Published in Biochim Biophys Acta on September 10, 1990
Charge balance in the alpha-hydroxyacid dehydrogenase vacuole: an acid test. Protein Sci (1992) 0.90
The amino acid sequence of leghaemoglobin I from root nodules of broad bean (Vicia faba L.). FEBS Lett (1975) 9.08
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature (1992) 7.66
T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell (1993) 4.18
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol (1995) 3.60
Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. Cell (1989) 3.20
Ethidium bromide as a cooperative effector of a DNA structure. Proc Natl Acad Sci U S A (1972) 3.06
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. Genes Dev (1999) 2.91
Characterization of a short, cis-acting DNA sequence which conveys cell cycle stage-dependent transcription in Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.91
Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases. Biochem J (1973) 2.77
Prion protein is necessary for normal synaptic function. Nature (1994) 2.69
Cystic fibrosis in the mouse by targeted insertional mutagenesis. Nature (1992) 2.66
A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework. Science (1988) 2.63
Strain-specific prion-protein conformation determined by metal ions. Nat Cell Biol (1999) 2.61
High-frequency developmental abnormalities in p53-deficient mice. Curr Biol (1995) 2.57
Ionic properties of an essential histidine residue in pig heart lactate dehydrogenase. Biochem J (1973) 2.35
EcoRV restriction endonuclease binds all DNA sequences with equal affinity. Biochemistry (1991) 2.23
Protein fluorescence of lactate dehydrogenase. Biochem J (1972) 2.21
PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology. Neurodegeneration (1994) 2.21
Location of a folding protein and shape changes in GroEL-GroES complexes imaged by cryo-electron microscopy. Nature (1994) 2.19
A specific endonuclease from Bacillus caldolyticus. Nucleic Acids Res (1978) 2.18
Location and properties of metal-binding sites on the human prion protein. Proc Natl Acad Sci U S A (2001) 2.16
Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesis. Cell (1984) 2.12
Cadmium-Resistant Pseudomonas putida Synthesizes Novel Cadmium Proteins. Science (1984) 2.07
Rapid cell-surface prion protein conversion revealed using a novel cell system. Nat Commun (2011) 2.04
Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos Trans R Soc Lond B Biol Sci (1991) 2.02
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations. Science (1999) 1.95
The meiotic checkpoint monitoring synapsis eliminates spermatocytes via p53-independent apoptosis. Nat Genet (1998) 1.87
Protein structure and gene organization of mouse lactate dehydrogenase-A isozyme. Eur J Biochem (1985) 1.85
Resisting and promoting new technologies in clinical practice: the case of telepsychiatry. Soc Sci Med (2001) 1.84
A single amino acid substitution in lactate dehydrogenase improves the catalytic efficiency with an alternative coenzyme. Biochem Biophys Res Commun (1990) 1.84
A modular esterase from Pseudomonas fluorescens subsp. cellulosa contains a non-catalytic cellulose-binding domain. Biochem J (1993) 1.80
Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding. Biochemistry (1993) 1.78
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene. Eur J Biochem (1990) 1.78
Nucleotide sequence of the putative regulatory region of mouse lactate dehydrogenase-A gene. Biochem J (1986) 1.76
Cloning, expression and complete nucleotide sequence of the Bacillus stearothermophilus L-lactate dehydrogenase gene. Gene (1986) 1.76
The use of ternary complexes to study ionizations and isomerizations during catalysis by lactate dehydrogenase. Biochem J (1973) 1.72
Molecular evolution of bacterial cell-surface proteins. Trends Biochem Sci (1993) 1.72
The identification of intermediates in the reaction of pig heart lactate dehydrogenase with its substrates. Biochem J (1974) 1.71
Amino acid sequence of small and large subunits of seed storage protein from Ricinus communis. J Biol Chem (1982) 1.70
The non-catalytic cellulose-binding domain of a novel cellulase from Pseudomonas fluorescens subsp. cellulosa is important for the efficient hydrolysis of Avicel. Biochem J (1995) 1.66
Source of catalysis in the lactate dehydrogenase system. Ground-state interactions in the enzyme-substrate complex. Biochemistry (1994) 1.64
Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase. J Biol Chem (2001) 1.61
The complete nucleotide sequence of the Pseudomonas gene coding for carboxypeptidase G2. Gene (1984) 1.57
Ketamine as an induction agent in anaesthetics. Lancet (1970) 1.55
Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution. J Mol Biol (1992) 1.54
Molecular cloning of the Pseudomonas carboxypeptidase G2 gene and its expression in Escherichia coli and Pseudomonas putida. J Bacteriol (1983) 1.54
Evolutionary relationships of vertebrate lactate dehydrogenase isozymes A4 (muscle), B4 (heart), and C4 (testis). J Biol Chem (1983) 1.53
An integrated kinetic analysis of intermediates and transition states in protein folding reactions. J Mol Biol (1995) 1.49
Reactivity of the essential thiol group of lactate dehydrogenase and substrate binding. Biochem J (1970) 1.48
High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. J Mol Biol (1999) 1.48
Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence. Appl Environ Microbiol (1992) 1.47
The location of the ligand-binding site of carbohydrate-binding modules that have evolved from a common sequence is not conserved. J Biol Chem (2001) 1.45
Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis. Nature (1987) 1.43
The origins and consequences of asymmetry in the chaperonin reaction cycle. J Mol Biol (1995) 1.42
The purification of restriction endonuclease EcoRI by precipitation involving polyethyleneimine. FEBS Lett (1977) 1.42
A peptide containing a reactive lysyl group from ox liver glutamate dehydrogenase. Biochem J (1969) 1.41
Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production. Metab Eng (2009) 1.41
Structural mobility of the human prion protein probed by backbone hydrogen exchange. Nat Struct Biol (1999) 1.41
Reye's syndrome: assessment of intracranial monitoring. Br Med J (Clin Res Ed) (1987) 1.41
Arabinanase A from Pseudomonas fluorescens subsp. cellulosa exhibits both an endo- and an exo- mode of action. Biochem J (1997) 1.40
Protein fluorescence of nicotinamide nucleotide-dependent dehydrogenases. Biochem J (1972) 1.40
The adenovirus and the egg: a new approach to transgenesis. Nat Biotechnol (1996) 1.39
Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting. Proc Natl Acad Sci U S A (1991) 1.39
Binding of a chaperonin to the folding intermediates of lactate dehydrogenase. Biochemistry (1991) 1.38
High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice. Cell Death Differ (1998) 1.38
Chaperonins can catalyse the reversal of early aggregation steps when a protein misfolds. J Mol Biol (1995) 1.36
The role of Stat3 in apoptosis and mammary gland involution. Conditional deletion of Stat3. Adv Exp Med Biol (2000) 1.34
Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine. Proc Natl Acad Sci U S A (1999) 1.33
The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway. J Biol Chem (2000) 1.33
Chromatographic isolation of the hemagglutinin polypeptides from influenza virus vaccine and determination of their amino-terminal sequences. Proc Natl Acad Sci U S A (1976) 1.33
Efficient BLG-Cre mediated gene deletion in the mammary gland. Transgenic Res (1998) 1.33
Mating compatibility among four pest members of the Bactrocera dorsalis fruit fly species complex (Diptera: Tephritidae). J Econ Entomol (2013) 1.32
Higher plant plastocyanin. Biochim Biophys Acta (1973) 1.32
Nucleotide sequence of the Erwinia chrysanthemi NCPPB 1066 L-asparaginase gene. Gene (1986) 1.31
The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene. Eur J Biochem (1992) 1.30
Multiple folding pathways for heterologously expressed human prion protein. Biochim Biophys Acta (1999) 1.29
Crystal structure of human prion protein bound to a therapeutic antibody. Proc Natl Acad Sci U S A (2009) 1.29
Molecular analysis of an IS200 insertion in the gpt gene of Salmonella typhimurium LT2. J Bacteriol (1990) 1.28
The conserved noncatalytic 40-residue sequence in cellulases and hemicellulases from anaerobic fungi functions as a protein docking domain. J Biol Chem (1995) 1.28
Novel cellulose-binding domains, NodB homologues and conserved modular architecture in xylanases from the aerobic soil bacteria Pseudomonas fluorescens subsp. cellulosa and Cellvibrio mixtus. Biochem J (1995) 1.27
CpG methylation directly inhibits binding of the human papillomavirus type 16 E2 protein to specific DNA sequences. J Virol (1996) 1.26