Published in J Lipid Res on October 06, 2011
HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism. Hum Mol Genet (2013) 0.93
Role of precursor mRNA splicing in nutrient-induced alterations in gene expression and metabolism. J Nutr (2015) 0.79
Alternative splicing in the regulation of cholesterol homeostasis. Curr Opin Lipidol (2013) 0.78
Desaturase and elongase-limiting endogenous long-chain polyunsaturated fatty acid biosynthesis. Curr Opin Clin Nutr Metab Care (2016) 0.77
Regulation of alternative splicing in obesity and weight loss. Adipocyte (2013) 0.76
Age and haplotype variations within FADS1 interact and associate with alterations in fatty acid composition in human male cortical brain tissue. PLoS One (2012) 0.76
The emerging role of alternative splicing in senescence and aging. Aging Cell (2017) 0.75
Alternative RNA Splicing in the Pathogenesis of Liver Disease. Front Endocrinol (Lausanne) (2017) 0.75
Fads3 modulates docosahexaenoic acid in liver and brain. Prostaglandins Leukot Essent Fatty Acids (2017) 0.75
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Comparative aspects of the brain growth spurt. Early Hum Dev (1979) 6.96
Function of alternative splicing. Gene (2004) 5.95
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA (2006) 4.72
Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet (2006) 4.13
ASD: a bioinformatics resource on alternative splicing. Nucleic Acids Res (2006) 3.60
Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1. Mol Cell (2007) 3.22
The opposing effects of n-3 and n-6 fatty acids. Prog Lipid Res (2007) 2.94
Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase. J Biol Chem (1999) 2.49
FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. Am J Clin Nutr (2008) 2.42
Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proc Natl Acad Sci U S A (2007) 2.32
A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia. PLoS Genet (2009) 2.24
Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale. Biochimie (2009) 2.24
Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein. Biochem Soc Trans (2008) 2.12
Tissue levels of polyunsaturated fatty acids during early human development. J Pediatr (1992) 1.80
Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis. Nat Cell Biol (2004) 1.79
Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet (2009) 1.77
Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro. Oncogene (2007) 1.77
One-step lipid extraction and fatty acid methyl esters preparation from fresh plant tissues. Anal Biochem (1993) 1.73
Regulation of alternative splicing: more than just the ABCs. J Biol Chem (2007) 1.71
The influence of moderate and high dietary long chain polyunsaturated fatty acids (LCPUFA) on baboon neonate tissue fatty acids. Pediatr Res (2007) 1.61
Reduced G protein-coupled signaling efficiency in retinal rod outer segments in response to n-3 fatty acid deficiency. J Biol Chem (2004) 1.56
The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system. BMC Med (2005) 1.41
Association of fatty acid desaturase genes with attention-deficit/hyperactivity disorder. Biol Psychiatry (2006) 1.33
Acetonitrile chemical ionization tandem mass spectrometry to locate double bonds in polyunsaturated fatty acid methyl esters. Anal Chem (1999) 1.20
hnRNP I/PTB can antagonize the splicing repressor activity of SRp30c. RNA (2007) 1.19
A polypyrimidine/polypurine tract within the Hmga2 minimal promoter: a common feature of many growth-related genes. Biochemistry (2002) 1.14
Genotype-specific responses in Atlantic salmon (Salmo salar) subject to dietary fish oil replacement by vegetable oil: a liver transcriptomic analysis. BMC Genomics (2011) 1.13
Serial analysis of gene expression in mouse uterus at the implantation site. J Biol Chem (2006) 1.11
Novel fatty acid desaturase 3 (FADS3) transcripts generated by alternative splicing. Gene (2009) 1.10
Acetonitrile covalent adduct chemical ionization mass spectrometry for double bond localization in non-methylene-interrupted polyene fatty acid methyl esters. Anal Chem (2006) 1.05
The same rat Delta6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis. Biochem J (2002) 1.04
The influence of dietary docosahexaenoic acid and arachidonic acid on central nervous system polyunsaturated fatty acid composition. Prostaglandins Leukot Essent Fatty Acids (2007) 1.03
Double bond localization in minor homoallylic fatty acid methyl esters using acetonitrile chemical ionization tandem mass spectrometry. Anal Biochem (2002) 0.95
Alternative transcripts of fatty acid desaturase (FADS) genes. Prostaglandins Leukot Essent Fatty Acids (2010) 0.94
Alternative splicing generates a novel FADS2 alternative transcript in baboons. Mol Biol Rep (2009) 0.94
FADS2 polymorphisms modify the effect of breastfeeding on child IQ. PLoS One (2010) 0.94
Changes induced by dietary energy intake and divergent selection for muscle fat content in rainbow trout (Oncorhynchus mykiss), assessed by transcriptome and proteome analysis of the liver. BMC Genomics (2008) 0.93
Dietary rapeseed oil affects the expression of genes involved in hepatic lipid metabolism in Atlantic salmon (Salmo salar L.). J Nutr (2005) 0.90
Biosynthesis of docosahexaenoic acid in human cells: evidence that two different delta 6-desaturase activities may exist. Biochim Biophys Acta (1996) 0.86
Dietary docosahexaenoic acid but not arachidonic acid influences central nervous system fatty acid status in baboon neonates. Prostaglandins Leukot Essent Fatty Acids (2009) 0.82
Evidence of isozymes for delta6 fatty acid desaturase in rat hepatocytes. Biosci Biotechnol Biochem (2003) 0.80
Atherosclerosis: the eicosanoid connection. Mol Cell Biochem (1992) 0.78
Clinical correlates in an experimental model of repetitive mild brain injury. Ann Neurol (2013) 2.32
Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates. Pediatr Res (2002) 1.82
Increasing recovery time between injuries improves cognitive outcome after repetitive mild concussive brain injuries in mice. Neurosurgery (2012) 1.81
Dietary fat intakes for pregnant and lactating women. Br J Nutr (2007) 1.80
The influence of moderate and high dietary long chain polyunsaturated fatty acids (LCPUFA) on baboon neonate tissue fatty acids. Pediatr Res (2007) 1.61
Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration. J Lipid Res (2009) 1.59
Clinical significance of framingham risk score, flow-mediated dilation and pulse wave velocity in patients with stable angina. Circ J (2011) 1.47
An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Delta8-desaturates 20:2n-6 and 20:3n-3. J Lipid Res (2009) 1.42
The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system. BMC Med (2005) 1.41
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. PLoS One (2012) 1.27
Decreased depression up to one year following CBSM+ intervention in depressed women with AIDS: the smart/EST women's project. J Health Psychol (2005) 1.15
Dual origin of the renal tubules in Drosophila: mesodermal cells integrate and polarize to establish secretory function. Curr Biol (2003) 1.12
Novel fatty acid desaturase 3 (FADS3) transcripts generated by alternative splicing. Gene (2009) 1.10
Branched chain fatty acids reduce the incidence of necrotizing enterocolitis and alter gastrointestinal microbial ecology in a neonatal rat model. PLoS One (2011) 1.08
Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab (2011) 1.06
Low-level laser light therapy improves cognitive deficits and inhibits microglial activation after controlled cortical impact in mice. J Neurotrauma (2011) 1.06
Acetonitrile covalent adduct chemical ionization mass spectrometry for double bond localization in non-methylene-interrupted polyene fatty acid methyl esters. Anal Chem (2006) 1.05
Omega-3 fatty acids, energy substrates, and brain function during aging. Prostaglandins Leukot Essent Fatty Acids (2006) 1.02
MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr (2010) 1.01
Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice. J Cereb Blood Flow Metab (2010) 1.00
Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts. Prostaglandins Leukot Essent Fatty Acids (2012) 0.99
Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice. J Nutr (2011) 0.98
Branched chain fatty acids are constituents of the normal healthy newborn gastrointestinal tract. Pediatr Res (2008) 0.98
A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids. J Lipid Res (2012) 0.97
The influence of maternal early to mid-gestation nutrient restriction on long chain polyunsaturated fatty acids in fetal sheep. Lipids (2008) 0.97
Formula feeding potentiates docosahexaenoic and arachidonic acid biosynthesis in term and preterm baboon neonates. J Lipid Res (2003) 0.96
Double bond localization in minor homoallylic fatty acid methyl esters using acetonitrile chemical ionization tandem mass spectrometry. Anal Biochem (2002) 0.95
Alternative transcripts of fatty acid desaturase (FADS) genes. Prostaglandins Leukot Essent Fatty Acids (2010) 0.94
Alternative splicing generates a novel FADS2 alternative transcript in baboons. Mol Biol Rep (2009) 0.94
Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab (2010) 0.93
Plasma incorporation, apparent retroconversion and β-oxidation of 13C-docosahexaenoic acid in the elderly. Nutr Metab (Lond) (2011) 0.93
The influence of prematurity and long chain polyunsaturate supplementation in 4-week adjusted age baboon neonate brain and related tissues. Pediatr Res (2003) 0.92
FADS2 function loss at the cancer hotspot 11q13 locus diverts lipid signaling precursor synthesis to unusual eicosanoid fatty acids. PLoS One (2011) 0.92
Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas. PLoS One (2007) 0.91
Noncontact binocular eye-gaze tracking for point-of-gaze estimation in three dimensions. IEEE Trans Biomed Eng (2008) 0.91
Dose-response effects of betamethasone on maturation of the fetal sheep lung. Am J Obstet Gynecol (2009) 0.90
Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. Lipids (2012) 0.90
Identification and characterization of conjugated fatty acid methyl esters of mixed double bond geometry by acetonitrile chemical ionization tandem mass spectrometry. Anal Chem (2003) 0.90
Electron transfer dissociation of doubly sodiated glycerophosphocholine lipids. J Am Soc Mass Spectrom (2007) 0.89
Individual trans octadecenoic acids and partially hydrogenated vegetable oil differentially affect hepatic lipid and lipoprotein metabolism in golden Syrian hamsters. J Nutr (2008) 0.89
Docosahexaenoic and arachidonic acid influence on preterm baboon retinal composition and function. Invest Ophthalmol Vis Sci (2003) 0.88
Altered cholesterol and fatty acid metabolism in Huntington disease. J Clin Lipidol (2010) 0.88
Steroid isotopic standards for gas chromatography-combustion isotope ratio mass spectrometry (GCC-IRMS). Steroids (2008) 0.88
Pomegranate seed oil reduces intestinal damage in a rat model of necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol (2012) 0.88
Alterations in arterial function after high-voltage electrical injury. Crit Care (2012) 0.88
Omega-3 fatty acid supplementation and cardiovascular disease events. JAMA (2013) 0.88
Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women. Am J Clin Nutr (2013) 0.87
Significant utilization of dietary arachidonic acid is for brain adrenic acid in baboon neonates. J Lipid Res (2002) 0.87
Characterization of cis-9 trans-11 trans-15 C18:3 in milk fat by GC and covalent adduct chemical ionization tandem MS. J Lipid Res (2009) 0.87
Straight-chain acyl-CoA oxidase knockout mouse accumulates extremely long chain fatty acids from alpha-linolenic acid: evidence for runaway carousel-type enzyme kinetics in peroxisomal beta-oxidation diseases. Mol Genet Metab (2002) 0.87
Differential tissue dose responses of (n-3) and (n-6) PUFA in neonatal piglets fed docosahexaenoate and arachidonoate. J Nutr (2007) 0.87
Mice lacking FABP9/PERF15 develop sperm head abnormalities but are fertile. Dev Biol (2010) 0.86
Detrimental effect of genetic inhibition of B-site APP-cleaving enzyme 1 on functional outcome after controlled cortical impact in young adult mice. J Neurotrauma (2011) 0.86
Kollidon VA64, a membrane-resealing agent, reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab (2011) 0.86
Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin. Prostaglandins Leukot Essent Fatty Acids (2012) 0.85
Influence of dietary long-chain PUFA on premature baboon lung FA and dipalmitoyl PC composition. Lipids (2003) 0.84
Dietary arachidonic acid and docosahexaenoic acid regulate liver fatty acid desaturase (FADS) alternative transcript expression in suckling piglets. Prostaglandins Leukot Essent Fatty Acids (2013) 0.83
Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets. J Lipid Res (2014) 0.83
High-Oleic Ready-to-Use Therapeutic Food Maintains Docosahexaenoic Acid Status in Severe Malnutrition. J Pediatr Gastroenterol Nutr (2015) 0.83
Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets. J Lipid Res (2013) 0.83
Combined treatment with compression therapy and ablation of incompetent superficial and perforating veins reduces ulcer recurrence in patients with CEAP 5 venous disease. J Vasc Surg (2011) 0.82
Dietary docosahexaenoic acid but not arachidonic acid influences central nervous system fatty acid status in baboon neonates. Prostaglandins Leukot Essent Fatty Acids (2009) 0.82
Growth, clinical chemistry and immune function in domestic piglets fed varying ratios of arachidonic acid and DHA. Br J Nutr (2011) 0.82
Standardization is superior to traditional methods of teaching open vascular simulation. J Vasc Surg (2010) 0.81
Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man. Br J Nutr (2006) 0.81
The combination of EPA+DHA and low-dose aspirin ingestion reduces platelet function acutely whereas each alone may not in healthy humans. Prostaglandins Leukot Essent Fatty Acids (2012) 0.81
Heart arachidonic acid is uniquely sensitive to dietary arachidonic acid and docosahexaenoic acid content in domestic piglets. Prostaglandins Leukot Essent Fatty Acids (2011) 0.81
Application of comprehensive two-dimensional gas chromatography to sterols analysis. J Chromatogr A (2008) 0.81
One-step needle pose estimation for ultrasound guided biopsies. Conf Proc IEEE Eng Med Biol Soc (2007) 0.81