Published in Aging Cell on January 19, 2012
Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol (2014) 2.40
Pluripotent stem cells escape from senescence-associated DNA methylation changes. Genome Res (2012) 1.32
Donor age of human platelet lysate affects proliferation and differentiation of mesenchymal stem cells. PLoS One (2012) 1.18
Hematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture. Sci Rep (2013) 1.04
Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells. Stem Cell Reports (2014) 1.01
Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites. Clin Epigenetics (2015) 0.91
Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy. Int J Mol Sci (2016) 0.91
DNA Methylation Changes during In Vitro Propagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability? Stem Cells Int (2013) 0.90
Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease? Semin Nephrol (2013) 0.90
DNA-methylation profiling of fetal tissues reveals marked epigenetic differences between chorionic and amniotic samples. PLoS One (2012) 0.88
Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes. BMC Res Notes (2014) 0.85
Epigenetics and aging. Sci Adv (2016) 0.84
Implications of long-term culture for mesenchymal stem cells: genetic defects or epigenetic regulation? Stem Cell Res Ther (2012) 0.83
Epigenetic biomarker to support classification into pluripotent and non-pluripotent cells. Sci Rep (2015) 0.82
IGF2/H19 hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome. Clin Epigenetics (2012) 0.81
Cellular Senescence as the Causal Nexus of Aging. Front Genet (2016) 0.80
TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages. PLoS One (2013) 0.79
The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation. Nucleic Acids Res (2016) 0.76
Senescence-associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells. Aging Cell (2016) 0.75
In silico approaches and the role of ontologies in aging research. Rejuvenation Res (2013) 0.75
Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level. Springerplus (2016) 0.75
Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias. Neoplasia (2014) 0.75
Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range. Stem Cells Int (2017) 0.75
Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements. Stem Cell Reports (2017) 0.75
Epigenetic regulation in cell senescence. J Mol Med (Berl) (2017) 0.75
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature (2008) 7.07
Oct4-induced pluripotency in adult neural stem cells. Cell (2009) 6.50
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res (2010) 6.03
Transcriptional profiling identifies Id2 function in dendritic cell development. Nat Immunol (2003) 2.91
DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells. Aging Cell (2009) 2.84
Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50
Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol (2014) 2.40
Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell (2009) 2.26
GM foods and the misperception of risk perception. Risk Anal (2004) 2.20
Human adult germline stem cells in question. Nature (2010) 1.74
Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation (2012) 1.71
Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks. Aging (Albany NY) (2011) 1.58
Endoscopic treatment of arachnoid cysts: a detailed account of surgical techniques and results. Neurosurgery (2010) 1.57
Modeling of asymmetric cell division in hematopoietic stem cells--regulation of self-renewal is essential for efficient repopulation. Stem Cells Dev (2009) 1.57
Epigenetic-aging-signature to determine age in different tissues. Aging (Albany NY) (2011) 1.55
Technical aids in the diagnosis of brain death: a comparison of SEP, AEP, EEG, TCD and CT angiography. Dtsch Arztebl Int (2012) 1.53
Different facets of aging in human mesenchymal stem cells. Tissue Eng Part B Rev (2010) 1.51
Specific age-associated DNA methylation changes in human dermal fibroblasts. PLoS One (2011) 1.51
Endoscopic transventricular third ventriculostomy through the lamina terminalis. J Neurosurg (2010) 1.44
Calcification or dedifferentiation: requirement to lock mesenchymal stem cells in a desired differentiation stage. J Cell Physiol (2009) 1.42
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J Clin Invest (2011) 1.39
Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population. Blood (2008) 1.39
Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation. Mol Biol Cell (2006) 1.37
Mesenchymal stem cells and cardiac repair. J Cell Mol Med (2008) 1.37
Two distinct types of Langerhans cells populate the skin during steady state and inflammation. Immunity (2012) 1.36
How to track cellular aging of mesenchymal stromal cells? Aging (Albany NY) (2010) 1.34
Pluripotent stem cells escape from senescence-associated DNA methylation changes. Genome Res (2012) 1.32
Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene. Mol Ther (2005) 1.30
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors. PLoS One (2010) 1.30
Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells. J Cell Mol Med (2009) 1.25
Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition. J Biol Chem (2010) 1.25
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. Stem Cells (2008) 1.24
Endoscopic third ventriculostomy in infants of less than 1 year of age: which factors influence the outcome? Childs Nerv Syst (2004) 1.23
Impact of individual platelet lysates on isolation and growth of human mesenchymal stromal cells. Cytotherapy (2010) 1.23
Modulation of calcium-activated potassium channels induces cardiogenesis of pluripotent stem cells and enrichment of pacemaker-like cells. Circulation (2010) 1.22
Donor age of human platelet lysate affects proliferation and differentiation of mesenchymal stem cells. PLoS One (2012) 1.18
MicroRNAs are shaping the hematopoietic landscape. Haematologica (2011) 1.17
Expansion of adipose mesenchymal stromal cells is affected by human platelet lysate and plating density. Cell Transplant (2011) 1.17
Population dynamics of mesenchymal stromal cells during culture expansion. Cytotherapy (2011) 1.16
N-cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells. Stem Cell Res (2010) 1.16
Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions. Haematologica (2010) 1.14
Stem cells and ageing. The potential of stem cells to overcome age-related deteriorations of the body in regenerative medicine. EMBO Rep (2005) 1.13
Immunoglobulin-like transcripts ILT2, ILT3 and ILT7 are expressed by human dendritic cells and down-regulated following activation. Gene (2004) 1.13
Assessment of stem cell/biomaterial combinations for stem cell-based tissue engineering. Biomaterials (2007) 1.12
Satellite-based terrestrial production efficiency modeling. Carbon Balance Manag (2009) 1.11
Parthenogenetic stem cells for tissue-engineered heart repair. J Clin Invest (2013) 1.11
Two-photon absorption and self-phase modulation measurements with shaped femtosecond laser pulses. Opt Lett (2005) 1.10
Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles. Mol Ther (2012) 1.07
Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis. Blood (2004) 1.07
Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells. Prostate (2010) 1.06
Hematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture. Sci Rep (2013) 1.04
Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration. J Gen Virol (2005) 1.04
Adipogenic differentiation of human mesenchymal stromal cells is down-regulated by microRNA-369-5p and up-regulated by microRNA-371. J Cell Physiol (2011) 1.01
CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood (2008) 1.00
GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter. Oncogene (2003) 1.00
Modeling of replicative senescence in hematopoietic development. Aging (Albany NY) (2009) 0.99
TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports (2013) 0.98
Cord blood-hematopoietic stem cell expansion in 3D fibrin scaffolds with stromal support. Biomaterials (2012) 0.98
Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics. Nat Rev Neurosci (2013) 0.97
TGF-beta1 accelerates dendritic cell differentiation from common dendritic cell progenitors and directs subset specification toward conventional dendritic cells. J Immunol (2010) 0.97
Neural induction intermediates exhibit distinct roles of Fgf signaling. Stem Cells (2010) 0.97
Membrane proteinase 3 expression in patients with Wegener's granulomatosis and in human hematopoietic stem cell-derived neutrophils. J Am Soc Nephrol (2005) 0.97
Hypoxic/normoxic preconditioning increases endothelial differentiation potential of human bone marrow CD133+ cells. Tissue Eng Part C Methods (2010) 0.96
Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide. J Neurooncol (2009) 0.96
Success and failure of endoscopic third ventriculostomy in young infants: are there different age distributions? Childs Nerv Syst (2006) 0.95
The beauty of asymmetry: asymmetric divisions and self-renewal in the haematopoietic system. Curr Opin Hematol (2007) 0.95
3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche. Biomaterials (2011) 0.95
Unilateral multilevel interlaminar fenestration instead of laminectomy or hemilaminectomy: an alternative surgical approach to intraspinal space-occupying lesions. Technical note. J Neurosurg Spine (2007) 0.94
Consequences of media information uptake and deliberation: focus groups' symbolic coping with synthetic biology. Public Underst Sci (2012) 0.94
The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity. J Immunol (2012) 0.94
Synergistic effects of growth factors and mesenchymal stromal cells for expansion of hematopoietic stem and progenitor cells. Exp Hematol (2011) 0.94
Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex. Gastroenterology (2012) 0.93
Dimerization is required for SH3PX1 tyrosine phosphorylation in response to epidermal growth factor signalling and interaction with ACK2. Biochem J (2006) 0.93