PubRank

D Mochly-Rosen

Author PubWeight™ 87.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins. Proc Natl Acad Sci U S A 1994 3.95
2 Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC. Proc Natl Acad Sci U S A 2001 3.28
3 Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol 2000 3.13
4 Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation. Proc Natl Acad Sci U S A 1999 2.44
5 Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C. J Neurosci 2000 2.20
6 A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function. J Biol Chem 1996 2.16
7 A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death. J Biol Chem 1997 2.03
8 Adaptor proteins in protein kinase C-mediated signal transduction. Oncogene 2001 1.99
9 C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo. J Biol Chem 1995 1.82
10 Localization of protein kinase C isozymes in cardiac myocytes. Exp Cell Res 1994 1.82
11 The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon. J Biol Chem 1997 1.76
12 Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J Biol Chem 1998 1.74
13 An autoregulatory region in protein kinase C: the pseudoanchoring site. Proc Natl Acad Sci U S A 1995 1.67
14 Domain structure and phosphorylation of protein kinase C. J Biol Chem 1987 1.65
15 Peptide modulators of protein-protein interactions in intracellular signaling. Nat Biotechnol 1998 1.62
16 Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). Chem Biol 2001 1.58
17 Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C. J Biol Chem 2001 1.50
18 An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia. J Biol Chem 1999 1.42
19 Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc Natl Acad Sci U S A 1986 1.40
20 Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells. J Biol Chem 1997 1.40
21 Protein kinase C-epsilon is responsible for the protection of preconditioning in rabbit cardiomyocytes. J Mol Cell Cardiol 1999 1.33
22 RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro. Biochemistry 1999 1.27
23 Mitochondrial protein kinase Cepsilon (PKCepsilon): emerging role in cardiac protection from ischaemic damage. Biochem Soc Trans 2007 1.24
24 Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: role of epsilon protein kinase C. Proc Natl Acad Sci U S A 1999 1.23
25 Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells. J Cell Biol 1994 1.23
26 An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research. Circ Res 1996 1.17
27 The roles of PKCdelta and epsilon isoenzymes in the regulation of myocardial ischaemia/reperfusion injury. Biochem Soc Trans 2007 1.17
28 Agonists and antagonists of protein kinase C function, derived from its binding proteins. J Biol Chem 1994 1.14
29 Opposing effects of delta and xi PKC in ethanol-induced cardioprotection. J Mol Cell Cardiol 2001 1.13
30 The HIV nef protein associates with protein kinase C theta. J Biol Chem 1996 1.12
31 The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor. Proc Natl Acad Sci U S A 1995 1.10
32 Inhibition of the spontaneous rate of contraction of neonatal cardiac myocytes by protein kinase C isozymes. A putative role for the epsilon isozyme. Circ Res 1995 1.09
33 Pharmacologic modulation of protein kinase C isozymes: the role of RACKs and subcellular localisation. Pharmacol Res 1999 1.06
34 Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C. Biochemistry 1987 1.06
35 Evidence for functional role of epsilonPKC isozyme in the regulation of cardiac Ca(2+) channels. Am J Physiol Heart Circ Physiol 2000 1.04
36 Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis. J Cell Biol 1996 1.04
37 Monoclonal anti-acetylcholine-receptor antibodies directed against the cholinergic binding site. Biochemistry 1981 1.03
38 C2 region-derived peptides of beta-protein kinase C regulate cardiac Ca2+ channels. Circ Res 1997 1.03
39 Localization, anchoring, and functions of protein kinase C isozymes in the heart. J Mol Cell Cardiol 2001 1.02
40 Inhibition of protein kinase C function by injection of intracellular receptors for the enzyme. Biochem Biophys Res Commun 1992 1.01
41 An inhibitory fragment derived from protein kinase Cepsilon prevents enhancement of nerve growth factor responses by ethanol and phorbol esters. J Biol Chem 1997 1.01
42 Sustained inhibition of PKCα reduces intravasation and lung seeding during mammary tumor metastasis in an in vivo mouse model. Oncogene 2010 1.00
43 Distinct cellular and regional localization of immunoreactive protein kinase C in rat brain. Proc Natl Acad Sci U S A 1987 0.99
44 Activation of epsilon protein kinase C correlates with a cardioprotective effect of regular ethanol consumption. Proc Natl Acad Sci U S A 1998 0.97
45 Interaction of monoclonal antibodies to Torpedo acetylcholine receptor with the receptor of skeletal muscle. Muscle Nerve 1983 0.93
46 Distinct responses of protein kinase C isozymes to c-erbB-2 activation in SKBR-3 human breast carcinoma cells. Cell Growth Differ 1994 0.93
47 Evidence for functional role of epsilonPKC isozyme in the regulation of cardiac Na(+) channels. Am J Physiol Cell Physiol 2001 0.92
48 Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis. J Biol Chem 1999 0.91
49 Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: a personal account and progress report on transferring academic discoveries to the clinic. Biochem Soc Trans 2007 0.90
50 Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C. Cardiovasc Res 2001 0.90
51 Monoclonal antibodies modify acetylcholine-induced ionic channel properties in cultured chick myoballs. J Membr Biol 1983 0.89
52 Exposure of HeLa DNA polymerase alpha to protein kinase C affects its catalytic properties. J Biol Chem 1987 0.89
53 The identification and purification of a mammalian-like protein kinase C in the yeast Saccharomyces cerevisiae. Proc Biol Sci 1991 0.88
54 Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C. Proc Natl Acad Sci U S A 1994 0.87
55 Proteins kinase Cɛ is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes. Oncogene 2011 0.87
56 The role of adenosine and adenosine transport in ethanol-induced cellular tolerance and dependence. Possible biologic and genetic markers of alcoholism. Ann N Y Acad Sci 1991 0.86
57 Characterization of the binding and phosphorylation of cardiac calsequestrin by epsilon protein kinase C. FEBS Lett 1999 0.86
58 DeltaPKC-mediated activation of epsilonPKC in ethanol-induced cardiac protection from ischemia. J Mol Cell Cardiol 2005 0.83
59 Chronic ethanol-induced heterologous desensitization is mediated by changes in adenosine transport. Biochem Soc Symp 1990 0.83
60 Islet cell survival during isolation improved through protein kinase C epsilon activation. Transplant Proc 2008 0.82
61 Stimulus-dependent subcellular localization of activated protein kinase C; a study with acidic fibroblast growth factor and transforming growth factor-beta 1 in cardiac myocytes. J Mol Cell Cardiol 1995 0.82
62 An anti-acetylcholine receptor monoclonal antibody cross-reacts with phosvitin. FEBS Lett 1983 0.82
63 Antigenic specificity of acetylcholine receptor in developing muscle. Studies with monoclonal antibodies. J Neuroimmunol 1985 0.81
64 Nicotinic acetylcholine receptor desensitization is regulated by activation-induced extracellular adenosine accumulation. J Neurosci 1992 0.80
65 Differential activation of protein kinase C isozymes by phorbol ester and collagen in human skin microvascular endothelial cells. J Invest Dermatol 1996 0.79
66 Acetylcholine receptor: molecular dissection and monoclonal antibodies in the study of experimental myasthenia. Ann N Y Acad Sci 1981 0.79
67 Involvement of a p38 mitogen-activated protein kinase phosphatase in protecting neonatal rat cardiac myocytes from ischemia. J Mol Cell Cardiol 2000 0.79
68 Developmental expression of protein kinase C subspecies in rat brain-pituitary axis. Mol Cell Endocrinol 1994 0.77
69 Immune regulation of experimental myasthenia. J Neurol Neurosurg Psychiatry 1980 0.75
70 Molecular aspects of experimental autoimmune myasthenia gravis. Prog Clin Biol Res 1981 0.75
71 Modification of acetylcholine receptor: chemical and immunological characterization of polyalanyl acetylcholine receptor. FEBS Lett 1980 0.75
72 Molecular genetic approaches. II. Expression-interaction cloning. Methods Mol Biol 1998 0.75
73 Prolonged phorbol ester treatment down-regulates protein kinase C isozymes and increases contraction rate in neonatal cardiac myocytes. Life Sci 1995 0.75