PubRank

Moshe Arditi

Author PubWeight™ 103.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc Natl Acad Sci U S A 2004 5.58
2 Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 2012 5.08
3 Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol 2005 4.28
4 TLR signaling in the gut in health and disease. J Immunol 2005 3.51
5 Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J Immunol 2003 2.96
6 The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis. J Immunol 2006 2.83
7 Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine. Gastroenterology 2006 2.78
8 HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med 2009 2.56
9 TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J Biol Chem 2002 2.37
10 Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest 2005 2.07
11 Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells. J Immunol 2004 2.05
12 Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling. J Immunol 2006 1.88
13 Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection. J Infect Dis 2011 1.86
14 Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections. J Exp Med 2003 1.83
15 Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J Immunol 2002 1.82
16 Toll-like receptor 2 (TLR2) and TLR9 signaling results in HIV-long terminal repeat trans-activation and HIV replication in HIV-1 transgenic mouse spleen cells: implications of simultaneous activation of TLRs on HIV replication. J Immunol 2003 1.78
17 Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One 2009 1.74
18 Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease. Circulation 2012 1.70
19 TLR signaling: an emerging bridge from innate immunity to atherogenesis. J Immunol 2004 1.62
20 The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection. PLoS Pathog 2009 1.58
21 MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia. J Biol Chem 2005 1.47
22 TLR signaling at the intestinal epithelial interface. J Endotoxin Res 2003 1.47
23 Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling. J Biol Chem 2004 1.46
24 IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice. J Immunol 2010 1.36
25 Mycobacterium tuberculosis heat shock proteins use diverse Toll-like receptor pathways to activate pro-inflammatory signals. J Biol Chem 2005 1.34
26 Innate immunity and toll-like receptors: clinical implications of basic science research. J Pediatr 2004 1.28
27 Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer. PLoS One 2010 1.26
28 Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One 2011 1.25
29 TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J Immunol 2008 1.22
30 Mastoparan, a G protein agonist peptide, differentially modulates TLR4- and TLR2-mediated signaling in human endothelial cells and murine macrophages. J Immunol 2005 1.14
31 TLR2 and MyD88 contribute to Lactobacillus casei extract-induced focal coronary arteritis in a mouse model of Kawasaki disease. Circulation 2005 1.14
32 Toll-like receptors and innate immunity in gut homeostasis and pathology. Curr Opin Hematol 2007 1.10
33 Activated myeloid dendritic cells accumulate and co-localize with CD3+ T cells in coronary artery lesions in patients with Kawasaki disease. Exp Mol Pathol 2007 1.08
34 Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking Kawasaki disease. J Immunol 2009 1.07
35 Chlamydia heat shock protein 60 induces trophoblast apoptosis through TLR4. J Immunol 2006 1.06
36 Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria. J Immunol 2011 1.05
37 Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med 2012 1.05
38 Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation. J Immunol 2008 1.02
39 TB, or not TB: that is the question -- does TLR signaling hold the answer? J Clin Invest 2004 1.01
40 Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. PLoS One 2010 1.00
41 Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest 2015 1.00
42 Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells. Eur J Immunol 2008 0.99
43 Emerging role of IL-17 in atherosclerosis. J Innate Immun 2010 0.99
44 Role of Toll-like receptors in atherosclerosis. Circ Res 2004 0.98
45 Innate immune responses during respiratory tract infection with a bacterial pathogen induce allergic airway sensitization. J Allergy Clin Immunol 2008 0.96
46 The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury. Am J Respir Cell Mol Biol 2014 0.95
47 Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human and murine vascular endothelial cells. J Endotoxin Res 2007 0.94
48 The role of innate immunity in the pathogenesis of asthma: evidence for the involvement of Toll-like receptor signaling. J Endotoxin Res 2007 0.91
49 TLR signaling and trapped vascular dendritic cells in the development of atherosclerosis. Trends Immunol 2006 0.91
50 Chlamydial heat shock protein 60 induces acute pulmonary inflammation in mice via the Toll-like receptor 4- and MyD88-dependent pathway. Infect Immun 2009 0.89
51 Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome. Microbes Infect 2012 0.89
52 Toll-like receptor signaling and atherosclerosis. Curr Opin Hematol 2006 0.88
53 Regulation of Toll-like receptor 2 interaction with Ecgp96 controls Escherichia coli K1 invasion of brain endothelial cells. Cell Microbiol 2012 0.87
54 Lipopolysaccharide-induced apoptosis in transformed bovine brain endothelial cells and human dermal microvessel endothelial cells: the role of JNK. J Immunol 2009 0.87
55 Plasmacytoid dendritic cells alter the antitumor activity of CpG-oligodeoxynucleotides in a mouse model of lung carcinoma. J Immunol 2010 0.86
56 Ubiquitination and de-ubiquitination: role in regulation of signaling by Toll-like receptors. J Endotoxin Res 2006 0.86
57 Plasmacytoid dendritic cells play a role for effective innate immune responses during Chlamydia pneumoniae infection in mice. PLoS One 2012 0.85
58 Villous B cells of the small intestine are specialized for invariant NK T cell dependence. J Immunol 2008 0.85
59 Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis. PLoS One 2013 0.85
60 Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells. PLoS One 2011 0.84
61 Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses. Am J Respir Cell Mol Biol 2009 0.84
62 Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling. J Immunol 2010 0.84
63 Marked acceleration of atherosclerosis after Lactobacillus casei-induced coronary arteritis in a mouse model of Kawasaki disease. Arterioscler Thromb Vasc Biol 2012 0.84
64 Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway. J Immunol 2011 0.82
65 Innate immunity, Toll-like receptors, and atherosclerosis: mouse models and methods. Methods Mol Biol 2009 0.82
66 Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Invest Ophthalmol Vis Sci 2011 0.82
67 Giant cell arteritis: dendritic cells take two T's to tango. Circ Res 2009 0.80
68 IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelination. PLoS One 2011 0.79
69 Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice. J Immunol 2013 0.77
70 Plasmacytoid dendritic cells modulate nonprotective T-cell responses to genital infection by Chlamydia muridarum. FEMS Immunol Med Microbiol 2010 0.77
71 Innate immunity, Toll-like receptors and host response to infection. Pediatr Infect Dis J 2005 0.77
72 Lipopolysaccharide, toll-like receptors, and the immune contribution to atherosclerosis. Arterioscler Thromb Vasc Biol 2005 0.76
73 Correction: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One 2015 0.75
74 The microbiome in asthma. Curr Opin Pediatr 2016 0.75