Published in Proc Natl Acad Sci U S A on November 23, 2011
Peptides as targeting elements and tissue penetration devices for nanoparticles. Adv Mater (2012) 1.41
Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells. J Med Chem (2012) 1.00
Targeted delivery of paclitaxel to EphA2-expressing cancer cells. Clin Cancer Res (2012) 0.96
Peptides as targeting probes against tumor vasculature for diagnosis and drug delivery. J Transl Med (2012) 0.96
Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling. Br J Pharmacol (2014) 0.85
Enhanced antitumor effects of the BRBP1 compound peptide BRBP1-TAT-KLA on human brain metastatic breast cancer. Sci Rep (2015) 0.80
Retro-inverso carbohydrate mimetic peptides with annexin1-binding selectivity, are stable in vivo, and target tumor vasculature. PLoS One (2013) 0.77
Tumor-targeted liposomal drug delivery mediated by a diseleno bond-stabilized cyclic peptide. Int J Nanomedicine (2013) 0.76
Specific protein markers for stem cell cross-talk with neighboring cells in the environment. Int J Stem Cells (2013) 0.75
Annexins: from structure to function. Physiol Rev (2002) 6.78
Annexins: linking Ca2+ signalling to membrane dynamics. Nat Rev Mol Cell Biol (2005) 5.71
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Mol Cell (2002) 3.89
Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci U S A (2002) 3.73
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts. Clin Cancer Res (2002) 3.72
Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 3.54
Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature (2004) 3.24
Annexins--unique membrane binding proteins with diverse functions. J Cell Sci (2004) 2.74
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res (1991) 2.70
Dorsal skinfold chamber technique for intravital microscopy in nude mice. Am J Pathol (1993) 2.60
Tumour vascular targeting. Nat Rev Cancer (2005) 2.56
Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases. J Biol Chem (1995) 2.41
Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res (1993) 2.39
Antimyeloma activity of heat shock protein-90 inhibition. Blood (2005) 2.24
Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J (2002) 2.13
Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol. Cancer Res (2003) 2.04
Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. Nat Med (1996) 1.96
Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin. Cancer Res (2002) 1.55
Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts. Cancer Chemother Pharmacol (2004) 1.55
Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines. J Natl Cancer Inst (2000) 1.46
Dual roles of sialyl Lewis X oligosaccharides in tumor metastasis and rejection by natural killer cells. EMBO J (1999) 1.42
A family of concanavalin A-binding peptides from a hexapeptide epitope library. Proc Natl Acad Sci U S A (1992) 1.42
An address system in the vasculature of normal tissues and tumors. Annu Rev Immunol (2000) 1.41
Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone. Oncogene (2000) 1.34
Annexin 1 and the biology of the neutrophil. J Leukoc Biol (2004) 1.32
Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts. Clin Cancer Res (2001) 1.26
Phase II clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme. J Neurosurg (2008) 1.16
A peptide mimic of E-selectin ligand inhibits sialyl Lewis X-dependent lung colonization of tumor cells. Cancer Res (2000) 1.10
Peptide-based drug design: here and now. Methods Mol Biol (2008) 1.06
Vaccination with carbohydrate peptide mimotopes promotes anti-tumor responses. Nat Biotechnol (1999) 1.02
DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies. Clin Cancer Res (2008) 0.97
Is phage display technology on target for developing peptide-based cancer drugs? Curr Drug Discov Technol (2004) 0.95
Determinants of CPT-11 and SN-38 activities in human lung cancer cells. Br J Cancer (1998) 0.91
Geldanamycin and its 17-allylamino-17-demethoxy analogue antagonize the action of Cisplatin in human colon adenocarcinoma cells: differential caspase activation as a basis for interaction. Cancer Res (2003) 0.90
Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists. Blood (2002) 0.86
Role of SA-Le(a) and E-selectin in metastasis assessed with peptide antagonist. Peptides (2002) 0.86
Identification of mRNA splicing factors as the endothelial receptor for carbohydrate-dependent lung colonization of cancer cells. Proc Natl Acad Sci U S A (2009) 0.86
A new approach for drug discovery from glycobiology and phage-displayed peptide library technology. Biochim Biophys Acta (2008) 0.82
Screening of peptide-displaying phage libraries to identify short peptides mimicking carbohydrates. Methods Enzymol (2006) 0.79
Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis. Nat Med (2008) 3.87
Structural basis for vinculin activation at sites of cell adhesion. Nature (2004) 3.62
Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation (2011) 2.94
Recreation of the terminal events in physiological integrin activation. J Cell Biol (2010) 2.48
Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment. Nat Immunol (2007) 2.41
Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation. J Biol Chem (2003) 2.24
Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes. Immunity (2010) 2.00
Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection. Science (2004) 1.99
N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules. Nat Immunol (2005) 1.91
Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science (2002) 1.87
A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Cell (2004) 1.73
Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice. Circulation (2008) 1.71
Core 2 N-acetylglucosaminyltransferase-1 expression induces aggressive potential of testicular germ cell tumor. Int J Cancer (2010) 1.58
An RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus. Antimicrob Agents Chemother (2010) 1.57
Small GTPase R-Ras regulates integrity and functionality of tumor blood vessels. Cancer Cell (2012) 1.56
Inflammatory pseudotumor of the lung: clinicopathological analysis in seven adult patients. Int J Clin Oncol (2006) 1.55
Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin. Cancer Res (2002) 1.55
Diacylglycerol kinase zeta inhibits G(alpha)q-induced atrial remodeling in transgenic mice. Heart Rhythm (2008) 1.54
Sensitivity to activated protein C in patients with deep vein thrombosis during early puerperium period. Acta Obstet Gynecol Scand (2005) 1.48
C1 esterase inhibitor activity in amniotic fluid embolism. Crit Care Med (2014) 1.48
Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-δ. Cell Cycle (2011) 1.48
Enhancement of human sperm motility by trophinin binding peptide. J Urol (2008) 1.48
Life-threatening veno-occlusive disease after living-related liver transplantation. Transplantation (2003) 1.46
Induction of peripheral lymph node addressin in human gastric mucosa infected by Helicobacter pylori. Proc Natl Acad Sci U S A (2004) 1.39
Differential expression of ribosomal proteins in human normal and neoplastic colorectum. J Histochem Cytochem (2003) 1.36
Structural determinants of integrin binding to the talin rod. J Biol Chem (2009) 1.35
Galectin-1 binds different CD43 glycoforms to cluster CD43 and regulate T cell death. J Immunol (2006) 1.34
Carbohydrate structure and differential binding of prostate specific antigen to Maackia amurensis lectin between prostate cancer and benign prostate hypertrophy. Glycobiology (2004) 1.33
Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. Proc Natl Acad Sci U S A (2009) 1.32
Oligosaccharide profiles of the prostate specific antigen in free and complexed forms from the prostate cancer patient serum and in seminal plasma: a glycopeptide approach. Glycobiology (2007) 1.31
Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase. Proc Natl Acad Sci U S A (2009) 1.30
Cofilin induced conformational changes in F-actin expose subdomain 2 to proteolysis. J Mol Biol (2004) 1.30
Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol (2009) 1.30
Clinical reevaluation of the QuantiFERON TB-2G test as a diagnostic method for differentiating active tuberculosis from nontuberculous mycobacteriosis. Clin Infect Dis (2006) 1.26
Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences. Gen Thorac Cardiovasc Surg (2013) 1.25
Polysialyltransferases: major players in polysialic acid synthesis on the neural cell adhesion molecule. Biochimie (2003) 1.25
αE-catenin is an autoinhibited molecule that coactivates vinculin. Proc Natl Acad Sci U S A (2012) 1.25
Possible involvement of gelatinases in basement membrane damage and wrinkle formation in chronically ultraviolet B-exposed hairless mouse. J Invest Dermatol (2003) 1.23
Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients. Transplantation (2004) 1.22
Outer membrane vesicles of Helicobacter pylori TK1402 are involved in biofilm formation. BMC Microbiol (2009) 1.22
Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow. J Exp Med (2006) 1.21
Suppression of tumor formation in lymph nodes by L-selectin-mediated natural killer cell recruitment. J Exp Med (2005) 1.21
A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans. EMBO J (2011) 1.18
Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing. J Biol Chem (2003) 1.16
Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior. J Biol Chem (2004) 1.16
Polysialic acid-directed migration and differentiation of neural precursors are essential for mouse brain development. Mol Cell Biol (2007) 1.15
hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins. Nat Commun (2013) 1.14
Extended core 1 and core 2 branched O-glycans differentially modulate sialyl Lewis X-type L-selectin ligand activity. J Biol Chem (2003) 1.14
Polysialic acid facilitates tumor invasion by glioma cells. Glycobiology (2005) 1.13
Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer. Cancer Res (2006) 1.12
A novel phosphatase upregulated in Akp3 knockout mice. Am J Physiol Gastrointest Liver Physiol (2007) 1.09
A mechanism of Rap1-induced stabilization of endothelial cell--cell junctions. Mol Biol Cell (2011) 1.09
Alpha1,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol alpha-glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth. Glycobiology (2008) 1.09
Mouse model of N-acetylgalactosamine-6-sulfate sulfatase deficiency (Galns-/-) produced by targeted disruption of the gene defective in Morquio A disease. Hum Mol Genet (2003) 1.08
Expression of core 2 beta1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression. Glycobiology (2005) 1.08
Symmetric dumbbell ganglioneuromas of bilateral C2 and C3 roots with intradural extension associated with von Recklinghausen's disease: case report. Surg Neurol (2004) 1.07
Expression cloning of cholesterol alpha-glucosyltransferase, a unique enzyme that can be inhibited by natural antibiotic gastric mucin O-glycans, from Helicobacter pylori. Biochem Biophys Res Commun (2006) 1.06
Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex. J Biol Chem (2009) 1.06
Structure of the alpha-actinin-vinculin head domain complex determined by cryo-electron microscopy. J Mol Biol (2006) 1.05
Altered T cell surface glycosylation in HIV-1 infection results in increased susceptibility to galectin-1-induced cell death. Glycobiology (2003) 1.05
Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5. Proc Natl Acad Sci U S A (2013) 1.04
Polymorphisms in prostate-specific antigen (PSA) gene, risk of prostate cancer, and serum PSA levels in Japanese population. Cancer Lett (2003) 1.04
Usefulness of the QuantiFERON TB-2G test for the differential diagnosis of pulmonary tuberculosis. Intern Med (2008) 1.04
Structural basis of membrane targeting by the Dock180 family of Rho family guanine exchange factors (Rho-GEFs). J Biol Chem (2010) 1.04
Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice. Proc Natl Acad Sci U S A (2006) 1.03
Community-acquired pneumonia in Japan: a prospective ambulatory and hospitalized patient study. J Med Microbiol (2005) 1.03
Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. J Clin Invest (2006) 1.03
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase. Proc Natl Acad Sci U S A (2006) 1.02
Efficacies and safety of neoadjuvant gemcitabine plus carboplatin followed by immediate cystectomy in patients with muscle-invasive bladder cancer, including those unfit for cisplatin: a prospective single-arm study. Int J Clin Oncol (2012) 1.02
Roles of gastric mucin-type O-glycans in the pathogenesis of Helicobacter pylori infection. Glycobiology (2009) 1.01