Published in Antioxid Redox Signal on July 01, 2012
The role of mitochondrial dysfunction in sepsis-induced multi-organ failure. Virulence (2013) 1.29
H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing. Am J Physiol Regul Integr Comp Physiol (2013) 1.19
Oxygen deficit and H2S in hemorrhagic shock in rats. Crit Care (2012) 1.13
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects. Br J Pharmacol (2014) 1.10
Signaling molecules: hydrogen sulfide and polysulfide. Antioxid Redox Signal (2014) 1.07
Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure. Antioxid Redox Signal (2013) 1.00
Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis. Proc Natl Acad Sci U S A (2014) 0.99
Inhaled hydrogen sulfide protects against lipopolysaccharide-induced acute lung injury in mice. Med Gas Res (2012) 0.96
A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal death. J Biol Chem (2012) 0.95
Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism. PLoS One (2013) 0.90
Treatment with exogenous hydrogen sulfide attenuates hyperoxia-induced acute lung injury in mice. Eur J Appl Physiol (2013) 0.90
Endogenous H2S in hemorrhagic shock: innocent bystander or central player? Crit Care (2012) 0.89
The role of H2S bioavailability in endothelial dysfunction. Trends Pharmacol Sci (2015) 0.88
Sodium thiosulfate attenuates acute lung injury in mice. Anesthesiology (2014) 0.88
Urinary sulfur metabolites associate with a favorable cardiovascular risk profile and survival benefit in renal transplant recipients. J Am Soc Nephrol (2014) 0.87
Protective effect of endogenous hydrogen sulfide against oxidative stress in gastric ischemia-reperfusion injury. Exp Ther Med (2012) 0.87
H2S during circulatory shock: some unresolved questions. Nitric Oxide (2014) 0.86
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats. Br J Pharmacol (2015) 0.85
Thiosulfate Mediates Cytoprotective Effects of Hydrogen Sulfide Against Neuronal Ischemia. J Am Heart Assoc (2015) 0.84
Mitochondrial dysfunction remodels one-carbon metabolism in human cells. Elife (2016) 0.84
Hydrogen sulfide reduces kidney injury due to urinary-derived sepsis by inhibiting NF-κB expression, decreasing TNF-α levels and increasing IL-10 levels. Exp Ther Med (2014) 0.83
Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling. Int J Mol Med (2015) 0.81
A gas chromatography-mass spectrometry based study on urine metabolomics in rats chronically poisoned with hydrogen sulfide. Biomed Res Int (2015) 0.80
Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis. PLoS One (2016) 0.79
Protective effects of hydrogen sulfide inhalation on oxidative stress in rats with cotton smoke inhalation-induced lung injury. Exp Ther Med (2015) 0.77
The summer of hydrogen sulfide: highlights from two international conferences. Med Gas Res (2013) 0.77
In vivo study of the effects of exogenous hydrogen sulfide on lung mitochondria in acute lung injury in rats. BMC Anesthesiol (2014) 0.77
Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases. J Neuroinflammation (2016) 0.76
Sodium Hydrosulphide alleviates remote lung injury following limb traumatic injury in rats. PLoS One (2013) 0.75
Is pharmacological, H₂S-induced 'suspended animation' feasible in the ICU? Crit Care (2014) 0.75
S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway. Redox Biol (2016) 0.75
Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase. Int J Mol Med (2016) 0.75
Hydrosulfide attenuates acute myocardial ischemic injury through the glycogen synthase kinase-3β/β-catenin signaling pathway. Int J Mol Med (2016) 0.75
Farnesyltransferase inhibitor, tipifarnib, prevents galactosamine/lipopolysaccharide-induced acute liver failure. Shock (2014) 0.75
Inhaled hydrogen sulfide prevents neuropathic pain after peripheral nerve injury in mice. Nitric Oxide (2014) 0.75
International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H2S Levels: H2S Donors and H2S Biosynthesis Inhibitors. Pharmacol Rev (2017) 0.75
Significance of hydrogen sulfide in sepsis-induced myocardial injury in rats. Exp Ther Med (2017) 0.75
Sodium thiosulphate attenuates brain inflammation induced by systemic lipopolysaccharide administration in C57BL/6J mice. Inflammopharmacology (2017) 0.75
Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat. Biochem J (1982) 3.76
Redox biochemistry of hydrogen sulfide. J Biol Chem (2010) 3.64
3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain. Antioxid Redox Signal (2009) 3.44
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J (2005) 3.23
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide. Circulation (2008) 2.74
Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J (2004) 2.59
Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J (2008) 2.33
Immunopathologic alterations in murine models of sepsis of increasing severity. Infect Immun (1999) 2.13
Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues. Anal Biochem (2005) 1.97
Is hydrogen sulfide a circulating "gasotransmitter" in vertebrate blood? Biochim Biophys Acta (2009) 1.83
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function. Proc Natl Acad Sci U S A (2011) 1.82
Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative. Free Radic Biol Med (2006) 1.81
A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood. Br J Pharmacol (2010) 1.75
Measurement of plasma hydrogen sulfide in vivo and in vitro. Free Radic Biol Med (2011) 1.74
The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxid Redox Signal (2010) 1.72
GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat. Free Radic Biol Med (2009) 1.63
Intrahepatic synthesis of tumor necrosis factor-alpha related to cardiac surgery is inhibited by interleukin-10 via the Janus kinase (Jak)/signal transducers and activator of transcription (STAT) pathway. Crit Care Med (2003) 1.56
Effects of mild induced hypothermia during experimental sepsis. Crit Care Med (2006) 1.53
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide. Biochem J (2011) 1.38
Sodium thiosulfate: new hope for the treatment of calciphylaxis. Semin Dial (2010) 1.34
Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse. Anesthesiology (2008) 1.30
Bacterial peptidoglycan-associated lipoprotein is released into the bloodstream in gram-negative sepsis and causes inflammation and death in mice. J Biol Chem (2002) 1.23
Hypothermia and sepsis. Front Biosci (2006) 1.21
Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB. Am J Physiol Lung Cell Mol Physiol (2007) 1.19
Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis. J Immunol (2008) 1.14
Mast cells are necessary for the hypothermic response to LPS-induced sepsis. Am J Physiol Regul Integr Comp Physiol (2008) 1.07
Correction of perioperative hypothermia decreases experimental sepsis mortality by modulating the inflammatory response. Crit Care Med (2005) 1.06
From O2 to H2S: a landscape view of gas biology. Keio J Med (2002) 0.97
Isolation and partial purification of mitochondrial and cytosolic rhodanese from liver of normal and p-dimethylaminoazobenzene treated mice. Int J Biochem Cell Biol (1995) 0.82
Altered glucose metabolism and preserved energy charge and neuronal structures in the brain of mouse intermittently exposed to hypoxia. J Chem Neuroanat (2011) 0.81
Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci U S A (2007) 5.36
3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain. Antioxid Redox Signal (2009) 3.44
Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. J Biochem (2009) 3.25
Hydrogen sulfide protects neurons from oxidative stress. FASEB J (2004) 3.22
Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J (2004) 2.59
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia. Circ Res (2007) 2.43
Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxid Redox Signal (2010) 2.19
Extensive HLA class I allele promiscuity among viral CTL epitopes. Eur J Immunol (2007) 2.10
Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury. Eur Heart J (2006) 1.98
A source of hydrogen sulfide and a mechanism of its release in the brain. Antioxid Redox Signal (2009) 1.98
Toll-like receptor 2 plays a critical role in cardiac dysfunction during polymicrobial sepsis. Crit Care Med (2010) 1.84
Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury. Anesthesiology (2008) 1.77
Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. Circulation (2009) 1.75
Protective and Detrimental Effects of Sodium Sulfide and Hydrogen Sulfide in Murine Ventilator-induced Lung Injury. Anesthesiology (2011) 1.74
Hydrogen sulfide protects HT22 neuronal cells from oxidative stress. Antioxid Redox Signal (2006) 1.73
Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH. Proc Natl Acad Sci U S A (2013) 1.68
Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. Gastroenterology (2006) 1.66
Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. JACC Cardiovasc Imaging (2012) 1.66
Differential gene profiling in acute lung injury identifies injury-specific gene expression. Crit Care Med (2008) 1.65
BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol (2004) 1.64
Protective effects of nitric oxide synthase 3 and soluble guanylate cyclase on the outcome of cardiac arrest and cardiopulmonary resuscitation in mice. Crit Care Med (2009) 1.63
Increased leakage of sarcoplasmic reticulum Ca2+ contributes to abnormal myocyte Ca2+ handling and shortening in sepsis. Crit Care Med (2005) 1.63
Polysulfides are possible H2S-derived signaling molecules in rat brain. FASEB J (2013) 1.62
Inhaled nitric oxide enables artificial blood transfusion without hypertension. Circulation (2008) 1.60
Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol (2006) 1.57
CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control. PLoS One (2012) 1.48
Spontaneous transformation of cultured mouse bone marrow-derived stromal cells. Cancer Res (2006) 1.48
Therapeutic targeting of the stem cell niche in experimental hindlimb ischemia. Nat Clin Pract Cardiovasc Med (2008) 1.47
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44
Hydrogen sulfide induces calcium waves in astrocytes. FASEB J (2004) 1.43
Development of a highly selective fluorescence probe for hydrogen sulfide. J Am Chem Soc (2011) 1.43
Gender-specific hypertension and responsiveness to nitric oxide in sGCalpha1 knockout mice. Cardiovasc Res (2008) 1.39
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide. Biochem J (2011) 1.38
Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS. FASEB J (2005) 1.36
L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter. Diabetes (2006) 1.36
A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells. Nat Commun (2013) 1.35
Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin. Circulation (2007) 1.35
Atrial fibrillation in patients with Brugada syndrome relationships of gene mutation, electrophysiology, and clinical backgrounds. J Am Coll Cardiol (2008) 1.33
Brain hydrogen sulfide is severely decreased in Alzheimer's disease. Biochem Biophys Res Commun (2002) 1.32
Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse. Anesthesiology (2008) 1.30
Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia. J Biol Chem (2004) 1.28
Retracted Hydrogen sulfide is produced in response to neuronal excitation. J Neurosci (2002) 1.25
Inhaled NO as a therapeutic agent. Cardiovasc Res (2007) 1.23
Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia. Cardiovasc Res (2005) 1.22
sGC(alpha)1(beta)1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models. Am J Physiol Heart Circ Physiol (2009) 1.21
Cystathionine beta-synthase is enriched in the brains of Down's patients. Biochem Biophys Res Commun (2005) 1.20
Increased sequence diversity coverage improves detection of HIV-specific T cell responses. J Immunol (2007) 1.17
Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs. Circulation (2004) 1.17
Hydrogen sulfide protects the retina from light-induced degeneration by the modulation of Ca2+ influx. J Biol Chem (2011) 1.16
MOCA induces membrane spreading by activating Rac1. J Biol Chem (2004) 1.16
Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease. Antioxid Redox Signal (2011) 1.15
Recovery profiles from dexmedetomidine as a general anesthetic adjuvant in patients undergoing lower abdominal surgery. Anesth Analg (2008) 1.14
Quantitative assessment of regional myocardial function in mice by tissue Doppler imaging: comparison with hemodynamics and sonomicrometry. Circulation (2005) 1.14
5-Lipoxygenase deficiency prevents respiratory failure during ventilator-induced lung injury. Am J Respir Crit Care Med (2005) 1.13
Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese. Genomics (2009) 1.12
Hemodynamic forces regulate mural macrophage infiltration in experimental aortic aneurysms. Exp Mol Pathol (2004) 1.11
In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: validation and application in nitric oxide synthase 3 deficient mice. Circulation (2007) 1.10
Polysulfide exerts a protective effect against cytotoxicity caused by t-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells. FEBS Lett (2013) 1.09
Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress. Proc Natl Acad Sci U S A (2005) 1.07
Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex. Proc Natl Acad Sci U S A (2010) 1.07
Cardiomyocyte-restricted restoration of nitric oxide synthase 3 attenuates left ventricular remodeling after chronic pressure overload. Am J Physiol Heart Circ Physiol (2007) 1.07
A novel enhancing mechanism for hydrogen sulfide-producing activity of cystathionine beta-synthase. J Biol Chem (2002) 1.06
Nos3 protects against systemic inflammation and myocardial dysfunction in murine polymicrobial sepsis. Shock (2010) 1.05
Clinical outcome and complications of temporary inferior vena cava filter placement. J Vasc Surg (2006) 1.04
Chronic treatment with nitric oxide-releasing aspirin reduces plasma low-density lipoprotein oxidation and oxidative stress, arterial oxidation-specific epitopes, and atherogenesis in hypercholesterolemic mice. Proc Natl Acad Sci U S A (2002) 1.04
Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population. Hum Mutat (2004) 1.03
GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring) (2008) 1.01
Cystathionine γ-lyase deficiency protects mice from galactosamine/lipopolysaccharide-induced acute liver failure. Antioxid Redox Signal (2013) 1.00
Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose. FEBS Lett (2008) 1.00
Inhaled nitric oxide improves outcomes after successful cardiopulmonary resuscitation in mice. Circulation (2011) 0.99
Novel parathyroid hormone (PTH) antagonists that bind to the juxtamembrane portion of the PTH/PTH-related protein receptor. J Biol Chem (2004) 0.99
Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia. Circulation (2007) 0.99
The potential dual effects of anesthetic isoflurane on Aβ-induced apoptosis. Curr Alzheimer Res (2011) 0.98
Spontaneous mesenteric hemorrhage associated with Ehlers-Danlos syndrome. J Gastrointest Surg (2006) 0.97
A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal death. J Biol Chem (2012) 0.95
Continuous periaortic infusion improves doxycycline efficacy in experimental aortic aneurysms. J Vasc Surg (2004) 0.93
Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor. J Biol Chem (2006) 0.93
Determination of oxidized and reduced nicotinamide adenine dinucleotide in cell monolayers using a single extraction procedure and a spectrophotometric assay. Anal Biochem (2005) 0.92
Autotaxin expression is enhanced in frontal cortex of Alzheimer-type dementia patients. Neurosci Lett (2006) 0.91
Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice. Proc Natl Acad Sci U S A (2006) 0.91
Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice. Anesthesiology (2002) 0.91
Elevated levels of oxidative DNA damage in serum and myocardium of patients with heart failure. Circ J (2006) 0.90
Amino-terminal parathyroid hormone fragment analogs containing alpha,alpha-di-alkyl amino acids at positions 1 and 3. J Bone Miner Res (2004) 0.90
Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS pathways. J Cardiovasc Pharmacol (2007) 0.90
Functional impairment of hematopoietic progenitor cells in patients with coronary heart disease. Eur J Haematol (2007) 0.89
Sodium sulfide prevents water diffusion abnormality in the brain and improves long term outcome after cardiac arrest in mice. Resuscitation (2012) 0.89
Antioxidants increase number of progenitor endothelial cells through multiple gene expression pathways. Free Radic Res (2008) 0.89
Inhibition of phosphodiesterase 1 augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs with acute pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2005) 0.89
Surgical result of critical limb ischemia due to tibial arterial occlusion in patients with systemic scleroderma. J Vasc Surg (2009) 0.88
Sodium thiosulfate attenuates acute lung injury in mice. Anesthesiology (2014) 0.88
Myocardial alterations in senescent mice and effect of exercise training: a strain rate imaging study. Circ Cardiovasc Imaging (2008) 0.88