Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing.

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Published in RNA on May 08, 2006

Authors

Aimee L Jackson1, Julja Burchard, Devin Leake, Angela Reynolds, Janell Schelter, Jie Guo, Jason M Johnson, Lee Lim, Jon Karpilow, Kim Nichols, William Marshall, Anastasia Khvorova, Peter S Linsley

Author Affiliations

1: Rosetta Inpharmatics, LLC, Seattle, WA 98109, USA. aimee_jackson@merck.com

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