Published in J Pathol on October 28, 2011
Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer. Br J Cancer (2012) 1.15
Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing. Expert Rev Mol Diagn (2012) 0.97
Large-scale RNA-Seq Transcriptome Analysis of 4043 Cancers and 548 Normal Tissue Controls across 12 TCGA Cancer Types. Sci Rep (2015) 0.95
The prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma. Oncotarget (2015) 0.92
Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells. Drug Des Devel Ther (2015) 0.92
ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for carcinogenesis and subsequent progression. Oncotarget (2015) 0.91
The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Mol Cell Biol (2013) 0.91
Neuronal cell cycle: the neuron itself and its circumstances. Cell Cycle (2015) 0.90
Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development. Cell Death Dis (2014) 0.88
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun (2015) 0.87
K(+) channels and cell cycle progression in tumor cells. Front Physiol (2013) 0.87
DEPDC1 is a novel cell cycle related gene that regulates mitotic progression. BMB Rep (2015) 0.86
The modulation of the cell-cycle: a sentinel to alert the NK cells of dangers. Front Immunol (2013) 0.86
p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress. Cell Cycle (2016) 0.85
BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy. Oncotarget (2015) 0.84
Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells. Drug Des Devel Ther (2015) 0.84
A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesis. PLoS One (2014) 0.84
Bitter melon reduces head and neck squamous cell carcinoma growth by targeting c-Met signaling. PLoS One (2013) 0.83
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint. J Proteome Res (2013) 0.83
Luteolin suppresses cancer cell proliferation by targeting vaccinia-related kinase 1. PLoS One (2014) 0.83
The roles of BTG3 expression in gastric cancer: a potential marker for carcinogenesis and a target molecule for gene therapy. Oncotarget (2015) 0.82
Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint. Oncotarget (2016) 0.82
p42.3: a promising biomarker for the progression and prognosis of human colorectal cancer. J Cancer Res Clin Oncol (2013) 0.81
Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes. World J Gastroenterol (2016) 0.81
PFTK1 Promotes Gastric Cancer Progression by Regulating Proliferation, Migration and Invasion. PLoS One (2015) 0.80
Evolution of network biomarkers from early to late stage bladder cancer samples. Biomed Res Int (2014) 0.80
Artonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer Cells. PLoS One (2016) 0.79
Cell cycle analysis can differentiate thin melanomas from dysplastic nevi and reveals accelerated replication in thick melanomas. Virchows Arch (2014) 0.79
Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication. Cell Cycle (2015) 0.79
Functional Module Analysis for Gene Coexpression Networks with Network Integration. IEEE/ACM Trans Comput Biol Bioinform (2015) 0.78
Transcriptome Profiling Reveals the Antitumor Mechanism of Polysaccharide from Marine Algae Gracilariopsis lemaneiformis. PLoS One (2016) 0.78
TSG101 Silencing Suppresses Hepatocellular Carcinoma Cell Growth by Inducing Cell Cycle Arrest and Autophagic Cell Death. Med Sci Monit (2015) 0.78
Dysregulation of the PI3K/Akt signaling pathway affects cell cycle and apoptosis of side population cells in nasopharyngeal carcinoma. Oncol Lett (2015) 0.78
Classic "broken cell" techniques and newer live cell methods for cell cycle assessment. Am J Physiol Cell Physiol (2013) 0.78
New castanospermine glycoside analogues inhibit breast cancer cell proliferation and induce apoptosis without affecting normal cells. PLoS One (2013) 0.78
Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+‑mediated mitochondrial pathway. Mol Med Rep (2016) 0.78
The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model. Oncol Rep (2012) 0.77
p14 expression differences in ovarian benign, borderline and malignant epithelial tumors. J Ovarian Res (2016) 0.76
Mechanisms of cancer cell killing by the adenovirus E4orf4 protein. Viruses (2015) 0.76
Discriminating cancer-related and cancer-unrelated chemoradiation-response genes for locally advanced rectal cancers. Sci Rep (2016) 0.75
Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii. Drug Des Devel Ther (2016) 0.75
Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer. J Exp Clin Cancer Res (2016) 0.75
BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers. Oncotarget (2017) 0.75
Anti-ABCG2 scFv antibody of lung adenocarcinoma increases chemosensitivity and induces apoptosis through the activation of mitochondrial pathway. Am J Cancer Res (2016) 0.75
Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2. Mol Med Rep (2016) 0.75
3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells. Int J Oncol (2017) 0.75
Doxycycline-Regulated p16(MTS1) Expression Suppresses the Anchorage-Independence and Tumorigenicity of Breast Cancer Cell Lines that Lack Endogenous p16. J Cancer (2017) 0.75
Optical coherence tomography accurately identifies patients with penile (pre) malignant lesions: A single center prospective study. Urol Ann (2015) 0.75
High phosphohistone H3 expression correlates with adverse clinical, biological, and pathological factors in neuroblastomas. J Histochem Cytochem (2015) 0.75
Applying NGS Data to Find Evolutionary Network Biomarkers from the Early and Late Stages of Hepatocellular Carcinoma. Biomed Res Int (2015) 0.75
The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study. Oncotarget (2017) 0.75
High proliferation index, as determined by immunohistochemical expression of Aurora kinase B and geminin, indicates poor prognosis in neuroblastomas. Virchows Arch (2015) 0.75
Antiproliferative and Pro-Apoptotic Effect of Novel Nitro-Substituted Hydroxynaphthanilides on Human Cancer Cell Lines. Int J Mol Sci (2016) 0.75
Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines. J Orthop Surg Res (2015) 0.75
The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer. Int J Oncol (2017) 0.75
Anti-cancer agents in Saudi Arabian herbals revealed by automated high-content imaging. PLoS One (2017) 0.75
Acacetin enhances the therapeutic efficacy of doxorubicin in non-small-cell lung carcinoma cells. PLoS One (2017) 0.75
Expression of cell cycle markers is predictive of the response to primary systemic therapy of locally advanced breast cancer. Virchows Arch (2016) 0.75
The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67. Oncotarget (2017) 0.75
Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells. Nat Methods (2007) 1.61
Mcm2, Geminin, and KI67 define proliferative state and are prognostic markers in renal cell carcinoma. Clin Cancer Res (2005) 1.50
DNA replication licensing in somatic and germ cells. J Cell Sci (2004) 1.21
Commitment point during G0-->G1 that controls entry into the cell cycle. Mol Cell Biol (2003) 1.21
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci U S A (2011) 1.18
Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblasts. J Biol Chem (2004) 1.14
Cell cycle markers in clinical oncology. Curr Opin Cell Biol (2007) 1.12
Hexameric ring structure of human MCM10 DNA replication factor. EMBO Rep (2007) 1.10
Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells. Exp Cell Res (2005) 1.07
Biomarkers in bladder cancer. Histopathology (2010) 1.04
Molecular architecture of the DNA replication origin activation checkpoint. EMBO J (2010) 1.04
Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers. Am J Pathol (2010) 0.99
Cdc7 kinase is a predictor of survival and a novel therapeutic target in epithelial ovarian carcinoma. Clin Cancer Res (2009) 0.98
DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma. Clin Cancer Res (2007) 0.95
Cdc6 is a rate-limiting factor for proliferative capacity during HL60 cell differentiation. Exp Cell Res (2007) 0.93
Molecular structure of human geminin. Nat Struct Mol Biol (2004) 0.91
DNA replication licensing in peripheral B-cell lymphoma. J Pathol (2005) 0.87
Expression of Ki67, PCNA and the chromosome replication licensing protein Mcm2 in glial cells of the ageing human hippocampus increases with the burden of Alzheimer-type pathology. Neurosci Lett (2005) 0.86
DNA replication licensing factors and aneuploidy are linked to tumor cell cycle state and clinical outcome in penile carcinoma. Clin Cancer Res (2009) 0.85
Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer. J Pathol (2014) 0.84
Cell proliferation and granule cell dispersion in human hippocampal sclerosis. J Neuropathol Exp Neurol (2005) 0.83
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint. J Proteome Res (2013) 0.83
Novel markers of cell kinetics to evaluate progression from cirrhosis to hepatocellular carcinoma. Liver Int (2006) 0.83
Identification of an arginine-rich motif in human papillomavirus type 1 E1;E4 protein necessary for E4-mediated inhibition of cellular DNA synthesis in vitro and in cells. J Virol (2008) 0.81
Exploring the interaction between siRNA and the SMoC biomolecule transporters: implications for small molecule-mediated delivery of siRNA. Chem Biol Drug Des (2011) 0.80
Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22. PLoS One (2012) 0.80
Quantitative proteomics reveals a "poised quiescence" cellular state after triggering the DNA replication origin activation checkpoint. J Proteome Res (2010) 0.78
Modular assembly using sequential palladium coupling gives easy access to the SMoC class of cellular transporters. Chembiochem (2008) 0.77
Nuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stress. J Proteome Res (2014) 0.76