Published in Proc Natl Acad Sci U S A on September 01, 1973
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Correlated suppression by 5-bromodeoxyuridine of tumorigenicity and plasminogen activator in mouse melanoma cells. Proc Natl Acad Sci U S A (1975) 1.08
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Interaction of the carbohydrate-binding protein concanavalin A with normal and transformed cells. Proc Natl Acad Sci U S A (1969) 5.39
Proteolytic enzymes initiating cell division and escape from contact inhibition of growth. Nature (1970) 3.84
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Surface-specific characteristics of a contact-inhibited cell line containing the SV40 viral genome. Proc Natl Acad Sci U S A (1969) 2.86
Stimulation of division of density inhibited fibroblasts by glucocorticoids. Nature (1973) 1.79
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Changes in phospholipid turnover following growth of 3T3 mouse cells to confluency. J Biol Chem (1972) 0.85
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Stimulation of division of density inhibited fibroblasts by glucocorticoids. Nature (1973) 1.79
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Thrombin active site regions required for fibroblast receptor binding and initiation of cell division. J Biol Chem (1980) 1.56
Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system. J Biol Chem (1984) 1.56
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Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J Neurosci (1997) 1.45
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Conditions which affect initiation of animal cell division by trypsin and thrombin. J Cell Physiol (1978) 1.26
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Cell surface action of thrombin is sufficient to initiate division of chick cells. Cell (1978) 1.25
Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation. Nature (1979) 1.23
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Initiation of check cell division by trypsin action at the cell surface. Nature (1977) 1.19
Epidermal growth factor immunoreactive material in the central nervous system: location and development. Science (1984) 1.17
Dexamethasone modulates binding and action of epidermal growth factor in serum-free cell culture. Proc Natl Acad Sci U S A (1978) 1.15
Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor. J Biol Chem (1990) 1.14
Epidermal growth factor stimulates fluid phase endocytosis in human fibroblasts through a signal generated at the cell surface. J Cell Biochem (1982) 1.12
Cells regulate their mitogenic response to thrombin through release of protease nexin. Nature (1982) 1.10
Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem (1990) 1.03
Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton. Proc Natl Acad Sci U S A (2000) 1.02
Role of specific cell surface receptors in thrombin-stimulated cell division. Cell (1978) 1.01
Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience (1992) 0.99
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Purification of protease nexin II from human fibroblasts. J Biol Chem (1987) 0.98
Modulation of thrombin-stimulated lipid responses in cultured fibroblasts. Evidence for two coupling mechanisms. Biochemistry (1987) 0.94
Signaling pathways involved in thrombin-induced cell protection. J Biol Chem (1998) 0.94
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease. Proc Natl Acad Sci U S A (1989) 0.93
Localization of protease nexin-1 on the fibroblast extracellular matrix. J Cell Physiol (1988) 0.92
Photoaffinity labeling of a single receptor for alpha-thrombin on mouse embryo cells. J Biol Chem (1979) 0.92
Serum-stimulated phosphate uptake and initiation of fibroblast proliferation. J Cell Physiol (1977) 0.92
Human fibroblasts accelerate the inhibition of thrombin by protease nexin. Proc Natl Acad Sci U S A (1986) 0.92
Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors. J Biol Chem (1993) 0.92
Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases. Am J Pathol (1990) 0.91
Injury-related factors and conditions down-regulate the thrombin receptor (PAR-1) in a human neuronal cell line. J Neurochem (1998) 0.90
Thrombin-stimulated cell division involves proteolysis of its cell surface receptor. Nature (1979) 0.90
A novel method for measuring cell surface-bound thrombin. Detection of iodination-induced changes in thrombin-binding affinity. J Biol Chem (1982) 0.89
Epidermal growth factor carrier protein binds to cells via a complex with released carried protein nexin. Proc Natl Acad Sci U S A (1982) 0.89
Photoaffinity labeling of specific alpha-thrombin binding sites on Chinese hamster lung cells. J Biol Chem (1983) 0.89
Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. J Neurochem (1996) 0.88
Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochem Biophys Res Commun (1991) 0.87
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Glycosaminoglycans on fibroblasts accelerate thrombin inhibition by protease nexin-1. Biochem J (1987) 0.87
Phosphate uptake and control of fibroblasts growth. J Cell Physiol (1977) 0.87
Effects of EGF and thrombin on inositol-containing phospholipids of cultured fibroblasts: stimulation of phosphatidylinositol synthesis by thrombin but not EGF. J Cell Physiol (1985) 0.87
Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. J Cell Physiol (1990) 0.87
Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor. J Biol Chem (1994) 0.87
Thrombin interactions with cultured fibroblasts: relationship to mitogenic stimulation. Ann N Y Acad Sci (1986) 0.86
Protease nexins: cell-secreted proteins that mediate the binding, internalization, and degradation of regulatory serine proteases. J Cell Physiol (1983) 0.86
Changes in phospholipid turnover following growth of 3T3 mouse cells to confluency. J Biol Chem (1972) 0.85
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proc Natl Acad Sci U S A (1991) 0.85
Binding of protease nexin-1 to the fibroblast surface alters its target proteinase specificity. J Biol Chem (1989) 0.85
Amperometric enzyme electrodes for the determination of l-glutamate. Talanta (1991) 0.85
A reevaluation of the response of human umbilical vein endothelial cells to certain growth factors. J Cell Physiol (1983) 0.85
Regulation of protease nexin-1 target protease specificity by collagen type IV. J Biol Chem (1994) 0.85
Structural features of steroids which initiate proliferation of density-inhibited 3T3 mouse fibroblasts. J Biol Chem (1974) 0.85
Growth limitation of 3T3 mouse fibroblasts by available growth surface area and medium components. J Cell Physiol (1975) 0.85
Nutrient uptake and control of animal cell proliferation. J Supramol Struct (1977) 0.84
Direct linkage of thrombin to its cell surface receptors in different cell types. J Supramol Struct (1979) 0.84
Dissociation of increased hexose transport from initiation of fibroblast proliferation. Nature (1974) 0.83
Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J Neurochem (1995) 0.83
Thrombin-mediated mitogenesis: the role of secreted protease nexin. J Cell Physiol (1982) 0.83
Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts. J Biol Chem (1993) 0.83
Thrombin receptor signaling to cytoskeleton requires Hsp90. J Biol Chem (2001) 0.83
Decreases in protease nexins in Alzheimer's disease brain. Neurobiol Aging (1996) 0.83
Specific increase in pyrimidine deoxynucleoside transport at the time of deoxyribonucleic acid synthesis in 3T3 mouse cells. J Biol Chem (1973) 0.83
The relationship of disc position to zone-of-inhibition size in the disc-agar diffusion test. Methods Find Exp Clin Pharmacol (1983) 0.83
Pathogenesis of renal hyperchloremic acidosis resulting from dietary potassium restriction in the dog: role of aldosterone. Am J Physiol (1980) 0.82
Pathophysiology of chronic renal tubular acidosis induced by administration of amiloride. J Lab Clin Med (1980) 0.82
Platelet protease nexin-2/amyloid beta-protein precursor. Possible pathologic and physiologic functions. Ann N Y Acad Sci (1991) 0.82
Interactions of serine proteases with cultured fibroblasts. J Cell Biochem (1986) 0.81
Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Res (1993) 0.81
A simple two-step purification of protease nexin. Biochem J (1986) 0.80
Relationship of thrombin-stimulated arachidonic acid release and metabolism to mitogenesis and phosphatidylinositol synthesis. J Cell Physiol (1987) 0.80
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Res (1994) 0.80
Glucocorticoid-mediated alteration in growth factor binding and action: analysis of the binding change. J Supramol Struct (1978) 0.80
Purification of a proteinase inhibitor from bovine serum with C1-inhibitor activity. Biochim Biophys Acta (1987) 0.80
Purification of a form of protease nexin 1 that binds heparin with a low affinity. Biochemistry (1988) 0.80
Transmembrane action of thrombin initiates chick cell division. J Supramol Struct (1978) 0.79
Hexose uptake and control of fibroblast proliferation. J Cell Physiol (1977) 0.79
Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain. J Neurochem (1996) 0.79
Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases. Biochemistry (1988) 0.79
Inhibitors of urokinase and thrombin in cultured neural cells. J Neurochem (1991) 0.79
Mechanisms of thrombin-stimulated cell division. J Supramol Struct (1979) 0.79
Functional and structural similarities between protease nexin I and C1 inhibitor. J Biol Chem (1988) 0.79
Protease nexin-1 complexes and inhibits T cell serine proteinase-1. Biochem Biophys Res Commun (1989) 0.78
Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1. J Biol Chem (1997) 0.78
Extraction of RNA polymerase from rat liver nuclei in a soluble form. Biochim Biophys Acta (1967) 0.78
Regulation and genetic control of brain amyloid. FESN Study Group. Brain Res Brain Res Rev (1991) 0.77