A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division.

PubWeight™: 2.63‹?› | Rank: Top 1%

🔗 View Article (PMID 22265406)

Published in Cell on January 20, 2012

Authors

Pierre Rocheteau1, Barbara Gayraud-Morel, Irene Siegl-Cachedenier, Maria A Blasco, Shahragim Tajbakhsh

Author Affiliations

1: Institut Pasteur, Stem Cells and Development, Department of Developmental Biology, CNRS URA 2578, 25 rue du Dr. Roux, Paris 75015, France.

Articles citing this

(truncated to the top 100)

Defining the mode of tumour growth by clonal analysis. Nature (2012) 5.02

The aged niche disrupts muscle stem cell quiescence. Nature (2012) 3.46

Distinct contribution of stem and progenitor cells to epidermal maintenance. Nature (2012) 3.44

Molecular regulation of stem cell quiescence. Nat Rev Mol Cell Biol (2013) 3.07

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. Nat Med (2014) 2.99

Tissue-specific stem cells: lessons from the skeletal muscle satellite cell. Cell Stem Cell (2012) 2.68

Role of the extracellular matrix in regulating stem cell fate. Nat Rev Mol Cell Biol (2013) 2.09

A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell (2013) 2.04

DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution. Nat Methods (2012) 1.85

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration. Cell Stem Cell (2015) 1.79

Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division. Nat Med (2015) 1.76

The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells. Cell Stem Cell (2015) 1.73

Tracking chromatid segregation to identify human cardiac stem cells that regenerate extensively the infarcted myocardium. Circ Res (2012) 1.63

Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38α/β MAPK. Cell Stem Cell (2012) 1.55

Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline. Cell (2015) 1.49

Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression. Cell Metab (2014) 1.46

Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy. FASEB J (2013) 1.42

Macrophage plasticity and the role of inflammation in skeletal muscle repair. Mediators Inflamm (2013) 1.40

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword? FEBS J (2013) 1.33

Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation. Development (2012) 1.31

Dynamic binding of RBPJ is determined by Notch signaling status. Genes Dev (2013) 1.30

Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity. Nat Commun (2012) 1.24

Intrinsic and extrinsic mechanisms regulating satellite cell function. Development (2015) 1.16

Muscle satellite cell heterogeneity and self-renewal. Front Cell Dev Biol (2014) 1.09

Cellular dynamics in the muscle satellite cell niche. EMBO Rep (2013) 1.08

The central role of muscle stem cells in regenerative failure with aging. Nat Med (2015) 1.08

Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle. Cell Death Dis (2014) 1.07

Tissue-resident mesenchymal stem/progenitor cells in skeletal muscle: collaborators or saboteurs? FEBS J (2013) 1.05

Myogenic differentiation of muscular dystrophy-specific induced pluripotent stem cells for use in drug discovery. Stem Cells Transl Med (2014) 1.02

BAF60 A, B, and Cs of muscle determination and renewal. Genes Dev (2012) 1.01

Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state. Development (2014) 0.99

Restoration versus reconstruction: cellular mechanisms of skin, nerve and muscle regeneration compared. Regen Med Res (2013) 0.97

Recent progress in satellite cell/myoblast engraftment -- relevance for therapy. FEBS J (2013) 0.96

Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting. Nat Protoc (2015) 0.95

The ins and outs of muscle stem cell aging. Skelet Muscle (2016) 0.94

The emerging biology of muscle stem cells: implications for cell-based therapies. Bioessays (2012) 0.94

The satellite cell in male and female, developing and adult mouse muscle: distinct stem cells for growth and regeneration. PLoS One (2012) 0.94

Distinct contextual roles for Notch signalling in skeletal muscle stem cells. BMC Dev Biol (2014) 0.94

Stem cells for skeletal muscle regeneration: therapeutic potential and roadblocks. Transl Res (2013) 0.92

Metabolic Reprogramming of Stem Cell Epigenetics. Cell Stem Cell (2015) 0.91

Understanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversies. Tissue Barriers (2013) 0.90

Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle. Stem Cell Reports (2014) 0.90

Muscle stem cells at a glance. J Cell Sci (2014) 0.90

Tissue resident stem cells: till death do us part. Biogerontology (2013) 0.89

Chromatin features and the epigenetic regulation of pluripotency states in ESCs. Development (2014) 0.88

A role for RNA post-transcriptional regulation in satellite cell activation. Skelet Muscle (2012) 0.88

Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease. Nat Rev Mol Cell Biol (2016) 0.87

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells. Stem Cell Reports (2015) 0.87

Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets requirements of design to minimize mutation accumulation. BMC Biol (2015) 0.86

Emerging gene editing strategies for Duchenne muscular dystrophy targeting stem cells. Front Physiol (2014) 0.86

Lkb1 is indispensable for skeletal muscle development, regeneration, and satellite cell homeostasis. Stem Cells (2014) 0.85

Biomaterial-based delivery for skeletal muscle repair. Adv Drug Deliv Rev (2014) 0.85

Comparative myogenesis in teleosts and mammals. Cell Mol Life Sci (2014) 0.84

Hypoxia increases mouse satellite cell clone proliferation maintaining both in vitro and in vivo heterogeneity and myogenic potential. PLoS One (2012) 0.84

A CO-FISH assay to assess sister chromatid segregation patterns in mitosis of mouse embryonic stem cells. Chromosome Res (2013) 0.84

Stem cell activation in skeletal muscle regeneration. Cell Mol Life Sci (2015) 0.83

DNA methyltransferase-3-dependent nonrandom template segregation in differentiating embryonic stem cells. J Cell Biol (2013) 0.83

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice. PLoS One (2016) 0.83

Strand-seq: a unifying tool for studies of chromosome segregation. Semin Cell Dev Biol (2013) 0.82

Biased DNA segregation during stem cell division. Circ Res (2012) 0.82

Human satellite cells have regenerative capacity and are genetically manipulable. J Clin Invest (2014) 0.82

Tissue-specific designs of stem cell hierarchies. Nat Cell Biol (2016) 0.81

When stem cells grow old: phenotypes and mechanisms of stem cell aging. Development (2016) 0.80

Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication. FASEB J (2016) 0.80

Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development. Cell Rep (2016) 0.80

Stem cell decisions: a twist of fate or a niche market? Semin Cell Dev Biol (2014) 0.80

Concise review: stem cell therapy for muscular dystrophies. Stem Cells Transl Med (2012) 0.80

Asymmetric distribution of histones during Drosophila male germline stem cell asymmetric divisions. Chromosome Res (2013) 0.80

Sorting DNA with asymmetry: a new player in gene regulation? Chromosome Res (2013) 0.79

Sarcopenia and piscines: the case for indeterminate-growing fish as unique genetic model organisms in aging and longevity research. Front Genet (2013) 0.79

MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice. Nat Commun (2015) 0.79

Losing stem cells in the aged skeletal muscle niche. Cell Res (2013) 0.79

Monoclonal antibodies against muscle actin isoforms: epitope identification and analysis of isoform expression by immunoblot and immunostaining in normal and regenerating skeletal muscle. F1000Res (2016) 0.79

Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting. Skelet Muscle (2016) 0.78

Possible local stem cells activation by microcurrent application in experimentally injured soleus muscle. Int J Stem Cells (2014) 0.78

Self-renewal and differentiation of muscle satellite cells are regulated by the Fas-associated death domain. J Biol Chem (2013) 0.78

Regenerative Cell Therapy for Corneal Endothelium. Curr Ophthalmol Rep (2014) 0.78

The Spindle Assembly Checkpoint Safeguards Genomic Integrity of Skeletal Muscle Satellite Cells. Stem Cell Reports (2015) 0.78

Cardiac aging - Getting to the stem of the problem. J Mol Cell Cardiol (2015) 0.78

Epidermal stem cells and their epigenetic regulation. Int J Mol Sci (2013) 0.77

A muscle stem cell for every muscle: variability of satellite cell biology among different muscle groups. Front Aging Neurosci (2015) 0.77

DNA asymmetry in stem cells - immortal or mortal? J Cell Sci (2013) 0.77

Molecular regulation of determination in asymmetrically dividing muscle stem cells. Cell Cycle (2012) 0.77

Engineered matrices for skeletal muscle satellite cell engraftment and function. Matrix Biol (2016) 0.77

A Pitx2-MicroRNA Pathway Modulates Cell Proliferation in Myoblasts and Skeletal-Muscle Satellite Cells and Promotes Their Commitment to a Myogenic Cell Fate. Mol Cell Biol (2015) 0.77

Pax7 is back. Skelet Muscle (2014) 0.76

Asymmetric Distribution of Primary Cilia Allocates Satellite Cells for Self-Renewal. Stem Cell Reports (2016) 0.76

Selective tracking of template DNA strands after induction of mitosis with unreplicated genomes (MUGs) in Drosophila S2 cells. Chromosome Res (2013) 0.76

Molecular Regulation of Muscle Satellite Cell Self-Renewal. J Stem Cell Res Ther (2012) 0.76

Myospheres are composed of two cell types: one that is myogenic and a second that is mesenchymal. PLoS One (2015) 0.76

Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis. Front Cell Dev Biol (2016) 0.76

Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells Int (2016) 0.76

Disruption of mitochondrial quality control in peripheral artery disease: New therapeutic opportunities. Pharmacol Res (2016) 0.75

Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance. Stem Cells (2015) 0.75

Rejuvenating stem cells to restore muscle regeneration in aging. F1000Res (2017) 0.75

Sprouting a new take on stem cell aging. EMBO J (2012) 0.75

PAX7 is a required target for microRNA-206-induced differentiation of fusion-negative rhabdomyosarcoma. Cell Death Dis (2016) 0.75

Nutraceuticals and Their Potential to Treat Duchenne Muscular Dystrophy: Separating the Credible from the Conjecture. Nutrients (2016) 0.75

Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis. Trends Cell Biol (2016) 0.75

Enhancement of Satellite Cell Transplantation Efficiency by Leukemia Inhibitory Factor. J Neuromuscul Dis (2016) 0.75

Articles by these authors

The hallmarks of aging. Cell (2013) 14.29

Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32

Cellular senescence in cancer and aging. Cell (2007) 9.04

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature (2009) 7.96

The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature (2009) 7.39

Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nat Cell Biol (2007) 4.84

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell (2009) 4.59

Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol (2006) 4.33

The common biology of cancer and ageing. Nature (2007) 4.28

Segmenting and tracking fluorescent cells in dynamic 3-D microscopy with coupled active surfaces. IEEE Trans Image Process (2005) 4.05

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol (2005) 3.96

Delayed ageing through damage protection by the Arf/p53 pathway. Nature (2007) 3.87

Isolation and in vitro expansion of human colonic stem cells. Nat Med (2011) 3.20

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. Development (2011) 3.18

Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice. Nature (2004) 3.00

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis. FASEB J (2002) 2.96

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes Dev (2009) 2.91

Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell (2008) 2.85

Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev (2005) 2.76

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol (2008) 2.43

Global chromatin compaction limits the strength of the DNA damage response. J Cell Biol (2007) 2.40

Cancer and ageing: convergent and divergent mechanisms. Nat Rev Mol Cell Biol (2007) 2.27

TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Dev Cell (2010) 2.24

Muscle satellite cells and endothelial cells: close neighbors and privileged partners. Mol Biol Cell (2007) 2.16

Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. Dev Cell (2009) 2.10

A critical requirement for notch signaling in maintenance of the quiescent skeletal muscle stem cell state. Stem Cells (2012) 2.05

Telomere lengthening early in development. Nat Cell Biol (2007) 2.02

Kinetics of myoblast proliferation show that resident satellite cells are competent to fully regenerate skeletal muscle fibers. Exp Cell Res (2002) 2.01

Telomerase regulation and stem cell behaviour. Curr Opin Cell Biol (2006) 1.79

Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites. Nat Cell Biol (2010) 1.69

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. EMBO Mol Med (2012) 1.66

A role for the myogenic determination gene Myf5 in adult regenerative myogenesis. Dev Biol (2007) 1.61

A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs. EMBO J (2009) 1.56

The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell (2011) 1.55

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol (2008) 1.51

SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol (2010) 1.48

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping. Nat Struct Mol Biol (2010) 1.44

Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus. Development (2003) 1.41

Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres. EMBO J (2007) 1.38

Telomeres in cancer and ageing. Philos Trans R Soc Lond B Biol Sci (2011) 1.36

Centromere mitotic recombination in mammalian cells. J Cell Biol (2008) 1.35

The RNA subunit of telomerase is encoded by Marek's disease virus. J Virol (2003) 1.32

A GRFa2/Prop1/stem (GPS) cell niche in the pituitary. PLoS One (2009) 1.31

RAP1 protects from obesity through its extratelomeric role regulating gene expression. Cell Rep (2013) 1.31

Dynamic binding of RBPJ is determined by Notch signaling status. Genes Dev (2013) 1.30

The rate of increase of short telomeres predicts longevity in mammals. Cell Rep (2012) 1.26

Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity. Nat Commun (2012) 1.24

The role of telomeres and telomerase in stem cell aging. FEBS Lett (2010) 1.22

A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres. PLoS One (2009) 1.21

Role of shelterin in cancer and aging. Aging Cell (2010) 1.21

p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes. J Clin Invest (2013) 1.21

Telomere length predicts embryo fragmentation after in vitro fertilization in women--toward a telomere theory of reproductive aging in women. Am J Obstet Gynecol (2005) 1.20

TERRA transcripts are bound by a complex array of RNA-binding proteins. Nat Commun (2010) 1.19

ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase. J Cell Biol (2010) 1.17

Assessing cell and organ senescence biomarkers. Circ Res (2012) 1.17

Telomerase at the intersection of cancer and aging. Trends Genet (2013) 1.16

Skeletal muscle stem cell birth and properties. Semin Cell Dev Biol (2007) 1.15

Oxidative stress contributes to arsenic-induced telomere attrition, chromosome instability, and apoptosis. J Biol Chem (2003) 1.14

Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury. Arthritis Rheum (2010) 1.13

Beyond average: potential for measurement of short telomeres. Aging (Albany NY) (2012) 1.12

Intrinsic phenotypic diversity of embryonic and fetal myoblasts is revealed by genome-wide gene expression analysis on purified cells. Dev Biol (2007) 1.11

Myf5 and MyoD activation define independent myogenic compartments during embryonic development. Dev Biol (2003) 1.11

TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis. Mol Cell Biol (2009) 1.09

Irregular telomeres impair meiotic synapsis and recombination in mice. Proc Natl Acad Sci U S A (2004) 1.09

Skeletal muscle as a paradigm for regenerative biology and medicine. Regen Med (2009) 1.08

TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells. Nat Commun (2013) 1.07

Localization-dependent and -independent roles of SLX4 in regulating telomeres. Cell Rep (2013) 1.05

Telomerase deficiency impairs differentiation of mesenchymal stem cells. Exp Cell Res (2004) 1.05

The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder. J Affect Disord (2011) 1.04

Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma. Acta Neuropathol (2012) 1.04

Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres. J Cell Biol (2007) 1.03

Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration. J Cell Biol (2012) 1.03

Chromatin regulation and non-coding RNAs at mammalian telomeres. Semin Cell Dev Biol (2009) 1.02

Cell-autonomous Notch activity maintains the temporal specification potential of skeletal muscle stem cells. Development (2012) 1.02

Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations. Proc Natl Acad Sci U S A (2009) 1.02

Role of TRF2 in the assembly of telomeric chromatin. Cell Cycle (2008) 1.01

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas. EMBO Mol Med (2010) 1.01

Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite. Stem Cells (2009) 0.99

Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita. Blood (2012) 0.99

Developing bones are differentially affected by compromised skeletal muscle formation. Bone (2009) 0.98

An eye on the head: the development and evolution of craniofacial muscles. Development (2011) 0.97

Novel roles for telomerase in aging. Mech Ageing Dev (2006) 0.96

Telomere rejuvenation during nuclear reprogramming. Curr Opin Genet Dev (2010) 0.96

Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells. J Cell Sci (2012) 0.93

Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles. EMBO Rep (2002) 0.93

A G-quadruplex ligand with 10000-fold selectivity over duplex DNA. J Am Chem Soc (2007) 0.92

Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells. Adv Exp Med Biol (2010) 0.92

Potential of telomerase activation in extending health span and longevity. Curr Opin Cell Biol (2012) 0.92

Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4. Dev Biol (2013) 0.91

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo. Development (2006) 0.91

Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells. Proc Natl Acad Sci U S A (2011) 0.90

A metabolic signature predicts biological age in mice. Aging Cell (2012) 0.90

The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature. Development (2010) 0.90