Published in Chromosome Res on May 01, 2013
Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline. Cell (2015) 1.49
Epigenetic regulation in adult stem cells and cancers. Cell Biosci (2013) 0.88
Karyotype features of trematode Himasthla elongata. Mol Cytogenet (2016) 0.75
Translating the histone code. Science (2001) 56.77
The complex language of chromatin regulation during transcription. Nature (2007) 16.97
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell (2008) 14.17
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Genome regulation by long noncoding RNAs. Annu Rev Biochem (2012) 11.70
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet (2004) 11.31
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell (2008) 9.92
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
Mutation selection and the natural history of cancer. Nature (1975) 9.73
The epigenetic progenitor origin of human cancer. Nat Rev Genet (2006) 9.65
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79
Regulation of chromatin by histone modifications. Cell Res (2011) 8.44
Asymmetric and symmetric stem-cell divisions in development and cancer. Nature (2006) 7.32
Cellular memory and the histone code. Cell (2002) 7.30
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science (2003) 6.72
Dynamics of replication-independent histone turnover in budding yeast. Science (2007) 6.41
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell (2002) 6.25
Stems cells and the pathways to aging and cancer. Cell (2008) 5.99
Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev (2003) 5.77
Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell (1996) 5.77
RNA meets chromatin. Genes Dev (2005) 5.66
Mechanisms of asymmetric stem cell division. Cell (2008) 5.59
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. Nature (2005) 5.13
Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science (2001) 5.12
Conserved organization of centromeric chromatin in flies and humans. Dev Cell (2002) 5.06
Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nat Struct Mol Biol (2004) 4.95
Intestinal stem cells protect their genome by selective segregation of template DNA strands. J Cell Sci (2002) 4.92
Signaling network model of chromatin. Cell (2002) 4.87
Molecular signals of epigenetic states. Science (2010) 4.81
Binary switches and modification cassettes in histone biology and beyond. Nature (2003) 4.75
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science (2010) 4.72
Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science (2001) 4.69
Chromosomes can congress to the metaphase plate before biorientation. Science (2006) 4.64
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature (2007) 4.62
Asymmetric inheritance of mother versus daughter centrosome in stem cell division. Science (2007) 4.59
Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell (1999) 4.40
Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell (2004) 4.34
Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol (2006) 4.33
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair. Cell (2008) 4.14
Histone replacement marks the boundaries of cis-regulatory domains. Science (2007) 4.06
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev (2010) 4.00
Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly. Cell (2008) 3.96
Stem cells, ageing and the quest for immortality. Nature (2006) 3.89
Chromatin remodelling: the industrial revolution of DNA around histones. Nat Rev Mol Cell Biol (2006) 3.79
High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol (2007) 3.76
Centrosome misorientation reduces stem cell division during ageing. Nature (2008) 3.66
Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue. Cell Stem Cell (2010) 3.65
Transcriptional activation triggers deposition and removal of the histone variant H3.3. Genes Dev (2005) 3.57
Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase. Curr Biol (2007) 3.52
Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr Biol (2004) 3.49
DNA methylation in Drosophila melanogaster. Nature (2000) 3.46
HIRA is critical for a nucleosome assembly pathway independent of DNA synthesis. Mol Cell (2002) 3.44
Male and female Drosophila germline stem cells: two versions of immortality. Science (2007) 3.31
Characterization of a murine gene expressed from the inactive X chromosome. Nature (1991) 3.21
Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands. Development (2005) 3.14
Partitioning of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly. Science (2010) 3.13
Genomic imprinting: the emergence of an epigenetic paradigm. Nat Rev Genet (2011) 3.10
Histone H3 variants specify modes of chromatin assembly. Proc Natl Acad Sci U S A (2002) 3.06
Asymmetric centrosome inheritance maintains neural progenitors in the neocortex. Nature (2009) 3.03
Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis. Proc Natl Acad Sci U S A (2006) 2.98
Polycomb repression: from cellular memory to cellular proliferation and cancer. Biochim Biophys Acta (2002) 2.96
Processing of newly synthesized histone molecules. Science (1975) 2.95
Histone modifications defining active genes persist after transcriptional and mitotic inactivation. EMBO J (2004) 2.86
Histone chaperones: an escort network regulating histone traffic. Nat Struct Mol Biol (2007) 2.84
Histone variants, nucleosome assembly and epigenetic inheritance. Trends Genet (2004) 2.78
CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Science (2007) 2.71
A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division. Cell (2012) 2.63
Zfh-1 controls somatic stem cell self-renewal in the Drosophila testis and nonautonomously influences germline stem cell self-renewal. Cell Stem Cell (2008) 2.62
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. Mol Cell Biol (2000) 2.62
Cell type regulates selective segregation of mouse chromosome 7 DNA strands in mitosis. Science (2006) 2.50
Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science (2012) 2.50
Histone variants: deviants? Genes Dev (2005) 2.50
Major evolutionary transitions in centromere complexity. Cell (2009) 2.49
A model for specification of the left-right axis in vertebrates. Trends Genet (1994) 2.49
Argonaute slicing is required for heterochromatic silencing and spreading. Science (2006) 2.48
TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell (2012) 2.45
Functionally unequal centrosomes drive spindle orientation in asymmetrically dividing Drosophila neural stem cells. Dev Cell (2007) 2.39
Germline self-renewal requires cyst stem cells and stat regulates niche adhesion in Drosophila testes. Nat Cell Biol (2010) 2.29
Immortal strands? Give me a break. Cell (2007) 2.26
The immortal strand hypothesis: segregation and reconstruction. Cell (2007) 2.22
Mechanisms of epigenetic inheritance. Curr Opin Cell Biol (2007) 2.20
Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro. Cell (2009) 2.20
Intrinsic coupling of lagging-strand synthesis to chromatin assembly. Nature (2012) 2.18
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
The germline stem cells of Drosophila melanogaster partition DNA non-randomly. Eur J Cell Biol (2009) 2.17
Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells. EMBO J (2008) 2.14
Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation. Dev Cell (2011) 2.10
Support for the immortal strand hypothesis: neural stem cells partition DNA asymmetrically in vitro. J Cell Biol (2005) 2.08
The double face of the histone variant H3.3. Cell Res (2011) 2.00
Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information. Trends Cell Biol (2008) 1.95
Left-right dynein motor implicated in selective chromatid segregation in mouse cells. Science (2007) 1.90
Modifications to histones immediately after synthesis. J Mol Biol (1976) 1.86
Drosophila male germline stem cells do not asymmetrically segregate chromosome strands. J Cell Sci (2011) 1.83
Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell (2010) 1.82
Centromeres: unique chromatin structures that drive chromosome segregation. Nat Rev Mol Cell Biol (2011) 1.80
Signaling in stem cell niches: lessons from the Drosophila germline. J Cell Sci (2005) 1.69
Microenvironmental modulation of asymmetric cell division in human lung cancer cells. Proc Natl Acad Sci U S A (2010) 1.66
Epigenomic replication: linking epigenetics to DNA replication. Bioessays (2003) 1.66
Cosegregation of chromosomes containing immortal DNA strands in cells that cycle with asymmetric stem cell kinetics. Cancer Res (2002) 1.61
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol (2002) 6.20
dbCAN: a web resource for automated carbohydrate-active enzyme annotation. Nucleic Acids Res (2012) 4.91
Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc Natl Acad Sci U S A (2003) 4.67
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol (2004) 3.84
The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metab (2012) 3.81
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. Cell (2012) 3.77
Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage. Stem Cells (2007) 3.71
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol (2011) 3.60
Multigait soft robot. Proc Natl Acad Sci U S A (2011) 3.57
Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors. Proc Natl Acad Sci U S A (2007) 3.20
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons. Nature (2011) 3.19
Decoding global gene expression programs in liver cancer by noninvasive imaging. Nat Biotechnol (2007) 3.17
[GSDS: a gene structure display server]. Yi Chuan (2007) 3.02
Ultrafast dynamics of solute-solvent complexation observed at thermal equilibrium in real time. Science (2005) 2.88
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell (2012) 2.69
Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest (2012) 2.56
Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci U S A (2007) 2.56
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility. Nature (2013) 2.52
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Gastroenterology (2010) 2.48
Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res (2006) 2.37
Testis-specific TAF homologs collaborate to control a tissue-specific transcription program. Development (2004) 2.35
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II. Circ Res (2002) 2.27
c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo. Circ Res (2005) 2.23
Single ion-channel recordings using glass nanopore membranes. J Am Chem Soc (2007) 2.22
Mesenchymal cells of the intestinal lamina propria. Annu Rev Physiol (2011) 2.18
PlantTFDB: a comprehensive plant transcription factor database. Nucleic Acids Res (2007) 2.17
PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res (2008) 2.16
Soft robotics for chemists. Angew Chem Int Ed Engl (2011) 2.14
MSOAR: a high-throughput ortholog assignment system based on genome rearrangement. J Comput Biol (2007) 2.14
S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis. Sci Transl Med (2010) 2.13
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells. Int Immunopharmacol (2007) 2.08
Electrochemical sensing in paper-based microfluidic devices. Lab Chip (2009) 2.06
Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer (2005) 2.06
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes Dev (2006) 2.05
Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proc Natl Acad Sci U S A (2011) 1.98
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Proc Natl Acad Sci U S A (2002) 1.95
Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J Med Chem (2009) 1.92
Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proc Natl Acad Sci U S A (2002) 1.81
Increasing hyperpolarized spin lifetimes through true singlet eigenstates. Science (2009) 1.76
17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling. Circ Res (2004) 1.74
Multipath estimation in urban environments from joint GNSS receivers and LiDAR sensors. Sensors (Basel) (2012) 1.74
Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor. J Biol Chem (2008) 1.74
Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res (2007) 1.74
Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex. Mol Cell Biol (2002) 1.73
3-Methoxy-4-(4-nitro-benz-yloxy)-benzaldehyde. Acta Crystallogr Sect E Struct Rep Online (2008) 1.73
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. J Med Chem (2010) 1.73
Influenza-associated mortality in temperate and subtropical Chinese cities, 2003-2008. Bull World Health Organ (2012) 1.69
Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer. Mol Biol Cell (2007) 1.69
Regulatory T cells protect mice against coxsackievirus-induced myocarditis through the transforming growth factor beta-coxsackie-adenovirus receptor pathway. Circulation (2010) 1.66
Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq. Cell Res (2010) 1.64
The chromatin-remodeling BAF complex mediates cellular antiviral activities by promoter priming. Mol Cell Biol (2004) 1.64
Gene expression patterns in pancreatic tumors, cells and tissues. PLoS One (2007) 1.61
Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma. Carcinogenesis (2005) 1.59
Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma. Gastroenterology (2013) 1.58
Investigating the hydrogen-bonding model of urea denaturation. J Am Chem Soc (2009) 1.57
A non-cell autonomous role of E(z) to prevent germ cells from turning on a somatic cell marker. Science (2014) 1.55
Stepwise linear approach to catheter ablation of atrial fibrillation. Heart Rhythm (2007) 1.52
IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanism. Hepatology (2015) 1.52
kin-19/casein kinase Iα has dual functions in regulating asymmetric division and terminal differentiation in C. elegans epidermal stem cells. Cell Cycle (2010) 1.49
FragAnchor: a large-scale predictor of glycosylphosphatidylinositol anchors in eukaryote protein sequences by qualitative scoring. Genomics Proteomics Bioinformatics (2007) 1.49
Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII. Cell (2012) 1.49
Prevalence and trend of hepatitis C virus infection among blood donors in Chinese mainland: a systematic review and meta-analysis. BMC Infect Dis (2011) 1.48
Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways. Pflugers Arch (2007) 1.48
Fluoxetine synergys with anticancer drugs to overcome multidrug resistance in breast cancer cells. Tumour Biol (2012) 1.47
Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem (2011) 1.46
Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP. Blood (2008) 1.43
Radiogenomic analysis to identify imaging phenotypes associated with drug response gene expression programs in hepatocellular carcinoma. J Vasc Interv Radiol (2007) 1.42
Decrease of plasma N-terminal pro beta-type natriuretic peptide as a predictor of clinical improvement after cardiac resynchronization therapy for heart failure. Chin Med J (Engl) (2009) 1.42
Effects of low dietary magnesium intake on development of hypertension in stroke-prone spontaneously hypertensive rats: role of reactive oxygen species. J Hypertens (2002) 1.42
An alternative surgical approach for aortic infective endocarditis: vegetectomy. Eur J Cardiothorac Surg (2009) 1.40
De novo assembly and characterization of the root transcriptome of Aegilops variabilis during an interaction with the cereal cyst nematode. BMC Genomics (2012) 1.40
A new method to quantify coronary calcification by intravascular ultrasound - the different patterns of calcification of acute myocardial infarction, unstable angina pectoris and stable angina pectoris. J Invasive Cardiol (2008) 1.39
Monovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis. Genome Biol (2010) 1.38
An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma. Oncogene (2005) 1.38
Positive feedback between mycorrhizal fungi and plants influences plant invasion success and resistance to invasion. PLoS One (2010) 1.38
Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development. Gastroenterology (2010) 1.38
Intracardiac leiomyomatosis: a comprehensive analysis of 194 cases. Interact Cardiovasc Thorac Surg (2013) 1.36
Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer. Hepatology (2008) 1.35
Microarray based analysis of microRNA expression in rat cerebral cortex after traumatic brain injury. Brain Res (2009) 1.34
Either part of a Drosophila epsin protein, divided after the ENTH domain, functions in endocytosis of delta in the developing eye. Curr Biol (2003) 1.33
Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart. J Biol Chem (2004) 1.33
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One (2012) 1.32
Bifurcation of Arabidopsis NLR immune signaling via Ca²⁺-dependent protein kinases. PLoS Pathog (2013) 1.30
Rapid automated diagnosis of diabetic peripheral neuropathy with in vivo corneal confocal microscopy. Invest Ophthalmol Vis Sci (2014) 1.30
Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning. Am J Physiol Heart Circ Physiol (2008) 1.30
Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours. Carcinogenesis (2005) 1.30
DOOR 2.0: presenting operons and their functions through dynamic and integrated views. Nucleic Acids Res (2013) 1.26
tRNA-dependent pre-transfer editing by prokaryotic leucyl-tRNA synthetase. J Biol Chem (2009) 1.25
Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection. PLoS One (2008) 1.24
A gene expression signature of genetic instability in colon cancer. Cancer Res (2005) 1.23
Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer. Gastroenterology (2004) 1.23
Deriving an ontology for human gene expression sources from the CYTOMER database on human organs and cell types. In Silico Biol (2005) 1.23
Topological and functional discovery in a gene coexpression meta-network of gastric cancer. Cancer Res (2006) 1.22
MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice. FEBS Lett (2009) 1.22
DCDB: drug combination database. Bioinformatics (2009) 1.21
Repeatability of in vivo corneal confocal microscopy to quantify corneal nerve morphology. Cornea (2013) 1.21
The nuclear lamina regulates germline stem cell niche organization via modulation of EGFR signaling. Cell Stem Cell (2013) 1.19