Published in Proc Natl Acad Sci U S A on July 30, 2002
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Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chem Rev (2011) 1.93
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Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains. Biochim Biophys Acta (2007) 1.86
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A (2004) 1.50
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The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer. Proc Natl Acad Sci U S A (2005) 1.32
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Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells. Proc Natl Acad Sci U S A (2005) 1.19
Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry. J Proteome Res (2009) 1.19
Development of a nanoLC LTQ orbitrap mass spectrometric method for profiling glycans derived from plasma from healthy, benign tumor control, and epithelial ovarian cancer patients. Anal Chem (2009) 1.17
Over-expression of ST3Gal-I promotes mammary tumorigenesis. Glycobiology (2010) 1.14
ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines. BMC Cancer (2009) 1.14
Functional organization of Golgi N- and O-glycosylation pathways involves pH-dependent complex formation that is impaired in cancer cells. J Biol Chem (2011) 1.14
The role of complement in tumor growth. Adv Exp Med Biol (2014) 1.11
Analysis and validation of carbohydrate three-dimensional structures. Acta Crystallogr D Biol Crystallogr (2009) 1.08
Immunoglobulin G Fc N-glycan profiling in patients with gastric cancer by LC-ESI-MS: relation to tumor progression and survival. Glycoconj J (2011) 1.08
Efficacy of glycoprotein enrichment by microscale lectin affinity chromatography. J Sep Sci (2008) 1.08
Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex. J Biol Chem (2009) 1.06
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A (2005) 1.06
The development of an integrated platform to identify breast cancer glycoproteome changes in human serum. J Chromatogr A (2009) 1.06
Functional role of gangliotetraosylceramide in epithelial-to-mesenchymal transition process induced by hypoxia and by TGF-{beta}. FASEB J (2010) 1.05
An introduction to bioinformatics for glycomics research. PLoS Comput Biol (2008) 1.05
TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo. Sci Rep (2014) 1.05
Function and 3D structure of the N-glycans on glycoproteins. Int J Mol Sci (2012) 1.04
Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process. Proc Natl Acad Sci U S A (2011) 1.03
Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers. Proc Natl Acad Sci U S A (2014) 1.02
Role of N-glycans in growth factor signaling. Glycoconj J (2004) 1.02
A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer. BMC Syst Biol (2011) 1.02
Synthetic carbohydrate-based anticancer vaccines: the Memorial Sloan-Kettering experience. Expert Rev Vaccines (2009) 1.01
A high-throughput O-glycopeptide discovery platform for seromic profiling. J Proteome Res (2010) 1.00
Enhanced sensitivity of LC-MS analysis of permethylated N-glycans through online purification. Electrophoresis (2011) 0.99
Glycosylation in bladder cancer. Int J Clin Oncol (2008) 0.99
Integration of glycosphingolipid metabolism and cell-fate decisions in cancer and stem cells: review and hypothesis. Glycoconj J (2004) 0.97
Leczyme: a new candidate drug for cancer therapy. Biomed Res Int (2014) 0.97
Gangliosides play an important role in the organization of CD82-enriched microdomains. Biochem J (2006) 0.96
Knockdown of GnT-Va expression inhibits ligand-induced downregulation of the epidermal growth factor receptor and intracellular signaling by inhibiting receptor endocytosis. Glycobiology (2009) 0.96
Altered expression of sialylated glycoproteins in breast cancer using hydrazide chemistry and mass spectrometry. Mol Cell Proteomics (2012) 0.95
Regulation of homotypic cell-cell adhesion by branched N-glycosylation of N-cadherin extracellular EC2 and EC3 domains. J Biol Chem (2009) 0.95
Glycosphingolipids and cell death. Glycoconj J (2004) 0.95
Carbohydrate sequence of the prostate cancer-associated antigen F77 assigned by a mucin O-glycome designer array. J Biol Chem (2014) 0.94
Specific posttranslational modification regulates early events in mammary carcinoma formation. Proc Natl Acad Sci U S A (2010) 0.93
Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumor. Mol Cell Proteomics (2010) 0.93
N-Glycan structure annotation of glycopeptides using a linearized glycan structure database (GlyDB). J Proteome Res (2007) 0.93
Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array. Int J Cancer (2011) 0.92
Alternate routes for drug delivery to the cell interior: pathways to the Golgi apparatus and endoplasmic reticulum. Adv Drug Deliv Rev (2007) 0.92
Serum antibodies to blood group A predict survival on PROSTVAC-VF. Clin Cancer Res (2013) 0.92
Alterations in human breast cancer adhesion-motility in response to changes in cell surface glycoproteins displaying alpha-L-fucose moieties. Int J Oncol (2008) 0.92
Sweet and sour: the impact of differential glycosylation in cancer cells undergoing epithelial-mesenchymal transition. Front Oncol (2014) 0.92
Differential N-glycosylation of kallikrein 6 derived from ovarian cancer cells or the central nervous system. Mol Cell Proteomics (2008) 0.91
Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer. Front Oncol (2015) 0.91
Thin layer chromatography of gangliosides. Glycoconj J (2009) 0.91
Aberrant expression of sialidase and cancer progression. Proc Jpn Acad Ser B Phys Biol Sci (2008) 0.91
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities. J Cancer Res Clin Oncol (2007) 0.91
Humoral response to a viral glycan correlates with survival on PROSTVAC-VF. Proc Natl Acad Sci U S A (2014) 0.91
Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche. Cancer Discov (2014) 0.90
Cancer associated aberrant protein O-glycosylation can modify antigen processing and immune response. PLoS One (2012) 0.90
Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case–control study of colorectal cancer in UK collaborative trial of ovarian cancer screening. Int J Cancer (2014) 0.89
Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis. Biochem J (2005) 0.89
The sweet and sour of serological glycoprotein tumor biomarker quantification. BMC Med (2013) 0.88
NEU3 sialidase strictly modulates GM3 levels in skeletal myoblasts C2C12 thus favoring their differentiation and protecting them from apoptosis. J Biol Chem (2008) 0.88
Mass spectrometry-based identification of the tumor antigen UN1 as the transmembrane CD43 sialoglycoprotein. Mol Cell Proteomics (2011) 0.88
Targeting the immune system in non-small-cell lung cancer: bridging the gap between promising concept and therapeutic reality. Clin Lung Cancer (2010) 0.88
A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells. J Biol Chem (2011) 0.87
A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity. Glycoconj J (2004) 0.87
Increase of O-glycosylated oncofetal fibronectin in high glucose-induced epithelial-mesenchymal transition of cultured human epithelial cells. PLoS One (2013) 0.87
Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4. J Biol Chem (2011) 0.87
Sialylated Lewis x antigen bearing glycoproteins in human plasma. J Proteome Res (2010) 0.87
Loss of expression of N-acetylglucosaminyltransferase Va results in altered gene expression of glycosyltransferases and galectins. FEBS Lett (2008) 0.87
Comparative glycomic profiling of isotopically permethylated N-glycans by liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom (2013) 0.87
Label-free quantitative proteomics and N-glycoproteomics analysis of KRAS-activated human bronchial epithelial cells. Mol Cell Proteomics (2012) 0.87
A Comprehensive Review of Dysregulated miRNAs Involved in Cervical Cancer. Curr Genomics (2014) 0.86
Plasma membrane-associated sialidase (NEU3) regulates progression of prostate cancer to androgen-independent growth through modulation of androgen receptor signaling. Cell Death Differ (2011) 0.86
Targeted drug delivery to tumor vasculature by a carbohydrate mimetic peptide. Proc Natl Acad Sci U S A (2011) 0.86
Identification of mRNA splicing factors as the endothelial receptor for carbohydrate-dependent lung colonization of cancer cells. Proc Natl Acad Sci U S A (2009) 0.86
Hallmarks of glycosylation in cancer. Oncotarget (2016) 0.86
Multidimensional liquid chromatography platform for profiling alterations of clusterin N-glycosylation in the plasma of patients with renal cell carcinoma. J Chromatogr A (2012) 0.85
Tracking surface glycans on live cancer cells with single-molecule sensitivity. Angew Chem Int Ed Engl (2014) 0.85
One-Year Plasma N-linked Glycome Intra-individual and Inter-individual Variability in the Chicken Model of Spontaneous Ovarian Adenocarcinoma. Int J Mass Spectrom (2011) 0.85
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker. BMC Cancer (2005) 0.85
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer. Oncotarget (2015) 0.85
Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells. PLoS One (2013) 0.84
Cyclooxygenase-2 enzyme induces the expression of the α-2,3-sialyltransferase-3 (ST3Gal-I) in breast cancer. J Biol Chem (2012) 0.84
Induction of epithelial-mesenchymal transition with O-glycosylated oncofetal fibronectin. FEBS Lett (2012) 0.84
The pleiotropic roles of sphingolipid signaling in autophagy. Cell Death Dis (2014) 0.84
Immunology in the clinic review series; focus on cancer: glycolipids as targets for tumour immunotherapy. Clin Exp Immunol (2012) 0.84
Interactome mapping: using protein microarray technology to reconstruct diverse protein networks. Genomics Proteomics Bioinformatics (2013) 0.84
Analysis of the expression of human tumor antigens in ovarian cancer tissues. Cancer Biomark (2010) 0.84
Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients. Clin Pharmacol Ther (2014) 0.84
A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. J Lipid Res (2011) 0.84
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Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor. J Biol Chem (1986) 2.00
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Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer. Glycoconj J (1997) 1.54
Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X. J Biol Chem (1998) 1.48
Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection. Proc Natl Acad Sci U S A (1995) 1.44
Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis. J Biol Chem (1996) 1.44
Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression. Proc Natl Acad Sci U S A (2002) 1.44
Dual roles of sialyl Lewis X oligosaccharides in tumor metastasis and rejection by natural killer cells. EMBO J (1999) 1.42
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Differential display cloning identifies motility-related protein (MRP1/CD9) as highly expressed in primary compared to metastatic human colon carcinoma cells. Cancer Res (1997) 1.39
Prometastatic effect of N-acetylglucosaminyltransferase V is due to modification and stabilization of active matriptase by adding beta 1-6 GlcNAc branching. J Biol Chem (2002) 1.30
Motility inhibition and apoptosis are induced by metastasis-suppressing gene product CD82 and its analogue CD9, with concurrent glycosylation. Cancer Res (1999) 1.26
GM3 ganglioside inhibits CD9-facilitated haptotactic cell motility: coexpression of GM3 and CD9 is essential in the downregulation of tumor cell motility and malignancy. Biochemistry (2001) 1.26
New aspects of siglec binding specificities, including the significance of fucosylation and of the sialyl-Tn epitope. Sialic acid-binding immunoglobulin superfamily lectins. J Biol Chem (2000) 1.20
Tetraspanin CD9 is a "proteolipid," and its interaction with alpha 3 integrin in microdomain is promoted by GM3 ganglioside, leading to inhibition of laminin-5-dependent cell motility. J Biol Chem (2002) 1.15
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Gangliosides influence angiogenesis in an experimental mouse brain tumor. Cancer Res (1999) 1.04
A secreted type of beta 1,6-N-acetylglucosaminyltransferase V (GnT-V) induces tumor angiogenesis without mediation of glycosylation: a novel function of GnT-V distinct from the original glycosyltransferase activity. J Biol Chem (2002) 1.02
Epidermal growth factor receptor glycosylation is required for ganglioside GM3 binding and GM3-mediated suppression [correction of suppresion] of activation. Glycobiology (2001) 1.02
Suppression of ganglioside GD3 expression in a rat F-11 tumor cell line reduces tumor growth, angiogenesis, and vascular endothelial growth factor production. Cancer Res (2000) 1.01
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Enhanced GM3 expression, associated with decreased invasiveness, is induced by brefeldin A in bladder cancer cells. Int J Oncol (2001) 0.94
P- and E-selectins recognize sialyl 6-sulfo Lewis X, the recently identified L-selectin ligand. Biochem Biophys Res Commun (2000) 0.94
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