Published in EMBO Rep on September 07, 2007
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Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation. Mol Biol Cell (2003) 1.60
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The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. Nucleic Acids Res (2000) 1.49
The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase. Proc Natl Acad Sci U S A (2003) 1.47
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Cell cycle-dependent proteolysis and phosphorylation of human Mcm10. J Biol Chem (2001) 1.40
Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. J Biol Chem (2004) 1.37
Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae. Genes Cells (2000) 1.36
A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast. J Biol Chem (2006) 1.27
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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem Biol (2010) 5.61
Structural basis of pore formation by the bacterial toxin pneumolysin. Cell (2005) 2.87
Structural framework for DNA translocation via the viral portal protein. EMBO J (2007) 2.58
Structure of the Escherichia coli ribosomal termination complex with release factor 2. Nature (2003) 2.54
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Membrane bending by protein-protein crowding. Nat Cell Biol (2012) 2.27
The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature (2010) 2.23
Structure of bacteriophage SPP1 tail reveals trigger for DNA ejection. EMBO J (2007) 1.81
Atomic structure and hierarchical assembly of a cross-β amyloid fibril. Proc Natl Acad Sci U S A (2013) 1.75
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Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells. Nat Methods (2007) 1.61
Structure of the acrosomal bundle. Nature (2004) 1.59
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Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating. Proc Natl Acad Sci U S A (2009) 1.56
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Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damage. Cancer Res (2010) 1.53
Topologies of a substrate protein bound to the chaperonin GroEL. Mol Cell (2007) 1.52
Mcm2, Geminin, and KI67 define proliferative state and are prognostic markers in renal cell carcinoma. Clin Cancer Res (2005) 1.50
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Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. J Struct Biol (2007) 1.45
Challenges at the frontiers of structural biology. Nat Struct Biol (2002) 1.39
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO J (2010) 1.36
Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents. Proc Natl Acad Sci U S A (2012) 1.35
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Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein. J Virol (2012) 1.31
The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity. EMBO J (2006) 1.26
Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem (2005) 1.24
Direct three-dimensional visualization of membrane disruption by amyloid fibrils. Proc Natl Acad Sci U S A (2012) 1.24
Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils. J Mol Biol (2009) 1.21
DNA replication licensing in somatic and germ cells. J Cell Sci (2004) 1.21
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Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication. Proc Natl Acad Sci U S A (2012) 1.20
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci U S A (2011) 1.18
Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblasts. J Biol Chem (2004) 1.14
Removal of divalent cations induces structural transitions in red clover necrotic mosaic virus, revealing a potential mechanism for RNA release. J Virol (2006) 1.14
Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system. Proc Natl Acad Sci U S A (2012) 1.12
Cell cycle markers in clinical oncology. Curr Opin Cell Biol (2007) 1.12
Elongated oligomers assemble into mammalian PrP amyloid fibrils. J Mol Biol (2006) 1.10
Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells. Exp Cell Res (2005) 1.07
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26. Structure (2006) 1.06
Structure of a bacterial type IV secretion core complex at subnanometre resolution. EMBO J (2013) 1.05
Biomarkers in bladder cancer. Histopathology (2010) 1.04
Molecular architecture of the DNA replication origin activation checkpoint. EMBO J (2010) 1.04
Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. J Biol Chem (2010) 1.04
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases. Nucleic Acids Res (2007) 1.02
Mutant alpha-latrotoxin (LTXN4C) does not form pores and causes secretion by receptor stimulation: this action does not require neurexins. J Biol Chem (2003) 1.02
4.6A Cryo-EM reconstruction of tobacco mosaic virus from images recorded at 300 keV on a 4k x 4k CCD camera. J Struct Biol (2010) 1.00
Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers. Am J Pathol (2010) 0.99
Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy. Biochemistry (2003) 0.98
Cdc7 kinase is a predictor of survival and a novel therapeutic target in epithelial ovarian carcinoma. Clin Cancer Res (2009) 0.98
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Structural biology of the p53 tumour suppressor. Curr Opin Struct Biol (2009) 0.96
DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma. Clin Cancer Res (2007) 0.95
Structure of the hDmc1-ssDNA filament reveals the principles of its architecture. PLoS One (2010) 0.95
Capsid structure and its stability at the late stages of bacteriophage SPP1 assembly. J Virol (2012) 0.94
Cdc6 is a rate-limiting factor for proliferative capacity during HL60 cell differentiation. Exp Cell Res (2007) 0.93
An expanded and flexible form of the vacuolar ATPase membrane sector. Structure (2006) 0.92
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Structural analysis of the Saf pilus by electron microscopy and image processing. J Mol Biol (2008) 0.90
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Quaternary structure of the specific p53-DNA complex reveals the mechanism of p53 mutant dominance. Nucleic Acids Res (2011) 0.89
Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens. Structure (2006) 0.87
DNA replication licensing in peripheral B-cell lymphoma. J Pathol (2005) 0.87
Expression of Ki67, PCNA and the chromosome replication licensing protein Mcm2 in glial cells of the ageing human hippocampus increases with the burden of Alzheimer-type pathology. Neurosci Lett (2005) 0.86
The CDK subunit CKS2 counteracts CKS1 to control cyclin A/CDK2 activity in maintaining replicative fidelity and neurodevelopment. Dev Cell (2012) 0.85
CC chemokine ligand 7 expression in liver metastasis of colorectal cancer. Oncol Rep (2012) 0.85
DNA replication licensing factors and aneuploidy are linked to tumor cell cycle state and clinical outcome in penile carcinoma. Clin Cancer Res (2009) 0.85
Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer. J Pathol (2014) 0.84
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint. J Proteome Res (2013) 0.83
Cell proliferation and granule cell dispersion in human hippocampal sclerosis. J Neuropathol Exp Neurol (2005) 0.83
Novel markers of cell kinetics to evaluate progression from cirrhosis to hepatocellular carcinoma. Liver Int (2006) 0.83
Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation. Nucleic Acids Res (2013) 0.82