Methylated Genes in Sputum Among Older Smokers With Asthma.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 3425338)

Published in Chest on August 01, 2012

Authors

Akshay Sood1, Hans Petersen, Christopher M Blanchette, Paula Meek, Maria A Picchi, Steven A Belinsky, Yohannes Tesfaigzi

Author Affiliations

1: Department of Medicine, University of New Mexico School of Medicine, NM, USA.

Articles cited by this

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2007) 47.86

Standardization of Spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med (1995) 33.41

Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med (1999) 29.97

Interpretative strategies for lung function tests. Eur Respir J (2005) 21.50

Epidemiology Standardization Project (American Thoracic Society). Am Rev Respir Dis (1978) 14.41

The St George's Respiratory Questionnaire. Respir Med (1991) 8.49

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17

Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res (2000) 3.65

Overdiagnosis of asthma in obese and nonobese adults. CMAJ (2008) 3.23

Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res (2006) 3.05

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res (2002) 2.56

Prospective study of asthma in relation to smoking habits among 14,729 adults. Thorax (1988) 2.22

Gender-related differences in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2000) 2.20

Development of carcinoma of the lung as reflected in exfoliated cells. Cancer (1974) 2.20

Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Mol Cell Biol (1998) 2.17

Epigenetic regulation of airway inflammation. Curr Opin Immunol (2007) 1.66

Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers. Cancer Res (2006) 1.37

Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. Am J Respir Crit Care Med (2009) 1.35

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers. Carcinogenesis (2009) 1.25

Risk factors for asthma incidence. A review of recent prospective evidence. Panminerva Med (2004) 1.24

Identification of SULF2 as a novel transcriptional target of p53 by use of integrated genomic analyses. Cancer Res (2009) 1.18

Cigarette smoking and incidence of chronic bronchitis and asthma in women. Chest (1995) 1.18

Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers. COPD (2008) 1.16

Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. Am J Respir Crit Care Med (2010) 1.10

Epigenetic mechanisms and the relationship to childhood asthma. Eur Respir J (2010) 1.10

Incidence of asthma in adults--report from the Obstructive Lung Disease in Northern Sweden Study. Allergy (1997) 1.00

Epigenetics and obesity. Prog Mol Biol Transl Sci (2010) 0.99

Epigenetics and obesity: the devil is in the details. BMC Med (2010) 0.99

Risk factors for adult-onset asthma: a 14-year longitudinal study. Respirology (2009) 0.96

Epigenetics and environmental lung disease. Proc Am Thorac Soc (2010) 0.86

"Hands-on" regulation of B cell development by the transcription factor Pax5. Immunity (2007) 0.84

Articles by these authors

DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med (2008) 5.87

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res (2008) 5.05

Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins. Chest (2007) 4.96

Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov (2011) 4.60

An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med (2013) 4.49

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. N Engl J Med (2015) 4.16

MMP12, lung function, and COPD in high-risk populations. N Engl J Med (2009) 3.96

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle (2009) 3.05

EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res (2011) 2.32

Self-management programmes for COPD: moving forward. Chron Respir Dis (2012) 2.07

New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites. Am J Respir Crit Care Med (2011) 2.07

Burden of concomitant asthma and COPD in a Medicaid population. Chest (2008) 1.87

Gene promoter methylation in plasma and sputum increases with lung cancer risk. Clin Cancer Res (2005) 1.81

Defining a gene promoter methylation signature in sputum for lung cancer risk assessment. Clin Cancer Res (2012) 1.80

Spirometry and health status worsen with weight gain in obese smokers but improve in normal-weight smokers. Am J Respir Crit Care Med (2014) 1.77

The detection of chromosomal aneusomy by fluorescence in situ hybridization in sputum predicts lung cancer incidence. Cancer Prev Res (Phila) (2010) 1.73

Randomized phase III study of thoracic radiation in combination with paclitaxel and carboplatin with or without thalidomide in patients with stage III non-small-cell lung cancer: the ECOG 3598 study. J Clin Oncol (2012) 1.72

Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia. Am J Respir Crit Care Med (2011) 1.57

Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico. Am J Respir Crit Care Med (2013) 1.54

Cost-effectiveness of tolvaptan in autosomal dominant polycystic kidney disease. Ann Intern Med (2014) 1.52

Development and validation of a new global well-being outcomes rating scale for integrative medicine research. BMC Complement Altern Med (2004) 1.51

MUC1 in macrophage: contributions to cigarette smoke-induced lung cancer. Cancer Res (2013) 1.48

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25. Cancer Res (2008) 1.46

Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo. Cancer Res (2004) 1.45

Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Res (2008) 1.43

Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers. Cancer Res (2003) 1.39

17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway. Cancer Res (2006) 1.36

Depression and anxiety in women with breast cancer and their partners. Nurs Res (2006) 1.31

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. J Clin Invest (2013) 1.29

Potential benefits and problems with computerized prescriber order entry: analysis of a voluntary medication error-reporting database. Am J Health Syst Pharm (2006) 1.29

Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens. Cancer Res (2004) 1.28

MS-qFRET: a quantum dot-based method for analysis of DNA methylation. Genome Res (2009) 1.28

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers. Carcinogenesis (2009) 1.25

Selective cyclooxygenase-2 inhibition and cardiovascular effects: an observational study of a Medicaid population. Arch Intern Med (2005) 1.24

A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. Mol Pharmacol (2007) 1.23

Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells. Cancer Res (2008) 1.22

Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. Cancer Res (2008) 1.22

Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Mol Cancer Ther (2008) 1.22

Towards Clinical Application of Methylated DNA Sequences as Cancer Biomarkers: A Joint NCI's EDRN and NIST Workshop on Standards, Methods, Assays, Reagents and Tools. Cancer Res (2007) 1.21

Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Res (2004) 1.20

Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis. Mol Pharmacol (2009) 1.18

Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers. COPD (2008) 1.16

Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium. Am J Respir Crit Care Med (2004) 1.14

Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers. Cancer Res (2010) 1.14

Interdependent anxiety and psychological distress in women with breast cancer and their partners. Psychooncology (2007) 1.12

Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer. Cancer Res (2006) 1.12

Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression. Cancer Res (2003) 1.10

Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. Am J Respir Crit Care Med (2010) 1.10

Prenatal cigarette smoke decreases lung cAMP and increases airway hyperresponsiveness. Am J Respir Crit Care Med (2003) 1.09

An algorithm for the identification of undiagnosed COPD cases using administrative claims data. J Manag Care Pharm (2006) 1.09

The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas. Clin Cancer Res (2011) 1.09

Radiation-stimulated epigenetic reprogramming of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer. Dose Response (2009) 1.07

Economic assessment of initial maintenance therapy for chronic obstructive pulmonary disease. Am J Manag Care (2008) 1.06

Telephone interpersonal counseling with women with breast cancer: symptom management and quality of life. Oncol Nurs Forum (2005) 1.05

Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways. Carcinogenesis (2005) 1.04

IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis. J Immunol (2002) 1.04

The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death. J Cell Biol (2008) 1.04

Predicting the costs of managing patients with chronic obstructive pulmonary disease. Respir Med (2005) 1.03

Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers. Int J Cancer (2005) 1.03

Carcinogen exposure differentially modulates RAR-beta promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis. Carcinogenesis (2003) 1.02

Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. J Immunol (2008) 1.02

Severity of COPD at initial spirometry-confirmed diagnosis: data from medical charts and administrative claims. Int J Chron Obstruct Pulmon Dis (2011) 1.02

Deacetylation of p53 induces autophagy by suppressing Bmf expression. J Cell Biol (2013) 1.01

Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model. Cancer Res (2011) 1.01

Response of rats to low levels of sarin. Toxicol Appl Pharmacol (2002) 1.01

MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A (2013) 1.00

Softwares and methods for estimating genetic ancestry in human populations. Hum Genomics (2013) 1.00

Mechanistic basis for nonlinear dose-response relationships for low-dose radiation-induced stochastic effects. Nonlinearity Biol Toxicol Med (2003) 0.98

Health-related quality of life in individuals with chronic obstructive pulmonary disease. Heart Lung (2005) 0.98

Direct medical costs for complications among children and adults with diabetes in the US commercial payer setting. Appl Health Econ Health Policy (2014) 0.98

Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Res (2011) 0.97

Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies. Toxicol Sci (2009) 0.97

Radiation-induced lung adenocarcinoma is associated with increased frequency of genes inactivated by promoter hypermethylation. Radiat Res (2007) 0.97

Healthcare use and costs in patients with chronic bronchitis initiating maintenance therapy with fluticasone/salmeterol vs other inhaled maintenance therapies. Curr Med Res Opin (2009) 0.96

Adherence to controller therapy for chronic obstructive pulmonary disease: a review. Curr Med Res Opin (2010) 0.96