PubRank

D D Cunningham

Author PubWeight™ 101.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transport changes rapidly initiated by serum addition to "contact inhibited" 3T3 cells. Proc Natl Acad Sci U S A 1969 3.98
2 The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis. J Biol Chem 1982 3.41
3 Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Cell 1980 2.76
4 Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature 1989 2.17
5 No .NO from NO synthase. Proc Natl Acad Sci U S A 1996 2.14
6 Stimulation of division of density inhibited fibroblasts by glucocorticoids. Nature 1973 1.79
7 Selective radiolabeling of cell surface proteins to a high specific activity. Biochemistry 1987 1.74
8 A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands. Cell 1981 1.74
9 Thrombin active site regions required for fibroblast receptor binding and initiation of cell division. J Biol Chem 1980 1.56
10 Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system. J Biol Chem 1984 1.56
11 Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases. Proc Natl Acad Sci U S A 1981 1.53
12 Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J Neurosci 1997 1.45
13 Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci U S A 1988 1.40
14 Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J Neurosci 1995 1.37
15 Conditions which affect initiation of animal cell division by trypsin and thrombin. J Cell Physiol 1978 1.26
16 Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein. Science 1990 1.26
17 Cell surface action of thrombin is sufficient to initiate division of chick cells. Cell 1978 1.25
18 Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation. Nature 1979 1.23
19 Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J Neurosci 1995 1.22
20 Initiation of check cell division by trypsin action at the cell surface. Nature 1977 1.19
21 Epidermal growth factor immunoreactive material in the central nervous system: location and development. Science 1984 1.17
22 Dexamethasone modulates binding and action of epidermal growth factor in serum-free cell culture. Proc Natl Acad Sci U S A 1978 1.15
23 Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor. J Biol Chem 1990 1.14
24 Epidermal growth factor stimulates fluid phase endocytosis in human fibroblasts through a signal generated at the cell surface. J Cell Biochem 1982 1.12
25 Cells regulate their mitogenic response to thrombin through release of protease nexin. Nature 1982 1.10
26 Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem 1990 1.03
27 Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton. Proc Natl Acad Sci U S A 2000 1.02
28 Role of specific cell surface receptors in thrombin-stimulated cell division. Cell 1978 1.01
29 Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience 1992 0.99
30 Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions. J Biol Chem 1985 0.99
31 Purification of protease nexin II from human fibroblasts. J Biol Chem 1987 0.98
32 Modulation of thrombin-stimulated lipid responses in cultured fibroblasts. Evidence for two coupling mechanisms. Biochemistry 1987 0.94
33 Signaling pathways involved in thrombin-induced cell protection. J Biol Chem 1998 0.94
34 Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease. Proc Natl Acad Sci U S A 1989 0.93
35 Localization of protease nexin-1 on the fibroblast extracellular matrix. J Cell Physiol 1988 0.92
36 Serum-stimulated phosphate uptake and initiation of fibroblast proliferation. J Cell Physiol 1977 0.92
37 Photoaffinity labeling of a single receptor for alpha-thrombin on mouse embryo cells. J Biol Chem 1979 0.92
38 Human fibroblasts accelerate the inhibition of thrombin by protease nexin. Proc Natl Acad Sci U S A 1986 0.92
39 Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors. J Biol Chem 1993 0.92
40 Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases. Am J Pathol 1990 0.91
41 Injury-related factors and conditions down-regulate the thrombin receptor (PAR-1) in a human neuronal cell line. J Neurochem 1998 0.90
42 Thrombin-stimulated cell division involves proteolysis of its cell surface receptor. Nature 1979 0.90
43 A novel method for measuring cell surface-bound thrombin. Detection of iodination-induced changes in thrombin-binding affinity. J Biol Chem 1982 0.89
44 Epidermal growth factor carrier protein binds to cells via a complex with released carried protein nexin. Proc Natl Acad Sci U S A 1982 0.89
45 Photoaffinity labeling of specific alpha-thrombin binding sites on Chinese hamster lung cells. J Biol Chem 1983 0.89
46 Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. J Neurochem 1996 0.88
47 Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochem Biophys Res Commun 1991 0.87
48 Effects of EGF and thrombin on inositol-containing phospholipids of cultured fibroblasts: stimulation of phosphatidylinositol synthesis by thrombin but not EGF. J Cell Physiol 1985 0.87
49 Glycosaminoglycans on fibroblasts accelerate thrombin inhibition by protease nexin-1. Biochem J 1987 0.87
50 Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. J Cell Physiol 1990 0.87
51 Phosphate uptake and control of fibroblasts growth. J Cell Physiol 1977 0.87
52 Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor. J Biol Chem 1994 0.87
53 Protease nexins: cell-secreted proteins that mediate the binding, internalization, and degradation of regulatory serine proteases. J Cell Physiol 1983 0.86
54 Maximal concanavalin A-specific agglutinability without loss of density-dependent growth control. Proc Natl Acad Sci U S A 1973 0.86
55 Thrombin interactions with cultured fibroblasts: relationship to mitogenic stimulation. Ann N Y Acad Sci 1986 0.86
56 The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proc Natl Acad Sci U S A 1991 0.85
57 Changes in phospholipid turnover following growth of 3T3 mouse cells to confluency. J Biol Chem 1972 0.85
58 Amperometric enzyme electrodes for the determination of l-glutamate. Talanta 1991 0.85
59 Regulation of protease nexin-1 target protease specificity by collagen type IV. J Biol Chem 1994 0.85
60 A reevaluation of the response of human umbilical vein endothelial cells to certain growth factors. J Cell Physiol 1983 0.85
61 Binding of protease nexin-1 to the fibroblast surface alters its target proteinase specificity. J Biol Chem 1989 0.85
62 Structural features of steroids which initiate proliferation of density-inhibited 3T3 mouse fibroblasts. J Biol Chem 1974 0.85
63 Growth limitation of 3T3 mouse fibroblasts by available growth surface area and medium components. J Cell Physiol 1975 0.85
64 Nutrient uptake and control of animal cell proliferation. J Supramol Struct 1977 0.84
65 Direct linkage of thrombin to its cell surface receptors in different cell types. J Supramol Struct 1979 0.84
66 Dissociation of increased hexose transport from initiation of fibroblast proliferation. Nature 1974 0.83
67 Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J Neurochem 1995 0.83
68 Specific increase in pyrimidine deoxynucleoside transport at the time of deoxyribonucleic acid synthesis in 3T3 mouse cells. J Biol Chem 1973 0.83
69 Thrombin-mediated mitogenesis: the role of secreted protease nexin. J Cell Physiol 1982 0.83
70 Thrombin receptor signaling to cytoskeleton requires Hsp90. J Biol Chem 2001 0.83
71 Decreases in protease nexins in Alzheimer's disease brain. Neurobiol Aging 1996 0.83
72 Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts. J Biol Chem 1993 0.83
73 The relationship of disc position to zone-of-inhibition size in the disc-agar diffusion test. Methods Find Exp Clin Pharmacol 1983 0.83
74 Platelet protease nexin-2/amyloid beta-protein precursor. Possible pathologic and physiologic functions. Ann N Y Acad Sci 1991 0.82
75 Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Res 1993 0.81
76 Interactions of serine proteases with cultured fibroblasts. J Cell Biochem 1986 0.81
77 Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Res 1994 0.80
78 Purification of a proteinase inhibitor from bovine serum with C1-inhibitor activity. Biochim Biophys Acta 1987 0.80
79 Relationship of thrombin-stimulated arachidonic acid release and metabolism to mitogenesis and phosphatidylinositol synthesis. J Cell Physiol 1987 0.80
80 Purification of a form of protease nexin 1 that binds heparin with a low affinity. Biochemistry 1988 0.80
81 A simple two-step purification of protease nexin. Biochem J 1986 0.80
82 Glucocorticoid-mediated alteration in growth factor binding and action: analysis of the binding change. J Supramol Struct 1978 0.80
83 Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases. Biochemistry 1988 0.79
84 Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain. J Neurochem 1996 0.79
85 Inhibitors of urokinase and thrombin in cultured neural cells. J Neurochem 1991 0.79
86 Hexose uptake and control of fibroblast proliferation. J Cell Physiol 1977 0.79
87 Mechanisms of thrombin-stimulated cell division. J Supramol Struct 1979 0.79
88 Transmembrane action of thrombin initiates chick cell division. J Supramol Struct 1978 0.79
89 Functional and structural similarities between protease nexin I and C1 inhibitor. J Biol Chem 1988 0.79
90 Extraction of RNA polymerase from rat liver nuclei in a soluble form. Biochim Biophys Acta 1967 0.78
91 Protease nexin-1 complexes and inhibits T cell serine proteinase-1. Biochem Biophys Res Commun 1989 0.78
92 Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1. J Biol Chem 1997 0.78
93 Binding sites for elastase on cultured human fibroblasts that do not mediate internalization. J Cell Physiol 1987 0.77
94 Regulation and genetic control of brain amyloid. FESN Study Group. Brain Res Brain Res Rev 1991 0.77
95 Protease nexin-2/amyloid beta-protein precursor: a cerebral anticoagulant? J Clin Invest 1993 0.76
96 Transport inhibitors released by 3t3 mouse cells and their relation to growth control. J Cell Biol 1971 0.75
97 Identification of cell surface proteins sensitive to proteolysis by thrombin. Methods Enzymol 1987 0.75
98 Four Cases of Rhino-Scleroma. Ind Med Gaz 1889 0.75
99 The gamma subunit of 7 S nerve growth factor binds to cells via complexes formed with two cell-secreted nexins. J Biol Chem 1982 0.75
100 Effects of fibroblasts and endothelial cells on inactivation of target proteases by protease nexin-1, heparin cofactor II, and C1-inhibitor. J Cell Biochem 1988 0.75
101 Does hyaluronidase initiate DNA synthesis? J Cell Physiol 1973 0.75
102 On the Association of Several Distinct Species of Comma-Bacilli with Cases of Cholera in Calcutta. Ind Med Gaz 1890 0.75
103 Cleavage of cell surface proteins by thrombin. J Supramol Struct Cell Biochem 1981 0.75
104 The effects of cell-released protease nexin on the measurement of thrombin binding to mouse cells. Biochem Biophys Res Commun 1982 0.75
105 Glucocorticoids enhance the mitogenic action of insulin in serum-free cultures of chick embryo cells. J Cell Physiol 1979 0.75
106 Soluble RNA polymerase from rat liver nuclei. Biochim Biophys Acta 1969 0.75