Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era.

PubWeight™: 1.18‹?› | Rank: Top 10%

🔗 View Article (PMC 3606053)

Published in AIDS on March 27, 2012

Authors

Alison Morris1, Matthew R Gingo, M Patricia George, Lorrie Lucht, Cathy Kessinger, Vikas Singh, Maria Hillenbrand, Michelle Busch, Deborah McMahon, Karen A Norris, Hunter C Champion, Mark T Gladwin, Yingze Zhang, Chad Steele, Frank C Sciurba

Author Affiliations

1: Department of Medicine, University of Alabama, Birmingham, USA. morrisa@upmc.edu

Associated clinical trials:

Adiposity and Airway Inflammation in HIV-Associated Airway Disease (SHOP) | NCT02975258

Pneumocystis in Pathogenesis of HIV-associated Emphysema (PACT) | NCT00869544

Articles citing this

HIV and noncommunicable cardiovascular and pulmonary diseases in low- and middle-income countries in the ART era: what we know and best directions for future research. J Acquir Immune Defic Syndr (2014) 1.22

Pathogenesis of HIV and the lung. Curr HIV/AIDS Rep (2013) 1.06

Enhanced pulmonary arteriopathy in simian immunodeficiency virus-infected macaques exposed to morphine. Am J Respir Crit Care Med (2012) 1.03

Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension. Am J Respir Cell Mol Biol (2012) 0.97

Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts. BMC Pulm Med (2014) 0.93

HIV infection is associated with diffusing capacity impairment in women. J Acquir Immune Defic Syndr (2013) 0.91

Endothelin-1 as a mediator and potential biomarker for interferon induced pulmonary toxicity. Pulm Circ (2012) 0.90

Serum (1→3)-β-D-glucan levels in HIV-infected individuals are associated with immunosuppression, inflammation, and cardiopulmonary function. J Acquir Immune Defic Syndr (2012) 0.88

Contributors to diffusion impairment in HIV-infected persons. Eur Respir J (2013) 0.85

Noninfectious pulmonary complications of human immunodeficiency virus infection. Am J Med Sci (2014) 0.84

Future directions: lung aging, inflammation, and human immunodeficiency virus. Clin Chest Med (2013) 0.83

Human immunodeficiency virus and pulmonary arterial hypertension. ISRN Cardiol (2013) 0.82

Obstructive Lung Diseases in HIV: A Clinical Review and Identification of Key Future Research Needs. Semin Respir Crit Care Med (2016) 0.82

Human immunodeficiency virus-associated pulmonary arterial hypertension. Clin Chest Med (2013) 0.79

Human immunodeficiency virus-1 transgene expression increases pulmonary vascular resistance and exacerbates hypoxia-induced pulmonary hypertension development. Pulm Circ (2013) 0.79

Injection drug use as a "second hit" in the pathogenesis of HIV-associated pulmonary hypertension. Am J Respir Crit Care Med (2012) 0.79

Thoracic diseases associated with HIV infection in the era of antiretroviral therapy: clinical and imaging findings. Radiographics (2014) 0.79

Maintaining lung health with longstanding HIV. Curr Opin Infect Dis (2016) 0.79

Novel relationships of markers of monocyte activation and endothelial dysfunction with pulmonary dysfunction in HIV-infected persons. AIDS (2016) 0.78

Factors related to NT-proBNP levels in HIV patients aged over 40 years. AIDS Res Ther (2015) 0.78

The complexity of HIV persistence and pathogenesis in the lung under antiretroviral therapy: challenges beyond AIDS. Viral Immunol (2014) 0.76

Elevated NT-pro-brain natriuretic peptide level is independently associated with all-cause mortality in HIV-infected women in the early and recent HAART eras in the Women's Interagency HIV Study cohort. PLoS One (2015) 0.76

Isolated right ventricular dysfunction in patients with human immunodeficiency virus. J Card Fail (2014) 0.75

Enterosalivary nitrate metabolism and the microbiome: intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health. Free Radic Biol Med (2016) 0.75

Infections in the immunosuppressed host. Ann Am Thorac Soc (2014) 0.75

Use of rosuvastatin in HIV-associated chronic obstructive pulmonary disease: A randomized pilot study. AIDS (2016) 0.75

Heart-lung interaction via infection. Ann Am Thorac Soc (2014) 0.75

Long-term pulmonary complications in perinatally HIV-infected youth. J Allergy Clin Immunol (2017) 0.75

Articles cited by this

A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med (1999) 82.86

Standardisation of spirometry. Eur Respir J (2005) 48.20

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2007) 47.86

Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med (1999) 29.97

Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr (1990) 25.24

Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med (2004) 10.51

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis (1999) 9.81

Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr (2002) 7.59

Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J (2005) 7.58

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood (2004) 7.09

Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. Circulation (1984) 5.60

Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med (1996) 5.53

Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 5.30

Report of the American Society of Echocardiography Committee on Nomenclature and Standards in Two-dimensional Echocardiography. Circulation (1980) 3.87

Systemic inflammation in patients with COPD and pulmonary hypertension. Chest (2006) 3.30

Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension. Circulation (2010) 3.02

HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era. Am J Respir Crit Care Med (2010) 3.00

Increased COPD among HIV-positive compared to HIV-negative veterans. Chest (2006) 2.93

Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers. Ann Intern Med (2000) 2.77

Role for interleukin-6 in COPD-related pulmonary hypertension. Chest (2009) 2.73

Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. AIDS (2003) 2.66

Primary pulmonary hypertension in HIV infection. Chest (1991) 2.40

Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med (2000) 2.36

Predictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1999) 2.29

Prognostic factors in COPD patients receiving long-term oxygen therapy. Importance of pulmonary artery pressure. Chest (1995) 2.22

Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension. AIDS (2008) 2.12

Risk of heart failure with human immunodeficiency virus in the absence of prior diagnosis of coronary heart disease. Arch Intern Med (2011) 2.08

Pulmonary hypertension in COPD. Eur Respir J (2008) 2.03

Prevalence of HIV-related pulmonary arterial hypertension in the current antiretroviral therapy era. Am J Respir Crit Care Med (2007) 2.03

Severe pulmonary hypertension and chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.91

Pulmonary arterial hypertension related to HIV infection: improved hemodynamics and survival associated with antiretroviral therapy. Clin Infect Dis (2004) 1.89

Pulmonary function abnormalities in HIV-infected patients during the current antiretroviral therapy era. Am J Respir Crit Care Med (2010) 1.81

Comparison of two methods of collecting induced sputum in asthmatic subjects. Eur Respir J (1996) 1.59

Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med (2001) 1.58

High Prevalence of Echocardiographic Abnormalities among HIV-infected Persons in the Era of Highly Active Antiretroviral Therapy. Clin Infect Dis (2010) 1.58

Cardiac manifestations of human immunodeficiency virus infection: a two-dimensional echocardiographic study. J Am Coll Cardiol (1989) 1.40

HIV-associated primary pulmonary hypertension. A case control study. Swiss HIV Cohort Study. Am J Respir Crit Care Med (1997) 1.35

Relationship between renal function and plasma brain natriuretic peptide in patients with heart failure. J Am Coll Cardiol (2006) 1.31

Impact of HIV infection on diastolic function and left ventricular mass. Circ Heart Fail (2009) 1.29

HIV-associated pulmonary arterial hypertension: survival and prognostic factors in the modern therapeutic era. AIDS (2010) 1.27

Standardized respiratory questionnaires: comparison of the old with the new. Am Rev Respir Dis (1979) 1.24

Immune activation in the pathogenesis of treated chronic HIV disease: a workshop summary. AIDS Res Hum Retroviruses (2011) 1.20

Frequency of Doppler measurable pulmonary artery pressures. J Am Soc Echocardiogr (1997) 1.16

Pulmonary hypertension in chronic obstructive pulmonary disease and interstitial lung diseases. Semin Respir Crit Care Med (2009) 1.14

The determinants of pulmonary diffusing capacity in a national sample of U.S. adults. Am J Respir Crit Care Med (1996) 1.13

Progression of chronic obstructive pulmonary disease: impact of inflammation, comorbidities and therapeutic intervention. Curr Med Res Opin (2009) 0.95

Soluble markers of inflammation are associated with Framingham scores in HIV-infected patients on suppressive antiretroviral therapy. J Infect (2011) 0.92

Correlation between peripheral blood T-cell profiles and clinical and inflammatory parameters in stable COPD. Allergol Int (2009) 0.88

Pulmonary hypertension in a stable community-based COPD population. Lung (2011) 0.87

Echocardiographic evidence of pulmonary hypertension is associated with increased 1-year mortality in patients admitted with chronic obstructive pulmonary disease. Lung (2011) 0.84

Treatment of acute chronic obstructive pulmonary disease exacerbation improves right ventricle function. Eur J Echocardiogr (2010) 0.80

Articles by these authors

Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med (2005) 17.61

The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med (2004) 17.08

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 16.54

Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol (2009) 12.05

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med (2003) 8.95

Azithromycin for prevention of exacerbations of COPD. N Engl J Med (2011) 8.66

Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med (2002) 7.59

The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov (2008) 7.58

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med (2005) 6.50

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. JAMA (2005) 6.49

Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol (2006) 6.36

Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA (2005) 6.14

Sickle-cell disease. Lancet (2010) 5.64

Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 5.31

Hemoglobin and the paracrine and endocrine functions of nitric oxide. N Engl J Med (2003) 4.98

Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med (2011) 4.75

Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes. Blood Rev (2006) 4.46

Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med (2010) 4.19

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. J Clin Invest (2005) 4.14

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood (2005) 3.98

Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med (2009) 3.96

Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Crit Care Med (2008) 3.94

Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion. Circulation (2011) 3.81

Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med (2006) 3.59

Predictive markers for AD in a multi-modality framework: an analysis of MCI progression in the ADNI population. Neuroimage (2010) 3.58

Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med (2014) 3.51

Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol (2005) 3.47

Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2012) 3.42

Outcomes of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the United States, 1998-2008. Am J Respir Crit Care Med (2011) 3.33

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer. J Exp Med (2007) 3.29

Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists. J Am Coll Cardiol (2009) 3.22

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest (2005) 3.22

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet (2013) 3.17

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. J Clin Invest (2005) 3.08

Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels. Circulation (2003) 3.01

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. J Exp Med (2006) 2.92

Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration. Circ Res (2007) 2.91

Endothelin axis is upregulated in human and rat right ventricular hypertrophy. Circ Res (2012) 2.83

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med (2008) 2.79

Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease. J Am Coll Cardiol (2007) 2.76

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood (2005) 2.76

Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis. Nat Chem Biol (2006) 2.75

Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin. J Clin Invest (2005) 2.75

Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol (2009) 2.74

Endothelial arginase II: a novel target for the treatment of atherosclerosis. Circ Res (2008) 2.70

Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension. Am J Respir Crit Care Med (2007) 2.68

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One (2008) 2.67

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation. Nat Immunol (2013) 2.60

Radiographic emphysema predicts low bone mineral density in a tobacco-exposed cohort. Am J Respir Crit Care Med (2010) 2.60

In-hospital complications associated with catheter ablation of atrial fibrillation in the United States between 2000 and 2010: analysis of 93 801 procedures. Circulation (2013) 2.56

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction. Proc Natl Acad Sci U S A (2004) 2.53

Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group. Ann Thorac Surg (2006) 2.53

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proc Natl Acad Sci U S A (2008) 2.53

High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury. Circulation (2008) 2.47

Spatially augmented LPboosting for AD classification with evaluations on the ADNI dataset. Neuroimage (2009) 2.47

Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. JAMA (2005) 2.47

Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation. Circulation (2007) 2.46

Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2009) 2.43

Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A (2004) 2.42

A network model to predict the risk of death in sickle cell disease. Blood (2007) 2.39

Effect of a retrograde-viewing device on adenoma detection rate during colonoscopy: the TERRACE study. Gastrointest Endosc (2010) 2.38

Knockdown of arginase I restores NO signaling in the vasculature of old rats. Hypertension (2005) 2.37

PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury. J Clin Invest (2005) 2.36

The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. J Biol Chem (2005) 2.34

Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin. Blood (2007) 2.31

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood (2007) 2.30

Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin. Nat Chem Biol (2007) 2.30

Nitrate and nitrite in biology, nutrition and therapeutics. Nat Chem Biol (2009) 2.29

Risk factors for progression of low-grade dysplasia in patients with Barrett's esophagus. Gastroenterology (2011) 2.27

L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial. JAMA (2006) 2.24

Patients with nondysplastic Barrett's esophagus have low risks for developing dysplasia or esophageal adenocarcinoma. Clin Gastroenterol Hepatol (2010) 2.24

An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease. Am J Respir Crit Care Med (2014) 2.23

Mortality increases after massive exchange transfusion with older stored blood in canines with experimental pneumonia. Blood (2012) 2.22

NO contest: nitrite versus S-nitroso-hemoglobin. Circ Res (2004) 2.21

Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis. JAMA (2013) 2.20

Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation. Haematologica (2009) 2.20

Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2008) 2.17

Improvements in symptom-limited exercise performance over 8 h with once-daily tiotropium in patients with COPD. Chest (2005) 2.15

Transcriptomic biomarkers for individual risk assessment in new-onset heart failure. Circulation (2008) 2.15

Nitrite as regulator of hypoxic signaling in mammalian physiology. Med Res Rev (2009) 2.15

Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction. Circulation (2008) 2.14

The relationship between pulmonary emphysema and kidney function in smokers. Chest (2012) 2.13

Half-Integrality based Algorithms for Cosegmentation of Images. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit (2009) 2.11

Automated lung segmentation in X-ray computed tomography: development and evaluation of a heuristic threshold-based scheme. Acad Radiol (2003) 2.10

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator. Nat Med (2004) 2.09

Erythrocytes are the major intravascular storage sites of nitrite in human blood. Blood (2005) 2.08

Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart. J Am Coll Cardiol (2007) 2.07

Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease. Blood (2004) 2.06

Measurement of circulating nitrite and S-nitrosothiols by reductive chemiluminescence. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 2.06

Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions. Am J Hematol (2009) 2.05

Interruption of antiretroviral treatment in HIV-infected patients with preserved immune function is associated with a low rate of clinical progression: a prospective study by AIDS Clinical Trials Group 5170. J Infect Dis (2007) 2.05

Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization. Am J Respir Crit Care Med (2004) 2.05

Clinical differences between idiopathic and scleroderma-related pulmonary hypertension. Arthritis Rheum (2006) 2.04