PubRank

Adiposity and Airway Inflammation in HIV-Associated Airway Disease (SHOP)

Clinical Trial ID NCT02975258

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🔗 Visit the ClinicalTrials.gov page for NCT02975258

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003 41.22
2 Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993 25.54
3 Oxidants, oxidative stress and the biology of ageing. Nature 2000 23.21
4 Interpretative strategies for lung function tests. Eur Respir J 2005 21.50
5 Inflammation and insulin resistance. J Clin Invest 2006 18.76
6 Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 1995 17.42
7 Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 2000 9.44
8 Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 2003 7.47
9 Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2009 7.17
10 T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 2009 7.11
11 Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998 7.05
12 Inflammatory links between obesity and metabolic disease. J Clin Invest 2011 6.73
13 Odds ratios for mediation analysis for a dichotomous outcome. Am J Epidemiol 2010 6.03
14 HIV infection and the risk of acute myocardial infarction. JAMA Intern Med 2013 5.90
15 Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 2008 5.80
16 Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006 5.50
17 Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996 4.98
18 Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 2012 4.85
19 Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999 4.75
20 Trends in asthma prevalence, health care use, and mortality in the United States, 2001-2010. NCHS Data Brief 2012 4.00
21 The end of AIDS: HIV infection as a chronic disease. Lancet 2013 3.96
22 Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007 3.95
23 Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008 3.70
24 Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 1998 3.25
25 Airway remodeling in asthma. J Clin Invest 1999 3.19
26 The prediction of small airway dimensions using computed tomography. Am J Respir Crit Care Med 2004 3.02
27 Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem 1997 3.02
28 HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era. Am J Respir Crit Care Med 2010 3.00
29 Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J Biol Chem 1993 2.94
30 Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects. Arterioscler Thromb Vasc Biol 2008 2.82
31 Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 2004 2.80
32 Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. Circulation 1999 2.77
33 Definition and classification of chronic bronchitis for clinical and epidemiological purposes. A report to the Medical Research Council by their Committee on the Aetiology of Chronic Bronchitis. Lancet 1965 2.74
34 Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation. J Allergy Clin Immunol 2011 2.53
35 Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy. J Infect Dis 2011 2.44
36 Influence of body mass index on the response to asthma controller agents. Eur Respir J 2006 2.41
37 Retracted Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. Am J Respir Crit Care Med 2012 2.39
38 Effect of leptin on allergic airway responses in mice. J Allergy Clin Immunol 2005 2.08
39 Current asthma prevalence - United States, 2006-2008. MMWR Surveill Summ 2011 2.01
40 Induced sputum cell counts in healthy adults. Am J Respir Crit Care Med 2000 1.93
41 The changing spectrum of pulmonary disease in patients with HIV infection on antiretroviral therapy. AIDS 2006 1.88
42 An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med 2012 1.85
43 HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation. Clin Infect Dis 2012 1.83
44 Pulmonary function abnormalities in HIV-infected patients during the current antiretroviral therapy era. Am J Respir Crit Care Med 2010 1.81
45 Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology. Chest 2008 1.80
46 Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med 2005 1.72
47 Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. Am J Respir Crit Care Med 2014 1.69
48 The DDAH/ADMA/NOS pathway. Atheroscler Suppl 2003 1.68
49 Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Anal Biochem 2002 1.64
50 Obesity and asthma: an association modified by age of asthma onset. J Allergy Clin Immunol 2011 1.64
51 The risk of incident coronary heart disease among veterans with and without HIV and hepatitis C. Circ Cardiovasc Qual Outcomes 2011 1.62
52 Effect of rosiglitazone on peroxisome proliferator-activated receptor gamma gene expression in human adipose tissue is limited by antiretroviral drug-induced mitochondrial dysfunction. J Infect Dis 2008 1.60
53 Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma. Am J Pathol 2004 1.58
54 Cluster analysis of obesity and asthma phenotypes. PLoS One 2012 1.56
55 Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction. J Allergy Clin Immunol 2009 1.52
56 Differences in airway remodeling between subjects with severe and moderate asthma. J Allergy Clin Immunol 2005 1.52
57 Low serum adiponectin predicts future risk for asthma in women. Am J Respir Crit Care Med 2012 1.52
58 Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis. J Cardiovasc Pharmacol 1992 1.51
59 Airway dimensions and pulmonary function in chronic obstructive pulmonary disease and bronchial asthma. Respirology 2012 1.48
60 Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease. Am J Respir Crit Care Med 1998 1.47
61 Body mass index and phenotype in subjects with mild-to-moderate persistent asthma. J Allergy Clin Immunol 2009 1.43
62 Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes. J Allergy Clin Immunol 2006 1.43
63 Induced sputum cellularity. Reference values and distribution in normal volunteers. Am J Respir Crit Care Med 2000 1.40
64 Obesity, airway hyperresponsiveness, and inflammation. J Appl Physiol (1985) 2009 1.34
65 Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics. Respir Res 2007 1.33
66 Bronchial measurements in patients with asthma: comparison of quantitative thin-section CT findings with those in healthy subjects and correlation with pathologic findings. Radiology 2009 1.32
67 Multimorbidity patterns in HIV-infected patients: the role of obesity in chronic disease clustering. J Acquir Immune Defic Syndr 2012 1.30
68 Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy. AIDS 2003 1.29
69 Association between asthma and serum adiponectin concentration in women. Thorax 2008 1.27
70 Body size phenotypes and inflammation in the Women's Health Initiative Observational Study. Obesity (Silver Spring) 2011 1.27
71 Asymmetric dimethylarginine is increased in asthma. Am J Respir Crit Care Med 2011 1.25
72 Validation of a new questionnaire on asthma, allergic rhinitis, and conjunctivitis in young adults. Allergy 2001 1.25
73 Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era. AIDS 2012 1.18
74 Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity. J Allergy Clin Immunol 2012 1.17
75 Prevalence of bronchial hyperresponsiveness among HIV-infected men. Am J Respir Crit Care Med 2001 1.16
76 Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals. PLoS One 2011 1.15
77 The role of oxidized low-density lipoproteins in atherosclerosis: the myths and the facts. Mediators Inflamm 2013 1.15
78 Asthma diagnosis and airway bronchodilator response in HIV-infected patients. J Allergy Clin Immunol 2011 1.13
79 Lessons learned from the first wave of aging with HIV. AIDS 2012 1.13
80 Optimal threshold in CT quantification of emphysema. Eur Radiol 2012 1.12
81 Central obesity is associated with nonatopic but not atopic asthma in a representative population sample. J Allergy Clin Immunol 2006 1.09
82 Plasma asymmetric dimethylarginine concentrations are elevated in obese insulin-resistant women and fall with weight loss. J Clin Endocrinol Metab 2006 1.08
83 Measuring health-related quality of life in adults during an acute asthma exacerbation. Chest 2004 1.06
84 HIV therapy, metabolic syndrome, and cardiovascular risk. Curr Atheroscler Rep 2008 1.06
85 The impact of HAART on the respiratory complications of HIV infection: longitudinal trends in the MACS and WIHS cohorts. PLoS One 2013 1.06
86 HIV-associated lung infections and complications in the era of combination antiretroviral therapy. Proc Am Thorac Soc 2011 1.05
87 Endothelial function is impaired in HIV-infected patients with lipodystrophy. Antivir Ther 2010 1.04
88 Increased oxidative stress and altered levels of antioxidants in chronic obstructive pulmonary disease. Inflammation 2005 1.04
89 Regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase. Circ Res 2003 1.02
90 Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. J Clin Endocrinol Metab 2003 1.02
91 Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma. Am J Physiol Lung Cell Mol Physiol 2010 0.99
92 Automated detection and quantitative assessment of pulmonary airways depicted on CT images. Med Phys 2007 0.99
93 Airway inflammation and remodeling in asthma. Lessons from interleukin 11 and interleukin 13 transgenic mice. Am J Respir Crit Care Med 2001 0.98
94 Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men. Int J Cardiol 2010 0.97
95 Plasma concentrations of the cardiovascular risk factor asymmetric dimethylarginine (ADMA) are increased in patients with HIV-1 infection and correlate with immune activation markers. Pharmacol Res 2009 0.96
96 Elevated concentration of asymmetric dimethylarginine (ADMA) in individuals with metabolic syndrome. Nitric Oxide 2011 0.96
97 Safety of investigative bronchoscopy in the Severe Asthma Research Program. J Allergy Clin Immunol 2011 0.95
98 Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial. AIDS Res Hum Retroviruses 2013 0.93
99 Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts. BMC Pulm Med 2014 0.93
100 New NHLBI guidelines for the diagnosis and management of asthma. National Heart, Lung and Blood Institute. Lippincott Health Promot Lett 1997 0.92
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