Take it and release it: The use of the Rab1 small GTPase at a bacterium's will.

The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway. MBio (2015) 0.82

Bringing host-cell takeover by pathogenic bacteria to center stage. Cell Logist (2011) 0.78

Legionella and Legionnaires' disease: 25 years of investigation. Clin Microbiol Rev (2002) 7.42

Biogenesis, architecture, and function of bacterial type IV secretion systems. Annu Rev Microbiol (2005) 6.16

Physiological functions of the HECT family of ubiquitin ligases. Nat Rev Mol Cell Biol (2009) 5.43

Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer. Proc Natl Acad Sci U S A (2004) 4.27

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat Rev Microbiol (2008) 4.09

Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites. Nat Cell Biol (2002) 3.98

Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature (2007) 3.81

AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science (2008) 3.44

The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat Cell Biol (2006) 3.08

Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila. Dev Cell (2006) 3.06

Modulation of host cell function by Legionella pneumophila type IV effectors. Annu Rev Cell Dev Biol (2010) 2.92

How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: implications for conversion of plasma membrane to the ER membrane. J Cell Sci (2001) 2.83

The fic domain: regulation of cell signaling by adenylylation. Mol Cell (2009) 2.73

The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science (2010) 2.73

Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J Exp Med (2004) 2.67

Type IV secretion systems and their effectors in bacterial pathogenesis. Curr Opin Microbiol (2006) 2.65

A bifunctional bacterial protein links GDI displacement to Rab1 activation. Science (2007) 2.60

Temporal regulation of salmonella virulence effector function by proteasome-dependent protein degradation. Cell (2003) 2.60

Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages. Annu Rev Microbiol (2000) 2.50

Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. PLoS One (2011) 2.37

Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system. Infect Immun (2004) 2.25

Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J Biol Chem (2008) 2.11

De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila. Science (2011) 1.98

Legionella pneumophila SidD is a deAMPylase that modifies Rab1. Nature (2011) 1.96

AMPylation: Something Old is New Again. Front Microbiol (2010) 1.29

AMPylation is a new post-translational modiFICation. Nat Chem Biol (2009) 1.04

Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. PLoS One (2011) 2.37

Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc Natl Acad Sci U S A (2007) 1.96

Legionella pneumophila SidD is a deAMPylase that modifies Rab1. Nature (2011) 1.96

Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. PLoS Pathog (2011) 1.78

Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii. Proc Natl Acad Sci U S A (2010) 1.67

Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector. PLoS Pathog (2010) 1.59

The Legionella pneumophila effector SidJ is required for efficient recruitment of endoplasmic reticulum proteins to the bacterial phagosome. Infect Immun (2006) 1.54

The E Block motif is associated with Legionella pneumophila translocated substrates. Cell Microbiol (2010) 1.51

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination. Proc Natl Acad Sci U S A (2011) 1.42

Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cell Microbiol (2009) 1.36

Members of a Legionella pneumophila family of proteins with ExoU (phospholipase A) active sites are translocated to target cells. Infect Immun (2006) 1.36

AidH, an alpha/beta-hydrolase fold family member from an Ochrobactrum sp. strain, is a novel N-acylhomoserine lactonase. Appl Environ Microbiol (2010) 1.11

Cell biology of infection by Legionella pneumophila. Microbes Infect (2012) 1.10

Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death. Proc Natl Acad Sci U S A (2011) 1.08

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase. Proc Natl Acad Sci U S A (2012) 1.07

An in vivo gene deletion system for determining temporal requirement of bacterial virulence factors. Proc Natl Acad Sci U S A (2008) 1.03

Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants. Cell Microbiol (2007) 1.00

Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation. J Bacteriol (2013) 1.00

Domains formed within the N-terminal region of the quorum-sensing activator TraR are required for transcriptional activation and direct interaction with RpoA from agrobacterium. J Biol Chem (2004) 0.88

Induction of caspase 3 activation by multiple Legionella pneumophila Dot/Icm substrates. Cell Microbiol (2013) 0.85

Genome Sequence of an Environmental Isolate of the Bacterial Pathogen Legionella pneumophila. Genome Announc (2013) 0.79

Induction of rapid cell death by an environmental isolate of Legionella pneumophila in mouse macrophages. Infect Immun (2013) 0.77

Methods for determining protein translocation by the Legionella pneumophila Dot/Icm type IV secretion system. Methods Mol Biol (2013) 0.76

Effector translocation by the Legionella Dot/Icm type IV secretion system. Curr Top Microbiol Immunol (2013) 0.75

Legionella pneumophila infection of Drosophila S2 cells induces only minor changes in mitochondrial dynamics. PLoS One (2013) 0.75