Published in J Lipid Res on February 04, 2012
Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discov (2012) 1.71
Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent. Proc Natl Acad Sci U S A (2014) 0.88
Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm. J Lipid Res (2013) 0.87
Cancer-associated fibroblasts in digestive tumors. World J Gastroenterol (2014) 0.87
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COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset. Proc Natl Acad Sci U S A (2015) 0.83
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Modulation of type II TGF-β receptor degradation by integrin-linked kinase. J Invest Dermatol (2014) 0.77
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Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nat Med (2001) 2.98
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Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res (1992) 2.47
Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression. Semin Cell Dev Biol (2009) 2.25
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Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps. Cancer Res (2002) 2.00
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Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer. Clin Cancer Res (2001) 1.79
Prostaglandin E synthase. Prostaglandins Other Lipid Mediat (2002) 1.65
Microsomal prostaglandin E synthase-1, which is not coupled to a particular cyclooxygenase isoenzyme, is essential for prostaglandin E(2) biosynthesis in vascular smooth muscle cells. J Thromb Haemost (2007) 1.58
Prostaglandin E synthase: a novel drug target for inflammation and cancer. Curr Pharm Des (2006) 1.54
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Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer. Clin Cancer Res (2001) 1.39
Cyclooxygenase-2: a therapeutic target in angiogenesis. Trends Mol Med (2003) 1.38
Thy-1-integrin alphav beta5 interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-beta1 activation and myofibroblast differentiation. J Biol Chem (2010) 1.25
Rate of vasoconstrictor prostanoids released by endothelial cells depends on cyclooxygenase-2 expression and prostaglandin I synthase activity. Circ Res (1998) 1.22
Expression of COX-2 and PGE synthase and synthesis of PGE(2)in endometrial adenocarcinoma: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. Br J Cancer (2001) 1.09
Polymorphonuclear neutrophils and cancer: intense and sustained neutrophilia as a treatment against solid tumors. Med Res Rev (2011) 1.07
Cyclooxygenase and 5-lipoxygenase pathways in the vessel wall: role in atherosclerosis. Med Res Rev (2004) 1.07
PGE2 induces angiogenesis via MT1-MMP-mediated activation of the TGFbeta/Alk5 signaling pathway. Blood (2008) 1.05
Human vascular smooth muscle cells but not endothelial cells express prostaglandin E synthase. Circ Res (2000) 1.01
IL-1beta induces VEGF, independently of PGE2 induction, mainly through the PI3-K/mTOR pathway in renal mesangial cells. Kidney Int (2006) 0.97
Immunohistochemical study on overexpression of cyclooxygenase-2 in squamous cell carcinoma of the oral cavity: its importance as a prognostic predictor. Oral Oncol (2003) 0.94
COX-2 limits prostanoid production in activated HUVECs and is a source of PGH2 for transcellular metabolism to PGE2 by tumor cells. Arterioscler Thromb Vasc Biol (2009) 0.94
Prostaglandins in squamous cell carcinoma of the head and neck: a preliminary study. Laryngoscope (1985) 0.92
Cyclooxygenase-2 and microsomal prostaglandin E synthase-1 are overexpressed in squamous cell carcinoma of the penis. Clin Cancer Res (2004) 0.92
Regulation of cyclooxygenase catalysis by hydroperoxides. Biochem Biophys Res Commun (2005) 0.91
Experimental approaches to the study of cancer-stroma interactions: recent findings suggest a pivotal role for stroma in carcinogenesis. Lab Invest (2007) 0.90
Prostaglandin E(2) pathway in head and neck squamous cell carcinoma. Head Neck (2008) 0.89
Tumour cell lines HT-29 and FaDu produce proinflammatory cytokines and activate neutrophils in vitro: possible applications for neutrophil-based antitumour treatment. Mediators Inflamm (2010) 0.88
Increased PGE2 levels in nonmalignant mucosa adjacent to squamous cell carcinoma of the head and neck. ORL J Otorhinolaryngol Relat Spec (2005) 0.84
Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. J Biol Chem (1995) 0.83
The fibronectin synergy site modulates TGF-beta-dependent fibroblast contraction. Biochem Biophys Res Commun (2007) 0.82
COX-2 inhibitors and cardiovascular risk. Inferences based on biology and clinical studies. Thromb Haemost (2006) 0.79
Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta. J Invest Dermatol (1996) 0.76
Proposal for revision of the European Laryngological Society classification of endoscopic cordectomies. Eur Arch Otorhinolaryngol (2007) 2.30
The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation. J Cell Biochem (2006) 2.03
Second, third, and fourth head and neck tumors. A progressive decrease in survival. Head Neck (2012) 1.97
Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring. Clin Infect Dis (2005) 1.70
The role of type of tobacco and type of alcoholic beverage in oral carcinogenesis. Int J Cancer (2004) 1.63
Intronic RNAs mediate EZH2 regulation of epigenetic targets. Nat Struct Mol Biol (2012) 1.56
Lymphadenopathy caused by Mycobacterium colombiense. J Clin Microbiol (2008) 1.20
Polymorphonuclear neutrophils and cancer: intense and sustained neutrophilia as a treatment against solid tumors. Med Res Rev (2011) 1.07
Hypothyroidism in patients treated with total laryngectomy. A multivariate study. Eur Arch Otorhinolaryngol (2002) 1.02
NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis. Blood (2011) 1.01
Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential. Circ Res (2004) 1.00
Variability in nerve patterns of the adductor muscle group supplied by the recurrent laryngeal nerve. Laryngoscope (2005) 0.99
Structural insights into the activation mechanism of melibiose permease by sodium binding. Proc Natl Acad Sci U S A (2010) 0.99
Inclusion of extracapsular spread in the pTNM classification system: a proposal for patients with head and neck carcinoma. JAMA Otolaryngol Head Neck Surg (2013) 0.96
Is the external laryngeal nerve an exclusively motor nerve? The cricothyroid connection branch. Laryngoscope (2003) 0.96
The effect of waiting time on local control and survival in head and neck carcinoma patients treated with radiotherapy. Radiother Oncol (2003) 0.94
Influence of the persistence of tobacco and alcohol use in the appearance of second neoplasm in patients with a head and neck cancer. A case-control study. Cancer Causes Control (2008) 0.94
Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer. Int J Cancer (2008) 0.93
Electronegative LDL of FH subjects: chemical characterization and induction of chemokine release from human endothelial cells. Atherosclerosis (2003) 0.93
Tumor cells induce COX-2 and mPGES-1 expression in microvascular endothelial cells mainly by means of IL-1 receptor activation. Microvasc Res (2011) 0.92
Wide proinflammatory effect of electronegative low-density lipoprotein on human endothelial cells assayed by a protein array. Biochim Biophys Acta (2006) 0.92
Metachronous second primary tumours in the aerodigestive tract in patients with early stage head and neck squamous cell carcinomas. Eur Arch Otorhinolaryngol (2005) 0.90
Comparison of the Radiation Therapy Oncology Group recursive partitioning classification and Union Internationale Contre le Cancer TNM classification for patients with head and neck carcinoma. Head Neck (2005) 0.90
Regulator of calcineurin 1 mediates pathological vascular wall remodeling. J Exp Med (2011) 0.90
Paraffin-embedded cell line microarray (PECLIMA): development and validation of a high-throughput method for antigen profiling of cell lines. Pathobiology (2005) 0.90
Prostaglandin E(2) pathway in head and neck squamous cell carcinoma. Head Neck (2008) 0.89
Raman imaging of floating cells. Opt Express (2005) 0.89
Endoscopic supraglottic laryngectomy: a proposal for a classification by the working committee on nomenclature, European Laryngological Society. Eur Arch Otorhinolaryngol (2009) 0.89
Tumour cell lines HT-29 and FaDu produce proinflammatory cytokines and activate neutrophils in vitro: possible applications for neutrophil-based antitumour treatment. Mediators Inflamm (2010) 0.88
Increased lysophosphatidylcholine and non-esterified fatty acid content in LDL induces chemokine release in endothelial cells. Relationship with electronegative LDL. Atherosclerosis (2004) 0.88
Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm. J Lipid Res (2013) 0.87
Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets. Carcinogenesis (2009) 0.87
Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuli. J Lipid Res (2011) 0.85
Dual activation of pathways regulated by steroid receptors and peptide growth factors in primary prostate cancer revealed by Factor Analysis of microarray data. BMC Genomics (2005) 0.83
Supracricoid laryngectomy as salvage surgery after failure of radiation therapy. Eur Arch Otorhinolaryngol (2007) 0.83
Variability of the nerve supply patterns of the human posterior cricoarytenoid muscle. Laryngoscope (2003) 0.83
Incidence and significance of clinically unsuspected thyroid tissue in lymph nodes found during neck dissection in head and neck carcinoma patients. Laryngoscope (2005) 0.83
European Laryngological Society: ELS recommendations for the follow-up of patients treated for laryngeal cancer. Eur Arch Otorhinolaryngol (2014) 0.83
High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma. Cancer Med (2013) 0.82
Lipid metabolism in liver of rat exposed to cadmium. Food Chem Toxicol (2008) 0.82
Parotidectomies in benign parotid tumours: "Sant Pau" surgical extension classification. Acta Otorrinolaringol Esp (2009) 0.82
Regulation of aurora B kinase by the lipid raft protein flotillin-1. J Biol Chem (2010) 0.81
Risk of third and fourth tumors in patients with head and neck cancer. Head Neck (2010) 0.81
Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy. J Pathol (2015) 0.81
Retinoic acid induces PGI synthase expression in human endothelial cells. J Lipid Res (2008) 0.81
Overexpression of the nuclear factor-kappa B (p65) in association with local failure in patients with head and neck carcinoma undergong radiotherapy or chemoradiotherapy. Head Neck (2012) 0.81
A major role for RCAN1 in atherosclerosis progression. EMBO Mol Med (2013) 0.80
Identification of somatic VHL gene mutations in sporadic head and neck paragangliomas in association with activation of the HIF-1α/miR-210 signaling pathway. J Clin Endocrinol Metab (2013) 0.80
What is your diagnosis? Testicular torsion. J Am Vet Med Assoc (2011) 0.80
Prognostic role of MMP-9 expression in head and neck carcinoma patients treated with radiotherapy or chemoradiotherapy. Oral Oncol (2012) 0.80
Hepoxilin B3 and its enzymatically formed derivative trioxilin B3 are incorporated into phospholipids in psoriatic lesions. J Invest Dermatol (2002) 0.80
Novel triiodophenol derivatives induce caspase-independent mitochondrial cell death in leukemia cells inhibited by Myc. Mol Cancer Ther (2006) 0.80
Mutation analysis of the SDHD gene in four kindreds with familial paraganglioma: description of one novel germline mutation. Diagn Mol Pathol (2005) 0.80
Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk. Atherosclerosis (2012) 0.80
In-plane and out-of-plane infrared difference spectroscopy unravels tilting of helices and structural changes in a membrane protein upon substrate binding. J Am Chem Soc (2009) 0.80
What is your diagnosis? Lung lobe torsion. J Am Vet Med Assoc (2013) 0.79
Ultrasonographic anatomy of the temporomandibular joint in healthy pure-bred Spanish horses. Vet Radiol Ultrasound (2007) 0.79
Potential structures that could be confused with a nonrecurrent inferior laryngeal nerve: an anatomic study. Laryngoscope (2008) 0.79
Bemiparin: second-generation, low-molecular-weight heparin for treatment and prophylaxis of venous thromboembolism. Expert Rev Cardiovasc Ther (2008) 0.79
In vivo ectopic implantation model to assess human mesenchymal progenitor cell potential. Stem Cell Rev (2013) 0.79
Results of an organ preservation protocol with induction chemotherapy and radiotherapy in patients with locally advanced laryngeal carcinoma. Eur Arch Otorhinolaryngol (2004) 0.79
[Diagnosis and treatment of functional oropharyngeal dysphagia. Features of interest to the digestive surgeon]. Cir Esp (2007) 0.78
Prognostic factors in head and neck squamous cell carcinoma: comparison of CHAID decision trees technology and Cox analysis. Head Neck (2012) 0.78
Modification of prostanoid secretion in endothelial cells by amphotericin B acting synergistically with interleukin-1beta: possible explanation of proinflammatory effects. J Infect Dis (2004) 0.78
Imidazolineoxyl N-oxide prevents the impairment of vascular contraction caused by interleukin-1beta through several mechanisms. J Infect Dis (2003) 0.78
Development and (pre-) clinical assessment of a novel surgical tool for primary and secondary tracheoesophageal puncture with immediate voice prosthesis insertion, the Provox Vega Puncture Set. Eur Arch Otorhinolaryngol (2012) 0.78
Antimicrobial peptides incorporating non-natural amino acids as agents for plant protection. Protein Pept Lett (2014) 0.78
[Two cases of intraparotid facial nerve schwannoma]. Acta Otorrinolaringol Esp (2010) 0.78
Effects of altering the sequence of midazolam and propofol during co-induction of anaesthesia. Vet Anaesth Analg (2013) 0.77
What is your diagnosis? Pneumopericardium. J Am Vet Med Assoc (2010) 0.77
Comparison of chi-squared automatic interaction detection classification trees vs TNM classification for patients with head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2012) 0.77
Studying substrate binding to reconstituted secondary transporters by attenuated total reflection infrared difference spectroscopy. Methods Mol Biol (2012) 0.77