PubRank

Olaf Schneewind

Author PubWeight™ 255.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005 7.72
2 Allelic replacement in Staphylococcus aureus with inducible counter-selection. Plasmid 2005 6.11
3 Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nat Med 2007 5.95
4 Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria. Microbiol Mol Biol Rev 2006 4.88
5 Passage of heme-iron across the envelope of Staphylococcus aureus. Science 2003 4.83
6 Iron-source preference of Staphylococcus aureus infections. Science 2004 4.33
7 Targeting of alpha-hemolysin by active or passive immunization decreases severity of USA300 skin infection in a mouse model. J Infect Dis 2010 4.19
8 Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease. J Infect Dis 2008 4.16
9 Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands. J Bacteriol 2007 4.07
10 Vaccine protection against Staphylococcus aureus pneumonia. J Exp Med 2008 4.01
11 Staphylococcus aureus virulence genes identified by bursa aurealis mutagenesis and nematode killing. Proc Natl Acad Sci U S A 2004 3.89
12 Assembly of pili on the surface of Corynebacterium diphtheriae. Mol Microbiol 2003 3.79
13 Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect Immun 2006 3.41
14 Plague bacteria target immune cells during infection. Science 2005 3.32
15 Staphylococcus aureus degrades neutrophil extracellular traps to promote immune cell death. Science 2013 3.32
16 An iron-regulated sortase anchors a class of surface protein during Staphylococcus aureus pathogenesis. Proc Natl Acad Sci U S A 2002 3.23
17 Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues. FASEB J 2009 2.82
18 Sortases and pilin elements involved in pilus assembly of Corynebacterium diphtheriae. Mol Microbiol 2004 2.80
19 Assembly of pili in Gram-positive bacteria. Trends Microbiol 2004 2.76
20 Vaccine assembly from surface proteins of Staphylococcus aureus. Proc Natl Acad Sci U S A 2006 2.71
21 Staphylococcus aureus IsdB is a hemoglobin receptor required for heme iron utilization. J Bacteriol 2006 2.54
22 Protein sorting to the cell wall envelope of Gram-positive bacteria. Biochim Biophys Acta 2004 2.42
23 IsdG and IsdI, heme-degrading enzymes in the cytoplasm of Staphylococcus aureus. J Biol Chem 2003 2.39
24 Iron-regulated surface determinants (Isd) of Staphylococcus aureus: stealing iron from heme. Microbes Infect 2004 2.37
25 The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter. Cell Host Microbe 2007 2.26
26 Prophages of Staphylococcus aureus Newman and their contribution to virulence. Mol Microbiol 2006 2.20
27 Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis 2011 2.19
28 Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells. Am J Physiol Cell Physiol 2005 2.07
29 Synthesis of glycerol phosphate lipoteichoic acid in Staphylococcus aureus. Proc Natl Acad Sci U S A 2007 2.06
30 Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring. J Biol Chem 2002 1.97
31 Substrate recognition by the Yersinia type III protein secretion machinery. Mol Microbiol 2003 1.93
32 hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. Gastroenterology 2004 1.91
33 Inactivation of the srtA gene in Listeria monocytogenes inhibits anchoring of surface proteins and affects virulence. Mol Microbiol 2002 1.89
34 Staphylococcus aureus synthesizes adenosine to escape host immune responses. J Exp Med 2009 1.85
35 Rapidly progressive, fatal, inhalation anthrax-like infection in a human: case report, pathogen genome sequencing, pathology, and coordinated response. Arch Pathol Lab Med 2011 1.83
36 An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus. Nat Chem Biol 2006 1.83
37 Architects at the bacterial surface - sortases and the assembly of pili with isopeptide bonds. Nat Rev Microbiol 2011 1.79
38 Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice. J Exp Med 2010 1.77
39 The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall. Structure 2004 1.76
40 Contribution of coagulases towards Staphylococcus aureus disease and protective immunity. PLoS Pathog 2010 1.75
41 Cross-linked peptidoglycan mediates lysostaphin binding to the cell wall envelope of Staphylococcus aureus. J Bacteriol 2006 1.72
42 Assembly of pili on the surface of Bacillus cereus vegetative cells. Mol Microbiol 2007 1.67
43 Sortase as a target of anti-infective therapy. Pharmacol Rev 2008 1.64
44 Iron acquisition and transport in Staphylococcus aureus. Biometals 2006 1.61
45 BslA, a pXO1-encoded adhesin of Bacillus anthracis. Mol Microbiol 2008 1.60
46 Crystal structures of Staphylococcus aureus sortase A and its substrate complex. J Biol Chem 2004 1.60
47 Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. Cell Host Microbe 2008 1.59
48 Surface protein IsdC and Sortase B are required for heme-iron scavenging of Bacillus anthracis. J Bacteriol 2006 1.59
49 Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases. J Biol Chem 2004 1.58
50 Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood. PLoS Pathog 2011 1.57
51 LcrV plague vaccine with altered immunomodulatory properties. Infect Immun 2005 1.57
52 IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge. Vaccine 2010 1.57
53 Recurrent infections and immune evasion strategies of Staphylococcus aureus. Curr Opin Microbiol 2011 1.54
54 A play in four acts: Staphylococcus aureus abscess formation. Trends Microbiol 2011 1.53
55 Amide bonds assemble pili on the surface of bacilli. Proc Natl Acad Sci U S A 2008 1.53
56 Bacillus anthracis IsdG, a heme-degrading monooxygenase. J Bacteriol 2006 1.51
57 Targeting proteins to the cell wall of sporulating Bacillus anthracis. Mol Microbiol 2006 1.49
58 Genes required for glycolipid synthesis and lipoteichoic acid anchoring in Staphylococcus aureus. J Bacteriol 2007 1.48
59 Bacillus anthracis secretes proteins that mediate heme acquisition from hemoglobin. PLoS Pathog 2008 1.47
60 Bacillus anthracis sortase A (SrtA) anchors LPXTG motif-containing surface proteins to the cell wall envelope. J Bacteriol 2005 1.46
61 YopD and LcrH regulate expression of Yersinia enterocolitica YopQ by a posttranscriptional mechanism and bind to yopQ RNA. J Bacteriol 2002 1.44
62 On the role of Staphylococcus aureus sortase and sortase-catalyzed surface protein anchoring in murine septic arthritis. J Infect Dis 2002 1.39
63 In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nat Med 2011 1.38
64 Type iii protein secretion in yersinia species. Annu Rev Cell Dev Biol 2002 1.38
65 Signal peptides direct surface proteins to two distinct envelope locations of Staphylococcus aureus. EMBO J 2008 1.35
66 Anchor structure of staphylococcal surface proteins. V. Anchor structure of the sortase B substrate IsdC. J Biol Chem 2005 1.34
67 Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis. J Biol Chem 2001 1.33
68 Yersinia pestis caf1 variants and the limits of plague vaccine protection. Infect Immun 2008 1.32
69 Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc Natl Acad Sci U S A 2009 1.31
70 Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. Proc Natl Acad Sci U S A 2009 1.30
71 Characterization of the Yersinia enterocolitica type III secretion ATPase YscN and its regulator, YscL. J Bacteriol 2006 1.29
72 Distribution of protein A on the surface of Staphylococcus aureus. J Bacteriol 2007 1.28
73 Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection. J Antimicrob Chemother 2004 1.28
74 The YSIRK-G/S motif of staphylococcal protein A and its role in efficiency of signal peptide processing. J Bacteriol 2003 1.27
75 The role of Staphylococcus aureus sortase A and sortase B in murine arthritis. Microbes Infect 2003 1.26
76 Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus. MBio 2013 1.26
77 Sortase D forms the covalent bond that links BcpB to the tip of Bacillus cereus pili. J Biol Chem 2009 1.25
78 Secretion signal recognition by YscN, the Yersinia type III secretion ATPase. Proc Natl Acad Sci U S A 2006 1.23
79 Bacillus anthracis surface-layer proteins assemble by binding to the secondary cell wall polysaccharide in a manner that requires csaB and tagO. J Mol Biol 2010 1.21
80 Immunogenicity and protective immunity against bubonic plague and pneumonic plague by immunization of mice with the recombinant V10 antigen, a variant of LcrV. Infect Immun 2006 1.21
81 Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods. Protein Sci 2009 1.20
82 Generating a collection of insertion mutations in the Staphylococcus aureus genome using bursa aurealis. Methods Mol Biol 2008 1.19
83 Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site. Structure 2004 1.18
84 Immunization with recombinant V10 protects cynomolgus macaques from lethal pneumonic plague. Infect Immun 2008 1.18
85 Abscess formation and alpha-hemolysin induced toxicity in a mouse model of Staphylococcus aureus peritoneal infection. Infect Immun 2012 1.16
86 Yersinia enterocolitica type III secretion: yscM1 and yscM2 regulate yop gene expression by a posttranscriptional mechanism that targets the 5' untranslated region of yop mRNA. J Bacteriol 2002 1.16
87 Identifying protective antigens of Staphylococcus aureus, a pathogen that suppresses host immune responses. FASEB J 2011 1.15
88 Staphylococcus aureus mutants lacking the LytR-CpsA-Psr family of enzymes release cell wall teichoic acids into the extracellular medium. J Bacteriol 2013 1.15
89 Yersinia enterocolitica type III secretion: mutational analysis of the yopQ secretion signal. J Bacteriol 2002 1.14
90 BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis. Mol Microbiol 2009 1.14
91 Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein. J Biol Chem 2011 1.12
92 Two capsular polysaccharides enable Bacillus cereus G9241 to cause anthrax-like disease. Mol Microbiol 2011 1.11
93 Cell wall anchor structure of BcpA pili in Bacillus anthracis. J Biol Chem 2008 1.10
94 Activation of inhibitors by sortase triggers irreversible modification of the active site. J Biol Chem 2007 1.09
95 Anchoring of surface proteins to the cell wall of Staphylococcus aureus. A conserved arginine residue is required for efficient catalysis of sortase A. J Biol Chem 2004 1.09
96 Staphylococcus aureus mutants with increased lysostaphin resistance. J Bacteriol 2006 1.08
97 YscU cleavage and the assembly of Yersinia type III secretion machine complexes. Mol Microbiol 2008 1.07
98 Staphylococcus aureus secretes coagulase and von Willebrand factor binding protein to modify the coagulation cascade and establish host infections. J Innate Immun 2012 1.07
99 Protein A-specific monoclonal antibodies and prevention of Staphylococcus aureus disease in mice. Infect Immun 2012 1.06
100 Determinants of murein hydrolase targeting to cross-wall of Staphylococcus aureus peptidoglycan. J Biol Chem 2012 1.06
101 Yersinia yopQ mRNA encodes a bipartite type III secretion signal in the first 15 codons. Mol Microbiol 2003 1.06
102 Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol 2008 1.06
103 Substrate recognition of type III secretion machines--testing the RNA signal hypothesis. Cell Microbiol 2005 1.04
104 Pneumonic plague pathogenesis and immunity in Brown Norway rats. Am J Pathol 2009 1.04
105 LytN, a murein hydrolase in the cross-wall compartment of Staphylococcus aureus, is involved in proper bacterial growth and envelope assembly. J Biol Chem 2011 1.03
106 Binding of SycH chaperone to YscM1 and YscM2 activates effector yop expression in Yersinia enterocolitica. J Bacteriol 2004 1.03
107 Rejection of impassable substrates by Yersinia type III secretion machines. J Bacteriol 2005 1.03
108 Coagulases as determinants of protective immune responses against Staphylococcus aureus. Infect Immun 2012 1.02
109 Investigation of a researcher's death due to septicemic plague. N Engl J Med 2011 1.02
110 Prevention of pneumonic plague in mice, rats, guinea pigs and non-human primates with clinical grade rV10, rV10-2 or F1-V vaccines. Vaccine 2011 1.02
111 Impassable YscP substrates and their impact on the Yersinia enterocolitica type III secretion pathway. J Bacteriol 2008 1.01
112 Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA). BMC Biochem 2011 1.00
113 Sortase C-mediated anchoring of BasI to the cell wall envelope of Bacillus anthracis. J Bacteriol 2007 1.00
114 Yop fusions to tightly folded protein domains and their effects on Yersinia enterocolitica type III secretion. J Bacteriol 2002 0.99
115 The SLH-domain protein BslO is a determinant of Bacillus anthracis chain length. Mol Microbiol 2011 0.99
116 Yersinia pestis IS1541 transposition provides for escape from plague immunity. Infect Immun 2009 0.98
117 CcpA mediates proline auxotrophy and is required for Staphylococcus aureus pathogenesis. J Bacteriol 2010 0.97
118 Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus. J Biol Chem 2013 0.97
119 Release of protein A from the cell wall of Staphylococcus aureus. Proc Natl Acad Sci U S A 2014 0.96
120 Secretion genes as determinants of Bacillus anthracis chain length. J Bacteriol 2012 0.95
121 Surface-layer (S-layer) proteins sap and EA1 govern the binding of the S-layer-associated protein BslO at the cell septa of Bacillus anthracis. J Bacteriol 2012 0.94
122 Sortases make pili from three ingredients. Proc Natl Acad Sci U S A 2008 0.94
123 ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus. Mol Microbiol 2010 0.93
124 Identification of secreted bacterial proteins by noncanonical amino acid tagging. Proc Natl Acad Sci U S A 2013 0.93
125 The ttsA gene is required for low-calcium-induced type III secretion of Yop proteins and virulence of Yersinia enterocolitica W22703. J Bacteriol 2003 0.93
126 Amino acid residues 196-225 of LcrV represent a plague protective epitope. Vaccine 2009 0.93
127 Fibrin formation by staphylothrombin facilitates Staphylococcus aureus-induced platelet aggregation. Thromb Haemost 2012 0.92
128 The role of staphylothrombin-mediated fibrin deposition in catheter-related Staphylococcus aureus infections. J Infect Dis 2013 0.92
129 Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA. Mol Microbiol 2008 0.92
130 Multiple ligands of von Willebrand factor-binding protein (vWbp) promote Staphylococcus aureus clot formation in human plasma. J Biol Chem 2013 0.91
131 Plague vaccines and the molecular basis of immunity against Yersinia pestis. Hum Vaccin 2009 0.91
132 Genome sequencing and analysis of Yersina pestis KIM D27, an avirulent strain exempt from select agent regulation. PLoS One 2011 0.91
133 Penetration of the blood-brain barrier by Bacillus anthracis requires the pXO1-encoded BslA protein. J Bacteriol 2009 0.91
134 Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria. Proc Natl Acad Sci U S A 2013 0.91
135 A synonymous mutation in Yersinia enterocolitica yopE affects the function of the YopE type III secretion signal. J Bacteriol 2005 0.91
136 Exploring Staphylococcus aureus pathways to disease for vaccine development. Semin Immunopathol 2011 0.90
137 Protective immunity against plague. Adv Exp Med Biol 2007 0.89
138 The secretion signal of YopN, a regulatory protein of the Yersinia enterocolitica type III secretion pathway. J Bacteriol 2004 0.86
139 Bacillus anthracis acetyltransferases PatA1 and PatA2 modify the secondary cell wall polysaccharide and affect the assembly of S-layer proteins. J Bacteriol 2012 0.86
140 Translational regulation of Yersinia enterocolitica mRNA encoding a type III secretion substrate. J Biol Chem 2013 0.85
141 Hereditary hemochromatosis restores the virulence of plague vaccine strains. J Infect Dis 2012 0.85
142 Identification of chromosomal genes in Yersinia pestis that influence type III secretion and delivery of Yops into target cells. PLoS One 2012 0.84
143 Pili prove pertinent to enterococcal endocarditis. J Clin Invest 2006 0.84
144 Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells. Cell Microbiol 2012 0.84
145 Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Sci 2010 0.84
146 YopR impacts type III needle polymerization in Yersinia species. Mol Microbiol 2009 0.83
147 Plague in Guinea pigs and its prevention by subunit vaccines. Am J Pathol 2011 0.82
148 YfbA, a Yersinia pestis regulator required for colonization and biofilm formation in the gut of cat fleas. J Bacteriol 2014 0.82
149 Synthesis of lipoteichoic acids in Bacillus anthracis. J Bacteriol 2012 0.82
150 Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus. Mol Microbiol 2012 0.82
151 N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus bloodstream infection. J Biol Chem 2013 0.82
152 Vaccine protection against Bacillus cereus-mediated respiratory anthrax-like disease in mice. Infect Immun 2013 0.81
153 Bacillus cereus G9241 S-layer assembly contributes to the pathogenesis of anthrax-like disease in mice. J Bacteriol 2012 0.81
154 Polymorphisms in the lcrV gene of Yersinia enterocolitica and their effect on plague protective immunity. Infect Immun 2012 0.81
155 Sortase-conjugation generates a capsule vaccine that protects guinea pigs against Bacillus anthracis. Vaccine 2012 0.80
156 The giant protein Ebh is a determinant of Staphylococcus aureus cell size and complement resistance. J Bacteriol 2013 0.80
157 LcrV mutants that abolish Yersinia type III injectisome function. J Bacteriol 2012 0.80
158 Total chemical synthesis of the enzyme sortase A(ΔN59) with full catalytic activity. Angew Chem Int Ed Engl 2014 0.78
159 Ubiquitin-Yop hybrids as probes for post-translational transport by the Yersinia type III secretion pathway. Mol Microbiol 2007 0.78
160 Growth and laboratory maintenance of Staphylococcus aureus. Curr Protoc Microbiol 2013 0.76
161 Microbiology: loading the type III cannon. Nature 2005 0.75
162 Bacterial invasins: molecular systems dedicated to the invasion of host tissues. Contrib Microbiol 2005 0.75