Published in Epigenetics on January 01, 2012
Human metastable epiallele candidates link to common disorders. Epigenetics (2013) 1.07
Tissue-engineered kidney disease models. Adv Drug Deliv Rev (2013) 0.93
Regulatory network decoded from epigenomes of surface ectoderm-derived cell types. Nat Commun (2014) 0.88
Focal adhesion-chromatin linkage controls tumor cell resistance to radio- and chemotherapy. Chemother Res Pract (2012) 0.82
Effects of Shiga toxin type 2 on a bioengineered three-dimensional model of human renal tissue. Infect Immun (2014) 0.78
Breast Cancer beyond the Age of Mutation. Gerontology (2015) 0.78
Culture phases, cytotoxicity and protein expressions of agarose hydrogel induced Sp2/0, A549, MCF-7 cell line 3D cultures. Cytotechnology (2014) 0.77
Characterization of DNA Methylation in Circulating Tumor Cells. Genes (Basel) (2015) 0.75
TET2 Negatively Regulates Nestin Expression in Human Melanoma. Am J Pathol (2016) 0.75
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev (2006) 14.36
Putting tumours in context. Nat Rev Cancer (2001) 12.37
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet (2006) 10.47
Epigenetic stem cell signature in cancer. Nat Genet (2006) 9.62
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet (2007) 9.47
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol (2010) 6.67
Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell (2008) 5.88
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res (1995) 5.11
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet (2008) 5.08
miR-148 targets human DNMT3b protein coding region. RNA (2008) 4.56
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci U S A (2008) 4.20
QUMA: quantification tool for methylation analysis. Nucleic Acids Res (2008) 3.73
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes Dev (2008) 3.32
Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J Biol Chem (2000) 2.97
Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biochem (2007) 2.81
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines. Br J Cancer (2006) 2.74
Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J Cell Biochem (2007) 2.67
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res (1991) 2.67
MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol (2010) 2.63
Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]. J Pathol (2000) 2.61
E-cadherin expression in primary carcinomas of the breast and its distant metastases. Breast Cancer Res (2003) 2.61
Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proc Natl Acad Sci U S A (2008) 2.53
Targeting DNA methylation. Clin Cancer Res (2009) 2.45
Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition. Mol Cancer (2010) 2.31
Mechanisms of microRNA deregulation in human cancer. Cell Cycle (2008) 2.30
MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes. Hepatology (2010) 2.23
E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas. Clin Exp Metastasis (2008) 2.21
A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines. Mol Cancer (2004) 1.72
Altered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significance. J Gastrointest Surg (2010) 1.63
Mechanisms of inactivation of E-cadherin in breast cancer cell lines. Cancer Res (1998) 1.61
Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma. Lancet Oncol (2006) 1.61
Twisted epithelial-mesenchymal transition blocks senescence. Nat Cell Biol (2008) 1.42
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells. Mol Cancer Ther (2007) 1.42
CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer. BMC Cancer (2006) 1.41
The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis. Clin Chem (2010) 1.37
The role of cell adhesion molecules in cancer invasion and metastasis. Breast Cancer Res Treat (1993) 1.32
Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin. Clin Cancer Res (2004) 1.27
E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs. Cancer Res (2005) 1.26
Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression. Cancer Sci (2008) 1.20
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. Neoplasia (2008) 1.20
Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors. Carcinogenesis (2010) 1.17
Integrative network analysis reveals active microRNAs and their functions in gastric cancer. BMC Syst Biol (2011) 1.17
Expression of E-cadherin and catenins in invasive mammary carcinomas. Anticancer Res (1997) 1.10
Reduced E-cadherin expression is an indicator of unfavourable prognosis in oral squamous cell carcinoma. Oral Oncol (2005) 1.06
Three-dimensional tissue models of normal and diseased skin. Curr Protoc Cell Biol (2008) 1.05
Microenvironmental control of premalignant disease: the role of intercellular adhesion in the progression of squamous cell carcinoma. Semin Cancer Biol (2005) 1.00
Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients. Oral Oncol (2009) 0.98
E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J Invest Dermatol (2008) 0.94
Loss of intercellular adhesion activates a transition from low- to high-grade human squamous cell carcinoma. Int J Cancer (2006) 0.94
Laminin-1 induces E-cadherin expression in 3-dimensional cultured breast cancer cells by inhibiting DNA methyltransferase 1 and reversing promoter methylation status. FASEB J (2009) 0.92
Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene. PLoS One (2010) 0.91
Expression of integrins and E-cadherin in squamous cell carcinomas of the head and neck. APMIS (2004) 0.90
The extracellular matrix in oral squamous cell carcinoma: friend or foe? Head Neck (2006) 0.90
E-cadherin as an invasion suppressor. Ciba Found Symp (1995) 0.90
Basement membrane proteins promote progression of intraepithelial neoplasia in 3-dimensional models of human stratified epithelium. Int J Cancer (2004) 0.90
Establishment of an oral squamous cell carcinoma cell line with high invasive and p27 degradation activities from a lymph node metastasis. Oral Oncol (2003) 0.87
Differential expression of E-cadherin in metastatic lesions comparing to primary oral squamous cell carcinoma. J Oral Pathol Med (2006) 0.85
Expression of E-cadherin in cervical lymph nodes from primary oral squamous cell carcinoma patients. Arch Oral Biol (2007) 0.80
Induction of tumors in mice by genomic hypomethylation. Science (2003) 8.86
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Dev Cell (2003) 3.62
Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell (2005) 2.17
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proc Natl Acad Sci U S A (2005) 2.11
Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci U S A (2011) 2.01
Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair. Cell (2012) 1.98
Sclerosing odontogenic carcinoma with benign fibro-osseous lesion of the mandible: an extremely rare case report. Pathol Int (2010) 1.96
Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer. Cancer Res (2006) 1.93
Identification of the Staphylococcus aureus etd pathogenicity island which encodes a novel exfoliative toxin, ETD, and EDIN-B. Infect Immun (2002) 1.89
MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal. Differentiation (2007) 1.83
miR-22 represses cancer progression by inducing cellular senescence. J Cell Biol (2011) 1.78
Ultraviolet B irradiation induces expansion of intraepithelial tumor cells in a tissue model of early cancer progression. J Invest Dermatol (2003) 1.58
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat Biotechnol (2002) 1.57
Abrogation of E-cadherin-mediated adhesion induces tumor cell invasion in human skin-like organotypic culture. J Invest Dermatol (2003) 1.51
Neutralizing antibodies in patients with severe acute respiratory syndrome-associated coronavirus infection. J Infect Dis (2004) 1.50
Expression cloning of functional receptor used by SARS coronavirus. Biochem Biophys Res Commun (2004) 1.44
Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells. J Periodontol (2004) 1.44
The role of periostin in tissue remodeling across health and disease. Cell Mol Life Sci (2013) 1.42
A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. Biochem Biophys Res Commun (2006) 1.41
Analysis of microenvironmental factors contributing to basement membrane assembly and normalized epidermal phenotype. J Invest Dermatol (2003) 1.35
Suppression of intestinal neoplasia by deletion of Dnmt3b. Mol Cell Biol (2006) 1.35
An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study. J Oral Pathol Med (2007) 1.35
Identification of an antigenic determinant on the S2 domain of the severe acute respiratory syndrome coronavirus spike glycoprotein capable of inducing neutralizing antibodies. J Virol (2004) 1.32
Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin. Clin Cancer Res (2004) 1.27
E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs. Cancer Res (2005) 1.26
IFN-induced transmembrane protein 1 promotes invasion at early stage of head and neck cancer progression. Clin Cancer Res (2008) 1.24
Aurora-B regulates RNA methyltransferase NSUN2. Mol Biol Cell (2007) 1.22
Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis. Oncogene (2005) 1.22
Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation. Oncogene (2005) 1.21
Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression. Biochem Biophys Res Commun (2004) 1.20
Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation. Am J Pathol (2004) 1.17
The basement membrane microenvironment directs the normalization and survival of bioengineered human skin equivalents. Matrix Biol (2007) 1.13
Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin beta1 and CD63. Mol Cell Biol (2010) 1.08
Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer. PLoS One (2007) 1.07
Three-dimensional tissue models of normal and diseased skin. Curr Protoc Cell Biol (2008) 1.05
DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. J Cell Sci (2005) 1.05
Three-dimensional epithelial tissues generated from human embryonic stem cells. Tissue Eng Part A (2009) 1.04
MMP-10/stromelysin-2 promotes invasion of head and neck cancer. PLoS One (2011) 1.03
Caspase-2 and caspase-7 are involved in cytolethal distending toxin-induced apoptosis in Jurkat and MOLT-4 T-cell lines. Infect Immun (2004) 1.03
N-cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial-mesenchymal transition. Histol Histopathol (2011) 1.03
Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer. Virchows Arch (2007) 1.03
Denatured collagen modulates the phenotype of normal and wounded human skin equivalents. J Invest Dermatol (2008) 1.03
E-cadherin loss promotes the initiation of squamous cell carcinoma invasion through modulation of integrin-mediated adhesion. J Cell Sci (2006) 1.03
Soft tissue augmentation using silk gels: an in vitro and in vivo study. J Periodontol (2009) 1.02
The effect of experimental cartilage damage and impairment and restoration of synovial lubrication on friction in the temporomandibular joint. J Orofac Pain (2005) 1.02
Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells. Biochem Biophys Res Commun (2006) 1.02
Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells. PLoS One (2011) 1.01
Vascular endothelial growth factor plays an important autocrine/paracrine role in the progression of osteoarthritis. Histochem Cell Biol (2005) 1.01
Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B. Oral Oncol (2010) 1.01
RUNX3 has an oncogenic role in head and neck cancer. PLoS One (2009) 1.00
Microenvironmental control of premalignant disease: the role of intercellular adhesion in the progression of squamous cell carcinoma. Semin Cancer Biol (2005) 1.00
Dedifferentiated malignant myoepithelioma of the parotid gland. Pathol Int (2003) 1.00
Self-assembling peptide nanofiber scaffolds accelerate wound healing. PLoS One (2008) 0.99
RHAMM/ERK interaction induces proliferative activities of cementifying fibroma cells through a mechanism based on the CD44-EGFR. Lab Invest (2010) 0.98
In vitro fabrication of engineered human skin. Methods Mol Biol (2005) 0.98
Solitary fibrous tumor with malignant potential arising in sublingual gland. Pathol Int (2003) 0.97
Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis. J Biol Chem (2012) 0.95
Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer. Oncol Lett (2012) 0.94
Oncogenic role of RUNX3 in head and neck cancer. J Cell Biochem (2011) 0.94
E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J Invest Dermatol (2008) 0.94
Influence of additive hyaluronic acid on the lubricating ability in the temporomandibular joint. J Biomed Mater Res A (2004) 0.94
Loss of intercellular adhesion activates a transition from low- to high-grade human squamous cell carcinoma. Int J Cancer (2006) 0.94
Transfection of p27(Kip1) threonine residue 187 mutant type gene, which is not influenced by ubiquitin-mediated degradation, induces cell cycle arrest in oral squamous cell carcinoma cells. Oncology (2002) 0.93
Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas. Am J Pathol (2003) 0.92
Brain-derived neurotrophic factor stimulates bone/cementum-related protein gene expression in cementoblasts. J Biol Chem (2008) 0.92
Immortalization and characterization of human dental pulp cells with odontoblastic differentiation. Arch Oral Biol (2007) 0.92
Odontogenic tumors, WHO 2005: where do we go from here? Head Neck Pathol (2014) 0.91
Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells. J Virol (2004) 0.91
Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents. Stem Cell Res Ther (2011) 0.91
Three-dimensional human tissue models of wounded skin. Methods Mol Biol (2010) 0.90
Basement membrane proteins promote progression of intraepithelial neoplasia in 3-dimensional models of human stratified epithelium. Int J Cancer (2004) 0.90
Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers. DNA Cell Biol (2011) 0.90
Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas. Oncol Rep (2010) 0.89
MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility. Can J Anaesth (2007) 0.88
Characterization of the initial response of engineered human skin to sulfur mustard. Toxicol Sci (2005) 0.88
Atypical carcinoid (neuroendocrine carcinoma) of the gingiva: counterpart of a laryngeal tumor. Pathol Int (2004) 0.88