) 2.10
Intracellular forms of Epstein-Barr virus DNA in human tumour cells in vivo. Nature (1976) 2.10
Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I. J Biol Chem (1994) 2.04
A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein. EMBO J (1999) 2.04
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase. EMBO J (1982) 2.03
Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J (1998) 2.03
Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli. Nucleic Acids Res (1985) 2.00
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc Natl Acad Sci U S A (1997) 1.89
Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution. Biochemistry (1973) 1.88
Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase. EMBO J (2001) 1.85
Mammalian DNA ligases. Catalytic domain and size of DNA ligase I. J Biol Chem (1990) 1.84
Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues. J Biol Chem (1978) 1.84
An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining. Proc Natl Acad Sci U S A (1997) 1.82
Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA. EMBO J (1991) 1.80
Three distinct DNA ligases in mammalian cells. J Biol Chem (1991) 1.79
Sites of sequence variability in Epstein-Barr virus DNA from different sources. Proc Natl Acad Sci U S A (1979) 1.78
Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair. Curr Biol (2000) 1.78
Circular Epstein-Barr virus genomes of reduced size in a human lymphoid cell line of infectious mononucleosis origin. J Virol (1977) 1.77
Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I. Mol Cell Biol (1994) 1.76
An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol Cell Biol (1997) 1.71
DNA ligase I deficiency in Bloom's syndrome. Nature (1987) 1.70
Reconstitution of the DNA base excision-repair pathway. Curr Biol (1994) 1.68
In vitro mutagenesis and functional expression in Escherichia coli of a cDNA encoding the catalytic domain of human DNA ligase I. Nucleic Acids Res (1991) 1.68
Defective processing of methylated single-stranded DNA by E. coli AlkB mutants. Genes Dev (2000) 1.68
Human lymphoblastoid cell lines derived from individuals without lymphoproliferative disease contain the same latent forms of Epstein-Barr virus DNA as those found in tumor cells. Int J Cancer (1977) 1.67
Epstein-Barr virus DNA in human lymphoid cell lines: in vitro conversion. Virology (1976) 1.67
Base excision repair of oxidative DNA damage activated by XPG protein. Mol Cell (1999) 1.67
DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III. J Biol Chem (1999) 1.66
DNA deoxyribophosphodiesterase. EMBO J (1988) 1.66
Purification of the Epstein-Barr virus-determined nuclear antigen from Epstein-Barr virus-transformed human lymphoid cell lines. J Virol (1978) 1.65
Conformational differences between the biologically active and inactive forms of a transfer ribonucleic acid. Proc Natl Acad Sci U S A (1967) 1.64
DNA ligase IV from HeLa cell nuclei. J Biol Chem (1996) 1.64
Repair and recombination. How to make ends meet. Curr Biol (1995) 1.64
Hypoxanthine in deoxyribonucleic acid: generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus. Biochemistry (1980) 1.59
Functional domains and methyl acceptor sites of the Escherichia coli ada protein. J Biol Chem (1988) 1.58
Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination. J Biol Chem (1995) 1.57
Properties of deoxyribonuclease 3 from mammalian tissues. J Biol Chem (1969) 1.55
O6-Methylguanine-DNA methyltransferase of human lymphoid cells: structural and kinetic properties and absence in repair-deficient cells. Cancer Res (1983) 1.52
Thymine lesions produced by ionizing radiation in double-stranded DNA. Biochemistry (1985) 1.51
Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination. Mol Cell Biol (1995) 1.51
NAD(+)-dependent repair of damaged DNA by human cell extracts. J Biol Chem (1993) 1.50
A mammalian endonuclease specific for apurinic sites in double-stranded deoxyribonucleic acid. I. Purification and general properties. J Biol Chem (1974) 1.49
DNA methylation and control of gene expression. Nature (1981) 1.46