Published in Free Radic Biol Med on December 01, 2011
8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. Free Radic Biol Med (2013) 1.05
Oxidative stress damage as a detrimental factor in preterm birth pathology. Front Immunol (2014) 1.03
The role of 8-oxoguanine DNA glycosylase-1 in inflammation. Int J Mol Sci (2014) 0.86
Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling. Free Radic Biol Med (2015) 0.79
8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: role in asthma pathogenesis. Curr Opin Allergy Clin Immunol (2015) 0.79
The basic chemistry of exercise-induced DNA oxidation: oxidative damage, redox signaling, and their interplay. Front Physiol (2015) 0.78
8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging. Mech Ageing Dev (2016) 0.76
Hydrogen peroxide sensing and signaling. Mol Cell (2007) 6.24
A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. Anal Biochem (1997) 5.23
Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine. Proc Natl Acad Sci U S A (1990) 4.06
Free radical-induced damage to DNA: mechanisms and measurement. Free Radic Biol Med (2002) 3.18
Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation. Nat Chem Biol (2006) 3.08
ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest (2005) 2.34
One-electron oxidation of DNA and inflammation processes. Nat Chem Biol (2006) 2.27
Repair of endogenous DNA damage. Cold Spring Harb Symp Quant Biol (2000) 2.24
Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA. Nucleic Acids Res (2002) 1.82
Formation of an 8-hydroxyguanine moiety in deoxyribonucleic acid on gamma-irradiation in aqueous solution. Biochemistry (1985) 1.78
Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine. Anal Biochem (1994) 1.76
8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells. Proc Natl Acad Sci U S A (2008) 1.47
Choreography of oxidative damage repair in mammalian genomes. Free Radic Biol Med (2002) 1.43
Base-excision repair of oxidative DNA damage by DNA glycosylases. Mutat Res (2005) 1.34
Reaction of HO* with guanine derivatives in aqueous solution: formation of two different redox-active OH-adduct radicals and their unimolecular transformation reactions. Properties of G(-H)*. Chemistry (2000) 1.28
Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species. J Biol Chem (2005) 1.22
The level and half-life of glutathione in human plasma. FEBS Lett (1980) 1.21
8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress. Free Radic Biol Med (2010) 1.20
Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects. Free Radic Biol Med (2008) 1.17
Guanosine and inosine display antioxidant activity, protect DNA in vitro from oxidative damage induced by reactive oxygen species, and serve as radioprotectors in mice. Radiat Res (2006) 1.12
BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection. Free Radic Biol Med (2001) 1.10
Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA. Free Radic Biol Med (2002) 1.10
Increased ROS generation in subsets of OGG1 knockout fibroblast cells. Mech Ageing Dev (2007) 1.04
Characterization of 5-hydroxy-8-oxo-7,8-dihydroguanosine in the photosensitized oxidation of 8-oxo-7,8-dihydroguanosine and its rearrangement to spiroiminodihydantoin. J Am Chem Soc (2004) 1.01
Measurement of 8-hydroxy-2'-deoxyguanosine in DNA by high-performance liquid chromatography-mass spectrometry: comparison with measurement by gas chromatography-mass spectrometry. Nucleic Acids Res (2001) 1.01
Potential mechanisms for the inhibition of tumor cell growth by manganese superoxide dismutase. Antioxid Redox Signal (2001) 1.01
Guanine oxidation: one- and two-electron reactions. Chemistry (2006) 0.99
Selective induction of manganous superoxide dismutase in human monocytes. Am J Physiol (1985) 0.97
Localization of superoxide anion production to mitochondrial electron transport chain in 3-NPA-treated cells. Mitochondrion (2006) 0.95
Cadmium resistance in A549 cells correlates with elevated glutathione content but not antioxidant enzymatic activities. Free Radic Biol Med (1995) 0.92
Measurement of formamidopyrimidines in DNA. Free Radic Biol Med (2008) 0.92
A novel R229Q OGG1 polymorphism results in a thermolabile enzyme that sensitizes KG-1 leukemia cells to DNA damaging agents. Cancer Detect Prev (2007) 0.91
The role of glutathione metabolism in the detoxification of H2O2 in rabbit lens. Invest Ophthalmol Vis Sci (1982) 0.89
Enhanced gamma-glutamylcysteine synthetase activity decreases drug-induced oxidative stress levels and cytotoxicity. Mol Carcinog (2006) 0.88
8-Oxoguanine induces intramolecular DNA damage but free 8-oxoguanine protects intermolecular DNA from oxidative stress. FEBS Lett (2004) 0.86
Urinary 8-hydroxyguanine may be a better marker of oxidative stress than 8-hydroxydeoxyguanosine in relation to the life spans of various species. Antioxid Redox Signal (2006) 0.85
Electronic structure of DNA--unique properties of 8-oxoguanosine. J Am Chem Soc (2009) 0.83
A novel method using 8-hydroperoxy-2'-deoxyguanosine formation for evaluating antioxidative potency. Free Radic Res (2002) 0.82
Photosensitized formation of 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in DNA by riboflavin. Nucleic Acids Symp Ser (1992) 0.81
Mechanistic aspects of the oxidation of DNA constituents mediated by singlet molecular oxygen. Arch Biochem Biophys (2004) 0.81
Electron transfer processes in DNA: mechanisms, biological relevance and applications in DNA analytics. Nat Prod Rep (2006) 0.78
Oxidation of human catalase by singlet oxygen in myeloid leukemia cells. Photochem Photobiol (1999) 0.77
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res (2008) 3.48
AP endonuclease-independent DNA base excision repair in human cells. Mol Cell (2004) 3.37
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proc Natl Acad Sci U S A (2002) 3.33
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions. J Biol Chem (2002) 2.54
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. J Biol Chem (2003) 2.53
ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest (2005) 2.34
Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene. EMBO J (2003) 1.94
RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes. Mol Cell Biol (2008) 1.91
Inactivation of hnRNP K by expanded intronic AUUCU repeat induces apoptosis via translocation of PKCdelta to mitochondria in spinocerebellar ataxia 10. PLoS Genet (2010) 1.76
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes. J Biol Chem (2007) 1.63
STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen. Gastroenterology (2005) 1.56
Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage. Toxicology (2003) 1.52
Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo. Mol Cell Biol (2006) 1.48
TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway. Cell Signal (2007) 1.47
Mitochondrial dysfunction increases allergic airway inflammation. J Immunol (2009) 1.46
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. DNA Repair (Amst) (2006) 1.45
Choreography of oxidative damage repair in mammalian genomes. Free Radic Biol Med (2002) 1.43
CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation. J Immunol (2002) 1.41
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1. J Biol Chem (2007) 1.38
Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells. Nucleic Acids Res (2006) 1.36
Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress. J Biol Chem (2007) 1.32
Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells. Infect Immun (2007) 1.32
Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine. J Biol Chem (2012) 1.30
Endurance exercise increases the SIRT1 and peroxisome proliferator-activated receptor gamma coactivator-1alpha protein expressions in rat skeletal muscle. Metabolism (2008) 1.30
Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats. Mech Ageing Dev (2009) 1.29
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. J Biol Chem (2008) 1.27
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. Proc Natl Acad Sci U S A (2003) 1.26
Unc119, a novel activator of Lck/Fyn, is essential for T cell activation. J Exp Med (2004) 1.25
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat Immunol (2009) 1.25
Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. Mol Cell Biol (2008) 1.24
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol (2009) 1.24
Functional analysis of the nuclear proteome of human A549 alveolar epithelial cells by HPLC-high resolution 2-D gel electrophoresis. Proteomics (2006) 1.23
Subpollen particles: carriers of allergenic proteins and oxidases. J Allergy Clin Immunol (2006) 1.23
Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein. DNA Repair (Amst) (2006) 1.23
Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species. J Biol Chem (2005) 1.22
Exercise plays a preventive role against Alzheimer's disease. J Alzheimers Dis (2010) 1.22
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells. J Biol Chem (2010) 1.22
8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress. Free Radic Biol Med (2010) 1.20
Serum brain-derived neurotrophic factor level is increased and associated with obesity in newly diagnosed female patients with type 2 diabetes mellitus. Metabolism (2006) 1.20
Traumatic brain injury: oxidative stress and neuroprotection. Antioxid Redox Signal (2013) 1.18
MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation. J Exp Med (2007) 1.18
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem (2011) 1.18
Helicobacter pylori and H2O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells. Gastroenterology (2004) 1.18
Respiratory syncytial virus infection induces a reactive oxygen species-MSK1-phospho-Ser-276 RelA pathway required for cytokine expression. J Virol (2009) 1.17
Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice. Atherosclerosis (2006) 1.15
Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity. Nucleic Acids Res (2004) 1.15
Thirdhand smoke causes DNA damage in human cells. Mutagenesis (2013) 1.14
The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase. Nucleic Acids Res (2007) 1.14
Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases. Mech Ageing Dev (2012) 1.13
Resveratrol enhances exercise training responses in rats selectively bred for high running performance. Food Chem Toxicol (2013) 1.12
Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution. Nucleic Acids Res (2008) 1.12
Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases. Biochemistry (2004) 1.12
Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice. PLoS One (2009) 1.11
Effect of pollen-mediated oxidative stress on immediate hypersensitivity reactions and late-phase inflammation in allergic conjunctivitis. J Allergy Clin Immunol (2005) 1.10
Liver gene expression associated with diet and lesion development in atherosclerosis-prone mice: induction of components of alternative complement pathway. Physiol Genomics (2004) 1.08
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases. J Biol Chem (2002) 1.08
Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair. DNA Repair (Amst) (2013) 1.08
Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases. J Biol Chem (2010) 1.06
8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. Free Radic Biol Med (2013) 1.05
Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation. J Allergy Clin Immunol (2007) 1.05
Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress. Toxicology (2003) 1.04
Increased ROS generation in subsets of OGG1 knockout fibroblast cells. Mech Ageing Dev (2007) 1.04
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins. Proc Natl Acad Sci U S A (2013) 1.04
Aeromonas hydrophila cytotoxic enterotoxin activates mitogen-activated protein kinases and induces apoptosis in murine macrophages and human intestinal epithelial cells. J Biol Chem (2004) 1.04
Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats. Exp Gerontol (2007) 1.03
Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein. J Biol Chem (2004) 1.02
Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training. Am J Physiol Regul Integr Comp Physiol (2012) 1.02
Oxidative stress induces the expression of Fas and Fas ligand and apoptosis in murine intestinal epithelial cells. Free Radic Biol Med (2002) 1.01
3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells. Brain Res Mol Brain Res (2005) 1.01
RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures. DNA Repair (Amst) (2010) 1.00