Published in J Biol Chem on November 21, 2007
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res (2008) 3.48
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 1.61
Minimizing the damage: repair pathways keep mitochondrial DNA intact. Nat Rev Mol Cell Biol (2012) 1.30
Recent advances in the structural mechanisms of DNA glycosylases. Biochim Biophys Acta (2012) 1.30
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. J Biol Chem (2008) 1.27
Base excision repair and cancer. Cancer Lett (2012) 1.23
The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage. Prog Mol Biol Transl Sci (2012) 1.22
Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts. Biochemistry (2010) 1.18
RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1. Proc Natl Acad Sci U S A (2010) 1.17
Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases. Mech Ageing Dev (2012) 1.13
Oxidative genome damage and its repair in neurodegenerative diseases: function of transition metals as a double-edged sword. J Alzheimers Dis (2011) 1.13
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. J Biol Chem (2009) 1.12
Loading clamps for DNA replication and repair. DNA Repair (Amst) (2009) 1.12
Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases. J Biol Chem (2010) 1.06
Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context. J Biol Chem (2013) 1.05
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins. Proc Natl Acad Sci U S A (2013) 1.04
Rules of engagement for base excision repair in chromatin. J Cell Physiol (2013) 1.03
Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1. DNA Repair (Amst) (2009) 1.01
The human oxidative DNA glycosylase NEIL1 excises psoralen-induced interstrand DNA cross-links in a three-stranded DNA structure. J Biol Chem (2009) 1.01
RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures. DNA Repair (Amst) (2010) 1.00
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome. J Biol Chem (2011) 0.98
Functions of disordered regions in mammalian early base excision repair proteins. Cell Mol Life Sci (2010) 0.98
Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends. J Biol Chem (2012) 0.97
Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage. Mutat Res (2012) 0.96
Variant base excision repair proteins: contributors to genomic instability. Semin Cancer Biol (2010) 0.96
Interplay between DNA repair and inflammation, and the link to cancer. Crit Rev Biochem Mol Biol (2014) 0.96
DNA glycosylases search for and remove oxidized DNA bases. Environ Mol Mutagen (2013) 0.94
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. DNA Repair (Amst) (2009) 0.93
Mutator phenotype of mammalian cells due to deficiency of NEIL1 DNA glycosylase, an oxidized base-specific repair enzyme. DNA Repair (Amst) (2008) 0.93
The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol (2013) 0.93
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2. DNA Repair (Amst) (2012) 0.92
Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction. J Biol Chem (2012) 0.92
Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2. J Biol Chem (2009) 0.92
Expression and purification of active mouse and human NEIL3 proteins. Protein Expr Purif (2012) 0.89
The current state of eukaryotic DNA base damage and repair. Nucleic Acids Res (2015) 0.89
Physical and functional interactions between uracil-DNA glycosylase and proliferating cell nuclear antigen from the euryarchaeon Pyrococcus furiosus. J Biol Chem (2008) 0.87
Oxidized base damage and single-strand break repair in mammalian genomes: role of disordered regions and posttranslational modifications in early enzymes. Prog Mol Biol Transl Sci (2012) 0.87
Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes. DNA Repair (Amst) (2013) 0.87
Human DNA Glycosylase NEIL1's Interactions with Downstream Repair Proteins Is Critical for Efficient Repair of Oxidized DNA Base Damage and Enhanced Cell Survival. Biomolecules (2012) 0.87
Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases. DNA Repair (Amst) (2013) 0.86
The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD. J Biol Chem (2015) 0.86
New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases. Biomolecules (2014) 0.86
Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging. Aging (Albany NY) (2012) 0.85
Insights into the glycosylase search for damage from single-molecule fluorescence microscopy. DNA Repair (Amst) (2014) 0.85
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest (2016) 0.85
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. J Biol Chem (2015) 0.84
Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases. DNA Repair (Amst) (2010) 0.84
New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins. Cell Mol Life Sci (2015) 0.83
ATP Depletion Via Mitochondrial F1F0 Complex by Lethal Factor is an Early Event in B. Anthracis-Induced Sudden Cell Death. J Cell Death (2009) 0.82
Formation and processing of DNA damage substrates for the hNEIL enzymes. Free Radic Biol Med (2016) 0.81
A chemical and kinetic perspective on base excision repair of DNA. Acc Chem Res (2014) 0.81
Base Excision Repair in the Mitochondria. J Cell Biochem (2015) 0.80
Induction of NEIL1 and NEIL2 DNA glycosylases in aniline-induced splenic toxicity. Toxicol Appl Pharmacol (2010) 0.80
X-ray repair cross complementing protein 1 in base excision repair. Int J Mol Sci (2012) 0.80
Human cells contain a factor that facilitates the DNA glycosylase-mediated excision of oxidized bases from occluded sites in nucleosomes. DNA Repair (Amst) (2017) 0.80
Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity. Mech Ageing Dev (2014) 0.79
Visualizing the Search for Radiation-damaged DNA Bases in Real Time. Radiat Phys Chem Oxf Engl 1993 (2016) 0.77
Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase. J Radiat Res (2014) 0.76
Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase. Nucleic Acids Res (2017) 0.75
Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase. PLoS One (2016) 0.75
Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repair. Nucleic Acids Res (2015) 0.75
Ubiquitylation-dependent regulation of NEIL1 by Mule and TRIM26 is required for the cellular DNA damage response. Nucleic Acids Res (2016) 0.75
Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target? Mech Ageing Dev (2016) 0.75
Base Excision Repair of N(6)-Deoxyadenosine Adducts of 1,3-Butadiene. Biochemistry (2016) 0.75
Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA Damage. J Nucleic Acids (2017) 0.75
Real-time imaging of DNA damage in yeast cells using ultra-short near-infrared pulsed laser irradiation. PLoS One (2014) 0.75
Biochemical characterization and novel inhibitor identification of Mycobacterium tuberculosis Endonuclease VIII 2 (Rv3297). Biochem Biophys Rep (2017) 0.75
Pre-Replicative Repair of Oxidized Bases Maintains Fidelity in Mammalian Genomes: The Cowcatcher Role of NEIL1 DNA Glycosylase. Genes (Basel) (2017) 0.75
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell (2011) 6.80
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res (2008) 3.48
AP endonuclease-independent DNA base excision repair in human cells. Mol Cell (2004) 3.37
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proc Natl Acad Sci U S A (2002) 3.33
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions. J Biol Chem (2002) 2.54
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. J Biol Chem (2003) 2.53
ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest (2005) 2.34
Two essential but distinct functions of the mammalian abasic endonuclease. Proc Natl Acad Sci U S A (2005) 2.26
Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer. Cancer Metastasis Rev (2009) 2.09
Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene. EMBO J (2003) 1.94
Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family. Int Immunopharmacol (2005) 1.92
RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes. Mol Cell Biol (2008) 1.91
Oxidative DNA damage repair in mammalian cells: a new perspective. DNA Repair (Amst) (2006) 1.85
Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein. Antioxid Redox Signal (2009) 1.81
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. J Biol Chem (2007) 1.78
The discovery of a new family of mammalian enzymes for repair of oxidatively damaged DNA, and its physiological implications. Carcinogenesis (2003) 1.77
Inactivation of hnRNP K by expanded intronic AUUCU repeat induces apoptosis via translocation of PKCdelta to mitochondria in spinocerebellar ataxia 10. PLoS Genet (2010) 1.76
De novo proteins from designed combinatorial libraries. Protein Sci (2004) 1.59
Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. Physiol Rev (2014) 1.57
STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen. Gastroenterology (2005) 1.56
Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage. Toxicology (2003) 1.52
Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo. Mol Cell Biol (2006) 1.48
TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway. Cell Signal (2007) 1.47
Mitochondrial dysfunction increases allergic airway inflammation. J Immunol (2009) 1.46
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. DNA Repair (Amst) (2006) 1.45
Long patch base excision repair in mammalian mitochondrial genomes. J Biol Chem (2008) 1.44
Choreography of oxidative damage repair in mammalian genomes. Free Radic Biol Med (2002) 1.43
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1. J Biol Chem (2007) 1.38
Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells. Nucleic Acids Res (2006) 1.36
Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein. J Biol Chem (2003) 1.34
Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress. J Biol Chem (2007) 1.32
Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells. Infect Immun (2007) 1.32
Retracted A Krüppel-associated box-zinc finger protein, NT2, represses cell-type-specific promoter activity of the alpha 2(XI) collagen gene. Mol Cell Biol (2002) 1.32
Macrophage infiltration predicts a poor prognosis for human ewing sarcoma. Am J Pathol (2011) 1.30
Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine. J Biol Chem (2012) 1.30
Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats. Mech Ageing Dev (2009) 1.29
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. J Biol Chem (2008) 1.27
Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1). Nucleic Acids Res (2005) 1.26
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. Proc Natl Acad Sci U S A (2003) 1.26
Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. Mol Cell Biol (2008) 1.24
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol (2009) 1.24
Functional analysis of the nuclear proteome of human A549 alveolar epithelial cells by HPLC-high resolution 2-D gel electrophoresis. Proteomics (2006) 1.23
Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells. Proteomics (2009) 1.23
Subpollen particles: carriers of allergenic proteins and oxidases. J Allergy Clin Immunol (2006) 1.23
Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein. DNA Repair (Amst) (2006) 1.23
Multifaceted resistance of gliomas to temozolomide. Clin Cancer Res (2002) 1.22
Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species. J Biol Chem (2005) 1.22
High fidelity and lesion bypass capability of human DNA polymerase delta. Biochimie (2009) 1.22
Exercise plays a preventive role against Alzheimer's disease. J Alzheimers Dis (2010) 1.22
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells. J Biol Chem (2010) 1.22
8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress. Free Radic Biol Med (2010) 1.20
Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA. Nucleic Acids Res (2009) 1.20
Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors. Clin Cancer Res (2012) 1.19
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem (2011) 1.18