Published in Mol Neurobiol on December 02, 2011
Presynaptic Active Zone Density during Development and Synaptic Plasticity. Front Mol Neurosci (2012) 0.88
Role of exercise in maintaining the integrity of the neuromuscular junction. Muscle Nerve (2013) 0.86
Loss of β2-laminin alters calcium sensitivity and voltage-gated calcium channel maturation of neurotransmission at the neuromuscular junction. J Physiol (2014) 0.86
Active zones of mammalian neuromuscular junctions: formation, density, and aging. Ann N Y Acad Sci (2012) 0.83
Altered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravis. PLoS One (2014) 0.77
The role of laminins in the organization and function of neuromuscular junctions. Matrix Biol (2016) 0.76
Improvement of Eye Alignment in Adult Strabismic Monkeys by Sustained IGF-1 Treatment. Invest Ophthalmol Vis Sci (2016) 0.75
Synaptic Homeostasis and Its Immunological Disturbance in Neuromuscular Junction Disorders. Int J Mol Sci (2017) 0.75
alpha-Synuclein locus triplication causes Parkinson's disease. Science (2003) 20.20
Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol (2000) 9.88
A study of synaptic transmission in the absence of nerve impulses. J Physiol (1967) 9.73
Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release. J Cell Biol (1979) 8.78
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet (2004) 7.69
Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release. Neuron (1998) 5.96
Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science (2000) 5.89
Development of the vertebrate neuromuscular junction. Annu Rev Neurosci (1999) 5.81
Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. Nature (2003) 5.19
Induction, assembly, maturation and maintenance of a postsynaptic apparatus. Nat Rev Neurosci (2001) 5.10
Microdomains of high calcium concentration in a presynaptic terminal. Science (1992) 5.09
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron (2010) 4.76
The timing of calcium action during neuromuscular transmission. J Physiol (1967) 4.72
Dystroglycan: from biosynthesis to pathogenesis of human disease. J Cell Sci (2006) 3.92
Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell (1996) 3.88
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo. Cell (1996) 3.81
Primary structure and functional expression from complementary DNA of a brain calcium channel. Nature (1991) 3.77
Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature (1997) 3.63
Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons. Neuron (1989) 3.45
Lrp4 is a receptor for Agrin and forms a complex with MuSK. Cell (2008) 3.29
The presynaptic active zone protein bassoon is essential for photoreceptor ribbon synapse formation in the retina. Neuron (2003) 3.16
LRP4 serves as a coreceptor of agrin. Neuron (2008) 2.98
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins. J Neurosci (1996) 2.93
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc Natl Acad Sci U S A (2002) 2.91
RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell (2011) 2.90
P-type calcium channels blocked by the spider toxin omega-Aga-IVA. Nature (1992) 2.83
Agrin acts via a MuSK receptor complex. Cell (1996) 2.81
A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction. Nature (1989) 2.79
Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse. Nature (2001) 2.77
Quantal components of end-plate potentials in the myasthenic syndrome. Ann N Y Acad Sci (1971) 2.73
[Synaptic vesicles and pouches at the level of "active zones" of the neuromuscular junction]. C R Acad Sci Hebd Seances Acad Sci D (1970) 2.72
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron (1998) 2.68
Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. J Biol Chem (1995) 2.68
Synaptic development: insights from Drosophila. Curr Opin Neurobiol (2007) 2.67
Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Hum Mol Genet (2004) 2.67
Genetic evidence that relative synaptic efficacy biases the outcome of synaptic competition. Nature (2003) 2.51
Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. J Cell Biol (2005) 2.48
Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2. Nature (1995) 2.47
Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron (2005) 2.46
Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature (1995) 2.46
Maturation of active zone assembly by Drosophila Bruchpilot. J Cell Biol (2009) 2.34
Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J Cell Biol (1990) 2.33
Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon. Neuron (2003) 2.31
Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals. J Cell Biol (1998) 2.30
RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone. Neuron (2011) 2.29
The architecture of active zone material at the frog's neuromuscular junction. Nature (2001) 2.26
Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J Cell Biol (1997) 2.25
Are the presynaptic membrane particles the calcium channels? Proc Natl Acad Sci U S A (1981) 2.22
Mutation of the calcium channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina. Hum Mol Genet (2005) 2.22
LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development (2006) 2.22
A complete genetic analysis of neuronal Rab3 function. J Neurosci (2004) 2.21
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. J Neurosci (2005) 2.21
Three-dimensional reconstruction of a calyx of Held and its postsynaptic principal neuron in the medial nucleus of the trapezoid body. J Neurosci (2002) 2.17
Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase. Neuron (2002) 2.16
Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses. Neuron (1990) 2.15
Identification of a syntaxin-binding site on N-type calcium channels. Neuron (1994) 2.09
Rab3 dynamically controls protein composition at active zones. Neuron (2009) 2.07
Expression of several adhesive macromolecules (N-CAM, L1, J1, NILE, uvomorulin, laminin, fibronectin, and a heparan sulfate proteoglycan) in embryonic, adult, and denervated adult skeletal muscle. J Cell Biol (1986) 2.07
Neuropathology in mice expressing human alpha-synuclein. J Neurosci (2000) 2.06
Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron (2000) 2.04
Calcium-dependent interaction of N-type calcium channels with the synaptic core complex. Nature (1996) 2.03
Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. Cell (2007) 2.00
Studies of excitable membranes. II. A comparison of specializations at neuromuscular junctions and nonjunctional sarcolemmas of mammalian fast and slow twitch muscle fibers. J Cell Biol (1976) 1.97
Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling. Neuron (2010) 1.95
RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nat Neurosci (2007) 1.95
Molecular mechanisms of presynaptic differentiation. Annu Rev Cell Dev Biol (2008) 1.94
Hts/Adducin controls synaptic elaboration and elimination. Neuron (2011) 1.93
Structure and functional expression of an omega-conotoxin-sensitive human N-type calcium channel. Science (1992) 1.91
A synaptic laminin-calcium channel interaction organizes active zones in motor nerve terminals. Nature (2004) 1.89
The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse. Neuron (1988) 1.87
Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J Biol Chem (2001) 1.86
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J (2005) 1.86
Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. Proc Natl Acad Sci U S A (2010) 1.85
Regulation of transmitter release by Unc-13 and its homologues. Curr Opin Neurobiol (2000) 1.83
P-type voltage-dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses. Proc Natl Acad Sci U S A (1992) 1.82
Three-dimensional architecture of presynaptic terminal cytomatrix. J Neurosci (2007) 1.82
Integrins as receptors for laminins. Microsc Res Tech (2000) 1.81
Altered synaptic development and active zone spacing in endocytosis mutants. Curr Biol (2006) 1.79
Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel. Proc Natl Acad Sci U S A (1992) 1.77
Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J Neurosci (2003) 1.75
Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter. Proc Natl Acad Sci U S A (2005) 1.75
Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels. EMBO J (1996) 1.75
Association of neuronal calcium channels with modular adaptor proteins. J Biol Chem (1999) 1.75
Antibodies that bind specifically to synaptic sites on muscle fiber basal lamina. J Cell Biol (1979) 1.75
Deletion of CASK in mice is lethal and impairs synaptic function. Proc Natl Acad Sci U S A (2007) 1.74
Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones. Proc Natl Acad Sci U S A (1983) 1.71
Bassoon speeds vesicle reloading at a central excitatory synapse. Neuron (2010) 1.67
The calcium channel and the organization of the presynaptic transmitter release face. Trends Neurosci (1997) 1.67
Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis. J Biol Chem (2003) 1.66
Piccolo, a presynaptic zinc finger protein structurally related to bassoon. Neuron (2000) 1.66
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1. J Cell Biol (2002) 1.65
Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci (2009) 1.65
A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones. Proc Natl Acad Sci U S A (2002) 1.62
Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction. Neuron (1999) 1.60
Localization of Ca2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals. J Neurosci (1998) 1.59
Primary structure of a calcium channel that is highly expressed in the rat cerebellum. Proc Natl Acad Sci U S A (1991) 1.59
Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons. J Neurosci (2010) 1.57
Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25. Proc Natl Acad Sci U S A (1996) 1.56
Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. EMBO J (2006) 1.53