Published in Lipids on January 24, 2012
Mechanisms for the prevention of vitamin E excess. J Lipid Res (2013) 1.11
Nonlinear absorption kinetics of self-emulsifying drug delivery systems (SEDDS) containing tocotrienols as lipophilic molecules: in vivo and in vitro studies. AAPS J (2013) 0.81
Vitamin E transporters in cancer therapy. AAPS J (2014) 0.75
Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability. Int J Nanomedicine (2013) 0.75
Profiling gene expression in human placentae of different gestational ages: an OPRU Network and UW SCOR Study. Reprod Sci (2008) 1.25
Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models. Cancer Lett (2012) 1.16
A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis. PLoS One (2009) 1.11
Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity. Exp Biol Med (Maywood) (2005) 1.06
Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease. J Alzheimers Dis (2012) 1.04
Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies. ACS Chem Neurosci (2013) 0.98
(-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers. Planta Med (2011) 0.97
Hydrophilic matrices: application of Placket-Burman screening design to model the effect of POLYOX-carbopol blends on drug release. Int J Pharm (2006) 0.94
Paclitaxel loaded PEG(5000)-DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and toxicological evaluation. Eur J Pharm Biopharm (2011) 0.93
Endoplasmic reticulum stress mediates gamma-tocotrienol-induced apoptosis in mammary tumor cells. Apoptosis (2009) 0.91
Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant nonhuman primate. J Nucl Med (2009) 0.91
Role of caspase-8 activation in mediating vitamin E-induced apoptosis in murine mammary cancer cells. Nutr Cancer (2003) 0.91
Dissolution and powder flow characterization of solid self-emulsified drug delivery system (SEDDS). Int J Pharm (2008) 0.91
D-optimal mixture design: optimization of ternary matrix blends for controlled zero-order drug release from oral dosage forms. Drug Dev Ind Pharm (2006) 0.91
Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells. Exp Biol Med (Maywood) (2004) 0.91
Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines. Eur J Pharm Sci (2012) 0.90
Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. Lipids (2007) 0.90
Role of ABC transporters in the pathogenesis of Alzheimer's disease. ACS Chem Neurosci (2012) 0.90
Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells. BMC Cancer (2010) 0.90
Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling. Biomed Pharmacother (2009) 0.90
Masitinib antagonizes ATP-binding cassette subfamily C member 10-mediated paclitaxel resistance: a preclinical study. Mol Cancer Ther (2014) 0.89
The value of tocotrienols in the prevention and treatment of cancer. J Am Coll Nutr (2010) 0.89
Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand- and structure-based virtual screening. J Med Chem (2010) 0.87
Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells. Anticancer Res (2010) 0.86
Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease. J Pharm Pharmacol (2011) 0.86
Comparison of the intestinal absorption and bioavailability of γ-tocotrienol and α-tocopherol: in vitro, in situ and in vivo studies. Biopharm Drug Dispos (2012) 0.85
Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling. Org Biomol Chem (2014) 0.85
Measurement of surface color as an expedient QC method for the detection of deviations in tablet hardness. Int J Pharm (2007) 0.84
Development and validation of a reversed-phase HPLC method for the determination of γ-tocotrienol in rat and human plasma. Biomed Chromatogr (2010) 0.84
PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication. J Drug Target (2014) 0.83
Thyroid hormone, glucocorticoids, and prolactin at the nexus of physiology, reproduction, and toxicology. Toxicol Appl Pharmacol (2004) 0.83
Genomics and pharmacogenomics of breast cancer: current knowledge and trends. Asian Pac J Cancer Prev (2011) 0.83
Novel use of Eudragit NE 30D/Eudragit L 30D-55 blends as functional coating materials in time-delayed drug release applications. Int J Pharm (2008) 0.83
Molecular interaction and localization of tocotrienol-rich fraction (TRF) within the matrices of lipid nanoparticles: evidence studies by Differential Scanning Calorimetry (DSC) and Proton Nuclear Magnetic Resonance spectroscopy ((1)H NMR). Colloids Surf B Biointerfaces (2010) 0.83
Molecular modelling and multisimplex optimization of tocotrienol-rich self emulsified drug delivery systems. Int J Pharm (2012) 0.82
Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine. J Nat Prod (2004) 0.82
Intestinal absorption of gamma-tocotrienol is mediated by Niemann-Pick C1-like 1: in situ rat intestinal perfusion studies. Drug Metab Dispos (2010) 0.82
Preparation, characterization, and anticancer effects of simvastatin-tocotrienol lipid nanoparticles. Int J Pharm (2010) 0.82
Tocotrienol-induced cytotoxicity is unrelated to mitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells. Biochem Cell Biol (2005) 0.82
The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling. Bioorg Med Chem (2009) 0.82
Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors. J Nat Prod (2009) 0.82
Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products. Food Chem Toxicol (2011) 0.81
Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines. Fitoterapia (2012) 0.81
Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. Lipids (2009) 0.81
Nonlinear absorption kinetics of self-emulsifying drug delivery systems (SEDDS) containing tocotrienols as lipophilic molecules: in vivo and in vitro studies. AAPS J (2013) 0.81
"Vitamin E" fortified parenteral lipid emulsions: Plackett-Burman screening of primary process and composition parameters. Drug Dev Ind Pharm (2012) 0.80
Antiproliferative triterpenes from Melaleuca ericifolia. J Nat Prod (2008) 0.80
Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1. Exp Biol Med (Maywood) (2009) 0.80
Stability and in vitro antiproliferative activity of bioactive "Vitamin E" fortified parenteral lipid emulsions. Colloids Surf B Biointerfaces (2012) 0.80
Mechanisms Mediating the Synergistic Anticancer Effects of Combined γ-Tocotrienol and Celecoxib Treatment. J Bioanal Biomed (2011) 0.80
Fluid bed coating: the utility of dual programmable pumps for controlled gradient drug deposition on pellets. Int J Pharm (2007) 0.80
Enhanced solubility and oral bioavailability of γ-tocotrienol using a self-emulsifying drug delivery system (SEDDS). Lipids (2014) 0.80
Experimental models for predicting drug absorption and metabolism. Expert Opin Drug Metab Toxicol (2013) 0.80
Sinulodurins A and B, antiproliferative and anti-invasive diterpenes from the soft coral Sinularia dura. J Nat Prod (2008) 0.80
Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors. Bioorg Med Chem (2010) 0.80
Mechanisms mediating the synergistic anticancer effects of combined γ-tocotrienol and sesamin treatment. Planta Med (2012) 0.79
Hard gelatin and hypromellose (HPMC) capsules: estimation of rupture time by real-time dissolution spectroscopy. Drug Dev Ind Pharm (2007) 0.79
Entrapment into nanoemulsions potentiates the anticancer activity of tocotrienols against the highly malignant (+SA) mouse mammary epithelial cells. J Nanosci Nanotechnol (2014) 0.79
Determination of methamphetamine and amphetamine in abusers' plasma and hair samples with HPLC-FL. Biomed Chromatogr (2003) 0.79
Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity. J Pharm Pharm Sci (2011) 0.79
In silico modeling for the nonlinear absorption kinetics of UK-343,664: a P-gp and CYP3A4 substrate. Mol Pharm (2012) 0.79
In vitro investigation of amyloid-β hepatobiliary disposition in sandwich-cultured primary rat hepatocytes. Drug Metab Dispos (2013) 0.78
HPLC determination of phenylpropanolamine in pharmaceutical OTC preparations. Biomed Chromatogr (2002) 0.78
Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: in vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells. Int J Pharm (2010) 0.78
Thermoresponsive fluconazole gels for topical delivery: rheological and mechanical properties, in vitro drug release and anti-fungal efficacy. Pharm Dev Technol (2013) 0.78
Modeling the effect of sonication parameters on size and dispersion temperature of solid lipid nanoparticles (SLNs) by response surface methodology (RSM). Pharm Dev Technol (2013) 0.78
Effect of gel composition and phonophoresis on the transdermal delivery of ibuprofen: in vitro and in vivo evaluation. Pharm Dev Technol (2010) 0.78
Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol. J Nat Prod (2008) 0.77
Effect of Eudragit RS 30D and talc powder on verapamil hydrochloride release from beads coated with drug layered matrices. AAPS PharmSciTech (2008) 0.77
Doxorubicin and MBO-asGCS oligonucleotide loaded lipid nanoparticles overcome multidrug resistance in adriamycin resistant ovarian cancer cells (NCI/ADR-RES). Int J Pharm (2012) 0.77
Effect of PEG surface conformation on anticancer activity and blood circulation of nanoemulsions loaded with tocotrienol-rich fraction of palm oil. AAPS J (2013) 0.77
Repeated cocaine decreases the avoidance response to a novel aversive stimulus in rats. Psychopharmacology (Berl) (2002) 0.76