PubRank

Daniel Finley

Author PubWeight™ 122.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A proteomics approach to understanding protein ubiquitination. Nat Biotechnol 2003 10.51
2 Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 2009 6.16
3 Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature 2010 5.08
4 Multiple associated proteins regulate proteasome structure and function. Mol Cell 2002 4.97
5 Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 2008 4.76
6 Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell 2007 4.54
7 Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology. Nat Cell Biol 2006 4.25
8 Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat Cell Biol 2002 4.06
9 A ubiquitin stress response induces altered proteasome composition. Cell 2007 3.82
10 Delivery of ubiquitinated substrates to protein-unfolding machines. Nat Cell Biol 2005 3.38
11 Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 2002 3.34
12 Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. Cell 2006 3.21
13 Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature 2008 3.11
14 Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. Cell 2006 2.87
15 Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome. J Biol Chem 2004 2.85
16 Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell 2009 2.75
17 Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Mol Cell Biol 2003 2.29
18 Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome. Mol Cell 2010 2.13
19 Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature 2009 2.07
20 Proteasome-associated proteins: regulation of a proteolytic machine. Biol Chem 2005 2.01
21 Hexameric assembly of the proteasomal ATPases is templated through their C termini. Nature 2009 1.97
22 Characterization of the proteasome using native gel electrophoresis. Methods Enzymol 2005 1.89
23 Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites. Nat Struct Mol Biol 2007 1.89
24 A proteasome for all occasions. FEBS Lett 2007 1.84
25 Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes. Mol Cell Proteomics 2010 1.79
26 The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol 2005 1.78
27 Localization to the proteasome is sufficient for degradation. J Biol Chem 2004 1.72
28 Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell 2009 1.61
29 Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression. J Biol Chem 2004 1.58
30 Regulation of proteasome activity in health and disease. Biochim Biophys Acta 2013 1.52
31 Purification of proteasomes, proteasome subcomplexes, and proteasome-associated proteins from budding yeast. Methods Mol Biol 2005 1.48
32 Malfolded protein structure and proteostasis in lung diseases. Am J Respir Crit Care Med 2014 1.47
33 APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nat Cell Biol 2012 1.46
34 Proteasome disassembly and downregulation is correlated with viability during stationary phase. Curr Biol 2003 1.44
35 An asymmetric interface between the regulatory and core particles of the proteasome. Nat Struct Mol Biol 2011 1.36
36 Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2. Mol Cell 2010 1.29
37 Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem 2005 1.26
38 Ubiquitin homeostasis is critical for synaptic development and function. J Neurosci 2011 1.26
39 Role of a ubiquitin-like modification in polarized morphogenesis. Science 2002 1.06
40 Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress response. J Biol Chem 2011 1.04
41 Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism. J Biol Chem 2011 1.01
42 Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. J Clin Invest 2014 1.00
43 Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast. Curr Biol 2004 0.98
44 Rpn6p, a proteasome subunit from Saccharomyces cerevisiae, is essential for the assembly and activity of the 26 S proteasome. J Biol Chem 2002 0.97
45 Reconfiguration of the proteasome during chaperone-mediated assembly. Nature 2013 0.96
46 Assembly manual for the proteasome regulatory particle: the first draft. Biochem Soc Trans 2010 0.91
47 Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins. BMC Biochem 2008 0.88
48 Conformational dynamics of the Rpt6 ATPase in proteasome assembly and Rpn14 binding. Structure 2013 0.87
49 A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication. Virus Res 2012 0.87
50 Cuz1/Ynl155w, a zinc-dependent ubiquitin-binding protein, protects cells from metalloid-induced proteotoxicity. J Biol Chem 2013 0.83
51 Ubiquitin chained and crosslinked. Nat Cell Biol 2002 0.83
52 A High-Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14. Curr Protoc Chem Biol 2012 0.83
53 Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1. J Biol Chem 2014 0.82
54 Spg5 protein regulates the proteasome in quiescence. J Biol Chem 2012 0.80
55 Cell biology: Destruction deconstructed. Nature 2012 0.78
56 Binding of ubiquitin conjugates to proteasomes as visualized with native gels. Methods Mol Biol 2012 0.78
57 Cell biology. An ancient portal to proteolysis. Science 2012 0.77
58 Misfolded proteins driven to destruction by Hul5. Nat Cell Biol 2011 0.76
59 Varshavsky's contributions. Science 2004 0.75