Published in Biochemistry on December 28, 2011
Structural and dynamical features of inteins and implications on protein splicing. J Biol Chem (2014) 0.98
Protein splicing: how inteins escape from precursor proteins. J Biol Chem (2014) 0.97
Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases. Proc Natl Acad Sci U S A (2002) 1.64
The naturally split Npu DnaE intein exhibits an extraordinarily high rate in the protein trans-splicing reaction. FEBS Lett (2009) 1.63
The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis. Cell Host Microbe (2013) 1.44
Large-scale quantitative assessment of different in-solution protein digestion protocols reveals superior cleavage efficiency of tandem Lys-C/trypsin proteolysis over trypsin digestion. J Proteome Res (2012) 1.32
Regulation of yeast central metabolism by enzyme phosphorylation. Mol Syst Biol (2012) 1.15
Chemically induced and light-independent cryptochrome photoreceptor activation. Mol Plant (2007) 1.09
Recent progress in intein research: from mechanism to directed evolution and applications. Cell Mol Life Sci (2012) 1.03
Highly efficient and more general cis- and trans-splicing inteins through sequential directed evolution. J Biol Chem (2011) 1.01
Ligation of a synthetic peptide to the N terminus of a recombinant protein using semisynthetic protein trans-splicing. Angew Chem Int Ed Engl (2006) 1.01
Automatic generation of predictive dynamic models reveals nuclear phosphorylation as the key Msn2 control mechanism. Sci Signal (2013) 1.00
Interaction studies and alanine scanning analysis of a semi-synthetic split intein reveal thiazoline ring formation from an intermediate of the protein splicing reaction. J Biol Chem (2008) 0.99
Engineering artificially split inteins for applications in protein chemistry: biochemical characterization of the split Ssp DnaB intein and comparison to the split Sce VMA intein. Biochemistry (2006) 0.98
In vivo production of artificial nonribosomal peptide products in the heterologous host Escherichia coli. Appl Environ Microbiol (2004) 0.97
Generation of site-specific and enzymatically stable conjugates of recombinant proteins with ubiquitin-like modifiers by the Cu(I)-catalyzed azide-alkyne cycloaddition. Chembiochem (2010) 0.94
Unprecedented rates and efficiencies revealed for new natural split inteins from metagenomic sources. J Biol Chem (2012) 0.94
Click synthesis of ubiquitin dimer analogs to interrogate linkage-specific UBA domain binding. Chem Commun (Camb) (2011) 0.94
Temporomandibular joint disk position assessed at coronal MR imaging in asymptomatic volunteers. Radiology (2005) 0.90
Photocontrol of protein activity mediated by the cleavage reaction of a split intein. Angew Chem Int Ed Engl (2011) 0.90
Site-specific chemical modification of proteins with a prelabelled cysteine tag using the artificially split Mxe GyrA intein. Chembiochem (2008) 0.90
Expanded click conjugation of recombinant proteins with ubiquitin-like modifiers reveals altered substrate preference of SUMO2-modified Ubc9. Angew Chem Int Ed Engl (2011) 0.90
Modification of transmembrane and GPI-anchored proteins on living cells by efficient protein trans-splicing using the Npu DnaE intein. Chem Commun (Camb) (2011) 0.88
Systematic and quantitative analysis of protein-protein recognition between nonribosomal peptide synthetases investigated in the tyrocidine biosynthetic template. Biochemistry (2003) 0.88
Regioselective cysteine bioconjugation by appending a labeled cystein tag to a protein by using protein splicing in trans. Angew Chem Int Ed Engl (2007) 0.87
Statistical approach to protein quantification. Mol Cell Proteomics (2013) 0.86
Bioorthogonal ligation in the spotlight. Angew Chem Int Ed Engl (2009) 0.85
An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing. Mol Biosyst (2011) 0.84
Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol-alkyne addition. Bioorg Med Chem (2013) 0.84
Generation of a genetically encoded, photoactivatable intein for the controlled production of cyclic peptides. Angew Chem Int Ed Engl (2014) 0.83
Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases. FEBS J (2010) 0.81
Expanding the scope of protein trans-splicing to fragment ligation of an integral membrane protein: towards modulation of porin-based ion channels by chemical modification. Chembiochem (2009) 0.79
Structure-activity studies on the upstream splice junction of a semisynthetic intein. Bioorg Med Chem (2013) 0.78
Design of an intein that can be inhibited with a small molecule ligand. J Am Chem Soc (2005) 0.78
An atypical naturally split intein engineered for highly efficient protein labeling. Angew Chem Int Ed Engl (2014) 0.78
Semisynthesis of proteins using split inteins. Methods Enzymol (2009) 0.77
Chemical bypass of intein-catalyzed N-S acyl shift in protein splicing. Angew Chem Int Ed Engl (2013) 0.77
Numerical construction of estimators for single-molecule fluorescence measurements. J Phys Chem B (2013) 0.77
Chemical-tag labeling of proteins using fully recombinant split inteins. Methods Mol Biol (2015) 0.77
Protein trans-splicing on an M13 bacteriophage: towards directed evolution of a semisynthetic split intein by phage display. J Pept Sci (2010) 0.77
Applications and Developments in Targeted Proteomics: From SRM to DIA/SWATH. Proteomics (2016) 0.76
Kinetics profiling of gramicidin S synthetase A, a member of nonribosomal peptide synthetases. Biochemistry (2014) 0.76
SPLICEFINDER - a fast and easy screening method for active protein trans-splicing positions. PLoS One (2013) 0.75
Ligation of synthetic peptides to proteins using semisynthetic protein trans-splicing. Methods Mol Biol (2015) 0.75
Extending the scope of site-specific cysteine bioconjugation by appending a prelabeled cysteine tag to proteins using protein trans-splicing. Methods Mol Biol (2011) 0.75
Probing the molecular basis of protein function through chemistry. Chembiochem (2006) 0.75
Development of a screening system for inteins active in protein splicing based on intein insertion into the LacZα-peptide. Biol Chem (2017) 0.75
Click-tag and amine-tag: chemical tag approaches for efficient protein labeling in vitro and on live cells using the naturally split Npu DnaE intein. Angew Chem Int Ed Engl (2014) 0.75