Global chromatin fibre compaction in response to DNA damage.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 3459090)

Published in Biochem Biophys Res Commun on October 12, 2011

Authors

Charlotte Hamilton1, Richard L Hayward, Nick Gilbert

Author Affiliations

1: Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh EH4 2XR, UK.

Articles cited by this

Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol (1999) 16.81

The DNA damage response: ten years after. Mol Cell (2007) 11.80

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell (2008) 6.60

Chromatin architecture of the human genome: gene-rich domains are enriched in open chromatin fibers. Cell (2004) 5.84

Genome instability: a mechanistic view of its causes and consequences. Nat Rev Genet (2008) 5.41

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nat Cell Biol (2006) 5.34

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat Cell Biol (2010) 2.88

Heterochromatin protein 1 is recruited to various types of DNA damage. J Cell Biol (2009) 2.26

Electrostatic mechanism of chromatin folding. J Mol Biol (1990) 2.18

p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage. EMBO J (2003) 1.97

Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin. Mol Cell Biol (1999) 1.97

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nat Struct Mol Biol (2011) 1.77

KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions. Cancer Res (2006) 1.72

High resolution imaging of changes in the structure and spatial organization of chromatin, gamma-H2A.X and the MRN complex within etoposide-induced DNA repair foci. Cell Cycle (2009) 1.68

Distinctive higher-order chromatin structure at mammalian centromeres. Proc Natl Acad Sci U S A (2001) 1.47

HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J Cell Biol (2011) 1.47

Formation of facultative heterochromatin in the absence of HP1. EMBO J (2003) 1.45

DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction. J Cell Biol (2007) 1.39

Chromatin organization in the mammalian nucleus. Int Rev Cytol (2005) 1.29

Histone H1 and chromatin higher-order structure. Crit Rev Eukaryot Gene Expr (1997) 1.23

Phosphorylation and dephosphorylation of histone (V (H5): controlled condensation of avian erythrocyte chromatin. Appendix: Phosphorylation and dephosphorylation of histone H5. II. Circular dichroic studies. Biochemistry (1977) 1.10

Selective synthesis and modification of nuclear proteins during maturation of avian erythroid cells. Arch Biochem Biophys (1976) 1.06

Changes in nuclease sensitivity of mammalian cells after irradiation with 60Co gamma-rays. Int J Radiat Biol Relat Stud Phys Chem Med (1985) 0.96

Inhibition of proliferation of primary avian fibroblasts through expression of histone H5 depends on the degree of phosphorylation of the protein. J Cell Biol (1991) 0.87

Histone H1 dephosphorylation is mediated through a radiation-induced signal transduction pathway dependent on ATM. J Biol Chem (1999) 0.86

Articles by these authors

Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell (2010) 4.69

Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol Cell Biol (2004) 3.76

The role of chromatin structure in regulating the expression of clustered genes. Nat Rev Genet (2005) 3.40

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks. Oncogene (2004) 2.36

Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures. Nat Struct Mol Biol (2013) 2.09

The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci. Nat Cell Biol (2004) 1.90

Chromatin structure and evolution in the human genome. BMC Evol Biol (2007) 1.67

Increased incidence of visceral metastases in scottish patients with BRCA1/2-defective ovarian cancer: an extension of the ovarian BRCAness phenotype. J Clin Oncol (2010) 1.25

Analysis of active and inactive X chromosome architecture reveals the independent organization of 30 nm and large-scale chromatin structures. Mol Cell (2010) 1.14

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression. Nucleic Acids Res (2012) 1.12

Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases. Chromosome Res (2004) 1.11

DNA methylation in mouse embryonic stem cells and development. Cell Tissue Res (2007) 1.01

Altered protein dynamics of disease-associated lamin A mutants. BMC Cell Biol (2004) 0.92

p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program. Cell Cycle (2011) 0.89

Characterisation of osteoprotegerin autoantibodies in coeliac disease. Calcif Tissue Int (2015) 0.85

Divergent RNA transcription: a role in promoter unwinding? Transcription (2013) 0.81

Strategies for p53 reactivation in human sarcoma. Cancer Cell (2012) 0.78

Possible Radiation Sensitisation by Trastuzumab Leading to Radiation-Induced Myelitis. Breast Care (Basel) (2009) 0.78

Genomic profiling of type-1 adult diabetic and aged normoglycemic mouse liver. BMC Endocr Disord (2014) 0.78

Quantitative proteomic profiling of pleomorphic human sarcoma identifies CLIC1 as a dominant pro-oncogenic receptor expressed in diverse sarcoma types. J Proteome Res (2014) 0.77

Elective tracheotomy facilitates total artificial heart implantation in calves. ASAIO J (2009) 0.75

Investigating DNA supercoiling in eukaryotic genomes. Brief Funct Genomics (2017) 0.75

Polymers for the cell-specific immobilisation of megakaryocytic cell lines. Macromol Biosci (2013) 0.75