Published in Hum Mol Genet on October 18, 2011
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Dendritic pathology in prion disease starts at the synaptic spine. J Neurosci (2007) 1.57
Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. J Biol Chem (2008) 1.56
Cytogenetic prognostication within medulloblastoma subgroups. J Clin Oncol (2014) 1.56
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Ligand-independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice. Exp Dermatol (2013) 1.54
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ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta. PLoS Genet (2008) 1.37
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. J Biol Chem (2014) 1.37
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Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. J Neurosci (2009) 1.35
Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality. Proc Natl Acad Sci U S A (2004) 1.35
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathol (2013) 1.35
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol (2013) 1.34
Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods? J Nucl Med (2006) 1.33
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation. PLoS One (2010) 1.33
Genetic Creutzfeldt-Jakob disease and fatal familial insomnia: insights into phenotypic variability and disease pathogenesis. Acta Neuropathol (2010) 1.32
Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification. Acta Neuropathol (2009) 1.32
Autocatalytic self-propagation of misfolded prion protein. Proc Natl Acad Sci U S A (2004) 1.30
Calcium dysregulation in Alzheimer's disease. Neurochem Int (2007) 1.30
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors. Int J Cancer (2012) 1.30
Phenotypic variability of sporadic human prion disease and its molecular basis: past, present, and future. Acta Neuropathol (2010) 1.29
Cellular prion protein function in copper homeostasis and redox signalling at the synapse. J Neurochem (2003) 1.28
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A FOXO-Pak1 transcriptional pathway controls neuronal polarity. Genes Dev (2010) 1.27
Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect. FASEB J (2002) 1.26
Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. PLoS Med (2008) 1.26
Generation and characterization of dickkopf3 mutant mice. Mol Cell Biol (2006) 1.26
Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. J Neurosci (2011) 1.26
Systemic first-line phenotyping. Methods Mol Biol (2009) 1.26
Escherichia coli infection induces distinct local and systemic transcriptome responses in the mammary gland. BMC Genomics (2010) 1.25
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathol (2006) 1.24
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. J Cell Sci (2011) 1.24
Epigenetic regulation of lentiviral transgene vectors in a large animal model. Mol Ther (2005) 1.23
Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients. Clin Cancer Res (2011) 1.23
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region. J Biol Chem (2004) 1.23
Generation of transgenic cattle by lentiviral gene transfer into oocytes. Biol Reprod (2004) 1.21
Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing. J Biol Chem (2003) 1.21
Peroxiredoxin 6 is a potent cytoprotective enzyme in the epidermis. Am J Pathol (2006) 1.20
Elevated expression of Wnt antagonists is a common event in hepatoblastomas. Clin Cancer Res (2005) 1.20
Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein. J Biol Chem (2002) 1.20
Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. Am J Pathol (2005) 1.20
Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice. J Clin Invest (2006) 1.19
Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. Mol Biol Cell (2004) 1.18
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. PLoS One (2010) 1.17
Mixed brain pathologies in dementia: the BrainNet Europe consortium experience. Dement Geriatr Cogn Disord (2008) 1.17
Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium. Acta Neuropathol (2009) 1.17
Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. Biochem J (2008) 1.16
Positron emission tomography with O-(2-[18F]fluoroethyl)-l-tyrosine versus magnetic resonance imaging in the diagnosis of recurrent gliomas. Neurosurgery (2005) 1.15
Invasion of tumorigenic HT1080 cells is impeded by blocking or downregulating the 37-kDa/67-kDa laminin receptor. J Mol Biol (2008) 1.14
A bovine oviduct epithelial cell suspension culture system suitable for studying embryo-maternal interactions: morphological and functional characterization. Reproduction (2006) 1.14
Completion of the swine genome will simplify the production of swine as a large animal biomedical model. BMC Med Genomics (2012) 1.14
Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium. Acta Neuropathol (2008) 1.13
Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion. Proc Natl Acad Sci U S A (2013) 1.13