Published in Curr Opin Genet Dev on October 25, 2011
How cells know where they are. Science (2013) 1.20
Cytonemes as specialized signaling filopodia. Development (2014) 1.17
Dynamics of TGF-β/Smad signaling. FEBS Lett (2012) 1.12
An introduction to proteoglycans and their localization. J Histochem Cytochem (2012) 1.08
Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution. Philos Trans R Soc Lond B Biol Sci (2013) 1.06
Dynamics and precision in retinoic acid morphogen gradients. Curr Opin Genet Dev (2012) 1.00
Beyond generalized hair cells: molecular cues for hair cell types. Hear Res (2012) 0.94
Comparative study of non-invasive force and stress inference methods in tissue. Eur Phys J E Soft Matter (2013) 0.94
Modeling Wnt/β-Catenin Target Gene Expression in APC and Wnt Gradients Under Wild Type and Mutant Conditions. Front Physiol (2013) 0.83
Cytonemes and the dispersion of morphogens. Wiley Interdiscip Rev Dev Biol (2014) 0.83
An epidermis-driven mechanism positions and scales stem cell niches in plants. Sci Adv (2016) 0.80
Design principles of stripe-forming motifs: the role of positive feedback. Sci Rep (2014) 0.80
Only accessible information is useful: insights from gradient-mediated patterning. R Soc Open Sci (2015) 0.79
The organelle of differentiation in embryos: the cell state splitter. Theor Biol Med Model (2016) 0.76
Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling. Elife (2017) 0.75
An Extra Arm May Impair the Open Hand. Endocrinology (2015) 0.75
We also CanFly! The 2nd MexFly Drosophila Research Conference. Fly (Austin) (2016) 0.75
A Boolean Function for Neural Induction Reveals a Critical Role of Direct Intercellular Interactions in Patterning the Ectoderm of the Ascidian Embryo. PLoS Comput Biol (2015) 0.75
Spatial manipulation with microfluidics. Front Bioeng Biotechnol (2015) 0.75
John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work? Dev Biol (2017) 0.75
Positional information and the spatial pattern of cellular differentiation. J Theor Biol (1969) 9.25
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell (1988) 7.72
A gradient of bicoid protein in Drosophila embryos. Cell (1988) 7.30
The gradient morphogen bicoid is a concentration-dependent transcriptional activator. Cell (1989) 4.72
Direct and long-range action of a DPP morphogen gradient. Cell (1996) 4.33
Dual roles for patched in sequestering and transducing Hedgehog. Cell (1996) 4.10
Morphogen gradient interpretation. Nature (2001) 3.90
Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature (1996) 3.81
Morpheus unbound: reimagining the morphogen gradient. Cell (2007) 3.49
Dynamics of Dpp signaling and proliferation control. Science (2011) 3.48
The incoherent feedforward loop can provide fold-change detection in gene regulation. Mol Cell (2009) 3.38
The interpretation of morphogen gradients. Development (2006) 3.28
Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature (1990) 3.27
Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature (2007) 2.97
Morphogen control of wing growth through the Fat signaling pathway. Dev Cell (2008) 2.80
Activin signalling and response to a morphogen gradient. Nature (1994) 2.70
Dynamics and variability of ERK2 response to EGF in individual living cells. Mol Cell (2009) 2.42
Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development (1995) 2.38
Morphogen gradients: from generation to interpretation. Annu Rev Cell Dev Biol (2011) 2.19
Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling. Mol Cell (2009) 2.11
Regulation of cell proliferation by a morphogen gradient. Cell (2005) 1.81
Expansion-repression mechanism for scaling the Dpp activation gradient in Drosophila wing imaginal discs. Curr Biol (2011) 1.79
Retinoid signalling in the development of the central nervous system. Nat Rev Neurosci (2002) 1.77
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell (1998) 1.61
Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol (2010) 1.58
Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development (2008) 1.54
eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J (1994) 1.51
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev (2010) 1.51
Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb. Dev Biol (2007) 1.49
Signal dynamics in Sonic hedgehog tissue patterning. Development (2006) 1.43
Incredible journey: how do developmental signals travel through tissue? Genes Dev (2004) 1.38
Development and determination of hairs and bristles in the milkweed bug, Oncopeltus fasciatus (Lygaeidae, Hemiptera). J Cell Sci (1966) 1.24
Mesoderm formation in response to Brachyury requires FGF signalling. Curr Biol (1995) 1.23
Direct and continuous assessment by cells of their position in a morphogen gradient. Nature (1995) 1.22
Scaling of morphogen gradients by an expansion-repression integral feedback control. Proc Natl Acad Sci U S A (2010) 1.19
Dynamic interpretation of hedgehog signaling in the Drosophila wing disc. PLoS Biol (2009) 1.18
Interaction of goosecoid and brachyury in Xenopus mesoderm patterning. Mech Dev (1997) 1.14
Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction. Genes Dev (2005) 1.13
Cells' perception of position in a concentration gradient. Cell (1998) 1.07
A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development (2010) 1.07
Time of exposure to BMP signals plays a key role in the specification of the olfactory and lens placodes ex vivo. Dev Cell (2007) 1.01
ArRAnging the hindbrain. Trends Neurosci (2002) 0.95
Mechanism by which cells estimate their location within the body. Nature (1966) 0.91
Forming and interpreting gradients in the early Xenopus embryo. Cold Spring Harb Perspect Biol (2009) 0.86
Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B. Nat Genet (2004) 5.19
Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome. PLoS Genet (2009) 2.14
GDF11 controls the timing of progenitor cell competence in developing retina. Science (2005) 2.04
Formation of the BMP activity gradient in the Drosophila embryo. Dev Cell (2005) 1.98
Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome. PLoS Biol (2011) 1.77
Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol (2007) 1.68
Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells. J Cell Biol (2005) 1.51
Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. J Clin Invest (2008) 1.43
Widespread defects in the primary olfactory pathway caused by loss of Mash1 function. J Neurosci (2003) 1.36
Feedback regulation in multistage cell lineages. Math Biosci Eng (2009) 1.33
Cohesin mediates chromatin interactions that regulate mammalian β-globin expression. J Biol Chem (2011) 1.29
Cell lineage branching as a strategy for proliferative control. BMC Biol (2015) 1.22
Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc. Curr Biol (2012) 1.22
Heparan sulfate acts as a bone morphogenetic protein coreceptor by facilitating ligand-induced receptor hetero-oligomerization. Mol Biol Cell (2010) 1.18
Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development (2011) 1.09
Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development (2009) 1.08
Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue. Development (2009) 1.06
Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis. Neural Dev (2009) 1.03
Dynamics and precision in retinoic acid morphogen gradients. Curr Opin Genet Dev (2012) 1.00
Spatial dynamics of multistage cell lineages in tissue stratification. Biophys J (2010) 0.92
Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in zebrafish. Development (2012) 0.92
A reaction-diffusion mechanism influences cell lineage progression as a basis for formation, regeneration, and stability of intestinal crypts. BMC Syst Biol (2012) 0.91
ROBUSTNESS OF SIGNALING GRADIENT IN DROSOPHILA WING IMAGINAL DISC. Discrete Continuous Dyn Syst Ser B (2011) 0.90
Computational analysis of BMP gradients in dorsal-ventral patterning of the zebrafish embryo. J Theor Biol (2007) 0.86
Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome. Biochim Biophys Acta (2013) 0.83
Using mouse and zebrafish models to understand the etiology of developmental defects in Cornelia de Lange Syndrome. Am J Med Genet C Semin Med Genet (2016) 0.81
Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms. J R Soc Interface (2015) 0.81
Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster. BMC Syst Biol (2012) 0.80
Making sense in biology: an appreciation of Julian Lewis. BMC Biol (2014) 0.77
Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome. Am J Med Genet C Semin Med Genet (2016) 0.77
Discovery of a novel molecule that regulates tumor growth and metastasis. ScientificWorldJournal (2008) 0.75