Published in PLoS Genet on September 29, 2011
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BMP signaling positively regulates Nodal expression during left right specification in the chick embryo. Development (2002) 0.96
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BMP2 is a positive regulator of Nodal signaling during left-right axis formation in the chicken embryo. Development (2002) 0.91
Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development. Dev Dyn (2008) 0.91
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Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling. J Cell Biol (2012) 2.12
The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol (2007) 2.10
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Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. Development (2009) 1.93
Cyclic nucleotide analogs as probes of signaling pathways. Nat Methods (2008) 1.84
Early endocardial morphogenesis requires Scl/Tal1. PLoS Genet (2007) 1.73
Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3. Structure (2008) 1.72
Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol (2007) 1.58
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells. Circulation (2007) 1.57
Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model. BMC Cancer (2009) 1.47
A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation. Mol Cell Biol (2006) 1.45
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer. J Clin Invest (2012) 1.43
cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells. J Physiol (2006) 1.36
8-pCPT-2'-O-Me-cAMP-AM: an improved Epac-selective cAMP analogue. Chembiochem (2008) 1.32
AF6 negatively regulates Rap1-induced cell adhesion. J Biol Chem (2005) 1.24
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex. Dev Biol (2008) 1.22
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Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis. Cell (2013) 1.21
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Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol (2010) 1.18
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Direct spatial control of Epac1 by cyclic AMP. Mol Cell Biol (2009) 1.17
Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum. J Biol Chem (2006) 1.14
Dominant-negative ALK2 allele associates with congenital heart defects. Circulation (2009) 1.14
The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions. Cell Signal (2008) 1.11
Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation. Dev Biol (2008) 1.11
Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation. Biol Open (2012) 1.10
Zebrafish cypher is important for somite formation and heart development. Dev Biol (2006) 1.10
CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function. J Cell Sci (2010) 1.08
MicroRNA-23 restricts cardiac valve formation by inhibiting Has2 and extracellular hyaluronic acid production. Circ Res (2011) 1.07
Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis. J Biol Chem (2009) 1.06
Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control. Cell Signal (2011) 1.03
Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. Biochim Biophys Acta (2003) 1.02
Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs. EMBO Rep (2007) 1.01
Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. Dev Biol (2007) 0.99
Identification and functional characterization of cardiac pacemaker cells in zebrafish. PLoS One (2012) 0.99
Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins. Mol Cell Biol (2010) 0.98
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A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected]. Mol Biol Cell (2010) 0.96
Structural dynamics in the activation of Epac. J Biol Chem (2007) 0.96
Wnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2. Birth Defects Res A Clin Mol Teratol (2011) 0.96
The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity. J Cell Biol (2011) 0.94
Identification and regulation of a molecular module for bleb-based cell motility. Dev Cell (2012) 0.94
Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development. Development (2011) 0.93
The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner. Cell Signal (2007) 0.92
Bmp signaling exerts opposite effects on cardiac differentiation. Circ Res (2012) 0.92
A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality. Nat Commun (2013) 0.90
Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein. J Mol Biol (2003) 0.86
ALK2 mutation in a patient with Down's syndrome and a congenital heart defect. Eur J Hum Genet (2011) 0.86
UDP-glucose dehydrogenase polymorphisms from patients with congenital heart valve defects disrupt enzyme stability and quaternary assembly. J Biol Chem (2012) 0.84
Fgf signaling induces posterior neuroectoderm independently of Bmp signaling inhibition. Dev Dyn (2004) 0.84
Revealing details: whole mount microRNA in situ hybridization protocol for zebrafish embryos and adult tissues. Biol Open (2012) 0.83
Rap1 and Rap2 antagonistically control endothelial barrier resistance. PLoS One (2013) 0.83
Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish. Development (2014) 0.83
Hyaluronan: a critical regulator of endothelial-to-mesenchymal transition during cardiac valve formation. Trends Cardiovasc Med (2013) 0.82
On the robustness of germ cell migration and microRNA-mediated regulation of chemokine signaling. Nat Genet (2013) 0.82
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Phylogeny of the CDC25 homology domain reveals rapid differentiation of Ras pathways between early animals and fungi. Cell Signal (2009) 0.82
Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22. Biochim Biophys Acta (2011) 0.82
The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex. J Biol Chem (2013) 0.81
Genetics of congenital heart defects: a candidate gene approach. Trends Cardiovasc Med (2010) 0.81
Signal transduction: thumbs up for inactivation. Nature (2004) 0.78
Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. ACS Chem Biol (2014) 0.77
GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability. Am J Hum Genet (2016) 0.76
Biochemistry of the Rap-specific guanine nucleotide exchange factors PDZ-GEF1 and -2. Methods Enzymol (2006) 0.76
The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster. PLoS One (2010) 0.75
Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover. Dev Cell (2017) 0.75
The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex. J Biol Chem (2016) 0.75
The guanine nucleotide exchange factor Rlf interacts with SH3 domain-containing proteins via a binding site with a preselected conformation. J Struct Biol (2013) 0.75
Photodynamic therapy as novel nephron sparing treatment option for small renal masses. J Urol (2011) 0.75